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Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will far exceed the simple embedded systems of today. CPS technology will transform the way people interact with engineered systems -- just as the Internet has transformed the way people interact with information. New smart CPS will drive innovation and competition in sectors such as agriculture, energy, transportation, building design and automation, healthcare, and manufacturing. The December 2010 report of the President's Council of Advisors on Science and Technology (PCAST) titled Designing a Digital Future: Federally Funded Research and Development in Networking and Information Technologycalls for continued investment in CPS research because of its scientific and technological importance as well as its potential impact on grand challenges in a number of sectors critical to U.S. security and competitiveness such as the ones noted above. These challenges and technology gaps are further described in aCPS Vision Statementpublished in 2012 by the federal Networking and Information Technology Research and Development (NITRD) CPS Senior Steering Group. Tremendous progress has been made in advancing CPS technology over the last five-plus years. We have explored foundational technologies that have spanned an ever-growing set of application domains, enabling breakthrough achievements in many of these fields. At the same time, the demand for innovation in these domains continues to grow, and is driving the need to accelerate fundamental research to

Humanity depends upon the Earth's physical resources and natural systems for food, energy, and water (FEW). However, both the physical resources and the FEW systems are under increasing stress. It is becoming imperative that we determine how society can best integrate social, ecological, physical and built environments to provide for growing demand for food, energy and water in the short term while also maintaining appropriate ecosystem services for the future. Known stressors in FEW systems include governance challenges, population growth and migration, land use change, climate variability, and uneven resource distribution. The interconnections and interdependencies associated with the FEW Nexus pose research grand challenges. To meet these grand challenges, there is a critical need for research that enables new means of adapting societal use of FEW systems. The INFEWS program seeks to support research that conceptualizes FEW systems broadly and inclusively, incorporating social and behavioral processes (such as decision making and governance), physical processes (such as built infrastructure and new technologies for more efficient resource utilization), natural processes (such as biogeochemical and hydrologic cycles), biological processes (such as agroecosystem structure and productivity), and cyber-components (such as sensing, networking, computation and visualization for decision-making and assessment). Investigations of these complex systems may produce discoveries that cannot emerge from research on food or energy or water systems alone. It is the synergy among these components in the context of sustainability that will open innovative science and engineering pathways to produce new knowledge, novel technologies, and innovative predictive capabilities.

Humanity depends upon the Earth's physical resources and natural systems for food, energy, and water (FEW). However, both the physical resources and the FEW systems are under increasing stress. It is becoming imperative that we determine how society can best integrate social, ecological, physical and built environments to provide for growing demand for food, energy and water in the short term while also maintaining appropriate ecosystem services for the future. Known stressors in FEW systems include governance challenges, population growth and migration, land use change, climate variability, and uneven resource distribution.The interconnections and interdependencies associated with the FEW Nexus pose research grand challenges. To meet these grand challenges, there is a critical need for research that enables new means of adapting societal use of FEW systems. The INFEWS program seeks to support research that conceptualizes FEW systems broadly and inclusively, incorporating social and behavioral processes (such as decision making and governance), physical processes (such as built infrastructure and new technologies for more efficient resource utilization), natural processes (such as biogeochemical and hydrologic cycles), biological processes (such as agroecosystem structure and productivity), and cyber-components (such as sensing, networking, computation and visualization for decision-making and assessment).

The goal of the CPS program is to develop the core system science needed to engineer complex cyber-physical systems that people can use or interact with and depend upon. Some of these may require high-confidence or provable behaviors. The program aims to foster a research community committed to advancing research and education in CPS and to transitioning CPS science and technology into engineering practice. By abstracting from the particulars of specific systems and application domains, the CPS program seeks to reveal cross-cutting fundamental scientific and engineering principles that underpin the integration of cyber and physical elements across all application sectors. To expedite and accelerate the realization of cyber-physical systems in a wide range of applications, the CPS program also supports the development of methods, tools, and hardware and software components based upon these cross-cutting principles, along with validation of the principles via prototypes and testbeds. We have also seen a convergence of CPS technologies and research thrusts that underpin Smart & Connected Communities (S&CC) and the Internet of Things (IoT). These domains offer new and exciting challenges for foundational research and provide opportunities for maturation at multiple time horizons.

The goal of the CPS program is to develop the core system science needed to engineer complex cyber-physical systems upon which people can depend with high confidence. The program aims to foster a research community committed to advancing research and education in CPS and to transitioning CPS science and technology into engineering practice. By abstracting from the particulars of specific systems and application domains, the CPS program aims to reveal cross-cutting fundamental scientific and engineering principles that underpin the integration of cyber and physical elements across all application sectors.  To expedite and accelerate the realization of cyber-physical systems in a wide range of applications, the CPS program also supports the development of methods, tools, and hardware and software components based upon these cross-cutting principles, along with validation of the principles via prototypes and test beds.

Recent advances in communications, computation, and sensing technologies offer unprecedented opportunities for the design of cyber-physical systems with increased responsiveness, interconnectivity and automation. To meet new challenges and societal needs, the Energy, Power, Control and Networks (EPCN) Program invests in systems and control methods for analysis and design of cyber-physical systems to ensure stability, performance, robustness, and security. Topics of interest include modeling, optimization, learning, and control of networked multi-agent systems, higher-level decision making, and dynamic resource allocation as well as risk management in the presence of uncertainty, sub-system failures and stochastic disturbances. EPCN also invests in adaptive dynamic programing, brain-like networked architectures performing real-time learning, and neuromorphic engineering. EPCN supports innovative proposals dealing with systems research in such areas as energy, transportation, and nanotechnology. EPCN places emphasis on electric power systems, including generation, transmission, storage, and integration of renewables; power electronics and drives; battery management systems; hybrid and electric vehicles; and understanding of the interplay of power systems with associated regulatory and economic structures and with consumer behavior. Also of interest are interdependencies of power and energy systems with other critical infrastructures. Topics of interest also include systems analysis and design for energy scavenging and alternate energy technologies such as solar, wind, and hydrokinetic. The program also supports innovative tools and test beds, as well as curriculum development integrating research and education. In addition to single investigator projects, EPCN encourages cross-disciplinary proposals that benefit from active collaboration of researchers with complementary skills.

Recent advances in communications, computation, and sensing technologies offer unprecedented opportunities for the design of cyber-physical systems with increased responsiveness, interconnectivity and automation. To meet new challenges and societal needs, the Energy, Power, Control and Networks (EPCN) Program invests in systems and control methods for analysis and design of cyber-physical systems to ensure stability, performance, robustness, and security. Topics of interest include modeling, optimization, learning, and control of networked multi-agent systems, higher-level decision making, and dynamic resource allocation as well as risk management in the presence of uncertainty, sub-system failures and stochastic disturbances. EPCN also invests in adaptive dynamic programing, brain-like networked architectures performing real-time learning, and neuromorphic engineering. EPCN supports innovative proposals dealing with systems research in such areas as energy, transportation, and nanotechnology. EPCN places emphasis on electric power systems, including generation, transmission, storage, and integration of renewables; power electronics and drives; battery management systems; hybrid and electric vehicles; and understanding of the interplay of power systems with associated regulatory and economic structures and with consumer behavior. Also of interest are interdependencies of power and energy systems with other critical infrastructures. Topics of interest also include systems analysis and design for energy scavenging and alternate energy technologies such as solar, wind, and hydrokinetic. The program also supports innovative tools and test beds, as well as curriculum development integrating research and education. In addition to single investigator projects, EPCN encourages cross-disciplinary proposals that benefit from active collaboration of researchers with complementary skills.

Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computation and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will expand the horizons of these critical systems. CPS technologies are transforming the way people interact with engineered systems, just as the Internet has transformed the way people interact with information. New, smart CPS drive innovation and competition in a range of application domains including agriculture, aeronautics, building design, civil infrastructure, energy, environmental quality, healthcare and personalized medicine, manufacturing, and transportation. Moreover, the integration of artificial intelligence with CPS creates new research opportunities with major societal implications. While tremendous progress has been made in advancing CPS technologies, the demand for innovation across application domains is driving the need to accelerate fundamental research to keep pace.

Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will far exceed the simple embedded systems of today. CPS technology will transform the way people interact with engineered systems -- just as the Internet has transformed the way people interact with information. New smart CPS will drive innovation and competition in sectors such as agriculture, energy, transportation, building design and automation, healthcare, and manufacturing.

Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will far exceed the simple embedded systems of today. CPS technology will transform the way people interact with engineered systems -- just as the Internet has transformed the way people interact with information. New smart CPS will drive innovation and competition in sectors such as agriculture, energy, transportation, building design and automation, healthcare, and manufacturing.

DARPA is soliciting innovative research proposals in the area of physical design of electronic circuits and systems. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems. The Design thrust of the Electronics Resurgence Initiative (ERI): Page 3 Investments will address today's System-On-Chip (SoC) design complexity and cost barriers, creating the environment needed for the next wave of US semiconductor innovation. Programs within this thrust will develop the algorithms and software required to realize a unified layout generator that will enable fully automated "no human in the loop" physical design of SoCs, system-in-packages (SiPs), and printed circuit boards (PCBs) in 24 hours. In parallel, programs will create the building blocks, validation methodologies, and infrastructure required for a scalable open source hardware ecosystem, bringing best practices in software to hardware design.

This Research Announcement (RA) solicits ground-breaking single-investigator proposals from junior faculty for research and development in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, and manufacturing of interest to DARPA's Biological Technologies Office (BTO), Defense Sciences Office (DSO) and Microsystems Technology Office (MTO).

This Research Announcement (RA) solicits ground-breaking single-investigator proposals from junior faculty for research and development in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, and manufacturing of interest to DARPA's Biological Technologies Office (BTO), Defense Sciences Office (DSO) and Microsystems Technology Office (MTO).

The National Science Foundation's Directorates for Computer and Information Science and Engineering (CISE), Engineering (ENG), and Mathematical and Physical Sciences (MPS) are coordinating efforts to identify bold new concepts with the potential to contribute towards significant improvements in the efficiency of radio spectrum utilization, protection of passive sensing services, and the ability for traditionally underserved Americans to benefit from current and future wireless-enabled goods and services. This EARS program solicitation seeks to fund innovative collaborative research addressing large-scale challenges that transcend the traditional boundaries of existing programs.

The National Science Foundation's Directorates for Computer and Information Science and Engineering (CISE), Engineering (ENG), and Mathematical and Physical Sciences (MPS) are coordinating efforts to identify bold new concepts with the potential to contribute towards significant improvements in the efficiency of radio spectrum utilization, protection of passive sensing services, and the ability for traditionally underserved Americans to benefit from current and future wireless-enabled goods and services. This EARS program solicitation seeks to fund innovative collaborative research addressing large-scale challenges that transcend the traditional boundaries of existing programs.

The Smart and Autonomous Systems (S&AS) program focuses on Intelligent Physical Systems (IPS) that are capable of robust, long-term autonomy requiring minimal or no human operator intervention in the face of uncertain, unanticipated, and dynamically changing situations. IPS are systems that combine perception, cognition, communication, and actuation to operate in the physical world. Examples include, but are not limited to, robotic platforms, self-driving vehicles, underwater exploration vehicles, and smart grids. Most current IPS operate in pre-programmed ways and in a limited variety of contexts. They are largely incapable of handling novel situations, or of even understanding when they are outside their areas of expertise. To achieve robust, long-term autonomy, however, future IPS need to be aware of their capabilities and limitations and to adapt their behaviors to compensate for limitations and/or changing conditions.

The Cyber-Physical Systems (CPS) program solicitation has been revised for FY 2018, and prospective Principal Investigators are encouraged to read the solicitation carefully. Among the changes are the following:

SoftwareInfrastructure for Sustained Innovation (SI2) is a long-term investment focused on realizing a portion of the Cyberinfrastructure Framework for 21st Century Science and Engineering (CIF21, http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=504730) vision and catalyzing new thinking, paradigms and practices in science and engineering. CIF21 envisions a linked cyberinfrastructure architecture that integrates large-scale computing, high-speed networks, massive data archives, instruments and major facilities, observatories, experiments, and embedded sensors and actuators, across the nation and the world, and that enables research at unprecedented scales, complexity, resolution, and accuracy by integrating computation, data, and experiments in novel ways. Software is a primary modality through which CIF21 innovation and discovery will be realized. It permeates all aspects and layers of cyberinfrastructure (from application codes and frameworks, programming systems, libraries and system software, to middleware, operating systems, networking and the low-level drivers). The CIF21 software infrastructure must address the complexity of this cyberinfrastructure, accommodating: disruptive hardware trends; ever-increasing data volumes; data integrity, privacy, and confidentiality; security; complex application structures and behaviors; and emerging concerns such as fault-tolerance and energy efficiency. The programs must focus on building robust, reliable and sustainable software that will support and advance sustained scientific innovation and discovery.
 The Division of Advanced Cyberinfrastructure in the Computer & Information Science & Engineering Directorate (CISE/ACI) is partnering with Directorates and Offices across the NSF to support SI2, a long-term comprehensive program focused on realizing a sustained software infrastructure that is an integral part of CIF21.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II). Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering. Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies. Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

The Dynamics, Control and Systems Diagnostics (DCSD) program supports fundamental research on the analysis, measurement, monitoring and control of dynamic systems. The program promotes innovation in the following areas: Modeling: creation of new mathematical frameworks to apply tools of dynamics to physical systems Analysis: discovery and exploration of structure in dynamic behavior Diagnostics: dynamic methods that infer system properties from observations Control: methods that produce desired dynamic behavior

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, social science, and manufacturing of interest to DARPA's Defense Sciences Office (DSO), Microsystems Technology Office (MTO), and Biological Technologies Office (BTO).

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, social science, and manufacturing of interest to DARPA's Defense Sciences Office (DSO), Microsystems Technology Office (MTO), and Biological Technologies Office (BTO).

DARPA Defense Sciences Office (DSO) wants to identify and pursue high-risk, high-payoff research initiatives across a broad spectrum of science and engineering disciplines and to transform these initiatives into important, radically new, game-changing technologies for U.S. national security. The current overarching office themes include accelerating scientific discovery, exploring fundamental limits, and expecting the unexpected. In support of this mission, the DSO Office-wide BAA invites proposers to submit innovative basic or applied research concepts in one or more of the following technical areas: Mathematics, Modeling and Design; Physical Systems; Human-Machine Systems; and Social Systems. Each of these areas is described below and includes a list of example research topics that highlight several (but not all) potential areas of interest. Proposals must investigate innovative approaches that enable revolutionary advances. DSO is explicitly not interested in approaches or technologies that primarily result in evolutionary improvements to the existing state of practice.

The Dynamics, Control and Systems Diagnostics (DCSD) program supports fundamental research on the analysis, measurement, monitoring and control of dynamic systems. The program promotes innovation in the following areas: -Modeling: creation of new mathematical frameworks to apply tools of dynamics to physical systems -Analysis: discovery and exploration of structure in dynamic behavior -Diagnostics: dynamic methods that infer system properties from observations -Control: methods that produce desired dynamic behavior

The Dynamics, Control and Systems Diagnostics (DCSD) program supports fundamental research on the analysis, measurement, monitoring and control of dynamic systems. The program promotes innovation in the following areas: -Modeling: creation of new mathematical frameworks to apply tools of dynamics to physical systems -Analysis: discovery and exploration of structure in dynamic behavior -Diagnostics: dynamic methods that infer system properties from observations -Control: methods that produce desired dynamic behavior