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This cooperative agreement will establish and maintain an interdisciplinary, multicenter research forum for scientific collaboration and infrastructure building, which will provide national leadership in research designed to improve the behavioral, mental, social, and/or cognitive health and wellbeing of children and adolescents with Autism Spectrum Disorder (ASD) and other developmental disabilities. As authorized by Section 399BB of the Autism CARES Act, the research network will determine the evidence-based practices for interventions to improve the behavioral health of individuals with ASD and other developmental disabilities, develop guidelines for those interventions, and disseminate information related to such research and guidelines. The AIR-B Network will be one of two HRSA-supported research networks that will provide national leadership in research to advance the evidence base on effective interventions for children and adolescents with ASD and other developmental disabilities, with AIR-B having a focus on addressing behavioral health and wellbeing. As directed by the FY 2015 Congressional Appropriations for HRSA's Autism CARES Act programs, HRSA is broadening the scope of this funding opportunity to reflect an additional emphasis on addressing disparities in effective interventions and treatment and access to care experienced by underserved minority and rural communities. In particular, applicants should consider diverse ethnic/racial, cultural, linguistic, socioeconomic, and geographic (e.g., rural/urban, tribal) populations for whom there is little evidence regarding the effectiveness of interventions, or for whom access to effective treatments is limited. Applicants should include plans to conduct multi-site research protocols on innovative treatment models, including the use of telehealth networks, to improve behavioral health interventions and treatment for ASD in underserved minority and rural communities. It is expected that the AIR-B Netwo

The purpose of this Funding Opportunity Announcement is to support the discovery and development of medications to prevent and treat opioid use disorders (OUD) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. UG3 projects that have met their milestones will be administratively considered by NIDA and prioritized for transition to the UH3 phase. Investigators responding to this FOA must address both UG3 and UH3 phases. Application may include preclinical or clinical research studies that will have high impact and quickly yield the necessary results to advance closer to FDA approval medications that are safe and effective to prevent and treat OUDs and overdose. The compounds to be evaluated can be small molecules or biologics. They can be tested in pre-clinical models and/or for the clinical manifestations of OUDs such as withdrawal, craving, relapse, or overdose. Applications may focus on the development of new chemical entities, new formulations of marketed medications available for other indications, or combinations of medications that hold promise for the treatment of OUDs and overdose. Through this FOA, NIDA seeks to fast-track the discovery and development of medications to prevent and treat OUDs or opioid overdose and to advance them in the FDA's drug development approval pipeline. This project is part of the NIH initiative to establish a public-private partnership to address the opioid crisis via more effective and safe ways to prevent and treat opioid use disorders and overdose. https://www.nih.gov/opioid-crisis

Beginning in FY2015, Congress appropriated $1,000,000 for the WWSDP to fund a competitive grants program. This program continues in FY2019 under the authority of the Defense Health Program, Operations & Maintenance, therapeutic service dog training program. The Uniformed Services University of the Health Sciences (USU) is authorized by 10 U.S.C. 2113(g)(1)(A) to make grants to any nonprofit entity. Historically, USU has solicited grant applications from nonprofit institutions committed to connecting service dogs with service members and veterans. USU obligated $1,000,000 in FY2015, $5,000,000 in FY2016, and FY2017 and $10,000,000 in FY2018 to carry out this program. USU intends to award multiple, 12-month grants (subject to availability of funding) to eligible nonprofit organizations to continue this program in FY2019. USU plans to obligate approximately $10,000,000 in grants to successful applicants for the WWSDP in FY2019. The number of grants to be awarded and the amount of funding per grant is to be determined based upon the quality of the applications. On average, since the Program's inception, USU awarded grants to 21 Recipients with an average funding amount of approximately $251,500 per award with awards ranging from $45,000 to $586,800. Funding provided through this program is not intended to finance new programs or initiatives, but to support the operations of existing programs. The planned period of performance for the FY2019 WWSDP is June 2019 through June 2020. Past Recipients of WWSDP grants are eligible to apply and compete for FY2019 WWSDP grants; however, applications for renewal or supplementation of existing awards will not be considered.

Focus on Short-term Risk for Suicide (up to $1.5 million over 3 years):Letter of Intent required for this application.  AFSP offers Suicide Research Grants in six categories. Distinguished Investigator Grants (up to $100,000 over 2 years):Grants awarded to investigators at the level of associate professor or higher with an established record of research and publication on suicide.  Standard Research Grants (up to $90,000 over 2 years):Grants awarded to individual investigators at any level. Linked Standard Research Grants (up to $225,000 over 2 years):Grants awarded to investigators at any level performing research involving three or more unique sites. Young Investigator Grants (up to $85,000 over 2 years):Grants awarded to investigators at or below the level of assistant professor. These grants must allocate $10,000 ($5,000 per year) of their award for an established suicide researcher to mentor the Young Investigator. AFSP is available to assist you in identifying a suitable mentor.  Postdoctoral Research Fellowships (up to $104,000 over 2 years):Grants awarded to investigators who have received a Ph.D., M.D., or other doctoral degree within the preceding six years and have had no more than three years of fellowship support. Fellows receive a stipend of $46,000 per year and an institutional allowance of $6,000 per year.  Pilot Grants (up to $30,000 over one or two years):Awarded to investigators at any level, these grants provide seed funding for new projects that have the potential to lead to larger investigations. These grants typically entail feasibility studies rather than hypothesis-driven research. 

Organizations -- private and public, established and entrepreneurial, designed and emergent, formal and informal, profit and nonprofit -- are critical to the well-being of nations and their citizens. They are of crucial importance for producing goods and services, creating value, providing jobs, and achieving social goals. The Science of Organizations (SoO) program funds basic research that yields a scientific evidence base for improving the design and emergence, development and deployment, and management and ultimate effectiveness of organizations of all kinds. SoO funds research that advances our fundamental understanding of how organizations develop, form and operate. Successful SoO research proposals use scientific methods to develop and refine theories, to empirically test theories and frameworks, and to develop new measures and methods. Funded research is aimed at yielding generalizable insights that are of value to the business practitioner, policy-maker and research communities. SoO welcomes any and all rigorous, scientific approaches that illuminate aspects of organizations as systems of coordination, management and governance. In considering whether a particular project might be a candidate for consideration by SoO, please note: Intellectual perspectives may involve (but are not limited to) organizational theory, behavior, sociology or economics, business policy and strategy, communication sciences, entrepreneurship, human resource management, information sciences, managerial and organizational cognition, operations management, public administration, social or industrial psychology, and technology and innovation management. Phenomena studied may include (but are not limited to) structures, routines, effectiveness, competitiveness, innovation, dynamics, change and evolution.Levels of analysis may include (but are not limited to) organizational, cross-organizational collaborations or relationships, and institutional and can address individuals, groups or tea

A cancer survivor is a person diagnosed with cancer, from the time of diagnosis throughout the person’s lifespan. As of 2008, nearly 12 million cancer survivors were living in the United States; this number is expected to increase to 18 million in 2020. Cancer survivors have long-term adverse physical and psychosocial effects from their diagnosis and treatment, and have a greater risk for additional cancer diagnoses compared with persons without a cancer history. Cancer survivors commonly report negative behavioral, medical, and health care access issues that may contribute to poor long-term medical and psychosocial outcomes. An analysis of over 45,000 U.S. cancer survivors showed that: 1) 15% of cancer survivors continue to use tobacco; 2) 20-25% do not receive recommended cancer screenings; 3) 31% do not engage in any leisure time physical activity; 4) 40 to 50% do not receive flu or pneumonia vaccines; 5) 60% do not have a summary of their cancer treatment; and 6) 25% do not have any instructions (written or oral) for their treatment or follow-up care . CDC’s National Comprehensive Cancer Control Program (NCCCP) supports collaborative cancer control and prevention efforts in all states, the District of Columbia, tribal organizations, territories, and Pacific Island jurisdictions to address the cancer burden in their jurisdictions. In 2010, NCCCP developed six priorities areas of focus for the greatest public health impact; one of the six priorities is to address the public health needs of cancer survivors. The purpose of this FOA is to implement a broad set of evidence-based survivorship strategies in a subset of NCCCP grantees that will have the short-term results of increasing knowledge of cancer survivor needs, increasing survivor knowledge of treatment and follow-up care, and increasing provider knowledge of guidelines pertaining to treatment of cancer. Intermediate outcomes include the development of best practices in survivorship among NCCCP gra

The purpose of this FOA is to fund research centers that will establish longitudinal cohorts in rare HLBS diseases to investigate unaddressed research questions using epidemiologic study designs and methods that are appropriate for conditions affecting fewer than 200,000 persons in the US. These observational cohort studies should be designed to provide an evidence base for future interventional studies, including clinical trials; for developing better diagnostics than those that are currently available; for answering early translational questions; or for broader implementation of guidelines for managing these diseases. This program will provide opportunities to advance rare disease research using genetics and deep phenotyping to characterize the disease and to identify disease sub-types; to use data science methods that integrate clinical and patient-reported outcomes (PROs) with laboratory, imaging, environmental and -omics data to understand the natural history of disease; to generate data that differentiate patients with the same morphological phenotype but different genetic mutations and severity of outcomes; to elucidate genotype-phenotype interactions and multisystem phenotyping to develop reliable and valid predictive tools to determine who will respond to which treatments and when to intervene; and to encourage innovative methods such as telemedicine to include participants with rare diseases located in remote locations.

The Society for The Teaching of Psychology (Division 2 of APA) is pleased to announce a program of small grants to promote communication and collaboration between psychology teachers from different institutions. Specifically, this program is intended to bring together individuals to engage in planned activities to promote the teaching of psychology or who desire to work together to think about the ways in which the teaching of psychology can be improved. Proposed activities could take the form of conferences or small meetings devoted to teaching-related topics, or could take the form of collaborative activities between specific individuals from different institutions that are intended to improve the teaching of psychology in some way (e.g., bringing together high school and college psychology students for an interactive or experiential program, development of programs devoted to mentoring future psychology teachers, programs to bring together and utilize specialized teaching resources from different institutions). Grant funds can be used to defray the costs of the collaborative activities or the meetings involving representatives from different institutions (e.g., materials, equipment, fees, travel, food). Activities funded by this program may result in peer-reviewed publications, but do not necessarily have to have this goal. Research collaborations that focus on the Scholarship of Teaching and Learning (SoTL) are no longer eligible for funding through this grant program; those interested in obtaining funding to support SoTL should apply to STP's "Scholarship of Teaching and Learning Research Grant" program. Non-SoTL research collaborations that include a significant teaching component can be submitted for consideration; proposals for research collaborations that will have no impact on teaching or include no teaching-related activities are also not appropriate for this program.

As defined in the DD Act of 2000, the term "developmental disabilities" means a severe, chronic disability of an individual that is attributable to a mental or physical impairment or combination of mental and physical impairments that are manifested before the individual attains age 22 and are likely to continue indefinitely. Developmental disabilities result in substantial limitations in three or more of the following functional areas: self-care, receptive and expressive language, learning, mobility, self-direction, capacity for independent living and economic self-sufficiency. The DD Act of 2000 identifies a number of significant findings, including: Disability is a natural part of the human experience that does not diminish the right of individuals with developmental disabilities to enjoy the opportunity for independence, productivity, integration and inclusion into the community. Individuals whose disabilities occur during their developmental period frequently have severe disabilities that are likely to continue indefinitely. Individuals with developmental disabilities often require lifelong specialized services and assistance, provided in a coordinated and culturally competent manner by many agencies, professionals, advocates, community representatives and others to eliminate barriers and to meet the needs of such individuals and their families. The DD Act of 2000 also promotes the best practices and policies presented below: Individuals with developmental disabilities, including those with the most severe developmental disabilities, are capable of achieving independence, productivity, integration and inclusion into the community, and often require the provision of services, supports and other assistance to achieve such. Individuals with developmental disabilities have competencies, capabilities and personal goals that should be recognized, supported and encouraged, and any assistance to such individuals should be provided in an individualized manner, consisten

This funding opportunity announcement (FOA) seeks to develop and nurture a national innovation ecosystem that builds upon biomedical research to develop technologies, products and services that benefit society. Toward meeting this objective, the I- Corps™ program is being offered. The I-Corps™ at NIH program is focused on educating researchers and technologists on how to translate technologies from the lab into the marketplace. Under this FOA, participating NIH and CDC Institutes and Centers will provide administrative supplement awards to two cohorts of currently-funded SBIR and STTR Phase I grantees to support entrepreneurial training under the I-Corps™ at NIH Program. The program is designed to provide three-member project teams with access to instruction and mentoring in order to accelerate the translation of technologies currently being developed with NIH and CDC SBIR and STTR funding. It is anticipated that outcomes for the I-Corps™ teams participating in this program will include significantly refined commercialization plans and well-informed pivots in their overall commercialization strategies. Prospective applicants are strongly encouraged to contact NIH or CDC Scientific/Research staff for more information about the program before applying.

This funding opportunity announcement (FOA) seeks to develop and nurture a national innovation ecosystem that builds upon biomedical research to develop technologies, products and services that benefit society. Toward meeting this objective, the I- Corps™ program is being offered. The I-Corps™ at NIH program is focused on educating researchers and technologists on how to translate technologies from the lab into the marketplace. Under this FOA, participating NIH and CDC Institutes and Centers will provide administrative supplement awards to two cohorts of currently-funded SBIR and STTR Phase I grantees to support entrepreneurial training under the I-Corps™ at NIH Program. The program is designed to provide three-member project teams with access to instruction and mentoring in order to accelerate the translation of technologies currently being developed with NIH and CDC SBIR and STTR funding. It is anticipated that outcomes for the I-Corps™ teams participating in this program will include significantly refined commercialization plans and well-informed pivots in their overall commercialization strategies. Prospective applicants are strongly encouraged to contact NIH or CDC Scientific/Research staff for more information about the program before applying.

The awards pursuant to this Notice of Funding Opportunity are contingent upon the availability of funds. The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research that will help expand and advance our understanding about what works to prevent overdose from prescription and illicit opioids by developing and piloting, or rigorously evaluating novel primary or secondary prevention interventions. The intent of this Notice of Funding Opportunity (NOFO) is to: (1) build the scientific base for the primary or secondary prevention of opioid overdose, and (2) encourage collaboration of scientists from a spectrum of disciplines including public health, epidemiology, law enforcement, social work, economics, and criminal justice to perform research that can identify ways to prevent opioid overdose more effectively. Interventions can be strategies, programs, or policies. Ultimately, this research is intended to improve state and local health departments’ ability to implement and improve interventions focused on preventing opioid-related deaths. Researchers are expected to develop and pilot, or rigorously evaluate novel primary or secondary prevention interventions that address prescription or illicit opioid overdose. Primary prevention approaches are expected to aim to prevent opioid misuse, abuse, and overdose before it occurs. Secondary prevention approaches are expected to focus on the more immediate responses to opioid overdose, such as emergency department services and linkage to treatment immediately following a nonfatal overdose.

Major League Baseball and the Major League Baseball Players Association are launching the Healthy Relationships Community Grants initiative to address positive relationship health, with self and others. The initiative will focus on three distinct areas: 1. Build and improve relationship skills of the next generation as a prevention strategy. Organizational efforts may include, but are not limited to, the following: -Educate the public (with a preference for youth populations) on the difference between healthy and unhealthy relationships as it relates to inter-personal violence (e.g., intimate partner, family, or teen dating violence) as part of prevention and awareness efforts (e.g., Create, produce and distribute PSAs with relevant content and call to action, Conference/events with a focus on education) -Support existing or introduce new programming on how to break the cycle of violence 2. Build and improve mental health resiliency for vulnerable populations. Organizational efforts may include, but are not limited to, the following: - Provide greater access to quality mental health services and wellness programs - Preventative programs designed to reduce suicide, suicidal ideations and self-harm - Training programs for mental health professionals working with vulnerable populations - School or community-based interventions for vulnerable populations 3. Strengthen and provide critical services to survivors of domestic violence. Organizational efforts may include, but are not limited to, the following: - Capacity building to support organizational mission - Mental health services for survivors of domestic violence - Assist survivors in rebuilding their lives (e.g., professional skills and life skills workshops, Additional education and support materials to improve employee readiness/workplace development skills) - Advocacy efforts to reduce domestic violence, dating violence, sexual assault, and stalking

This targeted 5-year cooperative agreement is to be awarded to create a national center of excellence to develop, implement and evaluate curriculum in child welfare agency settings that will: Support the child welfare workforce to better understand social and emotional needs of children and families involved in the child welfare system. Support the child welfare workforce to better screen and assess for social and emotional needs of children and families. Support the child welfare workforce to understand the effective interventions and active ingredients of those interventions and how to ensure children and families receive those interventions. Increase exposure to active ingredients and Evidence Based Practices for agency staff through enhanced curriculum and practicums. Provide professional development opportunities for agency staff by developing, delivering, and evaluating course offerings, continuing education, and certificate programs aimed at addressing the shortage of child welfare practitioners prepared to deliver evidence based child and family treatment. Provide curriculum aimed at assisting case managers to make excellent decisions about how to refer and evaluate the effectiveness of the services provided to the children and families in their care. Develop decision making tools for agency leadership that might assist them in assessing their current mental health service array. These tools would provide direction about the cost and effectiveness of the mental health services in their current service array, assist the administrator in evaluating if the current mental health services are achieving intended outcomes, and provide guidance on best practice in implementing evidence based treatment services.

The APF Alexander Gralnick Research Investigator Prize recognizes "exceptional individuals working in the area of serious mental illness," including but not limited to schizophrenia, bipolar disorder, and paranoia (delusional disorder). The prize was established to honor the late Alexander Gralnick, MD, and to reflect the breadth of his accomplishments and contributions in the field of serious mental illness. Dr. Gralnick was a Life Fellow of the American Psychiatric Association, and he received the American Psychiatric Association's Distinguished Service Award and the Service to the Mentally Ill Award of the World Association for Psychosocial Rehabilitation. The prize aims to carry on Dr. Gralnick's legacy by facilitating research by doctoral-level investigators in the area of serious mental illness. Goals: To encourage psychologists to assume a leadership role for psychology in the area of serious mental illness.To encourage the training of future psychologists to become leaders in this field.To provide funding for recipients to ensure that psychologists work to advance understanding and treatment for those who are affected by serious mental illnesses.

The NIJ Graduate Research Fellowship (GRF) program in Social and Behavioral Sciences is open to doctoral students in all social and behavioral science disciplines. This program provides awards to accredited academic institutions to support graduate research leading to doctoral degrees in areas that are relevant to ensuring public safety, preventing and controlling crime, and ensuring the fair and impartial administration of criminal justice in the United States. NIJ invests in doctoral education by supporting academic institutions that sponsor students who demonstrate the potential to successfully complete doctoral degree programs in disciplines relevant to the mission of NIJ and who are in the final stages of graduate study. Applicants sponsoring doctoral students are eligible to apply only (1) if the doctoral student'‚ƒƒ™s degree program is a Social and Behavioral Science discipline and (2) if the student's proposed dissertation research has direct implications for criminal justice policy and practice in the United States.

The NIJ Graduate Research Fellowship (GRF) program in Social and Behavioral Sciences is open to doctoral students in all social and behavioral science disciplines. This program provides awards to accredited academic institutions to support graduate research leading to doctoral degrees in areas that are relevant to ensuring public safety, preventing and controlling crime, and ensuring the fair and impartial administration of criminal justice in the United States. NIJ invests in doctoral education by supporting academic institutions that sponsor students who demonstrate the potential to successfully complete doctoral degree programs in disciplines relevant to the mission of NIJ and who are in the final stages of graduate study. Applicants sponsoring doctoral students are eligible to apply only (1) if the doctoral student'‚ƒƒ™s degree program is a Social and Behavioral Science discipline and (2) if the student's proposed dissertation research has direct implications for criminal justice policy and practice in the United States.

This Funding Opportunity Announcement (FOA) is intended to stimulate model-driven research to understand the ways that people make decisions about engaging in behaviors that impact the risk of acquiring or transmitting HIV, or to adhere to treatments for HIV. Decision making processes may contribute to both substance use/abuse and other HIV acquisition or transmission risks. A better understanding of decision making processes in the context of brain neural networks and their associated functions would lead to the development of better strategies to reduce the frequency of HIV-risk behaviors. Therefore, this FOA encourages applications to study 1) cognitive, motivational or emotional mechanisms and/or 2) brain neuroendocrine and reinforcement systems that related to HIV-risk behaviors or treatment non-compliance. Interdisciplinary studies that incorporate approaches from psychology, economics, anthropology, sociology, decision sciences, neuroscience and computational modeling are encouraged. This FOA for R21 applications is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact.

The Substance Abuse and Mental Health Services Administration, Center for Mental Health Services is accepting applications for fiscal year (FY) 2015 Campus Suicide Prevention grants. The purpose of this program is to facilitate a comprehensive public health approach to prevent suicide in institutions of higher education. The grant is designed to assist colleges and universities in building essential capacity and infrastructure to support expanded efforts to promote wellness and help-seeking of all students. Additionally, this grant will offer outreach to vulnerable students, including those experiencing substance abuse and mental health problems who are at greater risk for suicide and suicide attempts. The Campus Suicide Prevention grant supports a wide range of program activities and prevention strategies to build and sustain a foundation for mental health promotion, suicide prevention, substance abuse prevention and other prevention activities such as interpersonal violence and by-stander interventions. As an Infrastructure Development grant, funds cannot be used to pay for direct traditional mental health and substance abuse treatment services such as therapy, counseling, and medication management. The Campus Suicide Prevention Grant program seeks to address behavioral health disparities among racial, ethnic, sexual and gender minorities by encouraging the implementation of strategies to decrease the differences in access, service use and outcomes among the racial and ethnic minority populations served. (See PART II: Appendix G - Addressing Behavioral Health Disparities.) SAMHSA intends that these grants will assist colleges and universities to have a campus free from the tragedy of suicide which also supports the National Strategy for Suicide Prevention Objective 8.1 (See http://store.samhsa.gov/product/National-Strategy-for-Suicide-Prevention-2012-Goals-and-Objectives-for-Action/PEP12-NSSPGOALS). Campus Suicide Prevention grants are authorized under the Garre

The National Research Action Plan (NRAP) responding to Executive Order 13625, Improving Access to Mental Health Services for Veterans, Service Members, and Military Families (August 31, 2012), lays out a framework to ensure that Government funding agencies work together to further our knowledge and diagnostic/therapeutic capabilities with regard to post- traumatic stress disorder (PTSD), TBI, suicide, and related injuries by following longitudinal cohorts of Service members and Veterans. The DoD and VA ORD meet this directive through continued collaboration on and coordination of research efforts in the areas of TBI and PTSD. Additionally, recommendations from the DoD Blast Injury Research Program Coordinating Office's November 2015 International State of the Science Meeting (Does Repeated Blast- Related Trauma Contribute to the Development of Chronic Traumatic Encephalopathy (CTE)?) included pursuing longitudinal studies to evaluate links between blast-related TBI with CTE. While a number of longitudinal efforts are ongoing, the DoD and VA seek to pursue a mechanism to collaboratively streamline and continue longitudinal studies of mTBI in active duty and Veteran populations. The objective of this effort is to solicit a single Consortium of a large longitudinal study and supporting sub-studies to analyze a large TBI cohort to include Service members, Veterans, and relevant populations.

1) Innovative Challenge Grants - Six-month grants of $50,000 will be awarded to proposals with clear-cut deliverables defined within the application. If the deliverables are achieved, there's a possibility of a second tranche in the amount of $100,000 to $500,000 over twelve months. 2) Novel Discovery Grants - Proposals anywhere on the translational spectrum will be considered, including translation to humans, translation to patients, translation to practice, and translation to population health. Grants of $50,000 to $100,000 will be awarded for the first twelve months, with the option of an additional twelve months of support if significant progress is made. 3) Clinical and Social Science Challenge Grants - MoD seeks research that explores health equity in order to reduce disparities; opioid dependency in mom, dad, and baby to mitigate the rise in Neonatal Abstinence Syndrome; and premature birth and maternal/infant mortality. Sic-month grants of $50,000 to $100,000 will be awarded to proposals with clear-cut deliverables defined within the application. If the deliverables are achieved, there's a possibility of a second tranche in the amount of $100,000 to $500,000 over twelve months.

Supported by the NIH Common Fund (Common Fund) Science of Behavior Change (SOBC) Program, this Funding Opportunity Announcement (FOA) solicits competitive revision (formerly known as a competitive supplement) applications to NIH-supported clinical trials awarded as research project R34 grants. The goal of the SOBC Program is to advance a mechanisms-focused, experimental medicine approach to behavior change research. Funded projects in the SOBC Research Network (https://commonfund.nih.gov/behaviorchange/fundedresearch) have developed experimental manipulations, assays, and/or measures (hereafter referred to as assays for brevity) to support an experimental medicine approach to behavior change research. The SOBC Measures Repository is accessible from the SOBC Research Network Open Science Framework (OSF) page at https://osf.io/zp7b4. The goal of this FOA is to accelerate the adaptation, validation, and translation of SOBC Research Network assays for use in ongoing clinical trials. This FOA calls for the integration of SOBC Research Network assays into active NIH-supported clinical trials of drugs, devices, procedures, or behavior modifications. As such, the active NIH-supported clinical trial used to respond to this FOA does not have to be a behavior change trial or identify behavior change as a primary outcome. The integration of SOBC Research Network assays into ongoing clinical trials will accelerate the development of interventions and experimental manipulations that have been shown to engage specific mechanisms of behavior change and the development of assays that verify engagement of those behavior change targets.