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The Centers of Excellence on Environmental Health Disparities (EHD) research program is a collaborative effort supported by the National Institute on Minority Health and Health Disparities (NIMHD), the National Institute of Environmental Health Sciences (NIEHS), and the U.S. Environmental Protection Agency (EPA) that encourages basic, biological, clinical, epidemiological, behavioral and/or social scientific investigations of disease conditions that are known to be a significant burden in low socioeconomic and health disparate populations. The centers define environmental health disparities as inequities in illnesses that are mediated by disproportionate exposures associated with the social, natural and built environments. The kick-off meeting will feature presentations from each of the five funded centers highlighting their proposed research.

The goal of the Environmental Sustainability program is to promote sustainable engineered systems that support human well-being and that are also compatible with sustaining natural (environmental) systems.  These systems provide ecological services vital for human survival.  Research efforts supported by the program typically consider long time horizons and may incorporate contributions from the social sciences and ethics. The program supports engineering research that seeks to balance society's need to provide ecological protection and maintain stable economic conditions.

The goal of the Environmental Sustainability program is to promote sustainable engineered systems that support human well-being and that are also compatible with sustaining natural (environmental) systems.  These systems provide ecological services vital for human survival.  Research efforts supported by the program typically consider long time horizons and may incorporate contributions from the social sciences and ethics. The program supports engineering research that seeks to balance society's need to provide ecological protection and maintain stable economic conditions.

This Funding Opportunity Announcement (FOA) seeks to stimulate and expand research on the interplay of genetic and environmental factors in the genesis, course, and outcomes of substance and alcohol use disorders (SUDs). Previous work in genetic epidemiology and molecular genetics has established that SUDs are highly heritable, developmental disorders with important genetic substrates.Building on these findings, new studies using genetically informative approaches are needed to elucidate the complex interplay of genetic and environmental factors in developmental trajectories of SUDs and comorbid conditions, deepen and refine phenotypic definitions of SUDs, and meet the methodologic challenges of the field.Such studies hold great potential to promote understanding of the true contributions of both genetic and environmental factors to initiation, progression, comorbidity, adverse outcomes, and cessation of SUDs; to elucidate mechanisms of risk; and to enhance opportunities for translation to treatment, prevention, gene-finding and molecular studies.

This Funding Opportunity Announcement (FOA) seeks to stimulate and expand research on the interplay of genetic and environmental factors in the genesis, course, and outcomes of substance and alcohol use disorders (SUDs). Previous work in genetic epidemiology and molecular genetics has established that SUDs are highly heritable, developmental disorders with important genetic substrates.Building on these findings, new studies using genetically informative approaches are needed to elucidate the complex interplay of genetic and environmental factors in developmental trajectories of SUDs and comorbid conditions, deepen and refine phenotypic definitions of SUDs, and meet the methodologic challenges of the field.Such studies hold great potential to promote understanding of the true contributions of both genetic and environmental factors to initiation, progression, comorbidity, adverse outcomes, and cessation of SUDs; to elucidate mechanisms of risk; and to enhance opportunities for translation to treatment, prevention, gene-finding and molecular studies.

Research program focus areas identified by the foundation include: Pediatric Health - Projects that promote health and prevent or treat disease. Of particular interest are applied research projects focused on reducing the incidence of neonatal and early childhood illnesses, or those aimed at improving cognitive, social, and emotional aspects of development. Pediatric Nutrition - Projects that assure adequate nutrition to infants and young children, including applied research that evaluates the provision of specific nutrients and their related outcomes. Environmental Hazards (Nutrient Competitors) - Projects that document the impact of, or ameliorate the effects of, environmental hazards on the growth and development of infants and young children. Major target areas for research include new diagnostic tools that might be more rapid, more specific, more sensitive, or less invasive; treatment regimens that are novel, less stressful or painful, more targeted, have fewer side effects, and/or provide optimal dosing; symptom relief; preventative measures; assessment of deficiencies or excesses (vitamins, minerals, drugs, etc.); and risk assessment tools or measures for environmental hazards, trauma, etc. The foundation is interested in supporting projects that will result in "new" information, treatments, or tools that result in a change in practice; it rarely funds projects that are focused on sharing current information with parents or caregivers.

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative research to understand uniquely associated factors (biological, behavioral, sociocultural, and environmental) that contribute to health disparities or health advantages among U.S. immigrant populations.  

The goal of this NIEHS undergraduate research education R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce in the environmental health sciences. To this end, this funding opportunity announcement (FOA) encourages the development of creative educational activities with a primary focus on research experiences for undergraduates at the junior and senior level.

The goal of this FOA is to test whether or not the ages of laboratory animals is an important consideration in experimental outcomes in the study of disease pathology, degenerative condition, response to therapy, intervention or environmental exposure. The majority of studies of human conditions and diseases in laboratory animals are done using young animals. 

This Funding Opportunity Announcement invites applications for a U24 Telomere Research Network/Collaboratory. This U24 will coordinate activities of a telomere length (TL) methods comparison study involving multiple labs supported under U01 awards made in response to FOA (RFA-AG-19-023) to address the need for cross-validation between protocols and samples for establishing best practices for population-based TL research. The U24 will serve as the central resource for the organization of meetings and other activities of this coordinated program, including support for the methods study, dissemination of its results and resultant recommendations. It will also develop and foster an extended Telomere Research Network (TRN) connecting the broader field through a flexible range of activities that will advance an interdisciplinary research agenda on telomeres and activities directly associated with TL maintenance as sentinels of environmental exposures, psychosocial stress, and disease susceptibility.

This Funding Opportunity Announcement (FOA) encourages applications from investigators that propose to study the developing brain or brain areas that play significant roles in mediating emotional and motivated behavior and in substance use and dependence.  All stages of brain development are of interest, but a new emphasis of the current reissue of this initiative is to support basic neuroscience research on fundamental mechanisms of brain development during prepuberty and the adolescent period in relation to the problems of substance abuse and co-morbidity with psychiatric disorders.  Topics of interest pertaining to brain development of this initiative include, but are not limited to, the euphoric properties of abused substances, actions of psychotherapeutic agents, and their consequences on memory, cognitive and emotional processes.  A major goal of this initiative is to understand how exposure to substances of abuse and environmental insults affects the cellular and molecular mechanisms underlying nervous system development and neural circuit functions implicated in substance use and addiction. 

The primary objective of this FOA is to stimulate innovative Convergent Neuroscience (CN) approaches to establish causal and/or probabilistic linkages across contiguous levels of analysis (e.g., gene, molecule, cell, circuit, system, behavior) in an explanatory model of psychopathology. In particular, applicants should focus on how specific constituent biological processes at one level of analysis contribute to quantifiable properties at other levels, either directly or as emergent phenomena.  Although not required, it is preferable that applications link at least three levels of analysis and include an emphasis on genetics. The projects under this FOA will develop novel methods, theories, and approaches through a CN team framework, bringing together highly synergistic inter/transdisciplinary teams from neuroscience and "orthogonal" fields (e.g., data/computational science, physics, engineering, mathematics, and environmental sciences). Successful teams will combine, expand upon, or develop conceptual frameworks and theoretical approaches, and build explanatory computational models that connect contiguous levels of analysis. Such frameworks, theories, and computational explanatory models should be validated through experimental approaches to elucidate biological underpinnings of complex behavioral (including cognitive and affective) outcomes in psychopathology. Additionally, a goal of this program is to advance research in CN by creating a shared community framework of resources which may be used by the broader research community to further research, as such, successful team will have robust plan for sharing data and other resources.

This Funding Opportunity Announcement (FOA) is issued by the National Institute of Neurological Disorders and Stroke (NINDS) in conjunction with the NIH Pain Consortium. It solicits R01 grant applications from institutions/organizations to perform innovative research that will elucidate the mechanisms underlying migraine, expand our current knowledge of the role of genetic, physiological, biopsychosocial, and environmental influences in migraine susceptibility and progression, and explore new therapeutic targets and therapies for acute migraine management and longer term prevention.

This Funding Opportunity Announcement (FOA) is issued by the National Institute of Neurological Disorders and Stroke (NINDS) in conjunction with the NIH Pain Consortium. It solicits R21 grant applications from institutions/organizations to perform innovative research that will elucidate the mechanisms underlying migraine, expand our current knowledge of the role of genetic, physiological, biopsychosocial, and environmental influences in migraine susceptibility and progression, and explore new therapeutic targets and therapies for acute migraine management and longer term prevention.

MOD invites all qualified scientists with faculty appointments or the equivalent, at universities, hospitals and research institutions (not for profit or profit), to submit applications for research grants relevant to our mission. This encompasses basic biological processes governing differentiation and development, genetics and genomics of these processes, clinical studies, reproductive health and environmental toxicology, and social and behavioral studies concerning cognitive and behavioral risks that affect outcomes of pregnancy, the perinatal period, and subsequent child development. Applications will be directed to one of three committees whose respective foci are:    * Cell Lineage and Differentiation  * Gene Discovery and Translational Medicine  * Social and Behavioral Sciences. This involves family units and includes genes, toxicants, social  determinants that adversely affect language or behavior, especially if involving premature  infants or children with birth defects.

The Foundation accepts applications for grants to conduct research on the effects of alcohol consumption on health and behavior. The following areas are of greater interest: Studies on how particular patterns of consumption (quantity of alcohol consumed, types of alcoholic beverages consumed, frequency of consumption and context) are related to health and behavioral outcomes. Interdisciplinary, bio-informatics, and other approaches to elucidate genetic and environmental factors that influence the patterns of consumption of alcoholic beverages and related consequences. The Foundation encourages basic and clinical research, including epidemiology. Examples of research topics include factors influencing underage drinking, mechanisms of alcohol-related organ injury, fetal alcohol spectrum disorders, and effects of alcohol on general health.   The Foundation gives preference to young investigators, but does not support students or trainees in pre- or post-doctoral programs. It does not fund thesis or dissertation research. Grants are made to academic and research institutions in the United States, Canada and South Africa, not to individuals. Evidence of support for the investigator from the institution is desirable. 

The purpose of this announcement is to support research to rigorously evaluate the effectiveness of primary prevention strategies for the perpetration of sexual violence. The National Center for Injury Prevention and Control's research priorities for sexual violence prevention include evaluating the efficacy and effectiveness of programs, strategies, and policies across all levels of the social ecology to prevent and interrupt the development of sexual violence perpetration. In addition, the Center's research priorities highlight the need to identify effective programs, strategies, and policies that might prevent multiple types of violence concurrently, including sexual violence, intimate partner violence, and other forms of violence, and evaluating the economic efficiency of such programs, strategies and policies. Research funded under this announcement will address these priorities by rigorously evaluating programs, strategies, or policies for their impact on rates of sexual violence perpetration in one of two areas: (a) strategies that engage boys and men, or (b) structural, environmental, and/or policy interventions. Although the primary focus of research conducted with these funds should be on reducing sexual violence perpetration, the inclusion of other violence-related outcomes (e.g., dating/intimate partner violence) is also encouraged.

This Funding Opportunity Announcement (FOA) issued by the Office of Behavioral and Social Sciences Research (OBSSR) and the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging (NIA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Environmental Health Sciences (NIEHS), the National Institute of General Medical Sciences (NIGMS), the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR) at the National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop basic and applied projects utilizing systems science methodologies relevant to human behavioral and social sciences and health. This FOA is intended to encourage a broader scope of topics to be addressed with systems science methodologies, beyond those encouraged by existing open FOAs. Research projects applicable to this FOA are those that are either applied or basic in nature (including methodological development), have a human behavioral and/or social science focus, and feature systems science methodologies

The goal of this FOA is to test whether or not the ages of laboratory animals is an important consideration in experimental outcomes in the study of disease pathology, degenerative condition, response to therapy, intervention or environmental exposure.

The purpose of this funding opportunity announcement (FOA) is to support projects that implement creative, efficient molecular epidemiologic approaches that incorporate individual genetic information, including polygenic as well as specific genetic risk variants, in existing large, population-based cohorts, registries and/or health systems to conduct analyses that advance our understanding of the complex etiology of severe mental disorders. The ultimate objective of this funding opportunity is the elucidation of the complex interplays of genetic (e.g., polygenic) risk, in addition to specific risk loci and networks, and environmental factors, in human populations, which will lead to better understanding, diagnosis, and ultimately treatment of mental disorders.

The ultimate objective of this funding opportunity is the elucidation of the complex interplays of genetic (e.g., polygenic) risk, in addition to specific risk loci and networks, and environmental factors, in human populations, which will lead to better understanding, diagnosis, and ultimately treatment of mental disorders. For a linked set of collaborative R01s, each site has its own Program Director(s)/Principal Investigator(s), and the program provides a mechanism for cross-site coordination and communication. Collaborative studies are appropriate to address research projects that go beyond the capacity of a single-site investigation, particularly to accommodate collaborations among sites with diverse expertise, perspectives, and contributions.?Specifically, the purpose of this funding opportunity announcement (FOA) is to support collaborative R01 projects from multidisciplinary teams that implement creative, efficient molecular epidemiologic approaches that incorporate individual genetic information, including polygenic as well as specific genetic risk variants, in existing large, population-based cohorts, registries and/or health systems to conduct analyses that advance our understanding of the complex etiology of severe mental disorders. Applicants wishing to submit individual l projects should apply to the companion FOA (link).