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The SD2 program aims to develop data-driven methods to accelerate scientific discovery and robust design in domains that lack complete models. Engineers regularly use high-fidelity simulations to create robust designs in complex domains such as aeronautics, automobiles, and integrated circuits. In contrast, robust design remains elusive in domains such as synthetic biology, neuro-computation, cyber, and polymer chemistry due to the lack of high-fidelity models. SD2 will develop tools to enable robust design despite the lack of complete scientific models.

The National Science Foundation (NSF) seeks to develop and nurture a national innovation ecosystem that builds upon research to guide the output of scientific discoveries closer to the development of technologies, products and processes that benefit society.