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The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reproductive and metabolic failure. The project is pertinent to multiple portfolios in the Fertility and Infertility Branch, e.g., basic ovarian biology, fertility preservation, assisted reproductive technology, spermatogenesis and sperm function, and therapeutic interventions to infertility. The emphasis on the gut microbiome and its impact on reproduction through its effects on HPG, HPA, and HPT axes leading to obesity, metabolic syndrome, stress disorders, infection and anxiety is also of interest to the Maternal and Pediatric infectious disease Branch, Pediatric Growth and Nutrition Branch and IDDB.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), through the Fertility and Infertility (FI) and the Gynecological, Health and Disease (GHD) Branches, provides funding for a limited number of research centers in the reproductive and gynecological sciences. For the purpose of this FOA, reproductive health includes both fertility/infertility and gynecological health. These centers provide an arena for multidisciplinary interactions among basic and clinical scientists interested in establishing high quality translational research programs in these scientific areas. The centers also serve as national resources for the training and career development of junior scientists electing to pursue biomedical research careers in reproductive health. Finally, center investigators develop and participate in community outreach and education efforts to increase awareness and convey the importance and implications of their research activities to the general public. The purpose of this FOA is to announce the re-competition of the National Centers for Translational Research in Reproduction and Infertility (NCTRI). The NCTRI will be administered through the Specialized Research Center (P50) award mechanism. These centers will form a national network that facilitates and accelerates bidirectional knowledge transfer between the laboratory and clinic with the ultimate goal of improving human reproductive and gynecological health through research excellence and innovation.

The program supports organizations that offer comprehensive, innovative, and unbiased sexual and reproductive health education to young women. The foundation is particularly interested in programs serving young women who are disadvantaged by poverty, discrimination, geographic isolation, lack of comprehensive sex education, hostile public policy, or other factors with potential to lead to inadequate sexual and reproductive health.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of puberty and the trajectory of sexual development. New technologies and approaches are needed to fill knowledge gaps and advance understanding of normative sexual development in both males and females. It is anticipated that the findings of studies supported by this FOA will advance knowledge of puberty and the establishment of reproductive competence

The Lesbian Health Fund (LHF), a program of GLMA: Health Professionals Advancing LGBT Equality, was established in 1992 to define, study, and educate lesbians and their health care providers about lesbian health issues. LHF's mission is to improve the health of lesbians, other sexual minority women (SMW) and their families through research. Research areas include: Understanding social, family, and interpersonal influences as sources of stress or support Eliminating inequalities in health care, including barriers to care, and improving quality of care and utilization rates Development and testing of interventions to address mental and physical health needs of lesbians and other SMW, including but not limited to depression, identity related issues, eating disorders, substance abuse, obesity, cancer risks, cardiovascular disease and sexually transmitted infections Sexual and reproductive health, including family & parenting issues The deadlines for receipt of applications are May 15 and October 15.

The primary purpose of the ASRM and SREI Research Grant Programs is to provide funds for new investigators to establish independent research programs. New investigators are those who have completed their training within the past three years and have independent faculty appointments at the commencement of the research. In special cases, ASRM will consider applications for bridge funding (i.e., between grant funding periods) for projects that are of benefit to other members of the Society, or for funding of new, highly innovative research projects by established investigators. Both the ASRM Research Grants, which are funded by the ASRM, and the SREI Research Grants, which are funded by SREI, are reviewed by the ASRM Research Committee. Grants in amounts of $10,000 to $50,000 will be considered for funding by the ASRM Board of Directors on an annual basis. A total of $200,000 is available for 2016. The SREI Board of Directors will fund one grant of up to $40,000. Funds are available for project expenses, technical assistance, patient expenses, research supplies and durable laboratory equipment. Up to ten percent (10%) of funds may be used for indirect costs or institutional overhead in circumstances deemed to be extraordinary by the Research Committee. Research grant funds may be expended over a 2-year time interval. If residual funds remain after 2 years, the principal investigator can apply for a no-cost extension. An individual should indicate which grant(s) he/she is applying for though he/she is eligible to receive only one grant.

The primary purpose of the ASRM and SREI Research Grant Programs is to provide funds for new investigators to establish independent research programs. New investigators are those who have completed their training within the past three years and have independent faculty appointments at the commencement of the research. In special cases, ASRM will consider applications for bridge funding (i.e., between grant funding periods) for projects that are of benefit to other members of the Society, or for funding of new, highly innovative research projects by established investigators. Both the ASRM Research Grants, which are funded by the ASRM, and the SREI Research Grants, which are funded by SREI, are reviewed by the ASRM Research Committee. Grants in amounts of $10,000 to $50,000 will be considered for funding by the ASRM Board of Directors on an annual basis. A total of $200,000 is available for 2016. The SREI Board of Directors will fund one grant of up to $40,000. Funds are available for project expenses, technical assistance, patient expenses, research supplies and durable laboratory equipment. Up to ten percent (10%) of funds may be used for indirect costs or institutional overhead in circumstances deemed to be extraordinary by the Research Committee. Research grant funds may be expended over a 2-year time interval. If residual funds remain after 2 years, the principal investigator can apply for a no-cost extension. An individual should indicate which grant(s) he/she is applying for though he/she is eligible to receive only one grant.