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This funding opportunity announcement (FOA) seeks to stimulate research that focuses on reducing negative individual and family outcomes related to unwanted transitions at the end of life and optimizing the individual and family outcomes related to high quality coordination of care of care of individuals who are enrolled in hospice. This FOA emphasizes individuals who are receiving hospice care and their family caregivers, in any setting where hospice care is provided, including their home, a relative's home, a hospice inpatient facility, an assisted living facility, a short- or long-term care facility, or a hospital.