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The Understanding the Rules of Life: Microbiome Theory and Mechanisms (URoL:MTM) program is an integrative collaborationacross Directorates and Offices within the National Science Foundation. The objective of URoL:MTM is to understand and establish the theory and mechanisms that govern the structure and function of microbiomes, a collection of microbes in a specific habitat/environment. This may include but is not limited to host-associated microbiomes, such as those with humans and other organisms, where i) the microbiome impacts host physiology, behavior, development, and fitness; ii) the host influences the metabolic activity, dynamics and evolution of the microbiome, and iii) the environment (biological, chemical, physical, and social) influences and is influenced by both the host and the microbiome. Recent progress has transformed our ability to identify and catalogue the microbes present in a given environment and measure multiple aspects ofbiological, chemical, physical, and social environments that affect the interactions among the members of the microbiome, the host, and/or habitat. Much descriptive and correlative work has been performed on many microbiome systems, particularly those in the human, soil, aquatic, and built environments. This research has resulted in new hypotheses about the microbiome's contributions to potential system function or dysfunction. The current challenge is to integrate the wide range of accumulated data and information and build on them to develop new causal/mechanistic models or theories of interactions and interdependencies across scales and systems.

The U.S. Environmental Protection Agency (EPA), through its Science to Achieve Results (STAR) program, seeks applications for research on how pollution affects human health in the context of the total Environment - built, natural, and social Environments interacting together with inherent characteristics and interactions. Proposed research should develop and test innovative models or impact assessment approaches to examine causal relationships of chemical pollutants and health effects with modifying interactions among the variables representing all of the major stressors and factors involved in a person's life. Proposals that integrate a diverse field of disciplines (social science, economics, epidemiology, engineering, Environmental science, biology, statistics, toxicology, chemistry, etc.) to address the complexity of the total Environment research problem are highly recommended.

Biological and Environmental Research (BER) of the Office of Science (SC), U.S. Department of Energy (DOE) hereby announces its interest in receiving applications for research of interest to the Genomic Science Program (http://genomicscience.energy.gov) in the following research areas: a) Integrating large-scale systems biology data to model, design, and engineer microbial systems for the production of biofuels and bioproducts: Interdisciplinary approaches to develop innovative, high-throughput modeling, genome-wide design and editing, and engineering technologies for a broad range of microbes relevant for the production of biofuels and bioproducts from biomass. b) Plant systems design for bioenergy: To develop novel technologies for genome-scale engineering to re-design bioenergy crops that can grow in marginal Environments while producing high yield of biomass that can be easily converted to biofuels and bioproducts. Applications should include strategies to address biocontainment, minimizing risks of potential release of engineered organisms into the Environment or other unintended outcomes.

Biological and Environmental Research (BER) of the Office of Science (SC), U.S. Department of Energy (DOE) hereby announces its interest in receiving applications for research of interest to the Genomic Science Program (http://genomicscience.energy.gov) in the following research areas: a) Integrating large-scale systems biology data to model, design, and engineer microbial systems for the production of biofuels and bioproducts: Interdisciplinary approaches to develop innovative, high-throughput modeling, genome-wide design and editing, and engineering technologies for a broad range of microbes relevant for the production of biofuels and bioproducts from biomass. b) Plant systems design for bioenergy: To develop novel technologies for genome-scale engineering to re-design bioenergy crops that can grow in marginal Environments while producing high yield of biomass that can be easily converted to biofuels and bioproducts. Applications should include strategies to address biocontainment, minimizing risks of potential release of engineered organisms into the Environment or other unintended outcomes.

The Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) will consider proposals for collaborative funding with the Electric Power Research Institute (EPRI), the Water Environment & Reuse Foundation (WE&RF) [formerly the Water Environment Research Foundation], and/or the Water Research Foundation (WRF). For a proposal to be considered for collaborative funding, the proposal must be submitted to the appropriate NSF-CBET program as an unsolicited proposal during the CBET unsolicited submission window, which is October 1, 2016 - October 20, 2016. The same dates will apply in future years. Proposals will be reviewed as part of the unsolicited program(s). Proposals must follow guidelines for the CBET program to which they are submitted. Proposals will be evaluated according to the NSF criteria of intellectual merit and broader impacts.

The Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) will consider proposals for collaborative funding with the Electric Power Research Institute (EPRI), the Water Environment & Reuse Foundation (WE&RF) [formerly the Water Environment Research Foundation], and/or the Water Research Foundation (WRF). For a proposal to be considered for collaborative funding, the proposal must be submitted to the appropriate NSF-CBET program as an unsolicited proposal during the CBET unsolicited submission window, which is October 1, 2016 - October 20, 2016. The same dates will apply in future years. Proposals will be reviewed as part of the unsolicited program(s). Proposals must follow guidelines for the CBET program to which they are submitted. Proposals will be evaluated according to the NSF criteria of intellectual merit and broader impacts.

In 2010, NSF established the Science, Engineering, and Education for Sustainability (SEES)1 investment area to lay the research foundation for decision capabilities and technologies aimed at mitigating and adapting to environmental changes that threaten sustainability. Some SEES investments advanced a systems-based approach to understanding, predicting, and reacting to stress upon, and changes in, the linked natural, social, and built environments. In this context, the importance of understanding the interconnected and interdependent systems involving food, energy, and water (FEW) has emerged. The NSF aims to specifically focus on advancing knowledge of the nitrogen and phosphorus cycles; the production and use of fertilizers for food production; and the detection, separation, and reclamation/recycling of nitrogen- and phosphorus-containing species in and from complex aqueous environments.

In 2010, NSF established the Science, Engineering, and Education for Sustainability (SEES)1 investment area to lay the research foundation for decision capabilities and technologies aimed at mitigating and adapting to environmental changes that threaten sustainability. Some SEES investments advanced a systems-based approach to understanding, predicting, and reacting to stress upon, and changes in, the linked natural, social, and built environments. In this context, the importance of understanding the interconnected and interdependent systems involving food, energy, and water (FEW) has emerged. The NSF aims to specifically focus on advancing knowledge of the nitrogen and phosphorus cycles; the production and use of fertilizers for food production; and the detection, separation, and reclamation/recycling of nitrogen- and phosphorus-containing species in and from complex aqueous environments.

The Environmental Engineering program is part of the Environmental Engineering and Sustainability cluster, which also includes 1) the Nanoscale Interactions program; and 2) the Environmental Sustainability program. Environmental engineering is an interdisciplinary field that applies chemical, biological, and physical scientific principles to protect human and ecological health. The goal of the Environmental Engineering program is tosupport potentially transformative fundamental research that applies scientific and engineering principles to 1) prevent, minimize, or re-use solid, liquid, and gaseous discharges of pollution to soil, water, and air by closing resource loops or through other measures; 2) mitigate the ecological and human-health impacts of such releases by smart/adaptive/reactive amendments or manipulation of the Environment, and 3) remediate polluted Environments through engineered chemical, biological, and/or geo-physical processes. Integral to achieving these goals is a fundamental understanding of the transport and biogeochemical reactivity of pollutants in the Environment.

The Challenge seeks designs that lead to the acquisition of academic, technical, and employability skills through engaging simulated experiences in the hybrid reality continuum. For the purpose of this notice, ``hybrid reality continuum'' refers to the range of computer-generated simulations that extend from completely simulated environments to environments that incorporate aspects of the real world. For the purpose of this Challenge, ``EdSim'' is broadly defined as computer-generated three-dimensional learning environments, including virtual, augmented, and mixed realities that draw upon or mimic real-world experiences and are designed to educate users.

The Program is pleased to announce that it is seeking proposals for funding to support forensic and biometric research and its application. The requested proposals should focus on DFBA activities and needs of the Program's other customers (AFMES, DC3, JPAC-CIL). Forensic research proposals should focus on the creation of new and improved field or laboratory functional capabilities that result in faster, more robust, more informative, less costly, or less labor-intensive recognition, identification, collection, preservation, and/or analysis of forensic evidence. Biometric research proposals should contribute to biometric applications or operations, including military functions such as combat identification (friend, foe, or neutral), offensive operations (intelligence support to targeting), force protection (physical access control), detention operations, civil-military operations (track target members of a population), personnel recovery and identification, and recognition and recovery of human remains. Proposals that will assist the DoD in achieving these goals are solicited, particularly proposals involving the development of equipment that is portable, sustainable, and useful in an expeditionary or field environment. The expeditionary and field environments require systems that are lightweight, portable, inexpensive, fast, and capable of operating in extreme environments of temperature, dust, humidity, etc. The systems must also be capable of secure data communications.

This Funding Opportunity Announcement (FOA) encourages applications for developing and testing innovative theories and computational, mathematical, or engineering approaches to deepen our understanding of complex social behavior. This research will examine phenomena at multiple scales to address the emergence of collective behaviors that arise from individual elements or parts of a system working together. Emergence can also describe the functioning of a system within the context of its environment. Often properties we associate with a system itself are in actuality properties of the relationships and interactions between a system and its environment. This FOA will support research that explores the often complex and dynamic relationships among the parts of a system and between the system and its environment in order to understand the system as a whole.

The Information Directorate of the Air Force Research Laboratory (AFRL/RI), Rome Research Site, is soliciting white papers under this announcement for innovative technologies to enable the effective management of information for military operations. Focus: The objective of this BAA is to develop and demonstrate middleware to bridge the tactical and enterprise domains, realizing decentralized IM services built upon client-based protocols for use at the tactical edge that can coexist and interoperate securely with the server-based IM services that are well-suited for deployment in enterprise-scale environments. To improve the exchange of information between enterprise and the tactical edge networks and applications, these services need to be capable of operating in contested/congested environments and be built upon disruption and fault tolerant techniques and technologies. The research and development to be conducted under this BAA is focused on the following: 1) Interoperable hybrid centralized & decentralized IM services designed for mobile operations. 2) Gateways for the exchange of heterogeneous information across disparate networks. 3) Disruption tolerant information preservation, optimized delivery, and synchronization. 4) Demonstration of the utility of these capabilities in operationally relevant environments.

Devices to maintain beauty are already available on the market. However, care provided by these devices is still limited to one based on the age or skin characteristics measured at special facilities. Devices for personalized treatment suitable for every individual condition and every environment is not yet provided. A personalized beauty care that incorporates innovative technologies is therefore supposed to possibly offer new beauty care experiences. The Client aims at building a device or service to meet any one of the following needs through cooperation with a partner: Allow individuals to grasp their beauty conditions and environment by using a device or service in an easy, speedy, and accurate manner at home. The beauty conditions include: skin conditions (e.g., wrinkles, blemishes, pores, texture, moisture content, sebum quantity, blood flow volume, color, elasticity, inflammation, pimples, porphyrin, desquamation, lymph, hidden blemishes, infiltration of cosmetics),  hair characteristics (e.g., temperature, moisture content, color, glow, electrostatic charge amount, pH, damages [e.g., cuticle peel-off, porosity, component balance, breakage, split hair], waviness, length, amount), and  beard characteristics (e.g., length, thickness, color, hair-raising angle, direction, ingrown hair, hairline).  The environment includes temperature, humidity, and ultraviolet quantity.

The program supports four main research thrusts that are envisioned to advance the goal of ubiquitous co-robots: scalability, customizability, lowering barriers to entry, and societal impact. Topics addressing scalability include how robots can collaborate effectively with multiple humans or other robots; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments. Customizability includes how to enable co-robots to adapt to specific tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics in lowering barriers to entry should focus on lowering the barriers for conducting fundamental robotics research and research on integrated robotics application. This may include development of open-source co-robot hardware and software, as well as widely-accessible testbeds. Outreach or using robots in educational programs do not, by themselves, lower the barriers to entry for robotics research. Topics in societal impact include fundamental research to establish and infuse robotics into educational curricula, advance the robotics workforce through education pathways, and explore the social, economic, ethical, and legal implications of our future with ubiquitous collaborative robots.

The Environmental Engineering program is part of the Environmental Engineering and Sustainability cluster together with 1) the Biological and Environmental Interactions of Nanoscale Materials program and 2) the Environmental Sustainability program. Environmental engineering is an interdisciplinary field that applies chemical, biological, and physical scientific principles to protect human and ecological health. The goal of the Environmental Engineering program is tosupport potentially transformative fundamental research that applies scientific and engineering principles to 1) prevent or minimize solid, liquid, and gaseous discharges of pollution to soil, water, and air; 2) mitigate the ecological and human-health impacts of such releases by smart/adaptive/reactive amendments or manipulation of the Environment, and 3) remediate polluted Environments through engineered chemical, biological, and/or geo-physical processes. Integral to achieving these goals is a fundamental understanding of the transport and biogeochemical reactivity of pollutants in the Environment. Therefore, research on Environmental micro/biology, Environmental chemistry, and Environmental geophysics may be relevant providing there is a clear connection to the application of Environmental engineering to protect human and ecological health.

CR1: Sensor Fusion · CR2: Machine Learning Systems for Wireless Cyber Environments · DD1: Research on emerging software development including · DD2: Reserved · DD3: Research and Development of laser propagation, energy density, manufacturing, control, beam forming, and related topics to lasers as weapons in a marine Environment · DD4: Research on analysis of mission engineering for emerging weapon systems, systems engineering techniques and algorithms, platform level analysis capabilities, integrated platform analysis capabilities, missions thread visualizations capabilities, and related research topics · DD5: Modeling and simulation research and development including: innovative Model-Based Systems Engineering (MBSE) methods and tools, methods for aggregating data across higher and lower-level simulations, and tools for approaches for linking simulation results with mission effectiveness · DD6: Research on Radar unitization in a marine Environment to include component development, power density, advanced signal processing, track processing, and related topics for surface radar applications · DD7: Railgun developmental research including: materials for rail ablation reduction, energy storage, weight reduction, energy recovery, component development, high energy systems components, advanced cooling techniques and related research for railgun systems.

The program supports four main research thrusts that are envisioned to advance the goal of ubiquitous co-robots: scalability, customizability, lowering barriers to entry, and societal impact. Topics addressing scalability include how robots can collaborate effectively with multiple humans or other robots; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments. Customizability includes how to enable co-robots to adapt to specific tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics in lowering barriers to entry include development of open-source co-robot hardware and software, as well as widely-accessible testbeds. Topics in societal impact include fundamental research to establish and infuse robotics into educational curricula, advance the robotics workforce through education pathways, and explore the social, economic, ethical, and legal implications of our future with ubiquitous collaborative robots.

The program supports four main research thrusts that are envisioned to advance the goal of ubiquitous co-robots: scalability, customizability, lowering barriers to entry, and societal impact. Topics addressing scalability include how robots can collaborate effectively with multiple humans or other robots; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments. Customizability includes how to enable co-robots to adapt to specific tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics in lowering barriers to entry include development of open-source co-robot hardware and software, as well as widely-accessible testbeds. Topics in societal impact include fundamental research to establish and infuse robotics into educational curricula, advance the robotics workforce through education pathways, and explore the social, economic, ethical, and legal implications of our future with ubiquitous collaborative robots.

The program supports four main research themes that are envisioned to advance the goal of ubiquitous co-robots:scalability,customizability,lowering barriers to entry, andsocietal impact,includinghuman safety. Topics addressingscalabilityinclude how robots can collaborate effectively with orders of magnitude more humans or other robots than is handled by the current state of the art; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments.Customizabilityincludes how to enable co-robots to adapt to specific different tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics inlowering barriers to entryshould focus on lowering the barriers for conducting fundamental roboticsresearchand research on integrated robotics application. This may include development of open-source co-robot hardware and software, as well as widely-accessible testbeds. Outreach or using robots in educational programs do not, by themselves, lower the barriers to entry for robotics research. Topics insocietal impactinclude fundamental research to establish and infuse robotics into educational curricula, advance the robotics workforce through education pathways, and explore the social, economic, ethical, security, and legal implications of our future with ubiquitous collaborative robots.

The program supports four main research themes that are envisioned to advance the goal of ubiquitous co-robots: scalability, customizability, lowering barriers to entry, and societal impact, including human safety. Topics addressing scalability include how robots can collaborate effectively with orders of magnitude more humans or other robots than is handled by the current state of the art; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments. Customizability includes how to enable co-robots to adapt to specific different tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics in lowering barriers to entry should focus on lowering the barriers for conducting fundamental robotics research and research on integrated robotics application.

A recent report suggests that more than 50 percent of domestic practicing physicians experience burnout. Due to the extremely stressful work environment, patient population, and 24/7 operations with irregular work hours in emergency departments (EDs), ED physicians experience an even higher prevalence of burnout, with up to 65 percent of physicians and residents meeting criteria for burnout. The Reducing Burnout through Emergency Department Design RPF seeks proposals with the potential to reimagine how academic medical center emergency departments are designed by sparking innovation in an environment that has remained largely unchanged for decades. Through the RFP, a single grant of $40,000 will be awarded in support of research that investigates how the design of emergency department environments in academic medical centers impacts physician and resident burnout. Interdisciplinary collaboration is strongly encouraged.

The goal of the Environmental Engineering program is tosupport transformative research which applies scientific and engineering principles to avoid or minimize solid, liquid, and gaseous discharges, resulting from human activities on land, inland and coastal waters, and air, while promoting resource and energy conservation and recovery. The program also fosters cutting-edge scientific research for identifying, evaluating, and monitoring the waste assimilative capacity of the natural Environment and for removing or reducing contaminants from polluted air, water, and soils. Any proposal investigating sensors, materials or devices that does not integrate these products with an Environmental engineering activity or area of research may be returned without review. Major areas of interest include: Enhancing the availability of high quality water supplies: Development of innovative biological, chemical and physical treatment processes to meet the growing demand for water; investigation of processes that remove and degrade contaminants, remediate contaminated soil and groundwater, and convert wastewaters into water suitable for reuse; investigation of Environmental engineering aspects of urban watersheds, reservoirs, estuaries and storm water management; investigation of biogeochemical and transport processes driving water quality in the aquatic and subsurface Environment.