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The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies.

The New York City-based Camille & Henry Dreyfus Foundation is accepting nominations from academic institutions for its Henry Dreyfus Teacher-Scholar Awards Program. The annual program supports the research and teaching careers of talented young faculty in the chemical sciences at undergraduate institutions. Based on institutional nominations, the program provides discretionary funding to faculty at an early stage in their careers. The award is based on accomplishment in scholarly research with undergraduates, as well as a compelling commitment to teaching, and provides an unrestricted research grant of $60,000. The program is open to academic institutions in the states, districts, and territories of the United States that grant a bachelor's or master's degree in the chemical sciences, including biochemistry, materials chemistry, and chemical engineering. Nominees must hold a full-time tenure-track academic appointment; be after the fourth and not after the twelfth years of their independent academic careers; and be engaged in research and teaching primarily with undergraduates.

Eligible applicants are postdoctoral fellows and faculty at degree-granting institutes in the United States or Canada. Applicants must hold a Ph.D. in mathematics, physics, chemistry, computer science, statistics, or engineering and be interested in investigating research opportunities in the biological sciences. Biologists holding a doctorate degree at the time of application who are interested in working with physical scientists, mathematicians, engineers, chemists, statisticians, or computer scientists to incorporate their ideas and approaches to answering biological questions are eligible to apply.

Successful projects will address at least one of ARPA-E?s two Mission Areas: 1. Enhance the economic and energy security of the United States through the development of energy technologies that result in: a. reductions of imports of energy from foreign sources; b. reductions of energy-related emissions, including greenhouse gases; and c. improvement in the energy efficiency of all economic sectors; and 2. Ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies. This program seeks to fund the development of transformational electrochemical energy storage technologies that will accelerate widespread electric vehicle adoption by dramatically improving their driving range, cost, and reliability. To achieve this long-term objective, this program aims to maximize specific energy and minimize cost of energy storage systems at the vehicle level. Central to this system-level approach is the use of robust design principles for energy storage systems. Robust design is defined as electrochemical energy storage chemistries and/or architectures (i.e. physical designs) that avoid thermal runaway and are immune to catastrophic failure regardless of manufacturing quality or abuse conditions. In addition, this program seeks multifunctional energy storage designs that use these robust storage systems to simultaneously serve other functions on a vehicle (for example, in the frame, body, and/or crumple zone), thus further reducing an energy storage syst em?s effective weight when normalized to the entire electric vehicle weight.

EPA-ORD seeks applications from eligible entities to enter into a cooperative agreement with EPA that will provide training opportunities for undergraduate and graduate students on-site at ORD's Ground Water and Ecosystems Research Division (GWERD) research facilities located in Ada, Oklahoma.  It is envisioned that the training program will increase both the effectiveness and number of future environmental scientists. The training received under the mentorship of EPA scientists will complement the trainees' academic coursework. The recipient will be responsible for ensuring that the training projects are supportive of the trainees' academic training.  Some appropriate fields of study for trainees include, but are not limited to, environmental science, water policy, chemistry, engineering, computer science, ecology, and physical and biological sciences.

The U.S. Environmental Protection Agency (EPA), through its Science to Achieve Results (STAR) program, seeks applications for research on how pollution affects human health in the context of the total environment - built, natural, and social environments interacting together with inherent characteristics and interactions. Proposed research should develop and test innovative models or impact assessment approaches to examine causal relationships of chemical pollutants and health effects with modifying interactions among the variables representing all of the major stressors and factors involved in a person's life. Proposals that integrate a diverse field of disciplines (social science, economics, epidemiology, engineering, environmental science, biology, statistics, toxicology, chemistry, etc.) to address the complexity of the total environment research problem are highly recommended.

The SD2 program aims to develop data-driven methods to accelerate scientific discovery and robust design in domains that lack complete models. Engineers regularly use high-fidelity simulations to create robust designs in complex domains such as aeronautics, automobiles, and integrated circuits. In contrast, robust design remains elusive in domains such as synthetic biology, neuro-computation, cyber, and polymer chemistry due to the lack of high-fidelity models. SD2 will develop tools to enable robust design despite the lack of complete scientific models.

Fundamental research topics of interest in SusChEM include the replacement of rare, expensive, and/or toxic chemicals/materials with earth-abundant, inexpensive, and benign chemicals/materials; recycling of chemicals/materials that cannot be replaced; development of non-petroleum based sources of important raw materials; the elimination of waste products and enhancement in efficiencies of chemical reactions and processes; discovery of new separation science that will facilitate recycling and production of valuable chemicals/materials; and development and characterization of low cost, sustainable and scalable-manufactured materials with improved properties.

Examples of fundamental research topics of interest in SusChEM include the replacement of rare, expensive, and/or toxic chemicals/materials with earth-abundant, inexpensive, and benign chemicals/materials; recycling of chemicals/materials that cannot be replaced; development of non-petroleum based sources of important raw materials; chemicals/materials for food and/or water sustainability; the elimination of waste products and enhancement in efficiencies of chemical reactions and processes; discovery of new separation science that will facilitate recycling and production of valuable chemicals/materials; and development and characterization of low cost, sustainable and scalable-manufactured materials with improved properties.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to lead basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the companion PA-18-395.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA (xxxx).

The HVSI funds and performs a range of hypersonic research tasks in support of the Department of Defense (DoD) High Performance Computing Modernization Program (HPCMP). HPCMP desires to improve computational simulations of hypersonic vehicles in support of DoD goals by accelerating the successful development of HPC software and hardware. The HVSI will be looking to improve computational simulation approaches including numerical methods, modeling approaches, and simulation of a variety of aerothermodynamic and propulsion aspects of hypersonic flight. Specific science and technology areas include turbulence, boundary layer transition, fluid-structure-thermal interactions, non-equilibrium chemistry, ablation, and combustion.

The Quantum Idea Incubator for Transformational Advances in Quantum Systems (QII - TAQS) program is designed to support interdisciplinary teams that will explore highly innovative, original, and potentially transformative ideas for developing and applying quantum science, quantum computing, and quantum engineering. Proposals with the potential to deliver new concepts, new platforms, and/or new approaches that will accelerate the science, computing, and engineering of quantum technologies are encouraged. Breakthroughs in quantum sensing, quantum communications, quantum simulations, or quantum computing systems are anticipated. This Quantum Idea Incubator solicitation aims to support the process of translating such ideas into reality. This solicitation calls for proposals focused on interdisciplinary research that includes elements from the following thrust areas: (i) fundamental science such as, but not limited to, physics, chemistry, materials science, mathematics, biology, or geoscience, as well as foundational concepts and techniques in quantum information science and engineering; (ii) communication, computation, and modeling; and (iii) devices and engineered systems. Proposals must articulate how the project leverages and/or promotes advances in knowledge in the selected thrust areas.

In celebrating its 350th anniversary, Merck KGaA, Darmstadt, Germany offers a series of research grants to stimulate innovative research in challenging areas of future importance. Merck KGaA, Darmstadt, Germany intends to provide several research grants of up to EUR 350,000 per year for 3 years in various research areas with the option of extension or expansion. Grants are offered for research in the following areas: Healthy Lives / Drug Discovery: Challenge 1: What is the next game-changing molecule or technology to help cure cancer or autoimmune disease? Life Reimagined / Synthetic Biology: Challenge 1: What is the next generation production technology for biologics? Challenge 2: Can you revolutionize microbiome research? Materials & Solutions: Challenge 1: Can you develop a new generation of intelligent materials? Challenge 2: Can you develop advances in characterization, control and surface chemistry? Challenge 3: Can you develop better atomic layer processes - from modelling to materials? Digitalization / Computing: Challenge 1: How can in-silico research benefit from deep learning or quantum computing?

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and protected time for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. Prospective candidates are encouraged to contact the relevant NIH staff for IC-specific programmatic and budgetary information: Table of IC-Specific Information, Requirements and Staff Contacts.

ACS PRF research grant programs support fundamental research in the petroleum field, and development of the next generation of engineers and scientists through advanced scientific education. Research areas supported include chemistry, the earth sciences, chemical and petroleum engineering, and related fields such as polymers and materials science. Membership in the American Chemical Society is not a requirement or a factor in awarding ACS PRF grants.

The Environmental Engineering program is part of the Environmental Engineering and Sustainability cluster together with 1) the Biological and Environmental Interactions of Nanoscale Materials program and 2) the Environmental Sustainability program. Environmental engineering is an interdisciplinary field that applies chemical, biological, and physical scientific principles to protect human and ecological health. The goal of the Environmental Engineering program is tosupport potentially transformative fundamental research that applies scientific and engineering principles to 1) prevent or minimize solid, liquid, and gaseous discharges of pollution to soil, water, and air; 2) mitigate the ecological and human-health impacts of such releases by smart/adaptive/reactive amendments or manipulation of the environment, and 3) remediate polluted environments through engineered chemical, biological, and/or geo-physical processes. Integral to achieving these goals is a fundamental understanding of the transport and biogeochemical reactivity of pollutants in the environment. Therefore, research on environmental micro/biology, environmental chemistry, and environmental geophysics may be relevant providing there is a clear connection to the application of environmental engineering to protect human and ecological health.

The Electrochemical Systems program is part of the Chemical Process Systems cluster, which also includes: 1) the Catalysis program; 2) the Interfacial Engineering program; and 3) the Process Systems, Reaction Engineering, and Molecular Thermodynamics program. The goal of the Electrochemical Systems program is to support fundamental engineering research that will enable innovative processes involving electro- or photochemistry for the sustainable production of electricity, fuels, and chemicals. Processes for sustainable energy and chemical production must be scalable, environmentally benign, reduce greenhouse gas production, and utilize renewable resources. Research projects that stress fundamental understanding of phenomena that directly impact key barriers to improved system or component-level performance (for example, energy efficiency, product yield, process intensification) are encouraged. Processes for energy storage should address fundamental research barriers for the applications of renewable electricity storage or for transport propulsion. For projects concerning energy storage materials, proposals should involve hypotheses that involve device or component performance characteristics that are tied to fundamental understanding of transport, kinetics, or thermodynamics. Advanced chemistries are encouraged. Proposed research should be inspired by the need for economic and impactful conversion processes. All proposal project descriptions should address how the proposed work, if successful, will improve process realization and economic feasibility and compare the proposed work against current state of the art. Highly integrated multidisciplinary projects are encouraged.

OBJECTIVE: This is an AF Special Topic partnership, please see the above AF Special Topic instructions for further details. A Phase I award will be completed over 3 months with a maximum award of $25K and a Phase II may be awarded for a maximum period of 12 months DESCRIPTION: Academia is producing disruptive science and technology innovations at an increasingly rapid pace. Hence, rather than utilizing a pre-defined requirements approach, this topic is intended to be an open call for ideas and technologies that may not be currently listed (i.e. the unknown-unknown) under STTR topics, but nonetheless still fit within broad interest areas of the Air Force basic research level. These broad areas (Engineering and Complex Systems, Information and Networks, Physical Sciences, and Chemistry/Biological Sciences) are covered in greater detail at wpafb.af.mil/Welcome/Fact-Sheets/Display/Article/842026. To be eligible, offeror(s) must be teams that have formed companies and partnered with a university (e.g. university entrepreneurship centers, university technology transfer offices). The offeror should demonstrate their technical capability by demonstrating a credible and high-potential minimum viable product (MVP) along with a credible plan for developing the prototype to a commercially available solution. This topic is not looking for fully formed products, and it is acceptable if the solutions are earlier stage.

The National Science Foundation (NSF) Directorates for Engineering (ENG) and Geosciences (GEO), the Divisions of Integrative Organismal Systems (IOS) and Environmental Biology (DEB), in the Directorate for Biological Sciences (BIO), the Division of Computer and Network Systems in the Directorate Computer and Information Science and Engineering (CISE/CNS), and the Division of Chemistry (CHE) in the Directorate for Mathematical and Physical Sciences, in collaboration with the US Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) encourage convergent research that transforms existing capabilities in understanding dynamic soil processes, including soil formation, through advances in sensor systems and modeling. The Signals in the Soil (SitS) program fosters collaboration among the two partner agencies and the researchers they support by combining resources and funding for the most innovative and high-impact projects that address their respective missions. To make transformative advances in our understanding of soils, multiple disciplines must converge to produce environmentally-benign novel sensing systems with multiple modalities that can adapt to different environments and collect and transmit data for a wide range of biological, chemical, and physical parameters. Effective integration of sensor data will be key for achieving a better understanding of signaling interactions among plants, animals, microbes, the soil matrix, and aqueous and gaseous components. New sensor networks have the potential to inform models in novel ways, to radically change how data is obtained from various natural and managed (both urban and rural) ecosystems, and to better inform the communities that directly rely on soils for sustenance and livelihood.