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Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will far exceed the simple embedded systems of today. CPS technology will transform the way people interact with engineered systems -- just as the Internet has transformed the way people interact with information. New smart CPS will drive innovation and competition in sectors such as agriculture, energy, transportation, building design and automation, healthcare, and manufacturing. The December 2010 report of the President's Council of Advisors on Science and Technology (PCAST) titled Designing a Digital Future: Federally Funded Research and Development in Networking and Information Technologycalls for continued investment in CPS research because of its scientific and technological importance as well as its potential impact on grand challenges in a number of sectors critical to U.S. security and competitiveness such as the ones noted above. These challenges and technology gaps are further described in aCPS Vision Statementpublished in 2012 by the federal Networking and Information Technology Research and Development (NITRD) CPS Senior Steering Group. Tremendous progress has been made in advancing CPS technology over the last five-plus years. We have explored foundational technologies that have spanned an ever-growing set of application domains, enabling breakthrough achievements in many of these fields. At the same time, the demand for innovation in these domains continues to grow, and is driving the need to accelerate fundamental research to

Through the Cyberlearning: Transforming Education program, NSF seeks to integrate advances in technology with advances in what is known about how people learn to better understand how people learn with technology and how technology can be used productively to help people learn, through individual use and/or through collaborations mediated by technology; better use technology for collecting, analyzing, sharing, and managing data to shed light on learning, promoting learning, and designing learning environments; and design new technologies for these purposes, and advance understanding of how to use those technologies and integrate them into learning environments so that their potential is fulfilled. Of particular interest are technological advances that allow more personalized learning experiences, draw in and promote learning among those in populations not served well by current educational practices, allow access to learning resources anytime and anywhere, and provide new ways of assessing capabilities. It is expected that Cyberlearning research will shed light on how technology can enable new forms of educational practice and that broad implementation of its findings will result in a more actively-engaged and productive citizenry and workforce.

The objective of the Integrated Demonstration and Applications Laboratory (IDAL) Research Program (IDARP) is to conduct leading-edge system of systems spectrum warfare applications/advanced technology development. Research will be conducted utilizing a multispectral synthetic battlespace simulation to integrate sensor/EW technologies, identify/resolve technology issues/risks, demonstrate technology applications/benefits and perform rapid technology insertions/transitions.

The objective of the Integrated Demonstration and Applications Laboratory (IDAL) Research Program (IDARP) is to conduct leading-edge system of systems spectrum warfare applications/advanced technology development. Research will be conducted utilizing a multispectral synthetic battlespace simulation to integrate sensor/EW technologies, identify/resolve technology issues/risks, demonstrate technology applications/benefits and perform rapid technology insertions/transitions.

The Small Business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The topics, listed below, are detailed on the SBIR/STTR topics homepage: Educational Technologies and Applications (EA) Information and Communication Technologies (IC) Semiconductors (S) and Photonic (PH) Devices and Materials Electronic Hardware, Robotics and Wireless Technologies (EW) Advanced Manufacturing and Nanotechnology (MN) Advanced Materials and Instrumentation (MI) Chemical and Environmental Technologies (CT) Biological Technologies (BT) Smart Health (SH) and Biomedical (BM) Technologies

The advancement of sensing technology such as RGBD (Red Green Blue Depth), multi-camera and light field imaging systems, networks of sensors, advanced visual analytics and cloud computing will challenge the longstanding paradigms of capturing, creating, analyzing and utilizing visual information. Advances in Visual and Experiential Computing (VEC) will enable capability, adaptability, scalability, and usability that will far exceed the simple information systems of today. VEC technology will transform the way people interact with visual information through, for example, the realization of new mobile and wearable devices and the emergence of autonomous machines and semantically aware spaces. VEC research will drive innovation and competition in many industrial sectors as well as enhance the quality of life for ordinary people. Fast growing visual data has become a bottleneck in human decision processes in several emergent situations. New VEC technology is crucial to extracting information from complex visual and related data sets, combining this information with intuitive modes of human perception, and generating actionable information. The goal of this joint solicitation between NSF and Intel is to foster novel, transformative, multidisciplinary approaches that promote research in VEC technologies, taking into consideration the various challenges present in this field. This solicitation aims to foster a research community committed to advancing research and education at the confluence of VEC technologies, and to transitioning its findings into practice. NSF and Intel will support three types of projects, each three years in duration: Small projects with funding from $500,000 to $1,000,000 per project; Medium projects with funding from $1,000,001 to $2,000,000 per project; and Large projects with funding from $2,000,001 to $3,000,000.?? It is intended that NSF and Intel will cofund each project in equal amounts. This NSF/Intel partnership combines CISE??s experience

This funding opportunity announcement (FOA) encourages grant applications for national Biomedical Technology Research Resources (BTRR). These Resources conduct research and development of new or improved technologies driven by the needs of basic, translational, and clinical researchers. The Resources are charged to make their technologies available to the research community in a sustainable manner, to provide user training, and to disseminate the Resources technologies and experimental results. Resources should be at the leading edge of their field with respect to both technology development and engagement of the relevant research community. New applicants are strongly encouraged to submit a pre-application in response to PAR-17-315 The pre-application process provides feedback on whether the proposed technology development is appropriate for the NIGMS BTRR program, and the potential competitiveness of a full application.

New information technologies can be envisioned that are based on biological principles and that use biomaterials in the fabrication of devices and components; it is anticipated that these information technologies could enable stored data to be retained for more than 100 years and storage capacity to be 1,000 times greater than current capabilities. These could also facilitate compact computers that will operate with substantially lower power than today's computers. Research in support of these goals can have a significant impact on advanced information processing and storage technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, engineering, physics, chemistry, materials science, computer science, and information science that will enable heretofore-unanticipated breakthroughs as well as meet educational goals.

The National Geographic Society is accepting applications for its Participatory Science program, which supports the development or innovative use of data-driven, technology-powered tools that increase the understanding, preservation, and protection of our planet. Applicants should propose tools that support citizen science work, particularly data collection or data analysis, in ways that create learning experience for citizen scientists, including students. Priority will be given to research, education, and technology projects that create and execute new digital applications, transform existing applications and products, or use current technologies to do one or more of the following: teach students and other citizen scientists about the planet using experiential, crowdsourced technology; encourage individuals who engage with these technologies and projects to build the attitudes, skills, and knowledge necessary to become stewards of the planet and contribute to solving real-world issues; and generate data and/or develop open-source technologies that contribute to scientific inquiry and advance our understanding of the planet.

Amendment 2 to the NASA ARMD Research Opportunities in Aeronautics - 2018 (ROA-2018) NRA has been posted on the NSPIRES site. Research proposals are sought in seven subtopic areas for Appendix D.2 in support of Transformational Tools and Technologies (TTT). The Transformational Tools and Technologies (TTT) Project advances state-of-the-art computational and experimental tools and technologies that are vital to aviation applications in the six strategic thrusts. The project develops new computer-based tools, computational fluid dynamics models, and associated scientific knowledge that will provide first-of-a-kind capabilities to analyze, understand, and predict aviation concept performance. These revolutionary tools will be applied to accelerate NASA's research and the community's design and introduction of advanced concepts. The Project also explores technologies that are broadly critical to advancing ARMD strategic outcomes. Such technologies include the understanding of new types of strong and lightweight materials, innovative controls techniques, and experimental methods. TTT also develops improved Multi-Disciplinary Design, Analysis, & Optimization (MDAO) and systems analysis tools to enable multi-disciplinary integration. All of these technologies will support and enable concept development and benefits assessment across multiple ARMD programs and disciplines. NOIs are due April 16, 2018 and Proposals are due May 14, 2018

Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain. This FOA is intended for the iterative refinement of emergent technologies and approaches that have already demonstrated their transformative potential through initial proof-of-concept testing, and are appropriate for accelerated development of hardware and software while scaling manufacturing techniques towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience practice. Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Applications are expected to integrate appropriate domains of expertise, including where appropriate biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

On the occasion of its 350th anniversary, Merck KGaA, Darmstadt, Germany will fund innovative projects in applied biophysical & analytical research. Projects will be based on the following challenges: · Challenge 1: Analytical technologies for antibodies and antibody-drug conjugates, as well as technologies to determine drug target engagement, or the level of protein or nucleic acid or metabolic biomarkers. · Challenge 2: Analytical technologies for display materials or semiconductors (Liquid Crystals, OLED Materials, Quantum Materials, Reactive Mesogens, Photoresist Materials). E.g. Spectroscopic Methods, MS Hyphenation, Capillary Chromatography and Comprehensive Separation Technologies; Surface analytics for displays (non- or destructive), Sample preparation techniques for ultra-sensitive investigations · Challenge 3: Analytical technologies for the characterization of polymers, chemical imaging, bioanalytical methods or new methods in molecular biology. Technologies of interest for example are: field flow floractionation (FFF), dynamic light scattering (DLS), chemical imaging, new chromatographic techniques, spectroscopic and spectrometric methods, electron paramagnetic resonance (EPR), microwave analytics

The STMD Small Spacecraft Technology program seek proposals from accredited U.S. universities to develop unique, disruptive, or transformational space technologies that have the potential to enable mission capabilities that are more rapid, more transformative, and more affordable than previously achievable. The overall objective of the Small Spacecraft Technology program is to facilitate development projects and demonstration missions that: enable new mission architectures for which small spacecraft are uniquely suited; expand the capability of small spacecraft to execute missions at new destinations and in challenging new environments; enable the augmentation of existing assets and future missions with supporting small spacecraft. The appendix exclusively seeks proposals that are responsive to one of three topics: (1) Instrument Technologies for Small Spacecraft. (2) Technologies That Enable Large Swarms of Small Spacecraft. (3) Technologies That Enable Deep Space Small Spacecraft Missions. Only accredited U.S. universities are eligible to submit proposals.

Future ultra-low-energy computing, storage and signal-processing systems can be built on principles derived from organic systems that are at the intersection of chemistry, biology, and engineering. New information technologies can be envisioned that are based on biological principles and that use biomaterials in the fabrication of devices and components; it is anticipated that these information technologies could enable stored data to be retained for more than 100 years and storage capacity to be 1,000 times greater than current capabilities. These could also facilitate compact computers that will operate with substantially lower power than today's computers. Research in support of these goals can have a significant impact on advanced information processing and storage technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, engineering, physics, chemistry, materials science, computer science, and information science that will enable heretofore-unanticipated breakthroughs as well as meet educational goals.

An initiative of the Open Technology Fund, the Internet Freedom Fund strives to build the capacity of individuals, organizations, and companies working to advance technology-centered efforts designed to strengthen Internet freedom and promote human rights by circumventing repressive censorship and surveillance, improving related digital security capabilities, and contributing to the overall health of the Internet. To that end, ITF invites applications focused on creating new open source circumvention technologies that fill a current need of target users; improve the security, usability, and adaptability of existing open source Internet freedom technologies; and/or provide new or deeper insight into the challenges of front-line communities that ultimately contribute to the improvement of technological solutions .The fund also supports applied research; research that focuses on real-time monitoring and analysis of both technical and political threats to Internet freedom; new content redistribution methods able to reintroduce content behind firewalls; and next-generation tools that move beyond traditional "cat-and-mouse" circumvention techniques.

Generating Electricity Managed by Intelligent Nuclear Assets(GEMINA) Agency Overview: The Advanced Research Projects Agency - Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358) to: "(A) to enhance the economic and energy security of the United States through the development of energy technologies that result in- (i) reductions of imports of energy from foreign sources; (ii) reductions of energy-related emissions, including greenhouse gases; and (iii) improvement in the energy efficiency of all economic sectors; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies." ARPA-E issues this Funding Opportunity Announcement (FOA) under the programmatic authorizing statute codified at 42 U.S.C. § 16538. The FOA and any awards made under this FOA are subject to 2 C.F.R. Part 200 as amended by 2 C.F.R. Part 910. ARPA-E funds research on and the development of high-potential, high-impact energy technologies that are too early for private-sector investment. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. Program Overview: The aim of this ARPA-E program is to make a transformational change to the current state-of-the-art and improve advanced reactor (AR) designs with operations and maintenance (O&M) in mind.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II).  Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering.  Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies.  Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II). Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering. Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies. Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

This announcement encourages pre-applications for the creation of national Biomedical Technology Research Resources (BTRRs). These Resources develop new or improved technology driven by the needs of basic, translational, and clinical researchers. The BTRRs are charged to make their technologies available to the biomedical research community, to train members of this community in the use of the technologies, and to disseminate both the technologies and the Resources experimental results broadly.

This Funding Opportunity Announcement (FOA) encourages grant applications for Biomedical Technology Resource Centers (BTRCs). BTRCs are national resource centers for conducting research and development on new technologies that are driven by the needs of basic, translational, and/or clinical researchers. BTRCs also make their technologies available to other investigators, train members of the research community in the use of the technologies, and disseminate the technologies broadly.

The Division of Computer and Network Systems (CNS) within the National Science Foundation's (NSF) Directorate for Computer and Information Science and Engineering (CISE) supports research and education activities that seek to develop a better understanding of the fundamental properties of computer and network systems. The Networking Technology and Systems (NeTS) program in the CNS division supports transformative research on fundamental scientific and technological advances leading to the development of Next Generation Internet (NGI) and Advanced Wireless Networking (AWN) systems and technologies. NSF/CISE and the European Commission's (EC) Directorate General for Communication Networks, Content and Technology (DG CONNECT) seek to enable US and European Union (EU) researchers to collaborate to address compelling research challenges in NGI and AWN. Topics of interest include, but are not limited to, software-defined infrastructures; network function virtualization; resource management in support of content delivery; open data architectures for shared, federated research infrastructures; advanced wireless technologies; and research software tools to support advanced wireless and smart city/community testbeds.