NineSights Community - Request for Proposal: 2aTechnologies to deliver poorly membrane-permeable peptides 2c - 0 views
-
MiamiOH OARS on 08 Jan 19Target poorly membrane-permeable peptides Molecular weight: Approx. 500-2000 Technology requirements The Client seeks either one of the following types of technologies: (1) A formulation / DDS technology to deliver poorly membrane-permeable peptides into target cells Target sites / diseases: Not specified * Excludes technologies that are applicable only to cancer cells Routes of administration: Oral, intravenous, subcutaneous and intramuscular injections (delivered through blood vessels into target cells), transnasal (delivered from olfactory bulbs into brain tissues), transpulmonary (delivered into / retained in lung cells, for lung diseases), etc. (2) A formulation / DDS technology to enhance gastrointestinal absorption of poorly membrane-permeable peptides with both of para- and trans-cellular routes.