Group items tagged

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) solicits research proposals to address significant challenges in Fetal Alcohol Spectrum Disorders (FASD) research in the areas of diagnosis/screening, etiology, interventions and treatment. Cooperative Agreement (UH2) applications in response to this FOA should propose exploratory/developmental projects, based on new and innovative concepts, approaches, and technologies. This solicitation is open to all. To maximize the impact of their research, awardees will be encouraged to establish a collaborative relationship with the NIAAA-supported Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) consortium.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research that would develop and validate new screening methods for autism spectrum disorders (ASD) that can be used in infancy (0-12 months of age). This FOA uses the R21 grant mechanism, while RFA- MH-19-120 uses the R01 grant mechanism. Applications with strong preliminary data proposing validation, refinement or final stages of testing of existing tools or methods may be more appropriate for the R01 mechanism. Pilot or exploratory projects with minimal preliminary data, or those proposing early-stage feasibility testing, may be more appropriate for this FOA (R21 mechanism).

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research grant applications to support research designed to elucidate the etiology, epidemiology, diagnosis, treatment, and optimal means of service delivery in relation to Autism Spectrum Disorders (ASD). 

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research to develop and validate new screening methods for autism spectrum disorders (ASD) that can be used in infancy (0-12 months of age). This FOA uses the R01 grant mechanism, while RFA-MH-19-121 uses the R21 grant mechanism. Pilot or exploratory projects with minimal preliminary data, or those proposing early-stage feasibility testing, may be most appropriate for the R21 mechanism. Applicants with strong preliminary data proposing validation, refinement or final stages of testing of existing tools or methods may wish to use this FOA (R01 mechanism).

This Funding Opportunity Announcement (FOA) invites applications that propose to develop and implement early stage (Phase I or II) clinical trials of promising pharmacological and non-pharmacological interventions in individuals with age-related cognitive decline and in individuals with Alzheimer's disease (AD) across the spectrum from pre-symptomatic to more severe stages of disease, as well as to stimulate studies to enhance trial design and methods.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), the Division of Epidemiology, Statistics, and Prevention Research intends to solicit proposals to award an Indefinite Delivery Indefinite Quantity (IDIQ) contract to an organization to conduct various studies focusing on a spectrum of health effects in men, women, and children that rely on quantification of analytes in biological specimens such as blood, urine, adipose tissue, follicular fluids, and seminal fluids.  The Division needs a variety of banked specimens analyzed for concentrations of various hormone levels, dietary biomarkers, and indicators of metabolic function among other analytes.

This Funding Opportunity Announcement (FOA) seeks to stimulate innovative research that will increase our understanding of the role that uncultivable bacterial species play in the microbial ecology of the human oral microbiota during states of health and disease. The effective integration of current technologies and the development of new tools and innovative methods are especially encouraged.Due to the wide spectrum of possible experimental approaches and the multidisciplinary tools that will be required to study this unique microbial population, this FOA is designed specifically to encourage team science that will leverage innovation, broad expertise and multiple technological platforms to answer hypothesis-driven questions regarding these bacteria.Consistent with this approach, the use of a multiple Program Directors/Principal Investigators (PDs/PIs) model is encouraged that will recruit complementary and collaborative research teams to conduct these studies.

This Funding Opportunity Announcement (FOA) seeks to stimulate innovative research that will increase our understanding of the role that uncultivable bacterial species play in the microbial ecology of the human oral microbiota during states of health and disease. The effective integration of current technologies and the development of new tools and innovative methods are especially encouraged.  Due to the wide spectrum of possible experimental approaches and the multidisciplinary tools that will be required to study this unique microbial population, this FOA is designed specifically to encourage team science that will leverage innovation, broad expertise and multiple technological platforms to answer hypothesis-driven questions regarding these bacteria.  Consistent with this approach, the use of a multiple Program Directors/Principal Investigators (PDs/PIs) model is encouraged that will recruit complementary and collaborative research teams to conduct these studies.  

The Geobiology and Low-Temperature Geochemistry Program supports research on 1) the interactions between biological and geological systems at all scales of space and time; 2) geomicrobiology and biomineralization processes; 3) the role of life in the transformation and evolution of the Earth's geochemical cycles; 4) inorganic and organic geochemical processes occurring at or near the Earth's surface now and in the past, and at the broad spectrum of interfaces ranging in scale from planetary and regional to mineral-surface and supramolecular; 5) mineralogy and chemistry of soils and sediments; 6) surficial chemical and biogeochemical systems and cycles and their modification through natural and anthropogenic change; and 7) development of tools, methods, and models for low-temperature geochemistry and geobiological research - such as those emerging from molecular biology - in the study of the terrestrial environment.

The MID-ARA Focus Areas are: * Development of new methods for rapid multi-pathogen/multi-phenotype detection of multidrug-resistant organisms (MDROs), nosocomial pathogens, and/or rapid multi-pathogen/multi-phenotype characterization of antimicrobial resistance patterns. * Development of assays for host immune response biomarkers for diagnosis or prognosis of infection to inform clinical wound management decisions * Development and preclinical testing of novel chemotypes, biologics as potential therapeutics or prophylactics for wound infection, and/or biofilm formation, maintenance, or propagation. Innovative treatment approaches are encouraged. NOTES FOR ALL FOCUS AREAS: * Preference will be given to approaches that address infections with one or more MDROs, particularly, Acinetobacter baumannii, Pseudomonas aeruginosa, extended-spectrum beta-lactamase producing Enterobacteriaceae, and methicillin-resistant Staphylococcus aureus (MRSA), and/or invasive fungal (mold) pathogens. * Preference will be given to studies leading toward topical treatments for prevention and management of wound infection. Overview: The FY14 DMRDP MID-ARA seeks applied research applications focused on the reduction of combat-related or trauma-induced wound infection morbidity and mortality. 

The PRP Impact Award mechanism is being offered for the first time in FY16.The Impact Award encourages applications that support the full spectrum of research projects or ideas that specifically focus on scientific and clinical Parkinson's disease issues, which, if successfully addressed, have the potential to make a major impact in preventing or halting the progression of Parkinson's disease or enhancing the well-being of individuals experiencing the impact of the disease

This announcement solicits applications for two (2) separate competitions, HRSA-17-013 Autism Field-Initiated Innovative Research Studies and HRSA-17-014 Autism Longitudinal Data Project.  The purpose of the Autism Field-Initiated Innovative Research Studies and the Autism Longitudinal Data Project competitions are to support the conduct of empirical research that advances the evidence base on interventions to improve the health and wellbeing of children and adolescents with autism spectrum disorders (ASD), with a special focus on addressing the needs of underserved populations.  These competitions will address the critical need that exists for research on the barriers to screening, diagnosis, and receipt of evidence-based interventions.

The purpose of this FOA is to seek out, identify and support bold and innovative approaches designed to broaden graduate and postdoctoral training, such that training programs reflect the range of career options that Ph.D. graduate students and postdoctoral (regardless of funding source) pursue and that are required for a robust biomedical, behavioral, social and clinical research enterprise. Collaborations with non-academic partners are encouraged to ensure that experts from a broad spectrum of research-intensive and research-related careers contribute to coursework, rotations, internships or other forms of exposure. This program will establish a new paradigm for graduate and postdoctoral training; awardee institutions will work together to define needs and share best practices.

In 2013, a new NSF-funded petascale computing system, Blue Waters, was deployed at the University of Illinois.  The goal of this project and system is to open up new possibilities in science and engineering by providing computational capability that makes it possible for investigators to tackle much larger and more complex research challenges across a wide spectrum of domains.  The purpose of this solicitation is to invite research groups to submit requests for allocations of resources on the Blue Waters system. Proposers must show a compelling science or engineering challenge that will require petascale computing resources. Proposers must also be prepared to demonstrate that they have a science or engineering research problem that requires and can effectively exploit the petascale computing  capabilities offered by Blue Waters.  Proposals from or including junior researchers are encouraged, as one of the goals of this solicitation is to build a community capable of using petascale computing.

This NASA Research Announcement (NRA) solicits hypothesis-driven space-flight research in Space Biology (SB) to be conducted on ISS. NASA SB experiments have one or more of the following primary goals: 1) to effectively use microgravity and the other characteristics of the space environment to enhance our understanding of basic biological processes; 2) to develop the scientific and technological foundations for a safe, productive human presence in space for extended periods and in preparation for exploration; and 3) to apply this knowledge and technology to improve our nation's competitiveness, education, and the quality of life on Earth. NASA SB experiments will be designed to discover how space flight affects a diverse group of microorganisms, plants, and animals; study the effects of gravity (g) across the g-spectrum, i.e., from micro- to hyper-gravity; and characterize the biological effects of radiation, magnetic fields, and the interaction among species i n the unusual environments of space and spacecraft. 

This award program is designed to enhance our existing support of autism research by providing timely resources to enable focused experiments highly relevant to our mission. A deeper understanding of the mechanisms underlying autism spectrum disorders or potential therapeutic approaches will require investigation at multiple levels, including but not limited to studies focused on gene discovery, molecular mechanisms, circuits, anatomy, and cognition and behavior. We will consider proposals at all of these levels. The maximum budget is $60,000, including indirect costs for one (1) year, non-renewable. Explorer Awards are intended to provide resources to support exploratory experiments that will strengthen hypotheses and lead to the formulation of competitive applications for subsequent larger-scale funding by SFARI or other organizations. Innovative, high-risk/high-impact proposals are encouraged. We especially encourage applications from investigators who are new to the field of autism, but who have expertise that could be brought to bear on this complex disorder.

The Foundation accepts applications for grants to conduct research on the effects of alcohol consumption on health and behavior. The following areas are of greater interest: Studies on how particular patterns of consumption (quantity of alcohol consumed, types of alcoholic beverages consumed, frequency of consumption and context) are related to health and behavioral outcomes. Interdisciplinary, bio-informatics, and other approaches to elucidate genetic and environmental factors that influence the patterns of consumption of alcoholic beverages and related consequences. The Foundation encourages basic and clinical research, including epidemiology. Examples of research topics include factors influencing underage drinking, mechanisms of alcohol-related organ injury, fetal alcohol spectrum disorders, and effects of alcohol on general health.   The Foundation gives preference to young investigators, but does not support students or trainees in pre- or post-doctoral programs. It does not fund thesis or dissertation research. Grants are made to academic and research institutions in the United States, Canada and South Africa, not to individuals. Evidence of support for the investigator from the institution is desirable. 

PoLS encourages research that emphasizes the physical principles of organization and function of living systems, including the exploration of artificial life forms. While the problems under study must be important to advancing our understanding of the living world in a quantitative way, particular emphasis will be placed on those projects in which lessons learned from the biological application also expand the intellectual range of physics. Awards will cover a broad spectrum of physics approaches in biology, ranging from the physical principles and mechanisms at the single cell level such as cellular organization (e.g. cytoskeleton), energy metabolism, gene regulation and intracellular and intercellular communication, to collective behavior and evolution of complexity in life forms and living populations of organisms. This systems approach in physics has been very successful in understanding inanimate systems, and has the potential to bring deep understanding of the world of animated, replicating systems, through testable phenomenological theories. The program funds individual investigators, although collaborative proposals between physicists and biological researchers are welcome. Proposals with potential societal impact such as renewable energy and human health are good examples of strong broader impact and are of interest to the program.

This NASA Research Announcement (NRA) solicits hypothesis-driven space-flight research in Space Biology (SB) to be conducted on ISS. NASA SB experiments have one or more of the following primary goals: 1) to effectively use microgravity and the other characteristics of the space environment to enhance our understanding of basic biological processes; 2) to develop the scientific and technological foundations for a safe, productive human presence in space for extended periods and in preparation for exploration; and 3) to apply this knowledge and technology to improve our nation's competitiveness, education, and the quality of life on Earth. NASA SB experiments will be designed to discover how space flight affects a diverse group of microorganisms, plants, and animals; study the effects of gravity (g) across the g-spectrum, i.e., from micro- to hyper-gravity; and characterize the biological effects of radiation, magnetic fields, and the interaction among species in the unusual environments of space and spacecraft. 

The purposes of the NCIPC extramural violence prevention research program are to: 1. Build the scientific base for the prevention of violence by helping to expand and advance our understanding of the primary prevention of interpersonal violence. 2. Encourage professionals from a wide spectrum of disciplines of epidemiology, behavioral and social sciences, medicine, biostatistics, public health, health economics, law, and criminal justice to perform research in order to prevent violence more effectively. 3. Encourage investigators to propose research that involves the development and testing of primary prevention strategies, programs and policies designed to prevent interpersonal violence and reduce violence-related outcomes as well as dissemination, implementation, and translation research to enhance the adoption and maintenance of effective strategies among individuals, organizations, or communities.