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Matti Narkia

Docosahexaenoic acid induces proteasome-dependent degradation of {beta}-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2 -- Calviello et al. 28 (6): 1202 -- Carcinogenesis - 0 views

carcin.oxfordjournals.org/...1202

2007 June Carcinogenesis study research in_vitro DHA omega-3 proteasome-dependen proteasome degradation beta-catenin down-regulation survivin apoptosis colorectal cancer cells colorectal_cancer COX-2 nutrition medline MMP-7 VEGF MMP

shared by Matti Narkia on 06 Aug 09 - Cached
  • Matti Narkia on 06 Aug 09
     
    The present study, thus, raises the possibility that DHA may exert pro-apoptotic and antitumoral effects through proteasomal regulation of beta-catenin levels and alterations in the expression of TCF-beta-catenin target genes. Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, Monego G, Ranelletti FO, Palozza P. Carcinogenesis. 2007 Jun;28(6):1202-9. Epub 2006 Dec 20. PMID: 17183061 doi:10.1093/carcin/bgl254
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