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Arachidonate 5-lipoxygenase (5-lipoxygenase, 5-LO, 5-LOX or Alox5), which transforms EFAs into leukotrienes, is a current target for pharmaceutical intervention in a number of diseases. 5-LO is a target for pharmaceutical intervention in CAD.

Mientras que hay muchas formas de perder peso, mantener su pérdida de peso a largo plazo es a menudo muy difícil. Si usted ha subido y bajado de peso varias veces antes, es probable que sea hora de volver a los principios básicos de un peso saludable: Prevención del aumento de peso o dejar de ganar peso reciente puede mejorar su salud.La salud pueden mejorar significativamente con la perdida de peso (5 por ciento a 10 por ciento del peso corporal)

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. [No authors listed] Lancet. 1999 Aug 7;354(9177):447-55. Erratum in: Lancet 2001 Feb 24;357(9256):642. Lancet. 2007 Jan 13;369(9556):106. PMID: 10465168 Interpretation Dietary supplementation with n-3 PUFA led to a clinically important and satistically significant benefit. Vitamin E had no benefit. Its effects on fatal cardiovascular events require further exploration

Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study. Ebbesson SO, Roman MJ, Devereux RB, Kaufman D, Fabsitz RR, Maccluer JW, Dyke B, Laston S, Wenger CR, Comuzzie AG, Romenesko T, Ebbesson LO, Nobmann ED, Howard BV. Atherosclerosis. 2008 Aug;199(2):346-53. Epub 2007 Dec 4. PMID: 18054937 doi:10.1016/j.atherosclerosis.2007.10.020 Conclusions Dietary intake of omega-3 FAs in a moderate-to-high range does not appear to be associated with reduced plaque, but is negatively associated with IMT. The presence and extent of carotid atherosclerosis among Eskimos is higher with increasing consumption of saturated FAs.