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Matti Narkia

Efficacy and safety of berberine for congestive heart failure secondary to ischemic or ... - 1 views

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    Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
    Zeng XH, Zeng XJ, Li YY.
    Am J Cardiol. 2003 Jul 15;92(2):173-6.
    PMID: 12860219
    doi:10.1016/S0002-9149(03)00533-2

    Thus, berberine improved quality of life and decreased VPCs and mortality in patients with CHF.
Matti Narkia

Efficacy of Berberine in Patients with Type 2 Diabetes - 0 views

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    Efficacy of berberine in patients with type 2 diabetes mellitus.
    Yin J, Xing H, Ye J.
    Metabolism. 2008 May;57(5):712-7.
    PMID: 18442638
    doi: 10.1016/j.metabol.2008.01.013.

    Fasting plasma insulin and homeostasis model assessment of insulin resistance index were reduced by 28.1% and 44.7% (P<.001), respectively. Total cholesterol and low-density lipoprotein cholesterol were decreased significantly as well. During the trial, 20 (34.5%) patients experienced transient gastrointestinal adverse effects. Functional liver or kidney damages were not observed for all patients. In conclusion, this pilot study indicates that berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism

    In summary, that berberine is a potent oral hypoglycemic agent with modest effect on lipid metabolism. It is safe and the cost of treatment by berberine is very low. It may serve as a new drug candidate in the treatment of type 2 diabetes. However, this is a pilot study. The efficacy of berberine needs to be tested in a much larger population and characterized as a function of the known duration of the diabetes. Further studies are needed to evaluate the action of berberine on type 2 diabetes in other ethnic groups.
Matti Narkia

A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone... - 0 views

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    A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.
    Gleason CE, Carlsson CM, Barnet JH, Meade SA, Setchell KD, Atwood CS, Johnson SC, Ries ML, Asthana S.
    Age Ageing. 2009 Jan;38(1):86-93. Epub 2008 Dec 2.
    PMID: 19054783
    doi:10.1093/ageing/afn227

    Conclusions: these data suggest that administration of 100 mg/day of isoflavones was well tolerated. Plasma genistein and daidzein levels, but not equol, increased with isoflavone administration. Finally, data support the potential cognitive effects of soy isoflavones in older adults.
Matti Narkia

Vitamin D2 Is as Effective as Vitamin D3 in Maintaining Circulating Concentrations of 2... - 0 views

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    Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D.
    Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD.
    J Clin Endocrinol Metab. 2008 Mar;93(3):677-81. Epub 2007 Dec 18.
    PMID: 18089691

    Conclusion: A 1000 IU dose of vitamin D2 daily was as effective as 1000 IU vitamin D3 in maintaining serum 25-hydroxyvitamin D levels and did not negatively influence serum 25-hydroxyvitamin D3 levels. Therefore, vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status.
Matti Narkia

Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does... - 0 views

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    Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2.
    Trang HM, Cole DE, Rubin LA, Pierratos A, Siu S, Vieth R.
    Am J Clin Nutr. 1998 Oct;68(4):854-8.
    PMID: 9771862

    Although the 1.7-times
    greater efficacy for vitamin D3 shown here may seem small, it is
    more than what others have shown for 25(OH)D increases when
    comparing 2-fold differences in vitamin D3 dose. The
    assumption that vitamins D2 and D3 have equal nutritional value
    is probably wrong and should be reconsidered.
Matti Narkia

Vitamin D2 Is Much Less Effective than Vitamin D3 in Humans -- Armas et al. 89 (11): 53... - 0 views

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    Vitamin D2 is much less effective than vitamin D3 in humans.
    Armas LA, Hollis BW, Heaney RP.
    J Clin Endocrinol Metab. 2004 Nov;89(11):5387-91.
    PMID: 15531486

    Vitamin D2 potency is less than one third that of vitamin D3. Physicians resorting to use of vitamin D2 should be aware of its markedly lower potency and shorter duration of action relative to vitamin D3.
Matti Narkia

eMJA: Annual intramuscular injection of a megadose of cholecalciferol for treatment of ... - 0 views

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    Annual intramuscular injection of a megadose of cholecalciferol for treatment of vitamin D deficiency: efficacy and safety data. Diamond TH, Ho KW, Rohl PG, Meerkin M.
    Med J Aust. 2005 Jul 4;183(1):10-2.
    PMID: 15992330

    Conclusions: Once-yearly intramuscular cholecalciferol injection (600 000 IU) is effective therapy for vitamin D deficiency. While this therapy appears to be safe, the potential for developing hypercalciuria needs to be examined in a large randomised controlled trial.
Matti Narkia

Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect l... - 0 views

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    Vieth R, Chan PC, MacFarlane GD.Efficacy and safety of vitamin D3 intake exceeding the lowest observedadverse effect level.Am J Clin Nutr. 2001 Feb;73(2):288-94.PMID: 11157326 [PubMed - indexed for MEDLINE]
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