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Matti Narkia

Defining Adequate Vitamin D Intake : Cross-sectional and Intervention Studies - 0 views

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    Defining Adequate Vitamin D Intake : Cross-sectional and Intervention Studies
    Viljakainen, Heli Tuulikki
    University of Helsinki
    2008-05-23
    Doctoral dissertation (article-based)

    Vitamin D is required for normal bone growth and maintenance of the skeleton throughout life. In Finland, like in many other Western countries, the population suffers from inadequate or deficient vitamin D status, especially during winter, which is thought to increase the risk of osteoporosis. New strategies to prevent osteoporosis are actively being sought. The main objective of this thesis was to determine whether vitamin D is feasible in the primary prevention of osteoporosis; does it affect bone mineral accrual during the growth period? A second goal was to ascertain whether seasonal variation in calcitropic hormones affects bone remodelling, and to elucidate the vitamin D intake needed to overcome this variation in different age groups.

    In summary, vitamin D intake remains inadequate among the target groups of this thesis, as reflected by seasonal variation in calcitropic hormones and bone metabolism. Dietary intake of vitamin D should be increased to achieve at least an adequate vitamin D status (S-25-OHD>50 nmol/l) and possibly an optimal vitamin D status (S-25-OHD>80 nmol/l) throughout the year. This could be accomplished by introducing new vitamin D-fortified foods to the market."
Matti Narkia

Effect of low dose vitamin K2 (MK-4) supplementation on bio-indices in postmenopausal J... - 0 views

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    Effect of low dose vitamin K2 (MK-4) supplementation on bio-indices in postmenopausal Japanese women.
    Koitaya N, Ezaki J, Nishimuta M, Yamauchi J, Hashizume E, Morishita K, Miyachi M, Sasaki S, Ishimi Y.
    J Nutr Sci Vitaminol (Tokyo). 2009 Feb;55(1):15-21.
    PMID: 19352059

    These results suggest that supplementation with 1.5 mg/d MK-4 accelerated the degree of OC gamma-carboxylation. The concentrations of serum lipids and other indices were not different between the groups at either intervention period. Thus, the additional intake of MK-4 might be beneficial in the maintenance of bone health in postmenopausal Japanese women.
Matti Narkia

Vitamin D deficiency and bone health in healthy adults in Finland: could this be a conc... - 0 views

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    Vitamin D deficiency and bone health in healthy adults in Finland: could this be a concern in other parts of Europe?
    Lamberg-Allardt CJ, Outila TA, Kärkkainen MU, Rita HJ, Valsta LM.
    J Bone Miner Res. 2001 Nov;16(11):2066-73.
    PMID: 11697803

    Low vitamin D status was prevalent in these young adults in northern Europe in winter, although the vitamin D intake met the recommendation. This probably is not a local problem for northern Europe, because the natural sources of vitamin D are scarce and fortification is not very common in Europe, and with the exception of the southern part of Europe, sunshine is not very abundant in this part of the world. Thus, the results of this study indicate that more attention should be focused on vitamin D status and the sources of vitamin D in these countries.
Matti Narkia

Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual a... - 0 views

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    Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial.
    Cheng S, Lyytikäinen A, Kröger H, Lamberg-Allardt C, Alén M, Koistinen A, Wang QJ, Suuriniemi M, Suominen H, Mahonen A, Nicholson PH, Ivaska KK, Korpela R, Ohlsson C, Väänänen KH, Tylavsky F.
    Am J Clin Nutr. 2005 Nov;82(5):1115-26; quiz 1147-8.
    PMID: 16280447
Matti Narkia

The Balance of Bone Health: Tipping the Scales in Favor of Potassium-Rich, Bicarbonate-... - 0 views

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    The balance of bone health: tipping the scales in favor of potassium-rich, bicarbonate-rich foods.
    Lanham-New SA.
    J Nutr. 2008 Jan;138(1):172S-177S. Review.
    PMID: 18156420
Matti Narkia

The Importance of Calcium, Potassium, and Acid-Base Homeostasis in Bone Health and Oste... - 0 views

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    The importance of calcium, potassium, and acid-base homeostasis in bone health and osteoporosis prevention.
    Tylavsky FA, Spence LA, Harkness L.
    J Nutr. 2008 Jan;138(1):164S-165S.
    PMID: 18156418

    In concert with the acid-base literature, protein intake is considered to be a net acid-producing substance and thus a net negative risk factor for bone dissolution. However, substantial literature supports the beneficial effects on skeletal metabolism when higher protein levels are consumed in concert with adequate calcium, potassium, and other minerals, regardless of the source of protein (24-26). The Dietary Approaches to Stopping Hypertension (DASH) diet (27) is a calcium-rich diet that emphasizes fruits, vegetables, and low-fat dairy products. This diet underscores the importance of consuming a complement of foods from meats, grains, dairy, fruits, and vegetables as prudent for promoting optimal bone health. In the following articles, Rafferty and Lanham-New carefully review the evidence on the interaction of specific diet components that impact bone health and conclude that a balanced diet with recommended servings of dairy products and a variety of fruits and vegetables is prudent for optimal bone health. Additionally, they comment on future research directions for consideration by the scientific community.
Matti Narkia

Prevention of Nonvertebral Fractures With Oral Vitamin D and Dose Dependency: A Meta-an... - 0 views

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    Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials.
    Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J.
    Arch Intern Med. 2009 Mar 23;169(6):551-61.
    PMID: 19307517

    Conclusion Nonvertebral fracture prevention with vitamin D is dose dependent, and a higher dose should reduce fractures by at least 20% for individuals aged 65 years or older.
Matti Narkia

Top 20 nutrients for healthy bones - Better Bones - 0 views

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    Depending on how we count them, there are at least 20 bone-building nutrients which are essential for optimal bone health - "essential" in that our bodies cannot manufacture them, so we must get them from our food and drink. Let's take a quick look at them, one by one, so you can get a better idea of their roles in bone health and how much of each you should be getting. Remember, none of these nutrients does its work in isolation - you need some of each and every one, so they can all work together to keep your bones standing strong all your life long.
Matti Narkia

Phytoestrogens and Bone Health - 0 views

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    Many postmenopausal women are looking for alternatives to hormone therapy, especially in light of research findings in 2003 from the Women's Health Initiative. With major funding from the National Institutes of Health, this initiative studied the risks of combined estrogen and progestin therapy, among other health issues of critical importance to postmenopausal women. Of particular interest are phytoestrogens, which have been gaining popularity because they are marketed as "natural," because of the alleged health benefits they provide, and because they are available in a wide range of foods and supplements. This fact sheet provides an overview of phytoestrogens and discusses their potential role in osteoporosis prevention and treatment.
Matti Narkia

Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammat... - 0 views

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    Z. Papoutsi, E. Kassi, I. Chinou, M. Halabalaki, L. A. Skaltsounis and P. Moutsatsou (2008).
    Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483.
    British Journal of Nutrition, 2008 Apr, 99 , pp 715-722
    PMID: 17916277
    doi:10.1017/S0007114507837421
Matti Narkia

Mediterranean Diet Helps Women Preserve Their Bone Mass, Study Suggests - 0 views

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    ScienceDaily (Feb. 26, 2009) - A study from the Harokopio University of Athens (Greece) suggests that adherence to a dietary pattern close to the Mediterranean diet, with high consumption of fish and olive oil and low red meat intake, has a significant impact in women skeletal health.
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