Skip to main content

Home/ Nutrition/ Group items tagged omega-3 review study prevention

Rss Feed Group items tagged

Matti Narkia

Are omega-3 fatty acids options for prevention and treatment of cognitive decline and d... - 0 views

  •  
    Are omega-3 fatty acids options for prevention and treatment of cognitive decline and dementia?
    Cederholm T, Palmblad J.
    Curr Opin Clin Nutr Metab Care. 2009 Dec 16. [Epub ahead of print]
    PMID: 20019606

    PURPOSE OF REVIEW: To report recent data on the potential role of omega-3 fatty acids (n-3 FA) found in oily fish, especially docosahexaenoic acid (DHA), to prevent and treat cognitive decline and Alzheimer's disease. RECENT FINDINGS: Observational studies still provide conflicting results, in which the majority indicate beneficial effects on cognition, both when assessed as a continuous variable or as incident dementia, mainly Alzheimer's disease. Experimental studies have demonstrated potentially ameliorating effects of eicosapentaenoic acid (EPA) and DHA on amyloid fragment formation, signal transduction including upregulation of the apolipoprotein receptor SorLA, as well as on angiogenesis. The role of EPA and DHA metabolites on Alzheimer's disease pathology is under investigation. Recently, three randomized intervention studies, with duration up to 6 months have been reported. In contrast to a small study from Taiwan, no positive overall effects were reported from the Swedish OmegAD Study or from a Dutch study, although post hoc analyses indicate that selected individuals with mild forms of Alzheimer's disease or cognitive decline may respond to treatment. SUMMARY: No firm conclusions can be drawn. Based on epidemiological data, fish including oily fish could be advised as part of a balanced diet for public health purpose, although the evidence for better cognition is only fairly consistent. It is unlikely that n-3 FA will emerge as a treatment option in general for improving cognitive function in patients with Alzheimer's disease. n-3 FA, especially DHA, may turn out as an adjuvant therapy in selected cases. Further long-term intervention studies on individuals with mild cognitive reductions are awaite"
Matti Narkia

Clinical Prevention of Sudden Cardiac Death by n-3 Polyunsaturated Fatty Acids and Mech... - 0 views

  •  
    Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils.
    Leaf A, Kang JX, Xiao YF, Billman GE.
    Circulation. 2003 Jun 3;107(21):2646-52. Review.
    PMID: 12782616
    doi: 10.1161/01.CIR.0000069566.78305.33

    This review will be limited specifically to the beneficial prevention by the n-3 polyunsaturated fatty acids (PUFAs) of arrhythmic deaths, including sudden cardiac death, which annually causes some 300 000 deaths in the United States and millions more worldwide. We will also show that the growing body of positive clinical studies is supported by what has been learned in animal and laboratory studies regarding the mechanism by which n-3 PUFAs prevent cardiac arrhythmias.
Matti Narkia

Fish Oil Consumption and Reduction of Arterial Disease -- Vanschoonbeek et al. 133 (3):... - 0 views

  •  
    Here we propose that the beneficial effect of (n-3) PUFA diet is related to down-regulation of the mutually positive interactions of platelet activation and coagulation. In addition, we consider the possibility that the dietary effect on hemostatic and lipid factors involves transcription regulation of multiple genes, perhaps in a subject-dependent manner.

    Fish oil consumption and reduction of arterial disease.
    Vanschoonbeek K, de Maat MP, Heemskerk JW.
    J Nutr. 2003 Mar;133(3):657-60. Review.
    PMID: 12612132
Matti Narkia

Multi-targeted therapy of cancer by omega-3 fatty acids - Cancer Lett. 2008 Oct 8 - 0 views

  •  
    Multi-targeted therapy of cancer by omega-3 fatty acids.
    Berquin IM, Edwards IJ, Chen YQ.
    Cancer Lett. 2008 Oct 8;269(2):363-77. Epub 2008 May 13. Review.
    PMID: 18479809
    doi:10.1016/j.canlet.2008.03.044
Matti Narkia

Fatty acid facts, part III: Cardiovascular disease, or, a fish diet is noy fishy. - [Dr... - 0 views

  •  
    Fatty acid facts, part III: Cardiovascular disease, or, a fish diet is noy fishy.
    Pauwels EK, Kostkiewicz M.
    Drug News Perspect. 2008 Dec;21(10):552-61.
    PMID: 19221636
Matti Narkia

Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 ... - 0 views

  •  
    Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies.
    Jakobsen MU, O'Reilly EJ, Heitmann BL, Pereira MA, Bälter K, Fraser GE, Goldbourt U, Hallmans G, Knekt P, Liu S, Pietinen P, Spiegelman D, Stevens J, Virtamo J, Willett WC, Ascherio A.
    Am J Clin Nutr. 2009 Feb 11. [Epub ahead of print]
    PMID: 19211817
    doi:10.3945/ajcn.2008.27124
Matti Narkia

Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary h... - 0 views

  •  
    Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: A meta-analysis of randomized controlled trials.\nZhao YT, Chen Q, Sun YX, Li XB, Zhang P, Xu Y, Guo JH.\nAnn Med. 2009 Jan 16:1-10. [Epub ahead of print]\nPMID: 19148838
Matti Narkia

Prevention of insulin resistance by n-3 polyunsaturated fatty acids. - [Curr Opin Clin ... - 0 views

  •  
    Prevention of insulin resistance by n-3 polyunsaturated fatty acids.\nFedor D, Kelley DS.\nCurr Opin Clin Nutr Metab Care. 2009 Mar;12(2):138-46.\nPMID: 19202385
Matti Narkia

n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefi... - 0 views

  •  
    Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupelnick B, Jordan HS, Lau J. \nn-3 Fatty acids from fish or fish-oil supplements, but not \nalpha-linolenic acid, benefit cardiovascular disease outcomes in \nprimary- and secondary-prevention studies: a systematic review. \nAm J Clin Nutr. 2006 Jul;84(1):5-17. Review. \nPMID: 16825676
Matti Narkia

n-3 fatty acid dietary recommendations and food sources to achieve essentiality and car... - 0 views

  •  
    n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits.
    Gebauer SK, Psota TL, Harris WS, Kris-Etherton PM.
    Am J Clin Nutr. 2006 Jun;83(6 Suppl):1526S-1535S. Review.
    PMID: 16841863

    Dietary recommendations have been made for n-3 fatty acids, including {alpha}-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) to achieve nutrient adequacy and to prevent and treat cardiovascular disease. These recommendations are based on a large body of evidence from epidemiologic and controlled clinical studies. The n-3 fatty acid recommendation to achieve nutritional adequacy, defined as the amount necessary to prevent deficiency symptoms, is 0.6-1.2% of energy for ALA; up to 10% of this can be provided by EPA or DHA. To achieve recommended ALA intakes, food sources including flaxseed and flaxseed oil, walnuts and walnut oil, and canola oil are recommended. The evidence base supports a dietary recommendation of {approx}500 mg/d of EPA and DHA for cardiovascular disease risk reduction. For treatment of existing cardiovascular disease, 1 g/d is recommended. These recommendations have been embraced by many health agencies worldwide. A dietary strategy for achieving the 500-mg/d recommendation is to consume 2 fish meals per week (preferably fatty fish). Foods enriched with EPA and DHA or fish oil supplements are a suitable alternate to achieve recommended intakes and may be necessary to achieve intakes of 1 g/d.
Matti Narkia

Nutrition and cancer: A review of the evidence for an anti-cancer diet - Nutrition Jour... - 0 views

  •  
    Donaldson MS.
    Nutrition and cancer: a review of the evidence for an anti-cancer diet.
    Nutr J. 2004 Oct 20;3:19.
    PMID: 15496224
Matti Narkia

Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential ... - 0 views

  •  
    Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms.
    Larsson SC, Kumlin M, Ingelman-Sundberg M, Wolk A.
    Am J Clin Nutr. 2004 Jun;79(6):935-45. Review.
    PMID: 15159222
1 - 14 of 14
Showing 20 items per page