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Matti Narkia

Reducing the Burden of Disease Through Adequate Intake of Vitamin D3 by William B. Gran... - 0 views

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    Reducing the Burden of Disease Through Adequate Intake of Vitamin D3.
    A presentation at University of California, San Diego,
    April 9, 2008
    by William B. Grant, Ph.D
Matti Narkia

NEJM -- Fish Consumption and the 30-Year Risk of Fatal Myocardial Infarction - 0 views

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    Fish consumption and the 30-year risk of fatal myocardial infarction.
    Daviglus ML, Stamler J, Orencia AJ, Dyer AR, Liu K, Greenland P, Walsh MK, Morris D, Shekelle RB.
    N Engl J Med. 1997 Apr 10;336(15):1046-53.
    PMID: 9091800

    Conclusions These data show an inverse association between fish consumption and death from coronary heart disease, especially nonsudden death from myocardial infarction.
Matti Narkia

A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors an... - 0 views

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    A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
    Mente A, de Koning L, Shannon HS, Anand SS.
    Arch Intern Med. 2009 Apr 13;169(7):659-69. Review.
    PMID: 19364995

    Conclusions The evidence supports a valid association of a limited number of dietary factors and dietary patterns with CHD. Future evaluation of dietary patterns, including their nutrient and food components, in cohort studies and randomized trials is recommended
Matti Narkia

Single food focus dietary guidance: lessons learned from an economic analysis of egg co... - 0 views

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    Single food focus dietary guidance: lessons learned from an economic analysis of egg consumption.
    Schmier JK, Barraj LM, Tran NL.
    Cost Eff Resour Alloc. 2009 Apr 14;7:7.
    PMID: 19366457

    Methods
    A risk apportionment model estimated the increased risk for coronary heart disease (CHD) attributable to egg cholesterol content, the decreased risk for other conditions (age-related macular degeneration (AMD), cataract, neural tube defects, and sarcopenia) associated with egg consumption, and a literature search identified the cost of illness of each condition. The base 795 case scenario calculated the costs or savings of each condition attributable to egg cholesterol or nutrient content.

    Results
    Given the costs associated with CHD and the benefits associated with the other conditions, the most likely scenario associated with eating an egg a day is savings of $2.82 billion annually with uncertainty ranging from a net cost of $756 million to net savings up to $8.50 billion.

    Conclusion
    This study evaluating the economic impact of egg consumption suggests that public health campaigns promoting limiting egg consumption as a means to reduce CHD risk would not be cost-effective from a societal perspective when other benefits are considered. Public health intervention that focuses on a single dietary constituent, and foods that are high in that constituent, may lead to unintended consequences of removing other beneficial constituents and the net effect may not be in its totality a desirable public health outcome. As newer data become available, the model should be updated.
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the Phys... - 0 views

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    Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study.
    Djoussé L, Gaziano JM.
    Am J Clin Nutr. 2008 Apr;87(4):964-9.
    PMID: 18400720

    Results: In an average follow-up of 20 y, 1550 new myocardial infarctions (MIs), 1342 incident strokes, and 5169 deaths occurred. Egg consumption was not associated with incident MI or stroke in a multivariate Cox regression. In contrast, adjusted hazard ratios (95% CI) for mortality were 1.0 (reference), 0.94 (0.87, 1.02), 1.03 (0.95, 1.11), 1.05 (0.93, 1.19), and 1.23 (1.11, 1.36) for the consumption of <1, 1>< 0.0001). This association was stronger among diabetic subjects, in whom the risk of death in a comparison of the highest with the lowest category of egg consumption was twofold (hazard ratio: 2.01; 95% CI: 1.26, 3.20; P for interaction = 0.09).

    Conclusions: Infrequent egg consumption does not seem to influence the risk of CVD in male physicians. In addition, egg consumption was positively related to mortality, more strongly so in diabetic subjects, in the study population.
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the story gets mor... - 0 views

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    Egg consumption in relation to cardiovascular disease and mortality: the story gets more complex.
    Eckel RH.
    Am J Clin Nutr. 2008 Apr;87(4):799-800.
    PMID: 1840069
Matti Narkia

JAMA -- A Prospective Study of Egg Consumption and Risk of Cardiovascular Disease in Me... - 0 views

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    A prospective study of egg consumption and risk of cardiovascular disease in men and women.
    Hu FB, Stampfer MJ, Rimm EB, Manson JE, Ascherio A, Colditz GA, Rosner BA, Spiegelman D, Speizer FE, Sacks FM, Hennekens CH, Willett WC.
    JAMA. 1999 Apr 21;281(15):1387-94.
    PMID: 10217054

    Results We documented 866 incident cases of CHD and 258 incident cases of stroke in men during 8 years of follow-up and 939 incident cases of CHD and 563 incident cases of stroke in women during 14 years of follow-up. After adjustment for age, smoking, and other potential CHD risk factors, we found no evidence of an overall significant association between egg consumption and risk of CHD or stroke in either men or women. The relative risks (RRs) of CHD across categories of intake were less than 1 per week (1.0), 1 per week (1.06), 2 to 4 per week (1.12), 5 to 6 per week (0.90), and >=1 per day (1.08) (P for trend=.75) for men; and less than 1 per week (1.0), 1 per week (0.82), 2 to 4 per week (0.99), 5 to 6 per week (0.95), and >=1 per day (0.82) (P for trend=.95) for women. In subgroup analyses, higher egg consumption appeared to be associated with increased risk of CHD only among diabetic subjects (RR of CHD comparing more than 1 egg per day with less than 1 egg per week among diabetic men, 2.02 [95% confidence interval, 1.05-3.87; P for trend=.04], and among diabetic women, 1.49 [0.88-2.52; P for trend=.008]).

    Conclusions These findings suggest that consumption of up to 1 egg per day is unlikely to have substantial overall impact on the risk of CHD or stroke among healthy men and women. The apparent increased risk of CHD associated with higher egg consumption among diabetic participants warrants further research.
Matti Narkia

Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic ac... - 0 views

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    Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men.
    Tricon S, Burdge GC, Jones EL, Russell JJ, El-Khazen S, Moretti E, Hall WL, Gerry AB, Leake DS, Grimble RF, Williams CM, Calder PC, Yaqoob P.
    Am J Clin Nutr. 2006 Apr;83(4):744-53.
    PMID: 16600923

    CONCLUSION: Dairy products naturally enriched with cis-9,trans-11 CLA and trans-11 18:1 do not appear to have a significant effect on the blood lipid profile
Matti Narkia

Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial in... - 0 views

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    Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction.
    Singh RB, Neki NS, Kartikey K, Pella D, Kumar A, Niaz MA, Thakur AS.
    Mol Cell Biochem. 2003 Apr;246(1-2):75-82.
    PMID: 12841346
Matti Narkia

Blood -- Regression of warfarin-induced medial elastocalcinosis by high intake of vitam... - 0 views

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    Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats.
    Schurgers LJ, Spronk HM, Soute BA, Schiffers PM, DeMey JG, Vermeer C.
    Blood. 2007 Apr 1;109(7):2823-31.
    PMID: 17138823
    DOI 10.1182/blood-2006-07-035345.

    This is the first study in rats demonstrating that AC and the resulting decreased arterial distensibility are reversible by high-VK intake
Matti Narkia

Japan EPA Lipid Intervention Study (JELIS) - Дискуссионный Клуб Русского Меди... - 0 views

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    "18 645 patients with a total cholesterol of 6·5 mmol/L or greater were recruited from local physicians throughout Japan between 1996 and 1999. Patients were randomly assigned to receive either 1800 mg of EPA daily with statin (EPA group; n=9326) or statin only (controls; n=9319) with a 5-year follow-up. The primary endpoint was any major coronary event, including sudden cardiac death, fatal and non-fatal myocardial infarction, and other non-fatal events including unstable angina pectoris, angioplasty, stenting, or coronary artery bypass grafting. Analysis was by intention-to-treat.
    Findings
    At mean follow-up of 4·6 years, we detected the primary endpoint in 262 (2·8%) patients in the EPA group and 324 (3·5%) in controls-a 19% relative reduction in major coronary events (p=0·011). Post-treatment LDL cholesterol concentrations decreased 25%, from 4·7 mmol/L in both groups. Serum LDL cholesterol was not a significant factor in a reduction of risk for major coronary events. Unstable angina and non-fatal coronary events were also significantly reduced in the EPA group. Sudden cardiac death and coronary death did not differ between groups. In patients with a history of coronary artery disease who were given EPA treatment, major coronary events were reduced by 19% (secondary prevention subgroup: 158 [8·7%] in the EPA group vs 197 [10·7%] in the control group; p=0·048). In patients with no history of coronary artery disease, EPA treatment reduced major coronary events by 18%, but this finding was not significant (104 [1·4%] in the EPA group vs 127 [1·7%] in the control group; p=0·132)."
Matti Narkia

Dietary Mono- and Polyunsaturated Fatty Acids Similarly Affect LDL Size in Healthy Men ... - 0 views

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    Dietary mono- and polyunsaturated fatty acids similarly affect LDL size in healthy men and women.
    Kratz M, Gülbahçe E, von Eckardstein A, Cullen P, Cignarella A, Assmann G, Wahrburg U.
    J Nutr. 2002 Apr;132(4):715-8.
    PMID: 11925466

    In conclusion, our data indicate that dietary unsaturated fat similarly reduces LDL size relative to saturated fat. However, the small magnitude of this reduction also suggests that the composition of dietary fat is not a major factor affecting LDL size.
Matti Narkia

Vitamin K may reverse arterial calcification - study - 0 views

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    Arterial calcification, a process of hardening of the arteries, may be inhibited and even reversed with supplementation with high-dose vitamin K, suggests an animal study.
Matti Narkia

What can we expect from omega-3 fatty acids? - Cleveland Clinic Journal of Medicine - 0 views

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    What can we expect from omega-3 fatty acids?
    Chan EJ, Cho L.
    Cleve Clin J Med. 2009 Apr;76(4):245-51.
    PMID: 19339640
    doi: 10.3949/ccjm.76a.08042
Matti Narkia

A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors an... - 0 views

  •  
    A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
    Mente A, de Koning L, Shannon HS, Anand SS.
    Arch Intern Med. 2009 Apr 13;169(7):659-69.
    PMID: 19364995
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the Physicians' He... - 0 views

  •  
    Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study.
    Djoussé L, Gaziano JM.
    Am J Clin Nutr. 2008 Apr;87(4):964-9.
    PMID: 18400720

    Conclusions: Infrequent egg consumption does not seem to influence the risk of CVD in male physicians. In addition, egg consumption was positively related to mortality, more strongly so in diabetic subjects, in the study population.
Matti Narkia

Effects of olive oil polyphenols on erythrocyte oxidative damage. - Wiley InterScience ... - 0 views

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    Effects of olive oil polyphenols on erythrocyte oxidative damage.
    Paiva-Martins F, Fernandes J, Rocha S, Nascimento H, Vitorino R, Amado F, Borges F, Belo L, Santos-Silva A.
    Mol Nutr Food Res. 2009 Apr 2. [Epub ahead of print]
    PMID: 19340892
    DOI: 10.1002/mnfr.200800276
Matti Narkia

Source Of Major Health Benefits In Olive Oil Revealed - 0 views

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    ScienceDaily (Apr. 2, 2009) - Scientists have pinned down the constituent of olive oil that gives greatest protection from heart attack and stroke. In a study of the major antioxidants in olive oil, Portuguese researchers showed that one, DHPEA-EDA, protects red blood cells from damage more than any other part of olive oil.
Matti Narkia

Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammat... - 0 views

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    Z. Papoutsi, E. Kassi, I. Chinou, M. Halabalaki, L. A. Skaltsounis and P. Moutsatsou (2008).
    Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483.
    British Journal of Nutrition, 2008 Apr, 99 , pp 715-722
    PMID: 17916277
    doi:10.1017/S0007114507837421
Matti Narkia

JAMA -- A Prospective Study of Egg Consumption and Risk of Cardiovascular Disease in Me... - 0 views

  •  
    A prospective study of egg consumption and risk of cardiovascular disease in men and women.
    Hu FB, Stampfer MJ, Rimm EB, Manson JE, Ascherio A, Colditz GA, Rosner BA, Spiegelman D, Speizer FE, Sacks FM, Hennekens CH, Willett WC.
    JAMA. 1999 Apr 21;281(15):1387-94.
    PMID: 10217054

    CONCLUSIONS: These findings suggest that consumption of up to 1 egg per day is unlikely to have substantial overall impact on the risk of CHD or stroke among healthy men and women. The apparent increased risk of CHD associated with higher egg consumption among diabetic participants warrants further research.
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