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Matti Narkia

Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a lo... - 0 views

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    Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study.
    Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher BJ, Arden NK, Godfrey KM, Cooper C; Princess Anne Hospital Study Group.
    Lancet. 2006 Jan 7;367(9504):36-43. Erratum in: Lancet. 2006 May 6;367(9521):1486.
    PMID: 16399151
    doi:10.1016/S0140-6736(06)67922-1

    Interpretation
    Maternal vitamin D insufficiency is common during pregnancy and is associated with reduced bone-mineral accrual in the offspring during childhood; this association is mediated partly through the concentration of umbilical venous calcium. Vitamin D supplementation of pregnant women, especially during winter months, could lead to longlasting reductions in the risk of osteoporotic fracture in their offspring.
Matti Narkia

Role of vitamin K2 in the treatment of postmenopausal osteoporosis. - Curr Drug Saf. 20... - 0 views

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    Role of vitamin K2 in the treatment of postmenopausal osteoporosis.
    Iwamoto J, Takeda T, Sato Y.
    Curr Drug Saf. 2006 Jan;1(1):87-97. Review.
    PMID: 18690918
Matti Narkia

[Vitamin K2] [Clin Calcium. 2008] - PubMed result - 0 views

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    [Vitamin K2]
    Ishida Y.
    Clin Calcium. 2008 Oct;18(10):1476-82. Review. Japanese.
    PMID: 18830045

    "Vitamin K2 has been approved for the treatment of osteoporosis in Japan since 1995. Vitamin K2 treatment in osteoporosis has been shown to inhibit the occurrence of new bone fractures and to maintain BMD. The uniqueness of the prevention of bone fractures by vitamin K2 is that there has been no direct evidence of the relationship between increase of BMD and a decrease in the occurrence of bone fractures. A recent systematic review of seven Japanese randomized controlled trials by Cockayne has also shown that supplementation with phytonadione (Vitamin K1) and menaquinone (Vitamin K2) , particularly menaquinone-4, is associated with increased BMD and reduced fracture incidence. To confirm these results, a larger well design RCT using fractures as the primary endpoint is clearly needed."
Matti Narkia

Effect of vitamin K2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovari... - 0 views

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    Effect of vitamin K2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovariectomized rats.
    Yamaguchi M, Taguchi H, Gao YH, Igarashi A, Tsukamoto Y.
    J Bone Miner Metab. 1999;17(1):23-9.
    PMID: 10084398

    This study demonstrates that the intake of dietary MK-7 has a preventive effect on bone loss caused by OVX. This effect may be partly caused by MK-4, which is formed by degradation of MK-7.
Matti Narkia

Is a lower dose of vitamin D supplementation enough to increase 25(OH)D status in a sun... - 0 views

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    Is a lower dose of vitamin D supplementation enough to increase 25(OH)D status in a sunny country?
    Pignotti GA, Genaro PS, Pinheiro MM, Szejnfeld VL, Martini LA.
    Eur J Nutr. 2009 Nov 28. [Epub ahead of print]
    PMID: 19946776

    CONCLUSION: The dose given (400 IU/day) was not enough to achieve 25(OH)D concentration, considered optimal for bone health.
Matti Narkia

Vitamin D deficiency is associated with worse cognitive performance and lower bone dens... - 0 views

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    Vitamin D deficiency is associated with worse cognitive performance and lower bone density in older African Americans.
    Wilkins CH, Birge SJ, Sheline YI, Morris JC.
    J Natl Med Assoc. 2009 Apr;101(4):349-54.
    PMID: 19397226

    CONCLUSIONS: Vitamin D deficiency in older African Americans was associated with worse cognitive performance and lower BMD of the hip
Matti Narkia

Dietary protein and bone health: a systematic review and meta-analysis -- Darling et al... - 0 views

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    Dietary protein and bone health: a systematic review and meta-analysis.
    Darling AL, Millward DJ, Torgerson DJ, Hewitt CE, Lanham-New SA.
    Am J Clin Nutr. 2009 Nov 4. [Epub ahead of print]
    PMID: 19889822
Matti Narkia

Effectiveness and safety of vitamin D in relation to bone health. - [Evid Rep Technol A... - 0 views

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    Effectiveness and safety of vitamin D in relation to bone health.
    Cranney A, Horsley T, O'Donnell S, Weiler H, Puil L, Ooi D, Atkinson S, Ward L, Moher D, Hanley D, Fang M, Yazdi F, Garritty C, Sampson M, Barrowman N, Tsertsvadze A, Mamaladze V.
    Evid Rep Technol Assess (Full Rep). 2007 Aug;(158):1-235. Review.
    PMID: 18088161
Matti Narkia

African Americans, 25-hydroxyvitamin D, and osteoporosis: a paradox -- Aloia 88 (2): 54... - 0 views

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    African Americans, 25-hydroxyvitamin D, and osteoporosis: a paradox.
    Aloia JF.
    Am J Clin Nutr. 2008 Aug;88(2):545S-550S. Review.
    PMID: 18689399
Matti Narkia

Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elder... - 0 views

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    Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elderly men and women.
    Dawson-Hughes B, Harris SS, Dallal GE.
    Am J Clin Nutr. 1997 Jan;65(1):67-71.
    PMID: 8988915

    Plasma calcidiol and serum PTH concentrations were inversely related, with PTH rising slowly as calcidiol concentrations declined below 110 nmol/L (95 CI: 60, 168 nmol/L). More than 90% of the men and women had calcidiol concentrations below this value in the wintertime. The high prevalence of lower wintertime calcidiol values may increase risk of bone loss in elderly men and women.
Matti Narkia

Vitamin D and vitamin D analogues for preventing fractures associated with involutional... - 0 views

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    Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis.
    Avenell A, Gillespie WJ, Gillespie LD, O'Connell D.
    Cochrane Database Syst Rev. 2009 Apr 15;(2):CD000227. Review.
    PMID: 19370554
    DOI: 10.1002/14651858.CD000227.pub3

    AUTHORS' CONCLUSIONS: Frail older people confined to institutions may sustain fewer hip fractures if given vitamin D with calcium. Vitamin D alone is unlikely to prevent fracture. Overall there is a small but significant increase in gastrointestinal symptoms and renal disease associated with vitamin D or its analogues. Calcitriol is associated with an increased incidence of hypercalcaemia.
Matti Narkia

Vitamin K and the Prevention of Fractures: Systematic Review and Meta-analysis of Rando... - 0 views

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    Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S, Adamson J, Lanham-New S, Shearer MJ, Gilbody S, Torgerson DJ.
    Arch Intern Med. 2006 Jun 26;166(12):1256-61. Review.
    PMID: 16801507

    Conclusions This systematic review suggests that supplementation with phytonadione and menaquinone-4 reduces bone loss. In the case of the latter, there is a strong effect on incident fractures among Japanese patients.
Matti Narkia

Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset... - 0 views

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    Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density.
    Abreu MT, Kantorovich V, Vasiliauskas EA, Gruntmanis U, Matuk R, Daigle K, Chen S, Zehnder D, Lin YC, Yang H, Hewison M, Adams JS.
    Gut. 2004 Aug;53(8):1129-36.
    PMID: 15247180
    doi: 10.1136/gut.2003.036657.

    Conclusions: These data demonstrate that elevated 1,25(OH)2D is more common in CD than previously appreciated and is independently associated with low bone mineral density. The source of the active vitamin D may be the inflamed intestine. Treatment of the underlying inflammation may improve metabolic bone disease in this subgroup of patients.
Matti Narkia

NEJM -- Vitamin D3 and calcium to prevent hip fractures in the elderly women - 0 views

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    Vitamin D3 and calcium to prevent hip fractures in the elderly women.
    Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ.
    N Engl J Med. 1992 Dec 3;327(23):1637-42.
    PMID: 1331788

    CONCLUSIONS. Supplementation with vitamin D3 and calcium reduces the risk of hip fractures and other nonvertebral fractures among elderly women.
Matti Narkia

Vitamin D deficiency and bone health in healthy adults in Finland: could this be a conc... - 0 views

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    Vitamin D deficiency and bone health in healthy adults in Finland: could this be a concern in other parts of Europe?
    Lamberg-Allardt CJ, Outila TA, Kärkkainen MU, Rita HJ, Valsta LM.
    J Bone Miner Res. 2001 Nov;16(11):2066-73.
    PMID: 11697803

    Low vitamin D status was prevalent in these young adults in northern Europe in winter, although the vitamin D intake met the recommendation. This probably is not a local problem for northern Europe, because the natural sources of vitamin D are scarce and fortification is not very common in Europe, and with the exception of the southern part of Europe, sunshine is not very abundant in this part of the world. Thus, the results of this study indicate that more attention should be focused on vitamin D status and the sources of vitamin D in these countries.
Matti Narkia

Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual a... - 0 views

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    Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial.
    Cheng S, Lyytikäinen A, Kröger H, Lamberg-Allardt C, Alén M, Koistinen A, Wang QJ, Suuriniemi M, Suominen H, Mahonen A, Nicholson PH, Ivaska KK, Korpela R, Ohlsson C, Väänänen KH, Tylavsky F.
    Am J Clin Nutr. 2005 Nov;82(5):1115-26; quiz 1147-8.
    PMID: 16280447
Matti Narkia

Reducing fracture risk with calcium and vitamin D. - Wiley InterScience :: JO... - 0 views

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    Reducing fracture risk with calcium and vitamin D.
    Lips P, Bouillon R, van Schoor NM, Vanderschueren D, Verschueren S, Kuchuk N, Milisen K, Boonen S.
    Clin Endocrinol (Oxf). 2009 Sep 10. [Epub ahead of print]
    PMID: 19744099
    DOI: 10.1111/j.0300-0664.2009.03701.x
Matti Narkia

Estimates of optimal vitamin D status. - Osteoporos Int. 2005 Jul;16(7):713-6. - Spring... - 0 views

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    Estimates of optimal vitamin D status.
    Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R.
    Osteoporos Int. 2005 Jul;16(7):713-6. Epub 2005 Mar 18.
    PMID: 15776217
Matti Narkia

RANK ligand and TNF-{alpha} mediate acid-induced bone calcium efflux in vitro -- Frick ... - 0 views

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    Frick KK, LaPlante K, Bushinsky DA.
    RANK ligand and TNF-alpha mediate acid-induced bone calcium efflux in vitro.
    Am J Physiol Renal Physiol. 2005 Nov;289(5):F1005-11. Epub 2005 Jun 21.
    PMID: 15972386 [PubMed - indexed for MEDLINE
Matti Narkia

Cortisol Inhibits Acid-Induced Bone Resorption In Vitro -- Krieger et al. 13 (10): 2534... - 0 views

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    Krieger NS, Frick KK, Bushinsky DA.
    Cortisol inhibits acid-induced bone resorption in vitro.
    J Am Soc Nephrol. 2002 Oct;13(10):2534-9.
    PMID: 12239242 [PubMed - indexed for MEDLINE]
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