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Matti Narkia

Statins and Vitamin D - 0 views

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    Statins and vitamin D.
    Aloia JF, Li-Ng M, Pollack S.
    Am J Cardiol. 2007 Oct 15;100(8):1329. Epub 2007 Jul 5. No abstract available.
    PMID: 17920383

    A total of 208 women were randomized to receive vitamin D3 (n=104) or placebo (n=104). 51 women were on statins. At baseline, the subjects on statins had a significantly higher 25-OHD level than the subjects who were not on statins (51.2 ± 20.1 nmol/L versus 43.2 ± 18.0 nmol/L respectively, p=0.008). This was also true when averaging 25-OHD levels across the 3-year study period and looking at active and placebo patients separately. 185 subjects had follow-up 25-OHD levels drawn every 6 months during the study. Higher levels were seen in the statin use subgroup whether they were on placebo or active vitamin D (Figure 1Figure 1). There was no interaction seen between vitamin D use and statin use, i.e. the impacts are additive (p=0.5502). This significant difference is comparable to the increase in 25-OHD levels seen in Pérez-Castrillón's study (41 ± 19 versus 47 ± 19 nmol/L, p=0.003) [1]. Although Pérez-Castrillón et al found a statistically significant relation between total cholesterol and 25-OHD (r=0.277, p=0.002), we did not find a significant relation between total cholesterol and 25-OHD in our study population.
Matti Narkia

Are Omega-3 Fatty Acids Effective in Enhancing Tumoricidal Cell Activity? - Are Omega-3... - 0 views

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    K. L. Fritsche
    Are Omega-3 Fatty Acids Effective in Enhancing Tumoricidal Cell Activity?
    J. Nutr., December 1, 2005; 135(12): 2916S - 2917S.
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