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Matti Narkia

Pharmacokinetics of a single, large dose of cholecalciferol -- Ilahi et al. 87 (3): 688... - 0 views

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    Pharmacokinetics of a single, large dose of cholecalciferol.
    Ilahi M, Armas LA, Heaney RP.
    Am J Clin Nutr. 2008 Mar;87(3):688-91.
    PMID: 1832660

    Conclusions: Cholecalciferol (100 000 IU) is a safe, effective, and simple way to increase calcidiol concentrations. The dosing interval should be ≤2 mo to ensure continuous serum calcidiol concentrations above baseline.

    Our study highlights that 100 000 IU cholecalciferol is a safe, efficient, and cost-effective means to increase calcidiol concentrations in the elderly. From this study we can safely recommend 100 000 IU cholecalciferol dosed every 2 mo in persons with moderate baseline calcidiol concentrations. However, in those persons with baseline calcidiol concentrations < 20 ng/mL, even this large dose will not adequately raise their calcidiol concentrations.
Matti Narkia

Clinical aspects of vitamin D in the management of rheumatoid arthritis. - Rheumatology... - 0 views

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    Clinical aspects of vitamin D in the management of rheumatoid arthritis.\nLeventis P, Patel S.\nRheumatology (Oxford). 2008 Nov;47(11):1617-21. Epub 2008 Aug 5. Review.\nPMID: 18682414 \ndoi:10.1093/rheumatology/ken296 \n
Matti Narkia

The controversial place of vitamin C in cancer treatment - ScienceDirect - Biochemical ... - 0 views

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    The controversial place of vitamin C in cancer treatment.
    Verrax J, Calderon PB.
    Biochem Pharmacol. 2008 Dec 15;76(12):1644-52. Epub 2008 Sep 30. Review.
    PMID: 18938145
    doi:10.1016/j.bcp.2008.09.024    
Matti Narkia

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. - Ann Oncol. 2008 ... - 0 views

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    Phase I clinical trial of i.v. ascorbic acid in advanced malignancy.
    Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr.
    Ann Oncol. 2008 Nov;19(11):1969-74. Epub 2008 Jun 9. Erratum in: Ann Oncol. 2008 Dec;19(12):2095.
    PMID: 18544557
    doi:10.1093/annonc/mdn377
Matti Narkia

Vitamin C and cancer revisited - PNAS - 0 views

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    Vitamin C and cancer revisited.
    Frei B, Lawson S.
    Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11037-8. Epub 2008 Aug 5.
    PMID: 18682554
Matti Narkia

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

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    Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice.
    Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M.
    Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4.
    PMID: 18678913
    doi: 10.1073/pnas.0804226105
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