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Matti Narkia

Egg consumption and endothelial function: a randomized controlled crossover trial - 0 views

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    Egg consumption and endothelial function: a randomized controlled crossover trial.
    Katz DL, Evans MA, Nawaz H, Njike VY, Chan W, Comerford BP, Hoxley ML.
    Int J Cardiol. 2005 Mar 10;99(1):65-70.
    PMID: 15721501

    Conclusion: Short-term egg consumption does not adversely affect endothelial function in healthy adults, supporting the view that dietary cholesterol may be less detrimental to cardiovascular health than previously thought
Matti Narkia

Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty aci... - 0 views

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    Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty acids.
    Ohman M, Akerfeldt T, Nilsson I, Rosen C, Hansson LO, Carlsson M, Larsson A.
    Ups J Med Sci. 2008;113(3):315-23.P
    MID: 18991244

    Today, eggs with an increased content of -3 fatty acids are available but there are few publications on the effects of consumption of such eggs on the lipoproteins and acute phase markers in humans. The aim of the present study was to evaluate the effects of consumption of standard eggs and -3 enriched eggs on lipoproteins, glucose and inflammation markers. Nineteen healthy volunteers consumed one extra egg per day of either standard eggs or omega-3 enriched eggs in a double-blind, cross-over study. The duration of each period was 1 month. The effects of the different egg diets on apolipoprotein A1 and B (Apo A1 and B), lipoprotein (a), creatinine, cystatin C, C-reactive protein, serum amyloid protein A, interleukin 6, triglycerides, glucose, total-, high-density lipoprotein and low-density lipo-protein cholesterol concentrations were analyzed. Addition of one regular egg per day to the normal diet had no negative impact on blood lipids or inflammation markers. Consumption of omega-3 enriched eggs resulted in higher levels of ApoA1, lower ApoB/ApoA1 ratio and lower plasma glucose. These effects have been associated in previous studies with a reduced risk for cardiovascular mortality and diabetes.
Matti Narkia

A comparison of egg consumption with other modifiable coronary heart disease lifestyle ... - 0 views

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    A comparison of egg consumption with other modifiable coronary heart disease lifestyle risk factors: a relative risk apportionment study.
    Barraj L, Tran N, Mink P.
    Risk Anal. 2009 Mar;29(3):401-15. Epub 2008 Nov 4.
    PMID: 19000074
    DOI: 10.1111/j.1539-6924.2008.01149.x

    Guidelines from the American Heart Association (AHA) recommend that healthy adults limit their intake of dietary cholesterol to less than 300 mg per day. Since a large egg contains about 71% of that amount, the AHA recommends restricting egg consumption unless dietary cholesterol intakes from other sources are limited. We applied a risk apportionment approach to estimate the contribution of egg consumption and other modifiable lifestyle risk factors (e.g., smoking, poor diet, minimal exercise, and alcohol intake) to coronary heart disease (CHD) risk at the population level. Specifically, we categorized the U.S. adult population ages 25+ into distinct risk groups based on the prevalence of modifiable lifestyle risk factors and applied an apportionment model, typically used to assess risk contribution at the individual level, to estimate the contribution of egg intake to CHD risk. Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for <1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.
Matti Narkia

Single food focus dietary guidance: lessons learned from an economic analysis of egg co... - 0 views

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    Single food focus dietary guidance: lessons learned from an economic analysis of egg consumption.
    Schmier JK, Barraj LM, Tran NL.
    Cost Eff Resour Alloc. 2009 Apr 14;7:7.
    PMID: 19366457

    Methods
    A risk apportionment model estimated the increased risk for coronary heart disease (CHD) attributable to egg cholesterol content, the decreased risk for other conditions (age-related macular degeneration (AMD), cataract, neural tube defects, and sarcopenia) associated with egg consumption, and a literature search identified the cost of illness of each condition. The base 795 case scenario calculated the costs or savings of each condition attributable to egg cholesterol or nutrient content.

    Results
    Given the costs associated with CHD and the benefits associated with the other conditions, the most likely scenario associated with eating an egg a day is savings of $2.82 billion annually with uncertainty ranging from a net cost of $756 million to net savings up to $8.50 billion.

    Conclusion
    This study evaluating the economic impact of egg consumption suggests that public health campaigns promoting limiting egg consumption as a means to reduce CHD risk would not be cost-effective from a societal perspective when other benefits are considered. Public health intervention that focuses on a single dietary constituent, and foods that are high in that constituent, may lead to unintended consequences of removing other beneficial constituents and the net effect may not be in its totality a desirable public health outcome. As newer data become available, the model should be updated.
Matti Narkia

Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men foll... - 0 views

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    Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men following a carbohydrate-restricted diet.
    Mutungi G, Waters D, Ratliff J, Puglisi M, Clark RM, Volek JS, Fernandez ML.
    J Nutr Biochem. 2009 Apr 13. [Epub ahead of print]
    PMID: 19369056

    We previously reported that carbohydrate restriction (CR) (10-15% en) during a weight loss intervention lowered plasma triglycerides (TG) by 45% in male subjects (P<.001). however><.0001) the consuming than lower amounts individuals><.001), low-density while small lipoprotein><.001). observations agreement in with these><.01) observed was><.0001). observed of larger although subclass the ldl increase was subjects all for an><.05). of group egg the number presented hdl higher large a also particles><.01) sub group the compared to><.001). contrast in><.05). However, only those subjects from the EGG group presented higher concentrations of these two carotenoids in plasma, which were correlated with the higher concentra
Matti Narkia

Meat, eggs, dairy products, and risk of breast cancer in the European Prospective Inves... - 0 views

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    Meat, eggs, dairy products, and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
    Pala V, Krogh V, Berrino F, Sieri S, Grioni S, Tjønneland A, Olsen A, Jakobsen MU, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Romieu I, Linseisen J, Rohrmann S, Boeing H, Steffen A, Trichopoulou A, Benetou V, Naska A, Vineis P, Tumino R, Panico S, Masala G, Agnoli C, Engeset D, Skeie G, Lund E, Ardanaz E, Navarro C, Sánchez MJ, Amiano P, Svatetz CA, Rodriguez L, Wirfält E, Manjer J, Lenner P, Hallmans G, Peeters PH, van Gils CH, Bueno-de-Mesquita HB, van Duijnhoven FJ, Key TJ, Spencer E, Bingham S, Khaw KT, Ferrari P, Byrnes G, Rinaldi S, Norat T, Michaud DS, Riboli E.
    Am J Clin Nutr. 2009 Sep;90(3):602-12. Epub 2009 Jun 2.
    PMID: 19491385
    doi:10.3945/ajcn.2008.27173

    Conclusions: We have not consistently identified intakes of meat, eggs, or dairy products as risk factors for breast cancer. Future studies should investigate the possible role of high-temperature cooking in the relation of red meat intake with breast cancer risk.
Matti Narkia

Meat and egg consumption and risk of breast cancer among Chinese women. - Cancer Causes... - 0 views

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    Meat and egg consumption and risk of breast cancer among Chinese women.
    Zhang CX, Ho SC, Chen YM, Lin FY, Fu JH, Cheng SZ.
    Cancer Causes Control. 2009 Jun 17. [Epub ahead of print]
    PMID: 19533390

    Conclusions This study suggested that processed meat intake was associated with a possible increased risk of breast cancer. There was no significant association between consumption of total and red meat, poultry, fish, or egg with breast cancer risk
Matti Narkia

Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in... - 0 views

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    Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in older adults with low macular pigment taking cholesterol-lowering statins.
    Vishwanathan R, Goodrow-Kotyla EF, Wooten BR, Wilson TA, Nicolosi RJ.
    Am J Clin Nutr. 2009 Nov;90(5):1272-9. Epub 2009 Sep 16.
    PMID: 19759170

    Conclusions: Consumption of 4 egg yolks/d, and possibly of 2 egg yolks/d, for 5 wk benefited macular health in older adults with low MPOD. Serum HDL cholesterol increased without an increase in LDL cholesterol in this study population, most of whom were taking cholesterol-lowering statins.
Matti Narkia

Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the Nat... - 0 views

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    Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the National Integrated Project for Prospective Observation of Non-communicable Disease and Its Trends in the Aged, 1980 (NIPPON DATA80).
    Nakamura Y, Okamura T, Tamaki S, Kadowaki T, Hayakawa T, Kita Y, Okayama A, Ueshima H; NIPPON DATA80 Research Group.
    Am J Clin Nutr. 2004 Jul;80(1):58-63.
    PMID: 15213028

    Results: The subjects were categorized into 5 egg consumption groups on the basis of their responses to a questionnaire (≥2/d, 1/d, 1/2 d, 1-2/wk, and seldom). There were 69, 1396, 1667, 1742, and 315 women in each of the 5 groups, respectively. Age-adjusted total cholesterol (5.21, 5.04, 4.95, 4.91, and 4.92 mmol/L in the 5 egg consumption categories, respectively) was related to egg consumption (P < 0.0001, analysis of covariance). In women, unadjusted IHD mortality and all-cause mortality differed significantly between the groups [IHD mortality: 1.1, 0.5, 0.4, 0.5, and 2.0 per 1000 person-years, respectively (P = 0.008, chi-square test); all-cause mortality: 14.8, 8.0, 7.5, 7.5, and 14.5 per 1000 person-years, respectively (P < 0.0001, chi-square test)]. In men, egg consumption was not related to age-adjusted total cholesterol. Cox analysis found that, in women, all-cause mortality in the 1-2-eggs/wk group was significantly lower than that in the 1-egg/d group, whereas no such relations were noted in men.

    Conclusion: Limiting egg consumption may have some health benefits, at least in women in geographic areas where egg consumption makes a relatively large contribution to total dietary cholesterol intake.
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the Phys... - 0 views

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    Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study.
    Djoussé L, Gaziano JM.
    Am J Clin Nutr. 2008 Apr;87(4):964-9.
    PMID: 18400720

    Results: In an average follow-up of 20 y, 1550 new myocardial infarctions (MIs), 1342 incident strokes, and 5169 deaths occurred. Egg consumption was not associated with incident MI or stroke in a multivariate Cox regression. In contrast, adjusted hazard ratios (95% CI) for mortality were 1.0 (reference), 0.94 (0.87, 1.02), 1.03 (0.95, 1.11), 1.05 (0.93, 1.19), and 1.23 (1.11, 1.36) for the consumption of <1, 1>< 0.0001). This association was stronger among diabetic subjects, in whom the risk of death in a comparison of the highest with the lowest category of egg consumption was twofold (hazard ratio: 2.01; 95% CI: 1.26, 3.20; P for interaction = 0.09).

    Conclusions: Infrequent egg consumption does not seem to influence the risk of CVD in male physicians. In addition, egg consumption was positively related to mortality, more strongly so in diabetic subjects, in the study population.
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the story gets mor... - 0 views

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    Egg consumption in relation to cardiovascular disease and mortality: the story gets more complex.
    Eckel RH.
    Am J Clin Nutr. 2008 Apr;87(4):799-800.
    PMID: 1840069
Matti Narkia

Egg Consumption and Risk of Type 2 Diabetes in Men and Women - Diabetes Care - 0 views

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    Egg consumption and risk of type 2 diabetes in men and women.
    Djoussé L, Gaziano JM, Buring JE, Lee IM.
    Diabetes Care. 2009 Feb;32(2):295-300. Epub 2008 Nov 18.
    PMID: 1901777
    doi: 10.2337/dc08-1271

    RESULTS-During mean follow-up of 20.0 years in men and 11.7 years in women, 1,921 men and 2,112 women developed type 2 diabetes. Compared with no egg consumption, multivariable adjusted hazard ratios for type 2 diabetes were 1.09 (95% CI 0.87-1.37), 1.09 (0.88-1.34), 1.18 (0.95-1.45), 1.46 (1.14-1.86), and 1.58 (1.25-2.01) for consumption of <1, 1><0.0001). hazard multivariable women ratios 1 were for corresponding><0.0001).

    CONCLUSIONS-These data suggest that high levels of egg consumption (daily) are associated with an increased risk of type 2 diabetes in men and women. Confirmation of these findings in other populations is warranted.
Matti Narkia

JAMA -- A Prospective Study of Egg Consumption and Risk of Cardiovascular Disease in Me... - 0 views

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    A prospective study of egg consumption and risk of cardiovascular disease in men and women.
    Hu FB, Stampfer MJ, Rimm EB, Manson JE, Ascherio A, Colditz GA, Rosner BA, Spiegelman D, Speizer FE, Sacks FM, Hennekens CH, Willett WC.
    JAMA. 1999 Apr 21;281(15):1387-94.
    PMID: 10217054

    Results We documented 866 incident cases of CHD and 258 incident cases of stroke in men during 8 years of follow-up and 939 incident cases of CHD and 563 incident cases of stroke in women during 14 years of follow-up. After adjustment for age, smoking, and other potential CHD risk factors, we found no evidence of an overall significant association between egg consumption and risk of CHD or stroke in either men or women. The relative risks (RRs) of CHD across categories of intake were less than 1 per week (1.0), 1 per week (1.06), 2 to 4 per week (1.12), 5 to 6 per week (0.90), and >=1 per day (1.08) (P for trend=.75) for men; and less than 1 per week (1.0), 1 per week (0.82), 2 to 4 per week (0.99), 5 to 6 per week (0.95), and >=1 per day (0.82) (P for trend=.95) for women. In subgroup analyses, higher egg consumption appeared to be associated with increased risk of CHD only among diabetic subjects (RR of CHD comparing more than 1 egg per day with less than 1 egg per week among diabetic men, 2.02 [95% confidence interval, 1.05-3.87; P for trend=.04], and among diabetic women, 1.49 [0.88-2.52; P for trend=.008]).

    Conclusions These findings suggest that consumption of up to 1 egg per day is unlikely to have substantial overall impact on the risk of CHD or stroke among healthy men and women. The apparent increased risk of CHD associated with higher egg consumption among diabetic participants warrants further research.
Matti Narkia

Egg consumption and coronary heart disease: an epidemiologic overview. - J Am Coll Nutr... - 0 views

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    Egg consumption and coronary heart disease: an epidemiologic overview.
    Kritchevsky SB, Kritchevsky D.
    J Am Coll Nutr. 2000 Oct;19(5 Suppl):549S-555S. Review.
    PMID: 11023006

    When dietary confounders were considered, no association was seen between egg consumption at levels up to 1 + egg per day and the risk of coronary heart disease in non-diabetic men and women.
Matti Narkia

Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the Nat... - 0 views

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    Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the National Integrated Project for Prospective Observation of Non-communicable Disease and Its Trends in the Aged, 1980 (NIPPON DATA80).
    Nakamura Y, Okamura T, Tamaki S, Kadowaki T, Hayakawa T, Kita Y, Okayama A, Ueshima H; NIPPON DATA80 Research Group.
    Am J Clin Nutr. 2004 Jul;80(1):58-63.
    PMID: 15213028

    In men, egg consumption was not related to age-adjusted total cholesterol. Cox analysis found that, in women, all-cause mortality in the 1-2-eggs/wk group was significantly lower than that in the 1-egg/d group, whereas no such relations were noted in men. CONCLUSION: Limiting egg consumption may have some health benefits, at least in women in geographic areas where egg consumption makes a relatively large contribution to total dietary cholesterol intake.
Matti Narkia

[Egg intake and cardiovascular risk] [Ther Umsch. 2005] - PubMed Result - 0 views

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    [Egg intake and cardiovascular risk]
    Schärer M, Schulthess G.
    Ther Umsch. 2005 Sep;62(9):611-3. Review. German.
    PMID: 16218496

    The egg - rich in proteins, unsaturated fatty acids, vitamins and minerals - should be part of our nutrition, and it is not justified to recommend a general limitation of egg intake. However, we do not advice unbalanced high egg consumption. A cardioprotective diet is characterized by high variability and contains plenty of fruits, vegetables, and complex carbohydrates.
Matti Narkia

Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in ... - 0 views

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    Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations.
    Goodrow EF, Wilson TA, Houde SC, Vishwanathan R, Scollin PA, Handelman G, Nicolosi RJ.
    J Nutr. 2006 Oct;136(10):2519-24.
    PMID: 16988120

    These findings indicate that in older adults, 5 wk of consuming 1 egg/d significantly increases serum lutein and zeaxanthin concentrations without elevating serum lipids and lipoprotein cholesterol concentrations.
Matti Narkia

Dietary cholesterol from eggs increases plasma HDL cholesterol in overweight men consum... - 0 views

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    Dietary cholesterol from eggs increases plasma HDL cholesterol in overweight men consuming a carbohydrate-restricted diet.
    Mutungi G, Ratliff J, Puglisi M, Torres-Gonzalez M, Vaishnav U, Leite JO, Quann E, Volek JS, Fernandez ML.
    J Nutr. 2008 Feb;138(2):272-6.
    PMID: 18203890

    Carbohydrate-restricted diets (CRD) significantly decrease body weight and independently improve plasma triglycerides (TG) and HDL cholesterol (HDL-C) .

    [..]

    Eighteen subjects were classified as having the metabolic syndrome (MetS) at the beginning of the study, whereas 3 subjects had that classification at the end. These results suggest that including eggs in a CRD results in increased HDL-C while decreasing the risk factors associated with MetS.
Matti Narkia

Egg consumption and risk of heart failure in the Physicians' Health Study. - Circulatio... - 0 views

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    Egg consumption and risk of heart failure in the Physicians' Health Study.
    Djoussé L, Gaziano JM.
    Circulation. 2008 Jan 29;117(4):512-6. Epub 2008 Jan 14.
    PMID: 18195171
    doi: 10.1161/CIRCULATIONAHA.107.734210

    CONCLUSIONS: Our data suggest that infrequent egg consumption is not associated with the risk of HF. However, egg consumption of > or = 1 per day is related to an increased risk of HF among US male physicians.
Matti Narkia

Egg consumption in relation to cardiovascular disease and mortality: the Physicians' He... - 0 views

  •  
    Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study.
    Djoussé L, Gaziano JM.
    Am J Clin Nutr. 2008 Apr;87(4):964-9.
    PMID: 18400720

    Conclusions: Infrequent egg consumption does not seem to influence the risk of CVD in male physicians. In addition, egg consumption was positively related to mortality, more strongly so in diabetic subjects, in the study population.
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