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Matti Narkia

Pharmacokinetics of a single, large dose of cholecalciferol -- Ilahi et al. 87 (3): 688... - 0 views

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    Pharmacokinetics of a single, large dose of cholecalciferol.
    Ilahi M, Armas LA, Heaney RP.
    Am J Clin Nutr. 2008 Mar;87(3):688-91.
    PMID: 1832660

    Conclusions: Cholecalciferol (100 000 IU) is a safe, effective, and simple way to increase calcidiol concentrations. The dosing interval should be ≤2 mo to ensure continuous serum calcidiol concentrations above baseline.

    Our study highlights that 100 000 IU cholecalciferol is a safe, efficient, and cost-effective means to increase calcidiol concentrations in the elderly. From this study we can safely recommend 100 000 IU cholecalciferol dosed every 2 mo in persons with moderate baseline calcidiol concentrations. However, in those persons with baseline calcidiol concentrations < 20 ng/mL, even this large dose will not adequately raise their calcidiol concentrations.
Matti Narkia

Vitamin D and Cancer Mini-Symposium: The Risk of Additional Vitamin D - 0 views

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    Evidence from clinical trials shows, with a wide margin of confidence, that a prolonged intake of 10,000IU/d of vitamin D3 poses no risk of adverse effects for adults, even if this is added to a rather high physiologic background level of vitamin D.

    Vitamin D and cancer mini-symposium: the risk of additional vitamin D.
    Vieth R.\nAnn Epidemiol. 2009 Jul;19(7):441-5. Epub 2009 Apr 11.
    PMID: 19364661
    doi:10.1016/j.annepidem.2009.01.009
Matti Narkia

Serum 25-hydroxyvitamin D response to oral vitamin D intake in children -- Zittermann 7... - 0 views

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    Together, the earlier data and the data of Heaney et al indicate that an oral dose of vitamin D2 or vitamin D3 would lead to a comparable increase in circulating 25(OH)D concentrations in children and adults when the initial 25(OH)D3 concentrations in the groups are similar and when equivalent oral vitamin D doses expressed per kilogram body weight/d are given.

    Serum 25-hydroxyvitamin D response to oral vitamin D intake in children.
    Zittermann A.
    Am J Clin Nutr. 2003 Sep;78(3):496-7.
    PMID: 12936937
Matti Narkia

The same annual dose of 292 000 IU of vitamin D(3) (cholecalciferol) on either daily or... - 0 views

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    The same annual dose of 292 000 IU of vitamin D(3) (cholecalciferol) on either daily or four monthly basis for elderly women: 1-year comparative study of the effects on serum 25(OH)D(3) concentrations and renal function.
    Pekkarinen T, Välimäki VV, Aarum S, Turpeinen U, Hämäläinen E, Löyttyniemi E, Välimäki MJ.
    Clin Endocrinol (Oxf). 2009 May 25. [Epub ahead of print]
    PMID: 19486025
    DOI: 10.1111/j.1365-2265.2009.03637.x
Matti Narkia

Vitamin D and Cancer Mini-Symposium: The Risk of Additional Vitamin D - ScienceDirect -... - 0 views

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    Vitamin D and Cancer Mini-Symposium: The Risk of Additional Vitamin D.
    Vieth R.
    Ann Epidemiol. 2009 Apr 11. [Epub ahead of print]
    PMID: 19364661
    doi:10.1016/j.annepidem.2009.01.009   
Matti Narkia

Vitamin D supplementation during Antarctic winter. - Am J Clin Nutr. 2009 Ap - 0 views

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    Vitamin D supplementation during Antarctic winter.
    Smith SM, Gardner KK, Locke J, Zwart SR.
    Am J Clin Nutr. 2009 Apr;89(4):1092-8. Epub 2009 Feb 18.
    PMID: 19225122
    doi:10.3945/ajcn.2008.27189
Matti Narkia

Estimation of the dietary requirement for vitamin D in healthy adults. - 0 views

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    Estimation of the dietary requirement for vitamin D in healthy adults.\nCashman KD, Hill TR, Lucey AJ, Taylor N, Seamans KM, Muldowney S, Fitzgerald AP, Flynn A, Barnes MS, Horigan G, Bonham MP, Duffy EM, Strain JJ, Wallace JM, Kiely M.\nAm J Clin Nutr. 2008 Dec;88(6):1535-42.\nPMID: 19064513 [
Matti Narkia

Dose response to vitamin D supplementation among postmenopausal African American women.... - 0 views

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    Dose response to vitamin D supplementation among postmenopausal African American women.\nTalwar SA, Aloia JF, Pollack S, Yeh JK.\nAm J Clin Nutr. 2007 Dec;86(6):1657-62.\nPMID: 18065583
Matti Narkia

Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalcif... - 0 views

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    Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol.
    Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ.
    Am J Clin Nutr. 2003 Jan;77(1):204-10. Erratum in: Am J Clin Nutr. 2003 Nov;78(5):1047.
    PMID: 12499343
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