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Ola Play was so far totally available for Ola Select customers and the policy to spread to more than 50,000 Ola Prime vehicles by March 2017. Cab aggregator Ola on Friday drawn-out Ola Play, its in-car entertainment podium for ride-sharing, to all of its clients through Ola Prime Play classification. Launched in the month of ...

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology. Peterlik M, Cross HS. Eur J Clin Nutr. 2009 Dec;63(12):1377-86. Epub 2009 Sep 2. PMID: 19724293 doi:10.1038/ejcn.2009.105 A compromised vitamin D status, characterized by low 25-hydroxyvitamin D (25-(OH)D) serum levels, and a nutritional calcium deficit are widely encountered in European and North American countries, independent of age or gender. Both conditions are linked to the pathogenesis of many degenerative, malignant, inflammatory and metabolic diseases. Studies on tissue-specific expression and activity of vitamin D metabolizing enzymes, 25-(OH)D-1alpha-hydroxylase and 25-(OH)D-24-hydroxylase, and of the extracellular calcium-sensing receptor (CaR) have led to the understanding of how, in non-renal tissues and cellular systems, locally produced 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and extracellular Ca2+ act jointly as key regulators of cellular proliferation, differentiation and function. Impairment of cooperative signalling from the 1,25-(OH)2D3-activated vitamin D receptor (VDR) and from the CaR in vitamin D and calcium insufficiency causes cellular dysfunction in many organs and biological systems, and, therefore, increases the risk of diseases, particularly of osteoporosis, colorectal and breast cancer, inflammatory bowel disease, insulin-dependent diabetes mellitus type I, metabolic syndrome, diabetes mellitus type II, hypertension and cardiovascular disease. Understanding the underlying molecular and cellular processes provides a rationale for advocating adequate intake of vitamin D and calcium in all populations, thereby preventing many chronic diseases worldwide.

Do it yourself home improvement and diy repair at DoItYourself.com. Includes home improvement projects, hardware store, contractors, tools, Home Improvement how to, home repair, home repair projects, cleaning, stain removal, kitchen remodeling, plumbing,

Rhodiola rosea (Roseroot) is a plant in the family Crassulaceae that grows in cold regions of the world. These include much of the Arctic, the mountains of Central Asia, the Rocky Mountains, and mountainous parts of Europe, such as the Alps, Pyrenees, Car

NutriciónLa salud y buen funcionamiento de nuestro organismo, depende de la nutrición y alimentación que tengamos durante toda nuestra vida.  El cambio de dieta hacia alimentos poco saludables, con alto contenido de grasas, azúcar y sal, junto al sedentarismo, incrementan la obesidadObesida

When she was 14, Janna Leyde's father got into a close deadly car accident that changed her family's life. The accident resulted in traumatic brain damage that influenced her father emotionally and physically. What followed were years atypical of the normal American family life, characterized by her father's fraught and trauma with the challenges of recovery.

Vitamin D effective ultraviolet wavelengths due to scattering in shade. Turnbull DJ, Parisi AV, Kimlin MG. J Steroid Biochem Mol Biol. 2005 Sep;96(5):431-6. Epub 2005 Jul 6. PMID: 16005208