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Thromboxane A2 (TXA2) is a thromboxane. It is generated from prostaglandin H2 by thromboxane-A synthase. It is also a major component of blood clots. Aspirin irreversibly inhibits platelet cyclooxygenase 1 preventing the formation of prostaglandin H2, and therefore thromboxane A2. TXA2 is very unstable in aqueous solution, since it is hydrolyzed within about 30 seconds to the biologically inactive thromboxane B2. Due to its very short half life, TXA2 primarily functions as an autocrine or paracrine mediator in the nearby tissues surrounding its site of production.

beta-glucan A polysaccharide isolated from the cell walls of bacteria, plants, and fungi with immunostimulant and antineoplastic activities. In a solubilized form, beta-glucan binds to a lectin site within complement receptor 3 (CR3) on leukocytes, priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to complement 3 (iC3b)-coated tumors. Thus, the attachment of beta-glucan to CR3 of circulating leukocytes simulates leukocytes to kill iC3b-coated tumor cells in the same way as they kill iC3b-coated yeast. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

When you've got a busy schedule, healthy eating can seem more like a luxury than a necessity, like it is. To help you stay on track at work, during travel and even on the weekends, we've researched and discovered these 100 web tools. You'll be able to bookmark calorie calculators, instantly check portion sizes and nutrition information, connect with dieters and healthy eaters through social media sites, research recipes, and plenty more

The Official Web Site of Drs. Michael and Mary Dan Eades. Advocacy fo low carbohydrate diets.

Welcome to dietandcancerreport.org where you can find the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention. The most up to date reference and resource materials associated with both reports are available from this site

Welcome to the Arbor Nutrition Guide.\nEditor-in-chief: Dr.Tony Helman\nLast files updated 20 November 2005\n\nThis site has thousands of links, and not all of them are current.\nWe are engaged in a cycle of checking and updating them, section by section. \n\nYou can also enrol for the free Arbor Clinical Nutrition Updates, a regular, independent, concise report on the latest important research findings in nutrition.

The British Nutrition Foundation is a registered charity. It promotes the wellbeing of society through the impartial interpretation and effective dissemination of scientifically based knowledge and advice on the relationship between diet, physical activity and health\n\nThis site provides healthy eating information, resources for schools, news items, recipes and details of the work we undertake around the UK/EU.\n

The material presented on this site comes from individuals with years of hard-won experience either practicing alternative diets or observing those who do. As you'll find, no two writers will necessarily agree on all topics. A unifying theme, however, is the intent to squarely acknowledge and discuss the sometimes serious problems that can occur on alternative diets but often go unreported, and to go beyond the simplistic dogmas readily available elsewhere--in fact almost everywhere--to "explain them away." A sense of admirable idealism is often a motivating factor encouraging people to take responsibility for their own health and to explore different diets. However, the development of emotional attachments to philosophies underlying such diets can often end up becoming far more important for some individuals than the results they obtain--or fail to. One result has been widespread refusal in the alternative diet community to face health and behavioral problems that may arise on these diets. A common thread in what you'll read here is that a kind of subjective, "blinded naturalism" has become more or less endemic in the vegetarian, raw-food, and alternative diet movements, which can lead to serious health troubles.

Welcome to The Nutrition Source, a Web site maintained by the Department of Nutrition at the Harvard School of Public Health. In the What Should You Eat section, you'll find eight key tips for eating right, plus our bottom line recommendations on carbohydrates, protein, fats, fiber, vegetables and fruits, calcium and milk, alcohol, and vitamins. You can also learn more about a food pyramid that's actually based on the latest science: the Healthy Eating Pyramid, created by the Department of Nutrition at Harvard School of Public Health. A lot of confusing information about nutrition gets batted about in the media and on the Web. The Nutrition Source will cut through all that confusion, providing clear tips for healthy eating and dispelling a few nutrition myths along the way

Welcome to The Nutrition Source, a Web site maintained by the Department of Nutrition at the Harvard School of Public Health.

HerbMed® - an interactive, electronic herbal database - provides hyperlinked access to the scientific data underlying the use of herbs for health. It is an impartial, evidence-based information resource provided by the nonprofit Alternative Medicine Foundation, Inc. This public site provides access to the 20 most popular he

"Ann Arbor, MI - New laboratory research suggests that the COX-2 inhibitor celecoxib (Celebrex, Pfizer), might impede the action of "baby" aspirin [1]. Dr Gilad Rimon (University of Michigan, Ann Arbor) and colleagues found evidence that this was the case in a dog model and say that "it will be important to determine" whether the same is true in humans. The report was published online December 1, 2009 in the Proceedings of the National Academy of Medicine. Celecoxib is the only COX-2 inhibitor to have remained on the market in the US, and doctors who recommend this painkiller often coprescribe a daily low dose of 81 mg of aspirin (known as a "baby" dose) to counteract any possible prothrombotic effects of the coxib, while minimizing potential gastrointestinal toxicity of the aspirin. Senior author of the new work, Dr William L Smith (University of Michigan, Ann Arbor), explained to heartwire that previous studies in humans have shown that celecoxib does not interfere with the effect of a standard dose of aspirin (325 mg), but any potential interaction of celecoxib with the lower dose has not been examined. Stagger dosing to avoid any potential problems First, Smith explained that he and his colleagues looked in vitro at celecoxib and found that it binds to one of two available sites on the COX-1 enzyme. "This surprised us," he commented. "It appears to interfere with the ability of some other drugs to affect COX-1, most notably aspirin." Second, in beagles, they administered the dog-equivalent of a baby dose of aspirin in humans and then gave some of the animals the equivalent of 100 mg of celecoxib twice daily in addition. "Celecoxib plus aspirin interfered with the normal effect of low-dose aspirin on platelets," he notes. Smith says this observation obviously requires confirmation in humans, but in the meantime he suggests "getting around the problem" by patients taking the low-dose aspirin at least 15 to 30 minutes before the celecoxib is taken, "because

"This is for anyone researching goji berries, in the hope they'll come across this page, and not just accept the usual marketing page they come across. Goji berries are a great food. But they do not contain 500 times more Vitamin C than oranges, as is so often misleadingly claimed on marketing sites. Goji berries contain 2500mg/100g, while oranges contain 50mg/100g Vitamin C. That's 50 times more! Still a great food, but not quite what is claimed"

You may be asking yourself why a dermatologist-reviewed site from the American Academy of Dermatology (Academy) still says that diet does not cause acne. After all, haven't research studies found that certain foods cause acne? If you have acne, you may even have noticed that when you eat certain foods you break out. With all this evidence, why does the Academy still say that food does not cause acne

Cool site that provides information on a combination of factors on health guide this includes Conditions amp; Diseases,Drugs amp; Health

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"We are aware of substantial scientific evidence supporting the role of vitamin D in prevention of cancer. It has been reasonably established that adequate serum vitamin D metabolite levels are associated with substantially lower incidence rates of several types of cancer, including those of the breast, colon, and ovary, and other sites. We have concluded that the vitamin D status of most individuals in North America will need to be greatly improved for substantial reduction in incidence of cancer. Epidemiological studies have shown that higher vitamin D levels are also associated with lower risk of Type I diabetes in children and of multiple sclerosis. Several studies have found that markers of higher vitamin D levels are associated with lower incidence and severity of influenza and several other infectious diseases."

When I wrote the Overcoming the Curse of the Mummies chapter in Protein Power, I wrote mainly about the evidence of disease found in the mummies of ancient Egyptians and correlated this disease with their high-carbohydrate diet. Along with all the material on mummies, which is the part everyone seems to remember, I wrote about a study done in the United States in the 1970s that persuasively demonstrated the superiority of the hunter diet as compared to an agricultural diet, which no one seems to remember. I came across that study a couple of days ago and decided to present it in a little more detail than I was able to in Protein Power. The anthropological record of early man clearly shows health took a nosedive when populations made the switch from hunting and gathering to agriculture. It takes a physical anthropologist about two seconds to look at a skeleton unearthed from an archeological site to tell if the owner of that skeleton was a hunter-gatherer or an agriculturist.