Skip to main content

Home/ Nutrition/ Group items tagged Diabetes cvd

Rss Feed Group items tagged

Matti Narkia

Sugar May Be Bad, But This Sweetener Is Far More Deadly, Part 1 of 3 - 4 views

  •  
    "Scientists have proved for the first time that fructose, a cheap form of sugar used in thousands of food products and soft drinks, can damage human metabolism and is fueling the obesity crisis.

    Fructose, a sweetener usually derived from corn, can cause dangerous growths of fat cells around vital organs and is able to trigger the early stages of diabetes and heart disease.

    Over 10 weeks, 16 volunteers on a controlled diet including high levels of fructose produced new fat cells around their heart, liver and other digestive organs. They also showed signs of food-processing abnormalities linked to diabetes and heart disease. Another group of volunteers on the same diet, but with glucose sugar replacing fructose, did not have these problems."
Matti Narkia

Nutritional diseases - modern-diets-and-nutritional-diseases.com - 0 views

  •  
    "What Are Nutritional Diseases?

    In their book, The Modern Nutritional Diseases, Fred and Alice Ottoboni, retired Public Health Service scientists, list the following.
    * Obesity
    * Diabetes II
    * Cardiovascular Diseases
    * Stroke.
    * Cancer.

    Modern nutritional diseases are just that. They haven't always been the ugly part of our life. They were introduced when people had to get their food from grocery stores, when people traded their whole foods from the family farm for those manufactured by the food processing industry. "
Matti Narkia

Unexpected Perks of Coffee Consumption - The Early Show - CBS News - 0 views

  •  
    "(CBS) Your daily cup of java may deliver some unexpected health benefits. Studies have shown it may lower your risk for Type II diabetes and certain types of cancer (colon, mouth and throat), and protect against heart disease and cavities.

    Dr. Alanna Levine, a primary care physician, said on "The Early Show" researchers aren't sure exactly why coffee has these benefits, but speculated that perhaps the coffee has antioxidant properties. "
Matti Narkia

Overview and perspective in human nutrition. Willett WC. - Asia Pac J Clin Nutr. 2008; - 0 views

  •  
    Overview and perspective in human nutrition.
    Willett WC.
    Asia Pac J Clin Nutr. 2008;17 Suppl 1:1-4. Review.
    PMID: 18296289

    For the last decade, the focus of nutritional advice for prevention of chronic disease has been to limit or reduce
    total fat intake and to consume large amounts of carbohydrate. However, this advice is inconsistent with many
    lines of evidence indicating that unsaturated fats have beneficial metabolic effects and reduce risk of coronary
    heart disease. More recent evidence has also shown that the large majority of carbohydrates in Western diets,
    consisting of refined starches and sugars, have adverse metabolic effects and increase risks of coronary heart
    disease and type 2 diabetes. Unfortunately, a major opportunity for health improvement has been lost by failing
    to distinguish healthy from unhealthy forms of carbohydrates and fats. Recent analyses indicate that moderate
    changes in diet, together with regular physical activity and not smoking, can prevent the large majority of heart
    disease, type 2 diabetes, and some forms of cancer. These findings have substantial relevance for many populations
    in Asia, where incidence of type 2 diabetes is rising rapidly.
Matti Narkia

Quality of HDL differs in diabetics but improves with niacin therapy - theheart.org - 1 views

  •  
    "Quality of HDL differs in diabetics but improves with niacin therapy
    December 22, 2009 | Michael O'Riordan

    Hannover, Germany - A small study published this week hints that the effects of HDL cholesterol differ in healthy patients from those with diabetes mellitus [1]. HDL cholesterol in individuals with diabetes has impaired endothelial protective functions compared with the HDL from healthy subjects, although treatment with extended-release niacin can improve these endothelial protective effects, according to researchers.

    Publishing their findings online December 21, 2009 in Circulation, lead investigator Dr Sajoscha Sorrentino (Hannover Medical School, Germany) and colleagues write that because recent HDL-raising intervention studies have yielded mixed results, "circulating HDL-cholesterol levels alone likely do not represent an adequate measure of therapeutic efficacy, and indexes of HDL functionality are urgently needed for assessment of the potential of HDL-targeted therapies to exert vasoprotective effects."

    Speaking with heartwire, senior investigator Dr Ulf Landmesser (University of Zürich, Switzerland), said the results have implications for clinical research.

    "We have to understand that we can't look only at the HDL levels in the plasma, but we need to look at the quality," he said. "The quality of the HDL is not the same in different patients. This is very important for targeting HDL as a treatment. Second, niacin therapy is a promising way not only to raise HDL but also to improve the quality; it is a good treatment option, especially if the larger outcomes data are positive.""
Matti Narkia

Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients... - 0 views

  •  
    Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients With Type 2 Diabetes Mellitus but Are Improved After Extended-Release Niacin Therapy.
    Sorrentino SA, Besler C, Rohrer L, Meyer M, Heinrich K, Bahlmann FH, Mueller M, Horváth T, Doerries C, Heinemann M, Flemmer S, Markowski A, Manes C, Bahr MJ, Haller H, von Eckardstein A, Drexler H, Landmesser U.
    Circulation. 2009 Dec 21. [Epub ahead of print]
    PMID: 20026785
    doi: 10.1161/CIRCULATIONAHA.108.836346

    Conclusions-HDL from patients with type 2 diabetes mellitus and metabolic syndrome has substantially impaired endothelial-protective effects compared with HDL from healthy subjects. ER niacin therapy not only increases HDL plasma levels but markedly improves endothelial-protective functions of HDL in these patients, which is potentially more important.
Matti Narkia

NEJM -- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reacti... - 0 views

  •  
    Conclusions In this trial of apparently healthy persons without hyperlipidemia but with elevated high-sensitivity C-reactive protein levels, rosuvastatin significantly reduced the incidence of major cardiovascular events. \n\nRosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.\nRidker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group.\nN Engl J Med. 2008 Nov 20;359(21):2195-207. Epub 2008 Nov 9.\nPMID: 18997196
Matti Narkia

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pa... - 0 views

  •  
    Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology.
    Peterlik M, Cross HS.
    Eur J Clin Nutr. 2009 Dec;63(12):1377-86. Epub 2009 Sep 2.
    PMID: 19724293
    doi:10.1038/ejcn.2009.105

    A compromised vitamin D status, characterized by low 25-hydroxyvitamin D (25-(OH)D) serum levels, and a nutritional calcium deficit are widely encountered in European and North American countries, independent of age or gender. Both conditions are linked to the pathogenesis of many degenerative, malignant, inflammatory and metabolic diseases. Studies on tissue-specific expression and activity of vitamin D metabolizing enzymes, 25-(OH)D-1alpha-hydroxylase and 25-(OH)D-24-hydroxylase, and of the extracellular calcium-sensing receptor (CaR) have led to the understanding of how, in non-renal tissues and cellular systems, locally produced 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and extracellular Ca2+ act jointly as key regulators of cellular proliferation, differentiation and function. Impairment of cooperative signalling from the 1,25-(OH)2D3-activated vitamin D receptor (VDR) and from the CaR in vitamin D and calcium insufficiency causes cellular dysfunction in many organs and biological systems, and, therefore, increases the risk of diseases, particularly of osteoporosis, colorectal and breast cancer, inflammatory bowel disease, insulin-dependent diabetes mellitus type I, metabolic syndrome, diabetes mellitus type II, hypertension and cardiovascular disease. Understanding the underlying molecular and cellular processes provides a rationale for advocating adequate intake of vitamin D and calcium in all populations, thereby preventing many chronic diseases worldwide.
Matti Narkia

Fish intake is associated with a reduced progression of coronary artery ather... - 0 views

  •  
    Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease.
    Erkkilä AT, Lichtenstein AH, Mozaffarian D, Herrington DM.
    Am J Clin Nutr. 2004 Sep;80(3):626-32.
    PMID: 15321802

    Conclusions: Consumption of fish is associated with a significantly reduced progression of coronary artery atherosclerosis in women with coronary artery disease.
Matti Narkia

Efficacy of Berberine in Patients with Type 2 Diabetes - 0 views

  •  
    Efficacy of berberine in patients with type 2 diabetes mellitus.
    Yin J, Xing H, Ye J.
    Metabolism. 2008 May;57(5):712-7.
    PMID: 18442638
    doi: 10.1016/j.metabol.2008.01.013.

    Fasting plasma insulin and homeostasis model assessment of insulin resistance index were reduced by 28.1% and 44.7% (P<.001), respectively. Total cholesterol and low-density lipoprotein cholesterol were decreased significantly as well. During the trial, 20 (34.5%) patients experienced transient gastrointestinal adverse effects. Functional liver or kidney damages were not observed for all patients. In conclusion, this pilot study indicates that berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism

    In summary, that berberine is a potent oral hypoglycemic agent with modest effect on lipid metabolism. It is safe and the cost of treatment by berberine is very low. It may serve as a new drug candidate in the treatment of type 2 diabetes. However, this is a pilot study. The efficacy of berberine needs to be tested in a much larger population and characterized as a function of the known duration of the diabetes. Further studies are needed to evaluate the action of berberine on type 2 diabetes in other ethnic groups.
Matti Narkia

Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine... - 0 views

  •  
    Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
    Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning G.
    J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65. Epub 2008 Apr 8.
    PMID: 18397984
    doi:10.1210/jc.2007-2404

    Conclusions: Berberine is effective and safe in the treatment of type 2 diabetes and dyslipidemia.
Matti Narkia

Berberine - wellness.com - 0 views

  •  
    "Berberine is a bitter-tasting, yellow, plant alkaloid with a long history of medicinal use in Chinese and Ayurvedic medicine. Berberine is present in the roots, rhizomes and stem bark of various plants including Hydrastis canadensis (goldenseal), Coptis chinensis (coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (tree turmeric). Berberine has also been used historically as a dye, due to its yellow color.
    Clinical trials have been conducted using berberine. There is some evidence to support its use in the treatment of trachomas (eye infections), bacterial diarrhea, and leishmaniasis (parasitic disease). Berberine has also shown antimicrobial activity against bacteria, viruses, fungi, protozoans, helminths (worms), and chlamydia (STD). Future clinical research is warranted in these areas, as well as cardiovascular disease, skin disorders, and liver disorders.
    Berberine has been shown to be safe in the majority of clinical trials. However, there is a potential for interaction between berberine and many prescription medications, and berberine should not be used by pregnant or breastfeeding women, due to potential for adverse effects in the newborn."
Matti Narkia

Berberine - Wikipedia, the free encyclopedia - 0 views

  •  
    "Berberine is a quaternary ammonium salt from the group of isoquinoline alkaloids. It is found in such plants as Berberis, goldenseal (Hydrastis canadensis), and Coptis chinensis, usually in the roots, rhizomes, stems, and bark. Berberine is strongly yellow colored, which is why in earlier times berberis species were used to dye wool, leather and wood. Wool is still today dyed with berberine in Northern India

    Berberine (BBR) is a natural compound with up-regulating activity on both low-density-lipoprotein receptor (LDLR) and insulin receptor (InsR). This one-drug-multiple-target characteristic might be suitable for the treatment of metabolic syndrome.[12] Berberine has been tested and used successfully in experimental[13] and human diabetes mellitus.[14][15][16] Berberine has been shown to lower elevated blood glucose as effectively as metformin.[17] The mechanisms include inhibition of aldose reductase,[18] inducing glycolysis,[19] preventing insulin resistance[20] through increasing insulin receptor expression[14] and acting like incretins.

    Berberine has drawn extensive attention towards its antineoplastic effects.[43][44] It seems to suppress the growth of a wide variety of tumor cells including breast cancer,[45] leukemia, melanoma,[46] epidermoid carcinoma, hepatoma, oral carcinoma, tongue carcinoma,[47] glioblastoma, prostate carcinoma, gastric carcinoma.[48][49] Animal studies have shown that berberine can suppress chemical-induced carcinogenesis, tumor promotion, tumor invasion,[50][51][52][53][54] prostate cancer,[55][56][57][58] neuroblastoma,[59][60] and leukemia.[34][61] It is a radiosensitzer of tumor cells but not of normal cells
Matti Narkia

Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty aci... - 0 views

  •  
    Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty acids.
    Ohman M, Akerfeldt T, Nilsson I, Rosen C, Hansson LO, Carlsson M, Larsson A.
    Ups J Med Sci. 2008;113(3):315-23.P
    MID: 18991244

    Today, eggs with an increased content of -3 fatty acids are available but there are few publications on the effects of consumption of such eggs on the lipoproteins and acute phase markers in humans. The aim of the present study was to evaluate the effects of consumption of standard eggs and -3 enriched eggs on lipoproteins, glucose and inflammation markers. Nineteen healthy volunteers consumed one extra egg per day of either standard eggs or omega-3 enriched eggs in a double-blind, cross-over study. The duration of each period was 1 month. The effects of the different egg diets on apolipoprotein A1 and B (Apo A1 and B), lipoprotein (a), creatinine, cystatin C, C-reactive protein, serum amyloid protein A, interleukin 6, triglycerides, glucose, total-, high-density lipoprotein and low-density lipo-protein cholesterol concentrations were analyzed. Addition of one regular egg per day to the normal diet had no negative impact on blood lipids or inflammation markers. Consumption of omega-3 enriched eggs resulted in higher levels of ApoA1, lower ApoB/ApoA1 ratio and lower plasma glucose. These effects have been associated in previous studies with a reduced risk for cardiovascular mortality and diabetes.
Matti Narkia

Coenzyme Q10 - September 15, 2005 - American Family Physician - 0 views

  •  
    Coenzyme Q10.
    Bonakdar RA, Guarneri E.
    Am Fam Physician. 2005 Sep 15;72(6):1065-70. Review.
    PMID: 16190504

    Coenzyme Q10 is a vitamin-like substance used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders such as Parkinson's disease and certain encephalomyopathies for which coenzyme Q10 has gained orphan drug status. Results in other areas of research, including treatment of congestive heart failure and diabetes, appear to be contradictory or need further clarification before proceeding with recommendations. Coenzyme Q10 appears to be a safe supplement with minimal side effects and low drug interaction potential.
Matti Narkia

Coenzyme Q10 - umm.edu - 0 views

  •  
    "Coenzyme Q10 (CoQ10) is a compound found naturally in the energy-producing center of the cell known as the mitochondria. CoQ10 is involved in the making of an important molecule known as adenosine triphosphate (ATP). ATP serves as the cell's major energy source and drives a number of biological processes including muscle contraction and the production of protein. CoQ10 also works as an antioxidant."
Matti Narkia

Mediterranean Diet Helps Control Diabetes - 0 views

  •  
    "Aug. 31, 2009 -- Eating a Mediterranean-style diet may help people with type 2 diabetes keep their disease under control without drugs better than following a typical low-fat diet.

    A new study from Italy shows that people with type 2 diabetes who ate a Mediterranean diet rich in vegetables and whole grains with at least 30% of daily calories from fat (mostly olive oil) were better able to manage their disease without diabetes medications than those who ate a low-fat diet with no more than 30% of calories from fat (with less than 10% coming from saturated fat choices).

    After four years, researchers found that 44% of people on the Mediterranean diet ended up requiring diabetes medications to control their blood sugars compared with 70% of those who followed the low-fat diet.

    It's one of the longest-term studies of its kind, and researchers, including Katherine Esposito, MD, of the Second University of Naples, say the results "reinforce the message that benefits of lifestyle interventions should not be overlooked.""
Matti Narkia

Effects of a Mediterranean-Style Diet on the Need for Antihyperglycemic Drug Therapy in... - 0 views

  •  
    Effects of a Mediterranean-style diet on the need for antihyperglycemic drug therapy in patients with newly diagnosed type 2 diabetes: a randomized trial.
    Esposito K, Maiorino MI, Ciotola M, Di Palo C, Scognamiglio P, Gicchino M, Petrizzo M, Saccomanno F, Beneduce F, Ceriello A, Giugliano D.
    Ann Intern Med. 2009 Sep 1;151(5):306-14. Erratum in: Ann Intern Med. 2009 Oct 20;151(8):591.
    PMID: 19721018

    Conclusion: Compared with a low-fat diet, a low-carbohydrate, Mediterranean-style diet led to more favorable changes in glycemic control and coronary risk factors and delayed the need for antihyperglycemic drug therapy in overweight patients with newly diagnosed type 2 diabetes.
Matti Narkia

One-Year Comparison of a High-Monounsaturated Fat Diet With a High-Carbohydrate Diet in... - 0 views

  •  
    One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes.
    Brehm BJ, Lattin BL, Summer SS, Boback JA, Gilchrist GM, Jandacek RJ, D'Alessio DA.
    Diabetes Care. 2009 Feb;32(2):215-20. Epub 2008 Oct 28.
    PMID: 18957534
    doi: 10.2337/dc08-0687

    CONCLUSIONS-In individuals with type 2 diabetes, high-MUFA diets are an alternative to conventional lower-fat, high-CHO diets with comparable beneficial effects on body weight, body composition, cardiovascular risk factors, and glycemic control.
Matti Narkia

A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in i... - 0 views

  •  
    A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease.
    Lindeberg S, Jönsson T, Granfeldt Y, Borgstrand E, Soffman J, Sjöström K, Ahrén B.
    Diabetologia. 2007 Sep;50(9):1795-807. Epub 2007 Jun 22.
    PMID: 17583796
    DOI: 10.1007/s00125-007-0716-y

    Conclusions/interpretation A Palaeolithic diet may improve glucose tolerance independently of decreased waist circumference.
1 - 20 of 47 Next › Last »
Showing 20 items per page