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Matti Narkia

Boswellic acid - Wikipedia, the free encyclopedia - 0 views

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    Boswellic acids are a series of pentacyclic triterpene molecules which are produced by plants in the genus Boswellia. Like many other terpenes, boswellic acids appear in the resin of the plant which exudes them; it is estimated that they make up 30% of the resin of Boswellia serrata
Matti Narkia

Synergistic anti-inflammatory effects of low doses of curcumin in combination with poly... - 0 views

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    Synergistic anti-inflammatory effects of low doses of curcumin in combination with polyunsaturated fatty acids: docosahexaenoic acid or eicosapentaenoic acid.
    Saw CL, Huang Y, Kong AN.
    Biochem Pharmacol. 2010 Feb 1;79(3):421-30. Epub 2009 Sep 8.
    PMID: 19744468
Matti Narkia

Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 f... - 0 views

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    Mice fed fish oil and curcumin showed a significantly reduced tumor volume, 25% (P < 0.04) and 43% (P < 0.005), respectively, and importantly, a combination of curcumin and fish oil diet showed > 72% (P < 0.0001) tumor volume reduction. Expression and activity of iNOS, COX-2, and 5-LOX are downregulated, and p21 is upregulated in tumor xenograft fed curcumin combined with fish oil diet when compared to individual diets. The preceding results evidence for the first time that curcumin combined with omega-3 fatty acids provide synergistic pancreatic tumor inhibitory properties.

    Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids.
    Swamy MV, Citineni B, Patlolla JM, Mohammed A, Zhang Y, Rao CV.
    Nutr Cancer. 2008;60 Suppl 1:81-9.
    PMID: 19003584
Matti Narkia

Eating Your Way to Prostate Cancer - Life Extension - 0 views

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    A plethora of research documents the role of chronic inflammatory mediators such as 5-lipooxygenase (5-LOX) and tumor necrosis factor-alpha (TNF-α) in the manifestation and progression of prostate and other cancers.7-19,30,31,33,49,52-54,87,88

    The typical American diet is high in omega-6 fatty acids, saturated fats, and arachidonic acid. Over-consumption of these foods, and under-consumption of omega-3 fatty acids, contribute significantly to systemic chronic inflammatory states.

    Boswellia extracts have been thoroughly studied as natural remedies for inflammatory disorders. A patented extract from boswellia called 5-LOXIN® has potent ability to inhibit the enzyme 5-LOX, preventing the formation of protein-degrading enzymes, and protecting against inflammation-induced events that can promote tumor angiogenesis.
Matti Narkia

Targeting lipoxygenases with care. - ScienceDirect - Chemistry & Biology 2006 Nov - 0 views

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    Targeting lipoxygenases with care.
    de Souza PM, Newson J, Gilroy DW.
    Chem Biol. 2006 Nov;13(11):1121-2.
    PMID: 17113992
    doi:10.1016/j.chembiol.2006.11.002  
Matti Narkia

Controlling the resolution of acute inflammation: a new genus of dual anti-inflammatory... - 0 views

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    Controlling the resolution of acute inflammation: a new genus of dual anti-inflammatory and proresolving mediators.
    Serhan CN.
    J Periodontol. 2008 Aug;79(8 Suppl):1520-6. Review.
    PMID: 18673006
    doi:10.1902/jop.2008.080231
Matti Narkia

Resolvin E2: Identification and Anti-Inflammatory Actions: Pivotal Role of Human 5-Lipo... - 0 views

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    Resolvin E2: identification and anti-inflammatory actions: pivotal role
    of human 5-lipoxygenase in resolvin E series biosynthesis.
    Tjonahen E, Oh SF, Siegelman J, Elangovan S, Percarpio KB, Hong S,
    Arita M, Serhan CN.
    Chem Biol. 2006 Nov;13(11):1193-202.
    PMID: 17114001
    doi:10.1016/j.chembiol.2006.09.011
Matti Narkia

Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins. - Bentham Science Publi... - 0 views

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    Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
    Romano M.
    Inflamm Allergy Drug Targets. 2006 Apr;5(2):81-90. Review.
    PMID: 16613567
Matti Narkia

The role of eicosanoids in the brain. [Asia Pac J Clin Nutr. 2008] - PubMed Result - 0 views

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    The role of eicosanoids in the brain.
    Tassoni D, Kaur G, Weisinger RS, Sinclair AJ.
    Asia Pac J Clin Nutr. 2008;17 Suppl 1:220-8. Review.
    PMID: 18296342

    Liberation of these PUFA from the phosphoglycerides occurs via the action of specific phospholipases (PLA2).
Matti Narkia

Eicosanoid - Wikipedia, the free encyclopedia - 0 views

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    In biochemistry, eicosanoids are signaling molecules derived from omega-3 (ω-3) or omega-6 (ω-6) fats. They exert complex control over many bodily systems, especially in inflammation, immunity and as messengers in the central nervous system. The network
Matti Narkia

Arachidonate 5-lipoxygenase - Wikipedia, the free encyclopedia - 0 views

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    Arachidonate 5-lipoxygenase (5-lipoxygenase, 5-LO, 5-LOX or Alox5), which transforms EFAs into leukotrienes, is a current target for pharmaceutical intervention in a number of diseases. 5-LO is a target for pharmaceutical intervention in CAD.
Matti Narkia

5-Loxin®, 75 Mg 100 Vegetarian Capsules - 0 views

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    5-LOX inhibitor supplement based on Boswellia - from LEF.
Matti Narkia

Eating Your Way to Prostate Cancer By William Faloon - LEF Magazine - 0 views

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    Prostate cancer prevention and treatment by nutrition and supplements.
    LEF Magazine February 2007.
Matti Narkia

Overexpression of 5-Lipoxygenase and Cyclooxygenase 2 in Hamster and Human Oral Cancer ... - 0 views

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    Li N, Sood S, Wang S, Fang M, Wang P, Sun Z, Yang CS, Chen X.
    Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
    Clin Cancer Res. 2005 Mar 1;11(5):2089-96.
    PMID
Matti Narkia

Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz... - 0 views

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    Sun Z, Sood S, Li N, Ramji D, Yang P, Newman RA, Yang CS, Chen X.
    Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinoge
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