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Matti Narkia

Researchers link calorie intake to cell lifespan, cancer development (w/ Video) - 0 views

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    "Researchers from the University of Alabama at Birmingham (UAB) have discovered that restricting consumption of glucose, the most common dietary sugar, can extend the life of healthy human-lung cells and speed the death of precancerous human-lung cells, reducing cancer's spread and growth rate.

    The research has wide-ranging potential in age-related science, including ways in which calorie-intake restriction can benefit longevity and help prevent diseases like cancer that have been linked to aging, said principal investigator Trygve Tollefsbol, Ph.D., D.O., a professor in the Department of Biology.

    "These results further verify the potential health benefits of controlling calorie intake." Tollefsbol said. "Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body's natural ability to kill off cancer-forming cells.
Matti Narkia

Calorie intake linked to cell lifespan, cancer development - 0 views

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    "ScienceDaily (Dec. 17, 2009) - Researchers from the University of Alabama at Birmingham (UAB) have discovered that restricting consumption of glucose, the most common dietary sugar, can extend the life of healthy human-lung cells and speed the death of precancerous human-lung cells, reducing cancer's spread and growth rate.

    The research has wide-ranging potential in age-related science, including ways in which calorie-intake restriction can benefit longevity and help prevent diseases like cancer that have been linked to aging, said principal investigator Trygve Tollefsbol, Ph.D., D.O., a professor in the Department of Biology.

    "These results further verify the potential health benefits of controlling calorie intake." Tollefsbol said. "Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body's natural ability to kill off cancer-forming cells.""
Matti Narkia

Fish, Vitamin D, and Flavonoids in Relation to Renal Cell Cancer Among Smokers -- Wilso... - 0 views

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    Fish, vitamin D, and flavonoids in relation to renal cell cancer among smokers.
    Wilson RT, Wang J, Chinchilli V, Richie JP, Virtamo J, Moore LE, Albanes D.
    Am J Epidemiol. 2009 Sep 15;170(6):717-29. Epub 2009 Aug 3.
    PMID: 19651663
    doi:10.1093/aje/kwp178

    These results suggest that the flavonoid quercetin may prevent renal cell cancer among male smokers. The possible risk associated with fish intake warrants further investigation before conclusions may be drawn.
Matti Narkia

The Heart Scan Blog: Small LDL: Perfect index of carbohydrate intake - 0 views

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    "Measuring the number of small LDL particles is the best index of carbohydrate intake I know of, better than even blood sugar and triglycerides.

    In other words, increase carbohydrate intake and small LDL particles increase. Decrease carbohydrates and small LDL particles decrease.

    Why?

    Carbohydrates increase small LDL via a multistep process:

    First step: Increased fatty acid and apoprotein B production in the liver, which leads to increased VLDL production. (Apoprotein B is the principal protein of VLDL and LDL)

    Second step: Greater VLDL availability causes triglyceride-rich VLDL to interact with other particles, namely LDL and HDL, enriching them in triglycerides (via the action of cholesteryl-ester transfer protein, or CETP). Much VLDL is converted to LDL.

    Third step: Triglyceride-rich LDL is "remodeled" by enzymes like hepatic lipase, which create small LDL"
Matti Narkia

Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-... - 0 views

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    Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study.
    Kim J, Lim SY, Shin A, Sung MK, Ro J, Kang HS, Lee KS, Kim SW, Lee ES.
    BMC Cancer. 2009 Jun 30;9:216.
    PMID: 19566923
    doi: 10.1186/1471-2407-9-216

    Conclusion
    These results suggest that high consumption of fatty fish is associated with a reduced risk for breast cancer, and that the intake of omega-3 fatty acids from fish is inversely associated with postmenopausal breast cancer risk
Matti Narkia

A comparison of egg consumption with other modifiable coronary heart disease lifestyle ... - 0 views

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    A comparison of egg consumption with other modifiable coronary heart disease lifestyle risk factors: a relative risk apportionment study.
    Barraj L, Tran N, Mink P.
    Risk Anal. 2009 Mar;29(3):401-15. Epub 2008 Nov 4.
    PMID: 19000074
    DOI: 10.1111/j.1539-6924.2008.01149.x

    Guidelines from the American Heart Association (AHA) recommend that healthy adults limit their intake of dietary cholesterol to less than 300 mg per day. Since a large egg contains about 71% of that amount, the AHA recommends restricting egg consumption unless dietary cholesterol intakes from other sources are limited. We applied a risk apportionment approach to estimate the contribution of egg consumption and other modifiable lifestyle risk factors (e.g., smoking, poor diet, minimal exercise, and alcohol intake) to coronary heart disease (CHD) risk at the population level. Specifically, we categorized the U.S. adult population ages 25+ into distinct risk groups based on the prevalence of modifiable lifestyle risk factors and applied an apportionment model, typically used to assess risk contribution at the individual level, to estimate the contribution of egg intake to CHD risk. Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for <1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.
Matti Narkia

Meat, eggs, dairy products, and risk of breast cancer in the European Prospective Inves... - 0 views

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    Meat, eggs, dairy products, and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
    Pala V, Krogh V, Berrino F, Sieri S, Grioni S, Tjønneland A, Olsen A, Jakobsen MU, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Romieu I, Linseisen J, Rohrmann S, Boeing H, Steffen A, Trichopoulou A, Benetou V, Naska A, Vineis P, Tumino R, Panico S, Masala G, Agnoli C, Engeset D, Skeie G, Lund E, Ardanaz E, Navarro C, Sánchez MJ, Amiano P, Svatetz CA, Rodriguez L, Wirfält E, Manjer J, Lenner P, Hallmans G, Peeters PH, van Gils CH, Bueno-de-Mesquita HB, van Duijnhoven FJ, Key TJ, Spencer E, Bingham S, Khaw KT, Ferrari P, Byrnes G, Rinaldi S, Norat T, Michaud DS, Riboli E.
    Am J Clin Nutr. 2009 Sep;90(3):602-12. Epub 2009 Jun 2.
    PMID: 19491385
    doi:10.3945/ajcn.2008.27173

    Conclusions: We have not consistently identified intakes of meat, eggs, or dairy products as risk factors for breast cancer. Future studies should investigate the possible role of high-temperature cooking in the relation of red meat intake with breast cancer risk.
Matti Narkia

Meat and egg consumption and risk of breast cancer among Chinese women. - Cancer Causes... - 0 views

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    Meat and egg consumption and risk of breast cancer among Chinese women.
    Zhang CX, Ho SC, Chen YM, Lin FY, Fu JH, Cheng SZ.
    Cancer Causes Control. 2009 Jun 17. [Epub ahead of print]
    PMID: 19533390

    Conclusions This study suggested that processed meat intake was associated with a possible increased risk of breast cancer. There was no significant association between consumption of total and red meat, poultry, fish, or egg with breast cancer risk
Matti Narkia

Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in... - 0 views

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    Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in older adults with low macular pigment taking cholesterol-lowering statins.
    Vishwanathan R, Goodrow-Kotyla EF, Wooten BR, Wilson TA, Nicolosi RJ.
    Am J Clin Nutr. 2009 Nov;90(5):1272-9. Epub 2009 Sep 16.
    PMID: 19759170

    Conclusions: Consumption of 4 egg yolks/d, and possibly of 2 egg yolks/d, for 5 wk benefited macular health in older adults with low MPOD. Serum HDL cholesterol increased without an increase in LDL cholesterol in this study population, most of whom were taking cholesterol-lowering statins.
Matti Narkia

Egg Consumption and Risk of Type 2 Diabetes in Men and Women - Diabetes Care - 0 views

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    Egg consumption and risk of type 2 diabetes in men and women.
    Djoussé L, Gaziano JM, Buring JE, Lee IM.
    Diabetes Care. 2009 Feb;32(2):295-300. Epub 2008 Nov 18.
    PMID: 1901777
    doi: 10.2337/dc08-1271

    RESULTS-During mean follow-up of 20.0 years in men and 11.7 years in women, 1,921 men and 2,112 women developed type 2 diabetes. Compared with no egg consumption, multivariable adjusted hazard ratios for type 2 diabetes were 1.09 (95% CI 0.87-1.37), 1.09 (0.88-1.34), 1.18 (0.95-1.45), 1.46 (1.14-1.86), and 1.58 (1.25-2.01) for consumption of <1, 1><0.0001). hazard multivariable women ratios 1 were for corresponding><0.0001).

    CONCLUSIONS-These data suggest that high levels of egg consumption (daily) are associated with an increased risk of type 2 diabetes in men and women. Confirmation of these findings in other populations is warranted.
Matti Narkia

Association Between Type of Dietary Fish and Seafood Intake and the Risk of Incident Ty... - 0 views

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    Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.
    Patel PS, Sharp SJ, Luben RN, Khaw KT, Bingham SA, Wareham NJ, Forouhi NG.
    Diabetes Care. 2009 Oct;32(10):1857-63. Epub 2009 Jul 10.
    PMID: 19592633
    doi: 10.2337/dc09-0116

    CONCLUSIONS Total, white, and oily fish consumption may be beneficial for reducing risk of diabetes, reinforcing the public health message to consume fish regularly. Greater shellfish intake seems to be associated with an increased risk of diabetes, warranting further investigation into cooking methods and mechanisms.

    In summary, we report that specific types of fish intake are differentially associated with the risk of diabetes. Total intake of both white fish and oily fish was associated with a lower risk of diabetes, reinforcing the public health message to consume fish regularly. Shellfish intake was associated with an increased risk of diabetes, which highlights the potential importance of seafood preparation and cooking methods. The increased risk of diabetes with shellfish intake requires further study.
Matti Narkia

High salt intake boosts stroke, CVD risk - theheart.org - 0 views

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    "November 25, 2009 | Susan Jeffrey

    Naples, Italy - A new meta-analysis confirms that high salt intake is associated with increased risks of stroke and total cardiovascular disease (CVD) [1].

    The pooled relative risk showed that an average difference of about 5 g of salt per day was associated with a 23% increased risk of stroke, the researchers report, and a 17% increase in CVD risk. The average habitual salt intake in most Western countries is 10 g per day, double the level currently recommended by the World Health Organization.

    "Given that the case-fatality rate for stroke is estimated at one in three, and that for total cardiovascular disease at one in five, a 23% reduction in the rate of stroke and a 17% overall reduction in the rate of cardiovascular disease attributable to a reduction in population salt intake could avert some one and a quarter million deaths from stroke, and almost three million deaths from cardiovascular disease each year," the researchers, with lead author Dr Pasquale Strazzullo (University of Naples Medical School, Italy), conclude.

    Moreover, because of some imprecision in salt-intake measurements in these cohort studies, the actual effects are likely to be underestimated, they add.

    The study was published online November 24, 2009 in the British Medical Journal."
Matti Narkia

Doctors debate vitamin D levels - 0 views

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    The Standing Committee of European Doctors (CPME) is preparing a vitamin D policy paper it hopes can influence European national associations considering vitamin D medical recommendations.

    PA International Foundation is hosting an event on the topic in Bruges, Belgium, on October 6, its 14th workshop to be held on the matter. The CPME draft paper will be presented at the convention attended by doctors, scientists, patient groups, media representatives and politicians.
Matti Narkia

Dietary vitamin D and cancers of the oral cavity and esophagus -- Lipworth et al. 20 (9... - 0 views

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    Dietary vitamin D and cancers of the oral cavity and esophagus.
    Lipworth L, Rossi M, McLaughlin JK, Negri E, Talamini R, Levi F, Franceschi S, La Vecchia C.
    Ann Oncol. 2009 Sep;20(9):1576-81. Epub 2009 Jun 1.
    PMID: 19487490

    Conclusion: We observed inverse associations between dietary vitamin D intake and risk of SCCE and, perhaps, oral/pharyngeal cancer, which were most pronounced among heavy current smokers and heavy consumers of alcohol.
Matti Narkia

Towards an adequate intake of vitamin D. An advisory report of the Health Council of th... - 0 views

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    Towards an adequate intake of vitamin D. An advisory report of the Health Council of the Netherlands
    R M Weggemans, G Schaafsma and D Kromhout
    Eur J Clin Nutr advance online publication, July 22, 2009; doi:10.1038/ejcn.2009.67
roger smith

Study suggests protein intake linked to heart attack and stroke in normal people. - 0 views

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    Increased protein intake linked to heart attack and stroke in normal people
Matti Narkia

Coffee Intake, Smoking, and Pulmonary Function in the Atherosclerosis Risk in Communiti... - 0 views

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    Coffee intake, smoking, and pulmonary function in the Atherosclerosis Risk in Communities Study.
    Nettleton JA, Follis JL, Schabath MB.
    Am J Epidemiol. 2009 Jun 15;169(12):1445-53. Epub 2009 Apr 16.
    PMID: 19372215
    doi:10.1093/aje/kwp068
Matti Narkia

Nut consumption and risk of hypertension in US male physicians - Clin Nutr. 2009 Feb - 0 views

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    Nut consumption and risk of hypertension in US male physicians.
    Djoussé L, Rudich T, Gaziano JM.
    Clin Nutr. 2009 Feb;28(1):10-4. Epub 2008 Oct 2.
    PMID: 18834651
    doi:10.1016/j.clnu.2008.08.005

    CONCLUSION: Our data suggest that nut consumption is associated with a lower risk of hypertension in US male physicians and that such relation may be influenced by adiposity.
Matti Narkia

A comparison of egg consumption with other modifiable coronary heart disease lifestyle ... - 0 views

  •  
    A comparison of egg consumption with other modifiable coronary heart disease lifestyle risk factors: a relative risk apportionment study.
    Barraj L, Tran N, Mink P.
    Risk Anal. 2009 Mar;29(3):401-15. Epub 2008 Nov 4.
    PMID: 19000074
    DOI: 10.1111/j.1539-6924.2008.01149.x

    Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for <1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.
Matti Narkia

Egg consumption and risk of type 2 diabetes in men and women. - Diabetes Care. 2009 Feb - 0 views

  •  
    Egg consumption and risk of type 2 diabetes in men and women.
    Djoussé L, Gaziano JM, Buring JE, Lee IM.
    Diabetes Care. 2009 Feb;32(2):295-300. Epub 2008 Nov 18.
    PMID: 19017774
    DOI: 10.2337/dc08-1271

    CONCLUSIONS-These data suggest that high levels of egg consumption (daily) are associated with an increased risk of type 2 diabetes in men and women. Confirmation of these findings in other populations is warranted.
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