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Bhrigu's actions are surprising, but probably not unique. There are few firm numbers showing the prevalence of research sabotage, but conversations with graduate students, postdocs and research-misconduct experts suggest that such misdeeds occur elsewhere, and that most go unreported or unpoliced. In this case, the episode set back research, wasted potentially tens of thousands of dollars and terrorized a young student. More broadly, acts such as Bhrigu's — along with more subtle actions to hold back or derail colleagues' work — have a toxic effect on science and scientists. They are an affront to the implicit trust between scientists that is necessary for research endeavours to exist and thrive.

Despite all this, there is little to prevent perpetrators re-entering science.

federal bodies that provide research funding have limited ability and inclination to take action in sabotage cases because they aren't interpreted as fitting the federal definition of research misconduct, which is limited to plagiarism, fabrication and falsification of research data.

In Bhrigu's case, administrators at the University of Michigan worked with police to investigate, thanks in part to the persistence of Ames and her supervisor, Theo Ross. "The question is, how many universities have such procedures in place that scientists can go and get that kind of support?" says Christine Boesz, former inspector-general for the US National Science Foundation in Arlington, Virginia, and now a consultant on scientific accountability. "Most universities I was familiar with would not necessarily be so responsive."

Some labs are known to be hyper-competitive, with principal investigators pitting postdocs against each other. But Ross's lab is a small, collegial place. At the time that Ames was noticing problems, it housed just one other graduate student, a few undergraduates doing projects, and the lab manager, Katherine Oravecz-Wilson, a nine-year veteran of the lab whom Ross calls her "eyes and ears". And then there was Bhrigu, an amiable postdoc who had joined the lab in April 2009.

Some people whom Ross consulted with tried to convince her that Ames was hitting a rough patch in her work and looking for someone else to blame. But Ames was persistent, so Ross took the matter to the university's office of regulatory affairs, which advises on a wide variety of rules and regulations pertaining to research and clinical care. Ray Hutchinson, associate dean of the office, and Patricia Ward, its director, had never dealt with anything like it before. After several meetings and two more instances of alcohol in the media, Ward contacted the department of public safety — the university's police force — on 9 March. They immediately launched an investigation — into Ames herself. She endured two interrogations and a lie-detector test before investigators decided to look elsewhere.

At 4:00 a.m. on Sunday 18 April, officers installed two cameras in the lab: one in the cold room where Ames's blots had been contaminated, and one above the refrigerator where she stored her media. Ames came in that day and worked until 5:00 p.m. On Monday morning at around 10:15, she found that her medium had been spiked again. When Ross reviewed the tapes of the intervening hours with Richard Zavala, the officer assigned to the case, she says that her heart sank. Bhrigu entered the lab at 9:00 a.m. on Monday and pulled out the culture media that he would use for the day. He then returned to the fridge with a spray bottle of ethanol, usually used to sterilize lab benches. With his back to the camera, he rummaged through the fridge for 46 seconds. Ross couldn't be sure what he was doing, but it didn't look good. Zavala escorted Bhrigu to the campus police department for questioning. When he told Bhrigu about the cameras in the lab, the postdoc asked for a drink of water and then confessed. He said that he had been sabotaging Ames's work since February. (He denies involvement in the December and January incidents.)

Some say that the structure of the scientific enterprise is to blame. The big rewards — tenured positions, grants, papers in stellar journals — are won through competition. To get ahead, researchers need only be better than those they are competing with. That ethos, says Brian Martinson, a sociologist at HealthPartners Research Foundation in Minneapolis, Minnesota, can lead to sabotage. He and others have suggested that universities and funders need to acknowledge the pressures in the research system and try to ease them by means of education and rehabilitation, rather than simply punishing perpetrators after the fact.

Bhrigu says that he felt pressure in moving from the small college at Toledo to the much bigger one in Michigan. He says that some criticisms he received from Ross about his incomplete training and his work habits frustrated him, but he doesn't blame his actions on that. "In any kind of workplace there is bound to be some pressure," he says. "I just got jealous of others moving ahead and I wanted to slow them down."

At Washtenaw County Courthouse in July, having reviewed the case files, Pollard Hines delivered Bhrigu's sentence. She ordered him to pay around US$8,800 for reagents and experimental materials, plus $600 in court fees and fines — and to serve six months' probation, perform 40 hours of community service and undergo a psychiatric evaluation.

But the threat of a worse sentence hung over Bhrigu's head. At the request of the prosecutor, Ross had prepared a more detailed list of damages, including Bhrigu's entire salary, half of Ames's, six months' salary for a technician to help Ames get back up to speed, and a quarter of the lab's reagents. The court arrived at a possible figure of $72,000, with the final amount to be decided upon at a restitution hearing in September.

Ross, though, is happy that the ordeal is largely over. For the month-and-a-half of the investigation, she became reluctant to take on new students or to hire personnel. She says she considered packing up her research programme. She even questioned her own sanity, worrying that she was the one sabotaging Ames's work via "an alternate personality". Ross now wonders if she was too trusting, and urges other lab heads to "realize that the whole spectrum of humanity is in your lab. So, when someone complains to you, take it seriously."

She also urges others to speak up when wrongdoing is discovered. After Bhrigu pleaded guilty in June, Ross called Trempe at the University of Toledo. He was shocked, of course, and for more than one reason. His department at Toledo had actually re-hired Bhrigu. Bhrigu says that he lied about the reason he left Michigan, blaming it on disagreements with Ross. Toledo let Bhrigu go in July, not long after Ross's call.

Now that Bhrigu is in India, there is little to prevent him from getting back into science. And even if he were in the United States, there wouldn't be much to stop him. The National Institutes of Health in Bethesda, Maryland, through its Office of Research Integrity, will sometimes bar an individual from receiving federal research funds for a time if they are found guilty of misconduct. But Bhigru probably won't face that prospect because his actions don't fit the federal definition of misconduct, a situation Ross finds strange. "All scientists will tell you that it's scientific misconduct because it's tampering with data," she says.

Ames says that the experience shook her trust in her chosen profession. "I did have doubts about continuing with science. It hurt my idea of science as a community that works together, builds upon each other's work and collaborates."