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Somewhere down the line, achieving an impact in the media seems to have become the goal in itself, rather than what it should be: a way to inform and engage the public with clarity and objectivity, without bias or prejudice. Our obsession with impact is not one-sided. The craving of scientists for publicity is fuelled by a hurried and unquestioning media, an academic community that disproportionately rewards publication in "high impact" journals such as Nature, and by research councils that emphasise the importance of achieving "impact" while at the same time delivering funding cuts. Academics are now pushed to attend media training courses, instructed about "pathways to impact", required to include detailed "impact summaries" when applying for grant funding, and constantly reminded about the importance of media engagement to further their careers. Yet where in all of this strategising and careerism is it made clear why public engagement is important? Where is it emphasised that the most crucial consideration in our interactions with the media is that we are accurate, honest and open about the limitations of our research?

Delayed gratification illustrates the interaction between the two modes. The brain is attracted by immediate rewards, no matter what kind. However, when larger rewards are eventually going to become available, other parts of the brain come into play to override (sometimes) the immediate urge.

Greene's research shows that our automatic setting is "Kantian," meaning that our intuitive responses are deontological, rule driven. The manual setting, on the other hand, tends to be more utilitarian / consequentialist. Accordingly, the first mode involves emotional areas of the brain, the second one involves more cognitive areas.

The evidence comes from the (in)famous trolley dilemma and it's many variations.

when people refuse to intervene in the footbridge (as opposed to the lever) version of the dilemma, they do so because of a strong emotional response, which contradicts the otherwise utilitarian calculus they make when considering the lever version.

psychopaths turn out to be more utilitarian than normal subjects - presumably not because consequentialism is inherently pathological, but because their emotional responses are stunted. Mood also affects the results, with people exposed to comedy (to enhance mood), for instance, more likely to say that it is okay to push the guy off the footbridge.

In a more recent experiment, subjects were asked to say which action carried the better consequences, which made them feel worse, and which was overall morally acceptable. The idea was to separate the cognitive, emotional and integrative aspects of moral decision making. Predictably, activity in the amygdala correlated with deontological judgment, activity in more cognitive areas was associated with utilitarianism, and different brain regions became involved in integrating the two.

Another recent experiment used visual vs. verbal descriptions of moral dilemmas. Turns out that more visual people tend to behave emotionally / deontologically, while more verbal people are more utilitarian.

studies show that interfering with moral judgment by engaging subjects with a cognitive task slows down (though it does not reverse) utilitarian judgment, but has no effect on deontological judgment. Again, in agreement with the conclusion that the first type of modality is the result of cognition, the latter of emotion.

Nice to know, by the way, that when experimenters controlled for "real world expectations" that people have about trolleys, or when they used more realistic scenarios than trolleys and bridges, the results don't vary. In other words, trolley thought experiments are actually informative, contrary to popular criticisms.

What factors affect people's decision making in moral judgment? The main one is proximity, with people feeling much stronger obligations if they are present to the event posing the dilemma, or even relatively near (a disaster happens in a nearby country), as opposed to when they are far (a country on the other side of the world).

Greene's general conclusion is that neuroscience matters to ethics because it reveals the hidden mechanisms of human moral decision making. However, he says this is interesting to philosophers because it may lead to question ethical theories that are implicitly or explicitly based on such judgments. But neither philosophical deontology nor consequentialism are in fact based on common moral judgments, seems to me. They are the result of explicit analysis. (Though Greene raises the possibility that some philosophers engage in rationalizing, rather than reason, as in Kant's famously convoluted idea that masturbation is wrong because one is using oneself as a mean to an end...)

this is not to say that understanding moral decision making in humans isn't interesting or in fact even helpful in real life cases. An example of the latter is the common moral condemnation of incest, which is an emotional reaction that probably evolved to avoid genetically diseased offspring. It follows that science can tell us that three is nothing morally wrong in cases of incest when precautions have been taken to avoid pregnancy (and assuming psychological reactions are also accounted for). Greene puts this in terms of science helping us to transform difficult ought questions into easier ought questions.

Carr's article touched a nerve and has provoked a lively, ongoing debate on the net and in print (he has now expanded it into a book, The Shallows: What the Internet Is Doing to Our Brains). This is partly because he's an engaging writer who has vividly articulated the unease that many adults feel about the way their modi operandi have changed in response to ubiquitous networking.

Who bothers to write down or memorise detailed information any more, for example, when they know that Google will always retrieve it if it's needed again? The web has become, in a way, a global prosthesis for our collective memory.

easy to dismiss Carr's concern as just the latest episode of the moral panic that always accompanies the arrival of a new communications technology. People fretted about printing, photography, the telephone and television in analogous ways. It even bothered Plato, who argued that the technology of writing would destroy the art of remembering.

many commentators who accept the thrust of his argument seem not only untroubled by its far-reaching implications but are positively enthusiastic about them. When the Pew Research Centre's Internet & American Life project asked its panel of more than 370 internet experts for their reaction, 81% of them agreed with the proposition that "people's use of the internet has enhanced human intelligence".

As a writer, thinker, researcher and teacher, what I can attest to is that the internet is changing our habits of thinking, which isn't the same thing as changing our brains. The brain is like any other muscle – if you don't stretch it, it gets both stiff and flabby. But if you exercise it regularly, and cross-train, your brain will be flexible, quick, strong and versatile.

he internet is analogous to a weight-training machine for the brain, as compared with the free weights provided by libraries and books. Each method has its advantage, but used properly one works you harder. Weight machines are directive and enabling: they encourage you to think you've worked hard without necessarily challenging yourself. The internet can be the same: it often tells us what we think we know, spreading misinformation and nonsense while it's at it. It can substitute surface for depth, imitation for originality, and its passion for recycling would surpass the most committed environmentalist.

I've seen students' thinking habits change dramatically: if information is not immediately available via a Google search, students are often stymied. But of course what a Google search provides is not the best, wisest or most accurate answer, but the most popular one.

But knowledge is not the same thing as information, and there is no question to my mind that the access to raw information provided by the internet is unparalleled and democratising. Admittance to elite private university libraries and archives is no longer required, as they increasingly digitise their archives. We've all read the jeremiads that the internet sounds the death knell of reading, but people read online constantly – we just call it surfing now. What they are reading is changing, often for the worse; but it is also true that the internet increasingly provides a treasure trove of rare books, documents and images, and as long as we have free access to it, then the internet can certainly be a force for education and wisdom, and not just for lies, damned lies, and false statistics.

In the end, the medium is not the message, and the internet is just a medium, a repository and an archive. Its greatest virtue is also its greatest weakness: it is unselective. This means that it is undiscriminating, in both senses of the word. It is indiscriminate in its principles of inclusion: anything at all can get into it. But it also – at least so far – doesn't discriminate against anyone with access to it. This is changing rapidly, of course, as corporations and governments seek to exert control over it. Knowledge may not be the same thing as power, but it is unquestionably a means to power. The question is, will we use the internet's power for good, or for evil? The jury is very much out. The internet itself is disinterested: but what we use it for is not.

For a complex and somewhat mysterious set of reasons, it is becoming increasingly difficult for experimental drugs to prove their superiority to sugar pills in RCTs

in recent years, however, has it become obvious that the abatement of symptoms in control-group volunteers — the so-called placebo effect — is worthy of study outside the context of drug trials, and is in fact profoundly good news to anyone but investors in Pfizer, Roche, and GlaxoSmithKline.

The emerging field of placebo research has revealed that the body’s repertoire of resilience contains a powerful self-healing network that can help reduce pain and inflammation, lower the production of stress chemicals like cortisol, and even tame high blood pressure and the tremors of Parkinson’s disease.

more and more studies each year — by researchers like Fabrizio Benedetti at the University of Turin, author of a superb new book called The Patient’s Brain, and neuroscientist Tor Wager at the University of Colorado — demonstrate that the placebo effect might be potentially useful in treating a wide range of ills. Then why aren’t doctors supposed to use it?

The medical establishment’s ethical problem with placebo treatment boils down to the notion that for fake drugs to be effective, doctors must lie to their patients. It has been widely assumed that if a patient discovers that he or she is taking a placebo, the mind/body password will no longer unlock the network, and the magic pills will cease to do their job.

For “Placebos Without Deception,” the researchers tracked the health of 80 volunteers with irritable bowel syndrome for three weeks as half of them took placebos and the other half didn’t.

In a previous study published in the British Medical Journal in 2008, Kaptchuk and Kirsch demonstrated that placebo treatment can be highly effective for alleviating the symptoms of IBS. This time, however, instead of the trial being “blinded,” it was “open.” That is, the volunteers in the placebo group knew that they were getting only inert pills — which they were instructed to take religiously, twice a day. They were also informed that, just as Ivan Pavlov trained his dogs to drool at the sound of a bell, the body could be trained to activate its own built-in healing network by the act of swallowing a pill.

In other words, in addition to the bogus medication, the volunteers were given a true story — the story of the placebo effect. They also received the care and attention of clinicians, which have been found in many other studies to be crucial for eliciting placebo effects. The combination of the story and a supportive clinical environment were enough to prevail over the knowledge that there was really nothing in the pills. People in the placebo arm of the trial got better — clinically, measurably, significantly better — on standard scales of symptom severity and overall quality of life. In fact, the volunteers in the placebo group experienced improvement comparable to patients taking a drug called alosetron, the standard of care for IBS. Meet the ethical placebo: a powerfully effective faux medication that meets all the standards of informed consent.

The study is hardly the last word on the subject, but more like one of the first. Its modest sample size and brief duration leave plenty of room for followup research. (What if “ethical” placebos wear off more quickly than deceptive ones? Does the fact that most of the volunteers in this study were women have any bearing on the outcome? Were any of the volunteers skeptical that the placebo effect is real, and did that affect their response to treatment?) Before some eager editor out there composes a tweet-baiting headline suggesting that placebos are about to drive Big Pharma out of business, he or she should appreciate the fact that the advent of AMA-approved placebo treatments would open numerous cans of fascinatingly tangled worms. For example, since the precise nature of placebo effects is shaped largely by patients’ expectations, would the advertised potency and side effects of theoretical products like Placebex and Therastim be subject to change by Internet rumors, requiring perpetual updating?

It’s common to use the word “placebo” as a synonym for “scam.” Economists talk about placebo solutions to our economic catastrophe (tax cuts for the rich, anyone?). Online skeptics mock the billion-dollar herbal-medicine industry by calling it Big Placebo. The fact that our brains and bodies respond vigorously to placebos given in warm and supportive clinical environments, however, turns out to be very real.

We’re also discovering that the power of narrative is embedded deeply in our physiology.

in the real world of doctoring, many physicians prescribe medications at dosages too low to have an effect on their own, hoping to tap into the body’s own healing resources — though this is mostly acknowledged only in whispers, as a kind of trade secret.

Wallace, in his essay, at the very center of trying to show that we can indeed make meaningful choices, places a terrorist in the middle of Amherst's campus with his finger on the trigger mechanism of a nuclear weapon. It is by far the most narratively arresting moment in all of this material, and it says far more about the author's approaching antiestablishment explosions of prose and his extreme emotional makeup than it does about tweedy profs fantasizing about ordering their ships into battle. For, after all, who, besides everyone around him, would the terrorist have killed?

But other researchers, both with and without Templeton grants, say that they find the foundation remarkably open and non-dogmatic. "The Templeton Foundation has never in my experience pressured, suggested or hinted at any kind of ideological slant," says Michael Shermer, editor of Skeptic, a magazine that debunks pseudoscience, who was hired by the foundation to edit an essay series entitled 'Does science make belief in God obsolete?'

The debate highlights some of the challenges facing the Templeton Foundation after the death of its founder in July 2008, at the age of 95.

With the help of a $528-million bequest from Templeton, the foundation has been radically reframing its research programme. As part of that effort, it is reducing its emphasis on religion to make its programmes more palatable to the broader scientific community. Like many of his generation, Templeton was a great believer in progress, learning, initiative and the power of human imagination — not to mention the free-enterprise system that allowed him, a middle-class boy from Winchester, Tennessee, to earn billions of dollars on Wall Street. The foundation accordingly allocates 40% of its annual grants to programmes with names such as 'character development', 'freedom and free enterprise' and 'exceptional cognitive talent and genius'.

Unlike most of his peers, however, Templeton thought that the principles of progress should also apply to religion. He described himself as "an enthusiastic Christian" — but was also open to learning from Hinduism, Islam and other religious traditions. Why, he wondered, couldn't religious ideas be open to the type of constructive competition that had produced so many advances in science and the free market?

That question sparked Templeton's mission to make religion "just as progressive as medicine or astronomy".

Early Templeton prizes had nothing to do with science: the first went to the Catholic missionary Mother Theresa of Calcutta in 1973.

By the 1980s, however, Templeton had begun to realize that fields such as neuroscience, psychology and physics could advance understanding of topics that are usually considered spiritual matters — among them forgiveness, morality and even the nature of reality. So he started to appoint scientists to the prize panel, and in 1985 the award went to a research scientist for the first time: Alister Hardy, a marine biologist who also investigated religious experience. Since then, scientists have won with increasing frequency.

"There's a distinct feeling in the research community that Templeton just gives the award to the most senior scientist they can find who's willing to say something nice about religion," says Harold Kroto, a chemist at Florida State University in Tallahassee, who was co-recipient of the 1996 Nobel Prize in Chemistry and describes himself as a devout atheist.

Yet Templeton saw scientists as allies. They had what he called "the humble approach" to knowledge, as opposed to the dogmatic approach. "Almost every scientist will agree that they know so little and they need to learn," he once said.

Templeton wasn't interested in funding mainstream research, says Barnaby Marsh, the foundation's executive vice-president. Templeton wanted to explore areas — such as kindness and hatred — that were not well known and did not attract major funding agencies. Marsh says Templeton wondered, "Why is it that some conflicts go on for centuries, yet some groups are able to move on?"

Templeton's interests gave the resulting list of grants a certain New Age quality (See Table 1). For example, in 1999 the foundation gave $4.6 million for forgiveness research at the Virginia Commonwealth University in Richmond, and in 2001 it donated $8.2 million to create an Institute for Research on Unlimited Love (that is, altruism and compassion) at Case Western Reserve University in Cleveland, Ohio. "A lot of money wasted on nonsensical ideas," says Kroto. Worse, says Coyne, these projects are profoundly corrupting to science, because the money tempts researchers into wasting time and effort on topics that aren't worth it. If someone is willing to sell out for a million dollars, he says, "Templeton is there to oblige him".

At the same time, says Marsh, the 'dean of value investing', as Templeton was known on Wall Street, had no intention of wasting his money on junk science or unanswerables such as whether God exists. So before pursuing a scientific topic he would ask his staff to get an assessment from appropriate scholars — a practice that soon evolved into a peer-review process drawing on experts from across the scientific community.

Because Templeton didn't like bureaucracy, adds Marsh, the foundation outsourced much of its peer review and grant giving. In 1996, for example, it gave $5.3 million to the American Association for the Advancement of Science (AAAS) in Washington DC, to fund efforts that work with evangelical groups to find common ground on issues such as the environment, and to get more science into seminary curricula. In 2006, Templeton gave $8.8 million towards the creation of the Foundational Questions Institute (FQXi), which funds research on the origins of the Universe and other fundamental issues in physics, under the leadership of Anthony Aguirre, an astrophysicist at the University of California, Santa Cruz, and Max Tegmark, a cosmologist at the Massachusetts Institute of Technology in Cambridge.

But external peer review hasn't always kept the foundation out of trouble. In the 1990s, for example, Templeton-funded organizations gave book-writing grants to Guillermo Gonzalez, an astrophysicist now at Grove City College in Pennsylvania, and William Dembski, a philosopher now at the Southwestern Baptist Theological Seminary in Fort Worth, Texas. After obtaining the grants, both later joined the Discovery Institute — a think-tank based in Seattle, Washington, that promotes intelligent design. Other Templeton grants supported a number of college courses in which intelligent design was discussed. Then, in 1999, the foundation funded a conference at Concordia University in Mequon, Wisconsin, in which intelligent-design proponents confronted critics. Those awards became a major embarrassment in late 2005, during a highly publicized court fight over the teaching of intelligent design in schools in Dover, Pennsylvania. A number of media accounts of the intelligent design movement described the Templeton Foundation as a major supporter — a charge that Charles Harper, then senior vice-president, was at pains to deny.

Some foundation officials were initially intrigued by intelligent design, Harper told The New York Times. But disillusionment set in — and Templeton funding stopped — when it became clear that the theory was part of a political movement from the Christian right wing, not science. Today, the foundation website explicitly warns intelligent-design researchers not to bother submitting proposals: they will not be considered.

Avowedly antireligious scientists such as Coyne and Kroto see the intelligent-design imbroglio as a symptom of their fundamental complaint that religion and science should not mix at all. "Religion is based on dogma and belief, whereas science is based on doubt and questioning," says Coyne, echoing an argument made by many others. "In religion, faith is a virtue. In science, faith is a vice." The purpose of the Templeton Foundation is to break down that wall, he says — to reconcile the irreconcilable and give religion scholarly legitimacy.

Foundation officials insist that this is backwards: questioning is their reason for being. Religious dogma is what they are fighting. That does seem to be the experience of many scientists who have taken Templeton money. During the launch of FQXi, says Aguirre, "Max and I were very suspicious at first. So we said, 'We'll try this out, and the minute something smells, we'll cut and run.' It never happened. The grants we've given have not been connected with religion in any way, and they seem perfectly happy about that."

John Cacioppo, a psychologist at the University of Chicago, also had concerns when he started a Templeton-funded project in 2007. He had just published a paper with survey data showing that religious affiliation had a negative correlation with health among African-Americans — the opposite of what he assumed the foundation wanted to hear. He was bracing for a protest when someone told him to look at the foundation's website. They had displayed his finding on the front page. "That made me relax a bit," says Cacioppo.

Yet, even scientists who give the foundation high marks for openness often find it hard to shake their unease. Sean Carroll, a physicist at the California Institute of Technology in Pasadena, is willing to participate in Templeton-funded events — but worries about the foundation's emphasis on research into 'spiritual' matters. "The act of doing science means that you accept a purely material explanation of the Universe, that no spiritual dimension is required," he says.

It hasn't helped that Jack Templeton is much more politically and religiously conservative than his father was. The foundation shows no obvious rightwards trend in its grant-giving and other activities since John Templeton's death — and it is barred from supporting political activities by its legal status as a not-for-profit corporation. Still, many scientists find it hard to trust an organization whose president has used his personal fortune to support right-leaning candidates and causes such as the 2008 ballot initiative that outlawed gay marriage in California.

Scientists' discomfort with the foundation is probably inevitable in the current political climate, says Scott Atran, an anthropologist at the University of Michigan in Ann Arbor. The past 30 years have seen the growing power of the Christian religious right in the United States, the rise of radical Islam around the world, and religiously motivated terrorist attacks such as those in the United States on 11 September 2001. Given all that, says Atran, many scientists find it almost impossible to think of religion as anything but fundamentalism at war with reason.

the foundation has embraced the theme of 'science and the big questions' — an open-ended list that includes topics such as 'Does the Universe have a purpose?'

Towards the end of Templeton's life, says Marsh, he became increasingly concerned that this reaction was getting in the way of the foundation's mission: that the word 'religion' was alienating too many good scientists.

The peer-review and grant-making system has also been revamped: whereas in the past the foundation ran an informal mix of projects generated by Templeton and outside grant seekers, the system is now organized around an annual list of explicit funding priorities.

The foundation is still a work in progress, says Jack Templeton — and it always will be. "My father believed," he says, "we were all called to be part of an ongoing creative process. He was always trying to make people think differently." "And he always said, 'If you're still doing today what you tried to do two years ago, then you're not making progress.'" 

So, does this mean that we should throw away all those pen-and-paper and survey-based studies of religion. Well no - they still tell us something. It's just not entirely clear what they are telling us!

The theory of motivated reasoning builds on a key insight of modern neuroscience (PDF): Reasoning is actually suffused with emotion (or what researchers often call "affect"). Not only are the two inseparable, but our positive or negative feelings about people, things, and ideas arise much more rapidly than our conscious thoughts, in a matter of milliseconds—fast enough to detect with an EEG device, but long before we're aware of it. That shouldn't be surprising: Evolution required us to react very quickly to stimuli in our environment. It's a "basic human survival skill," explains political scientist Arthur Lupia of the University of Michigan. We push threatening information away; we pull friendly information close. We apply fight-or-flight reflexes not only to predators, but to data itself.

We're not driven only by emotions, of course—we also reason, deliberate. But reasoning comes later, works slower—and even then, it doesn't take place in an emotional vacuum. Rather, our quick-fire emotions can set us on a course of thinking that's highly biased, especially on topics we care a great deal about.

Consider a person who has heard about a scientific discovery that deeply challenges her belief in divine creation—a new hominid, say, that confirms our evolutionary origins. What happens next, explains political scientist Charles Taber of Stony Brook University, is a subconscious negative response to the new information—and that response, in turn, guides the type of memories and associations formed in the conscious mind. "They retrieve thoughts that are consistent with their previous beliefs," says Taber, "and that will lead them to build an argument and challenge what they're hearing."

when we think we're reasoning, we may instead be rationalizing. Or to use an analogy offered by University of Virginia psychologist Jonathan Haidt: We may think we're being scientists, but we're actually being lawyers (PDF). Our "reasoning" is a means to a predetermined end—winning our "case"—and is shot through with biases. They include "confirmation bias," in which we give greater heed to evidence and arguments that bolster our beliefs, and "disconfirmation bias," in which we expend disproportionate energy trying to debunk or refute views and arguments that we find uncongenial.