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kenneth yang

SD ballot measure would ease restrictions on stem cell research - 1 views

PIERRE, S.D. (AP) - A proposed ballot issue to ease restrictions on stem cell research will strike a chord with South Dakotans because nearly everyone has had a serious disease or knows someone who...

ethics rights stem cell

started by kenneth yang on 21 Oct 09 no follow-up yet
Weiye Loh

m.guardian.co.uk - 0 views

  • perhaps the reason stem cells managed to lodge themselves so deep in the public psyche was not just because of their awesome scientific potential, or their ability to turn into the treatments of the future.
  • For years, stem cells dominated all other science stories in newspaper headlines because they framed an ethical conundrum – to get to the most versatile stem cells meant destroying human embryos.
  • Research on stem cells became a political football, leading to delays in funding for scientists, particularly in the US. Not that the work itself was straightforward – the process of extracting stem cells from embryos is difficult and there is a very limited supply of material. Inevitable disappointment followed the years of headlines – where were the promised treatments? Was it all over-hyped?
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  • Key to this is the discovery, in the past few years, of a way to make stem cells that do not require the destruction of embryos. In one move, these induced pluripotent stem (iPS) cells remove the ethical roadblocks faced by embryonic stem cells and, because they are so much easier to make, give scientists an inexhaustible supply of material, bringing them ever closer to those hoped-for treatments.
  • Stem cells are the body's master cells, the raw material from which we are built. Unlike normal body cells, they can reproduce an indefinite number of times and, when prodded in the right way, can turn themselves into any type of cell in the body. The most versatile stem cells are those found in the embryo at just a few days old – this ball of a few dozen embryonic stem (ES) cells eventually goes on to form everything that makes up a person.
Weiye Loh

"Stem Cell City" To Make All Research Available To The Public | The Utopianist - Think ... - 0 views

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    A new website launched in Toronto allows the public to peruse all the current research on stem cells, as well as take a tour of a lab and stay updated on any specific disease - all in the hopes of educating us about a line of research that has huge potential to save a lot of lives. The ethical and political controversy hovering over work with stem cells, particularly embryonic cells - which have the biggest potential but pose the greatest ethical problems - has made work in the field particularly jittery; stop and go funding, as well as confusion about the concept in the public sector hasn't made for the most ideal working conditions. Stem Cell City - an online portal launched yesterday may significantly contribute to the cause, its founding scientists hope.
Satveer

Why I hate stem-cell technologies & Regenerative Therapies - 5 views

http://news.bbc.co.uk/2/hi/health/8314442.stm This article is another one of those regenerative therapies article that use of stem-cell technology to reverse aging because first world countries ar...

stem cell regenerative first world third

started by Satveer on 21 Oct 09 no follow-up yet
Weiye Loh

Science scorned : Nature : Nature Publishing Group - 0 views

  • There is a growing anti-science streak on the American right that could have tangible societal and political impacts on many fronts — including regulation of environmental and other issues and stem-cell research.
  • The right-wing populism that is flourishing in the current climate of economic insecurity echoes many traditional conservative themes, such as opposition to taxes, regulation and immigration. But the Tea Party and its cheerleaders, who include Limbaugh, Fox News television host Glenn Beck and Sarah Palin (who famously decried fruitfly research as a waste of public money), are also tapping an age-old US political impulse — a suspicion of elites and expertise.
  • Denialism over global warming has become a scientific cause célèbre within the movement. Limbaugh, for instance, who has told his listeners that “science has become a home for displaced socialists and communists”, has called climate-change science “the biggest scam in the history of the world”. The Tea Party's leanings encompass religious opposition to Darwinian evolution and to stem-cell and embryo research — which Beck has equated with eugenics. The movement is also averse to science-based regulation, which it sees as an excuse for intrusive government. Under the administration of George W. Bush, science in policy had already taken knocks from both neglect and ideology. Yet President Barack Obama's promise to “restore science to its rightful place” seems to have linked science to liberal politics, making it even more of a target of the right.
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  • US citizens face economic problems that are all too real, and the country's future crucially depends on education, science and technology as it faces increasing competition from China and other emerging science powers.
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    Science Scorned  The anti-science strain pervading the right wing in the United States is the last thing the country needs in a time of economic challenge.
Weiye Loh

Skepticblog » Investing in Basic Science - 0 views

  • A recent editorial in the New York Times by Nicholas Wade raises some interesting points about the nature of basic science research – primarily that its’ risky.
  • As I have pointed out about the medical literature, researcher John Ioaniddis has explained why most published studies turn out in retrospect to be wrong. The same is true of most basic science research – and the underlying reason is the same. The world is complex, and most of our guesses about how it might work turn out to be either flat-out wrong, incomplete, or superficial. And so most of our probing and prodding of the natural world, looking for the path to the actual answer, turn out to miss the target.
  • research costs considerable resources of time, space, money, opportunity, and people-hours. There may also be some risk involved (such as to subjects in the clinical trial). Further, negative studies are actually valuable (more so than terrible pictures). They still teach us something about the world – they teach us what is not true. At the very least this narrows the field of possibilities. But the analogy holds in so far as the goal of scientific research is to improve our understanding of the world and to provide practical applications that make our lives better. Wade writes mostly about how we fund research, and this relates to our objectives. Most of the corporate research money is interested in the latter – practical (and profitable) applications. If this is your goal, than basic science research is a bad bet. Most investments will be losers, and for most companies this will not be offset by the big payoffs of the rare winners. So many companies will allow others to do the basic science (government, universities, start up companies) then raid the winners by using their resources to buy them out, and then bring them the final steps to a marketable application. There is nothing wrong or unethical about this. It’s a good business model.
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  • What, then, is the role of public (government) funding of research? Primarily, Wade argues (and I agree), to provide infrastructure for expensive research programs, such as building large colliders.
  • the more the government invests in basic science and infrastructure, the more winners will emerge that private industry can then capitalize on. This is a good way to build a competitive dynamic economy.
  • But there is a pitfall – prematurely picking winners and losers. Wade give the example of California investing specifically into developing stem cell treatments. He argues that stem cells, while promising, do not hold a guarantee of eventual success, and perhaps there are other technologies that will work and are being neglected. The history of science and technology has clearly demonstrated that it is wickedly difficult to predict the future (and all those who try are destined to be mocked by future generations with the benefit of perfect hindsight). Prematurely committing to one technology therefore contains a high risk of wasting a great deal of limited resources, and missing other perhaps more fruitful opportunities.
  • The underlying concept is that science research is a long-term game. Many avenues of research will not pan out, and those that do will take time to inspire specific applications. The media, however, likes catchy headlines. That means when they are reporting on basic science research journalists ask themselves – why should people care? What is the application of this that the average person can relate to? This seems reasonable from a journalistic point of view, but with basic science reporting it leads to wild speculation about a distant possible future application. The public is then left with the impression that we are on the verge of curing the common cold or cancer, or developing invisibility cloaks or flying cars, or replacing organs and having household robot servants. When a few years go by and we don’t have our personal android butlers, the public then thinks that the basic science was a bust, when in fact there was never a reasonable expectation that it would lead to a specific application anytime soon. But it still may be on track for interesting applications in a decade or two.
  • this also means that the government, generally, should not be in the game of picking winners an losers – putting their thumb on the scale, as it were. Rather, they will get the most bang for the research buck if they simply invest in science infrastructure, and also fund scientists in broad areas.
  • The same is true of technology – don’t pick winners and losers. The much-hyped “hydrogen economy” comes to mind. Let industry and the free market sort out what will work. If you have to invest in infrastructure before a technology is mature, then at least hedge your bets and keep funding flexible. Fund “alternative fuel” as a general category, and reassess on a regular basis how funds should be allocated. But don’t get too specific.
  • Funding research but leaving the details to scientists may be optimal
  • The scientific community can do their part by getting better at communicating with the media and the public. Try to avoid the temptation to overhype your own research, just because it is the most interesting thing in the world to you personally and you feel hype will help your funding. Don’t make it easy for the media to sensationalize your research – you should be the ones trying to hold back the reigns. Perhaps this is too much to hope for – market forces conspire too much to promote sensationalism.
Weiye Loh

How the net traps us all in our own little bubbles | Technology | The Observer - 0 views

  • Google would use 57 signals – everything from where you were logging in from to what browser you were using to what you had searched for before – to make guesses about who you were and what kinds of sites you'd like. Even if you were logged out, it would customise its results, showing you the pages it predicted you were most likely to click on.
  • Most of us assume that when we google a term, we all see the same results – the ones that the company's famous Page Rank algorithm suggests are the most authoritative based on other pages' links. But since December 2009, this is no longer true. Now you get the result that Google's algorithm suggests is best for you in particular – and someone else may see something entirely different. In other words, there is no standard Google any more.
  • In the spring of 2010, while the remains of the Deepwater Horizon oil rig were spewing oil into the Gulf of Mexico, I asked two friends to search for the term "BP". They're pretty similar – educated white left-leaning women who live in the north-east. But the results they saw were quite different. One saw investment information about BP. The other saw news.
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  • the query "stem cells" might produce diametrically opposed results for scientists who support stem-cell research and activists who oppose it.
  • "Proof of climate change" might turn up different results for an environmental activist and an oil-company executive.
  • majority of us assume search engines are unbiased. But that may be just because they're increasingly biased to share our own views. More and more, your computer monitor is a kind of one-way mirror, reflecting your own interests while algorithmic observers watch what you click. Google's announcement marked the turning point of an important but nearly invisible revolution in how we consume information. You could say that on 4 December 2009 the era of personalisation began.
  • We are predisposed to respond to a pretty narrow set of stimuli – if a piece of news is about sex, power, gossip, violence, celebrity or humour, we are likely to read it first. This is the content that most easily makes it into the filter bubble. It's easy to push "Like" and increase the visibility of a friend's post about finishing a marathon or an instructional article about how to make onion soup. It's harder to push the "Like" button on an article titled "Darfur sees bloodiest month in two years". In a personalised world, important but complex or unpleasant issues – the rising prison population, for example, or homelessness – are less likely to come to our attention at all.
  • As a consumer, it's hard to argue with blotting out the irrelevant and unlikable. But what is good for consumers is not necessarily good for citizens. What I seem to like may not be what I actually want, let alone what I need to know to be an informed member of my community or country. "It's a civic virtue to be exposed to things that appear to be outside your interest," technology journalist Clive Thompson told me. Cultural critic Lee Siegel puts it a different way: "Customers are always right, but people aren't."
  • Personalisation is based on a bargain. In exchange for the service of filtering, you hand large companies an enormous amount of data about your daily life – much of which you might not trust friends with.
  • To be the author of your life, professor Yochai Benkler argues, you have to be aware of a diverse array of options and lifestyles. When you enter a filter bubble, you're letting the companies that construct it choose which options you're aware of. You may think you're the captain of your own destiny, but personalisation can lead you down a road to a kind of informational determinism in which what you've clicked on in the past determines what you see next – a web history you're doomed to repeat. You can get stuck in a static, ever- narrowing version of yourself – an endless you-loop.
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    An invisible revolution has taken place is the way we use the net, but the increasing personalisation of information by search engines such as Google threatens to limit our access to information and enclose us in a self-reinforcing world view, writes Eli Pariser in an extract from The Filter Bubble
Weiye Loh

TODAYonline | World | Off-the-shelf body parts? - 0 views

  • LONDON - Scientific advances including techniques allowing patients to grow new joints inside their own bodies will allow the elderly to remain active well beyond their 100th birthdays, researchers claim. British scientists are working on a system which should allow the elderly to buy body parts "off the shelf" and even regenerate their own damaged joints and hearts. Their ultimate aim is to fix up the body with customised replacement parts grown to order. They have already carried out human trials on heart valves which are still working four years after they were transplanted. At the University of Leeds, Britain's biggest bioengineering unit and the world leader in artificial joint replacement research is coordinating a project that aims to give people 50 active years after the age of 50."It is the rise of the bionic pensioner," said Professor Christina Doyle, whose company is working with the university to develop the new technologies. "The idea is when something wears out, your surgeon can buy a replacement off the shelf or, more accurately, in a bag."The university is spending £50 million ($114 million) over the next five years on the new project. The main thrust of the research centres on a method of tissue and medical engineering which the university is at the forefront of developing. Led by the immunologist Professor Eileen Ingham, they are pioneering a technique of stripping the living cells from donor human and animal parts, leaving just the collagen or elastin "scaffold" of the tissue. These "biological shells", which could be for knee, ankle or hip ligaments, as well as blood vessels and heart valves, are then transplanted into the patient whose own body then invades them replacing the removed cells with their own. The technique, which could be available within five years, effectively removes the need for anti-rejection drugs. It is similar to the recently developed system of using stem cells to regrow organs outside the body, but costs about a tenth of the price.
Weiye Loh

Basics - Another Challenge for Ethical Eating - Plants Want to Live, Too - NYTimes.com - 0 views

  • Food choices are often like that: difficult to articulate yet strongly held. And lately, debates over food choices have flared with particular vehemence.
  • Gary Steiner, a philosopher at Bucknell University, argued on the Op-Ed page of The New York Times that people should strive to be “strict ethical vegans” like himself, avoiding all products derived from animals, including wool and silk. Killing animals for human food and finery is nothing less than “outright murder,”
  • we might consider that plants no more aspire to being stir-fried in a wok than a hog aspires to being peppercorn-studded in my Christmas clay pot.
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  • Plants are lively and seek to keep it that way.
  • their keen sensitivity to the environment, the speed with which they react to changes in the environment, and the extraordinary number of tricks that plants will rally to fight off attackers and solicit help from afar
  • When plant biologists speak of their subjects, they use active verbs and vivid images. Plants “forage” for resources like light and soil nutrients and “anticipate” rough spots and opportunities.
  • Plants can’t run away from a threat but they can stand their ground. “They are very good at avoiding getting eaten,”
  • At the smallest nip to its leaves, specialized cells on the plant’s surface release chemicals to irritate the predator or sticky goo to entrap it. Genes in the plant’s DNA are activated to wage systemwide chemical warfare, the plant’s version of an immune response.
  • in less than 20 minutes from the moment the caterpillar had begun feeding on its leaves, the plant had plucked carbon from the air and forged defensive compounds from scratch.
  • Just because we humans can’t hear them doesn’t mean plants don’t howl. Some of the compounds that plants generate in response to insect mastication — their feedback, you might say — are volatile chemicals that serve as cries for help. Such airborne alarm calls have been shown to attract both large predatory insects like dragon flies, which delight in caterpillar meat, and tiny parasitic insects, which can infect a caterpillar and destroy it from within.
  • certain plants can sense when insect eggs have been deposited on their leaves and will act immediately to rid themselves of the incubating menace. They may sprout carpets of tumorlike neoplasms to knock the eggs off, or secrete ovicides to kill them
  • when a female cabbage butterfly lays her eggs on a brussels sprout plant and attaches her treasures to the leaves with tiny dabs of glue, the vigilant vegetable detects the presence of a simple additive in the glue, benzyl cyanide. Cued by the additive, the plant swiftly alters the chemistry of its leaf surface to beckon female parasitic wasps. Spying the anchored bounty, the female wasps in turn inject their eggs inside, the gestating wasps feed on the gestating butterflies, and the plant’s problem is solved.
  • seedlings of the dodder plant, a parasitic weed related to morning glory, can detect volatile chemicals released by potential host plants like the tomato. The young dodder then grows inexorably toward the host, until it can encircle the victim’s stem and begin sucking the life phloem right out of it. The parasite can even distinguish between the scents of healthier and weaker tomato plants and then head for the hale one.
  • It’s a small daily tragedy that we animals must kill to stay alive. Plants are the ethical autotrophs here, the ones that wrest their meals from the sun. Don’t expect them to boast: they’re too busy fighting to survive.
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    Sorry, Vegans: Brussels Sprouts Like to Live, Too
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    Eh bro, even after results are out you're still relentless with the postings. It's the hols man...
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