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Imiquimod cream (Aldara) for superficial basal cell carcinoma: NPS - Better choices, Be... - 0 views

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    Imiquimod cream (Aldara) for superficial basal cell carcinoma
avivajazz  jazzaviva

Mohs Surgery Animation Handout - Doctor recommended review - 0 views

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    Mohs surgery technique is is typically reserved for skin cancers that have a high risk of reappearing or for skin cancers that have recurred. Mohs surgery is also a preferred option for removing skin cancer from areas such as the face
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Mohs surgery in sBCC following treatment with imiquimod 5% cream - 0 views

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    Eight of nine individuals, 89% (95% CI 56% to 97%) were histologically clear of sBCC at 52 weeks.
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Use of 5% imiquimod cream in the treatment of facial basal cell carcinoma: A 3-year re... - 0 views

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    PDF, Free full text article... We found that 5% imiquimod cream is aneffective treatment option for superficial and nodularbasal cell carcinomas, giving a clearance rate of89.5% at an average of 39 months of follow up.  
    Dr Yin Vun, Siller Medical, 9th Floor, SilvertonPlace, 101 Wickham Terrace, Brisbane, Qld 4000, Australia.
avivajazz  jazzaviva

New Skin Cancer Treatment Approved - Skin Diseases, Conditions, Symptoms, and Procedure... - 0 views

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    79% of patients had no evidence of their sBCC at two years after finishing treatment.
avivajazz  jazzaviva

Aldara (tm) [imiquimod] Cream ~ Full Prescribing Information ~ FDA / Package Insert - 0 views

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    FDA-approval: 
    * Biopsy-confirmed, primary superficial basal cell carcinoma (sBCC) in immunocompetent adults; maximum tumor diameter of 2.0 cm on trunk, neck, or extremities (excluding hands and feet), only when surgical methods are medically less appropriate and patient follow-up can be reasonably assured (1.2)
avivajazz  jazzaviva

Superficial basal cell carcinoma on face treated with 5% imiquimod cream Malhotra AK, B... - 0 views

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    The precise mechanism of the anti-tumor effect of imiquimod in BCC is not known. It has been postulated that ultraviolet radiation induces mutations in the tumor-suppressor genes and alters the immuno-surveillance, so that tumor cells escape from cytotoxic T cells and apoptosis.[1] Th-2 cytokines, that downregulate tumor surveillance, are raised in BCC.[1],[5] Imiquimod acts on toll-like receptor-7 (TLR-7) present on dendritic cells, macrophages and monocytes and induces expression of interferons, Th-1 cytokines (IL-1, IL-6, IL-10 and IL-12), tumor necrosis factor-a and G-CSF, thereby counteracting Th2 cytokines and promoting tumor surveillance.[1],[5] It also enhances the activity of natural killer cells and epidermal Langerhans' cells. The tumor regression is achieved probably by induction of Fas receptors on the tumor cells resulting in their apoptosis.[10]
avivajazz  jazzaviva

Treatment of Cutaneous Tumors with Topical 5% Imiquimod Cream | Alessi SS, et al | CLIN... - 0 views

    • avivajazz  jazzaviva
       
      For patients without comorbidities, our study revealed good cure rates for superficial BCC and superficial/nodular BCC (88% and 85%, respectively). Nodular and aggressive BCC and Bowen's disease exhibited lower cure rates (50%, 50%, and 57%, respectively). I
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    For patients without comorbidities, our study revealed good cure rates for superficial BCC and superficial/nodular BCC (88% and 85%, respectively). Nodular and aggressive BCC and Bowen's disease exhibited lower cure rates (50%, 50%, and 57%, respectively). I
avivajazz  jazzaviva

Recurrence rate of superficial basal cell carcinoma following successful treatment with... - 0 views

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    The initial sBCC clearance rate was 90% (12-week post treatment), whereas the proportion of subjects who were clinically clear at 2 years (current time point) was estimated to be 79.4%. 
avivajazz  jazzaviva

Recurrence rate of superficial basal cell carcinom... [Eur J Dermatol. 2005 Sep-Oct] - ... - 0 views

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    The initial sBCC clearance rate was 90% (12-week post treatment), whereas the proportion of subjects who were clinically clear at 2 years (current time point) was estimated to be 79.4%.
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