The Department of Health and Social Care (DHSC) has commenced a consultation on allowing pharmacists to dispense prescription medicines in original packaging.
The consultation, closing on December 13, 2021, proposes changes to the Human Medicines Regulations (HMRs).
It would allow pharmacists to dispense more or less than the 10 per cent of the prescribed quantity in original packs, except where this would affect the patient's
clinical treatment. The change would not apply to controlled drugs.
The second proposed change is to supply sodium valproate in original packaging regardless of the conditions set around Original Pack Dispensing (OPD).
Currently, contractors have to supply the exact quantity prescribed, unless certain exceptions apply.
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Pharmaceutical Services Negotiating Committee (PSNC) has expressed its support for alterations in the Human Medicines Regulations 2012 to enable original pack dispensing (OPD) and supply of medicines containing sodium valproate by pharmacists.
PSNC's support for changes was in response to the consultation on OPD, initiated by the Department of Health and Social Care (DHSC).
The consultation had proposed regulatory changes to allow pharmacists to dispense (up to 10 per cent) more or less than the prescribed quantity of a given medicine in the manufacturer's original packs.
Key aims of the proposal are to "support increased patient safety by ensuring patients receive the necessary information that is included in the original manufacturer's packaging about the safe and effective use of a product," DHSC said.
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a second "bivalent" vaccine as a Covid-19 booster.
The updated booster vaccine made by Pfizer/BioNTech, targeting two coronavirus variants, has been approved for use in individuals aged 12 years and above.
In each dose of the booster vaccine, 'Comirnaty bivalent Original/Omicron', half of the vaccine (15 micrograms) targets the original virus strain and the other
half (15 micrograms) targets Omicron (BA.1).
Dr June Raine, MHRA chief executive said: "I am pleased to announce that we now have a second approved vaccine for the UK Autumn booster programme. The clinical
trial of the Pfizer/BioNTech bivalent vaccine showed a strong immune response against the Omicron BA.1 variant as well as the original strain.
Bivalent vaccines are helping us to meet the challenge of an ever-evolving virus, to help protect people against Covid-19 variants. We have in place a comprehensive
safety surveillance strategy for all UK-approved Covid-19 vaccines, and this will include the updated booster we approved today."
Britain has become the first country to approve a Codiv-19 vaccine that targets both the original and Omicron variant of the virus.
Medicines regulator MHRA approved the so-called bivalent vaccine made by US drug company Moderna as a booster for adults.
The agency's decision was based on clinical trial data that showed the booster triggered "a strong immune response" against both Omicron (BA.1) and the original
2020 virus, it said.
The MHRA also cited an exploratory analysis in which the shot was also found to generate a good immune response against the currently dominant Omicron offshoots BA.4
and BA.5.
"The first generation of Covid-19 vaccines being used in the UK continue to provide important protection against the disease and save lives," MHRA chief executive
June Raine said in a statement.
"What this bivalent vaccine gives us is a sharpened tool in our armoury to help protect us against this disease as the virus continues to evolve."
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The regulatory amendments proposed will enable pharmacists to dispense medicines in their original packaging for private prescriptions starting this
Autumn, according to the Department of Health and Social Care.
In the recently published draft OPD regulations, the DHSC has indicated that the alterations, permitting pharmacists to vary the dispensed quantity by up to
10 per cent to avoid splitting medicine packs, will be implemented for private prescriptions 'immediately upon the enforcement of the Human Medicines Amendment
Regulations in the autumn,' as highlighted in a briefing by Community Pharmacy England.
CPE stated that the regulations related to NHS prescriptions will come into effect when the pharmaceutical terms of service regulations expressly apply the OPD
amendments.
Moreover, new directive mandating the dispensing of sodium valproate products solely in their original packaging (except when an assessment of risk necessitates
an alternative approach) will align with the rollout of the private prescription regulations during the autumn.
CPE further noted that these regulations are currently in draft, indicating that they are not currently in effect and may undergo revisions prior to their
implementation.
Britain's Covid booster campaign is set to kick off this September, after the country became the first in the world to approve an Omicron-adapted shot.
Around 26 million people in Britain are estimated to be eligible for an autumn Covid-19 booster, having had at least two Covid vaccine doses already, a UK Health
Security Agency (UKHSA) spokesperson said.
The preference is to deploy what is known as a "bivalent vaccine" that targets both the original virus and the Omicron variant through the autumn campaign, but that
will depend on the health regulator (MHRA) approving such shots and the state of vaccine supplies.
The UK's Joint Committee on Vaccination and Immunisation (JCVI) has advised boosters should be given to over-50s, individuals in clinical risk groups, frontline
workers and care-home staff ahead of the winter, when respiratory viruses are typically at their peak.
On Monday (August 15), the MHRA gave Moderna's bivalent shot conditional approval.
The endorsement of the vaccine is based on data that showed it produced a marginally better immune response against some Omicron variants, versus the original novel
coronavirus - although whether that translates into stronger protection against serious disease is unclear.
The Department of Health and Social Care (DHSC) and the Medicines and Healthcare Products Regulatory Agency (MHRA) have authorised community pharmacies
throughout the UK to dispense original full packs of Valproate-containing medicines upon prescription.
The necessary changes in regulations came into effect on 11 October which was strongly supported by 85 per cent of respondents concerned about risks to the
unborn baby if valproate-containing medicines are used in pregnancy.
The decision was made to ensure patients receive safety warnings and pictograms, including a patient card and the Patient Information Leaflet (PIL), contained
in the manufacturer's original full pack.
Valproate is a treatment for epilepsy and bipolar disorder but is also associated with birth defects and neurological disabilities.
The world's first human challenge trial in which volunteers were deliberately exposed to Covid-19 to advance research into the disease was found to be safe in
healthy young adults, one of the companies running the study said on Wednesday.
The data supports the safety of this model which could theoretically provide a "plug and play" platform for testing therapies and vaccines using the original
Covid-19 strain as well as variants of the virus, Open Orphan, which carried out the study, said in a statement.
Open Orphan is running the project, launched a year ago, with Imperial College London, the UK government's vaccines task force and the clinical company hVIVO.
The trial infected 36 healthy male and female volunteers aged 18-29 years with the original SARS-CoV-2 strain of the virus and closely monitored them in a controlled
quarantined setting. They will be followed up for 12 months after discharge from the quarantine facility.
Proper drug storage is essential to ensure the safety of yourself, your family, and those around you. This is especially important if you are taking multiple
medications and need to keep track of them all. Knowing how to store drugs correctly can help prevent misuse or accidental ingestion by children or pets. Here are
six important guidelines about proper drug storage that everyone should follow:
1. KEEP ALL MEDICATIONS IN THEIR ORIGINAL, LABELED CONTAINERS:
Using alternative storage containers can make it difficult to identify medications or keep track of expiration dates. Keeping medications in their original containers
also prevents accidental misuse and helps ensure that the correct dosage is taken. In addition, it's important to store all medications out of reach of children and
pets. Also, keep medications in a cool, dry place away from direct sunlight. For example, a medicine cabinet in the bathroom or kitchen is a good option.
2. DISPOSE OF EXPIRED MEDICATIONS:
Expired medications can be less effective and even potentially harmful if taken, so it's important to regularly check expiration dates and get rid of any outdated
medications. The best way to dispose of old drugs is to take them to a drug collection site. If no such sites are available, mix the medication with something like
coffee grounds, put it in an opaque container, and then throw it away in your trash bin. Never flush expired medication down the toilet unless instructed by your
pharmacist or healthcare provider!
3. STORE DRUGS IN A COOL, DRY PLACE:
Extreme temperatures can cause medications to break down and become ineffective. To avoid this, keep all drugs away from direct sunlight, heat sources, and moisture.
A medicine cabinet or drawer in the bathroom is an ideal spot for storing most drugs, but some require special storage conditions (more on that below). Different
medications should also be separated from one another to avoid confusion and stored differently. For example, if a
Paydens Pharmacy Group, one of the first multiple pharmacies to adopt hub and spoke model last year, revealed that the move has resulted in significant time
savings in store.
Centralising dispensing of repeat prescriptions relieves pressure in pharmacy branches and releases time to deliver revenue generating services, the group said.
The group created a hub in Maidstone, Kent, to service its highest dispensing branches. The hub uses Centred Solution's FLOWRx Hub Auto to dispense their original
pack repeat prescriptions. The group put in the first FLOWRx Hub production line in spring 2022 and then added in a second line in the autumn as they increased
production and moved more stores to the hub and spoke model.
The innovative solution interfaces with EMIS PMR, Omnicell's Robotic Dispensing System and Universal Logistics Management software as well as Victoria OS ordering
software.
The hub operation runs during the day Monday to Friday and produces an average of 33,289 packs per week for just under 9,000 patients, leaving plenty of scope to
ramp up. The hub is currently dispensing 79.7% of repeat prescription original packs requested by the group's busiest stores.
As we begin the near year, experts are still working hard to learn more about COVID-19 to learn how to fight it. We caught up with a lead researcher in Taiwan about new information he has discovered about the origin of the novel virus. There's an unusual pattern found during the COVID investigation process by Atossa Therapeutics called genetic cluster.
Let's found out what Dr. Steven Quay and Fox News has to say about it.
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Komondor is thought to have originated in Hungary more than 500 years ago. It still retains the mantle, somewhat unusual weight consists of white rope, which makes the dog look like animals so it was bred to protect: the sheep.
A. History and Background
The earliest record of the Komondor date back to 1555, but is expected to multiply there much earlier. Its main role is to guard the flock against predators. They are so effective, in fact, that some believe is fully depleted populations of wolves in Hungary.
Komondor is derived from Owtcharka, the leggy Russian, who was brought to Hungary by the Huns. Dogs bear such a striking resemblance to the sheep Racka or Magyar, with curly wool and train like dogs, that they easily mixed with sheep and appears to be part of the flock.
The Komondor was first introduced to the United States in 1933, four years later, the American Kennel Club officially recognized the breed. Since the devastation of World War II, however, the breed was almost destroyed in Europe. Fortunately, dedicated breeders able to revive the popularity of the breed and their numbers.
Komondor is one of the most interesting dog in the show ring, but only the best on display. Thus, the Komondor breed is commonplace throughout the world, except in Hungary. Although there are a few breeders in the U.S. the new generation of pastors who have taken an interest in the Komondor, because it enhances the ability of pastors to keep livestock.
B. Personality and Temperament
Dogs good with livestock and other pets, and are very happy when given the opportunity to watch someone or something. A true guardian, was always protective of his family, but may misinterpret rough play among children as aggression.
It is an independent, calm, and quiet, but can be dominant or stubborn. Komondor is not a dog for the light at heart. In addition, early socialization is important to familiarize Komondor with strange people and dogs.
C. Physical characteristics
In keeping with the system used for referring to various types of cancers wherein the disease is named after the organ which it afflicts first, breast cancer is so named because its point of origin is the human breast, specifically along the length of the ducts.