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The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a second "bivalent" vaccine as a Covid-19 booster. The updated booster vaccine made by Pfizer/BioNTech, targeting two coronavirus variants, has been approved for use in individuals aged 12 years and above. In each dose of the booster vaccine, 'Comirnaty bivalent Original/Omicron', half of the vaccine (15 micrograms) targets the original virus strain and the other half (15 micrograms) targets Omicron (BA.1). Dr June Raine, MHRA chief executive said: "I am pleased to announce that we now have a second approved vaccine for the UK Autumn booster programme. The clinical trial of the Pfizer/BioNTech bivalent vaccine showed a strong immune response against the Omicron BA.1 variant as well as the original strain. Bivalent vaccines are helping us to meet the challenge of an ever-evolving virus, to help protect people against Covid-19 variants. We have in place a comprehensive safety surveillance strategy for all UK-approved Covid-19 vaccines, and this will include the updated booster we approved today."

The Joint Committee on Vaccination and Immunisation (JCVI) has advised booster vaccination to be offered this autumn (2023) for those at higher risk of severe Covid-19 in its interim advice to government on the coronavirus (COVID-19) vaccination programme for 2023. The JCVI also advised that for a smaller group of people, such as those who are older and those who are immunosuppressed, an extra booster vaccine dose in the spring should also be planned for. Professor Wei Shen Lim, Chair of Covid-19 vaccination on the JCVI, said: "The Covid-19 vaccination programme continues to reduce severe disease across the population, while helping to protect the NHS. That is why we have advised planning for further booster vaccines for persons at higher risk of serious illness through an autumn booster programme later this year. We will very shortly also provide final advice on a spring booster programme for those at greatest risk."

Covid-19 vaccine makers are shifting gears and planning for a smaller, more competitive booster shot market after delivering as many doses as fast as they could over the last 18 months. Executives at the biggest Covid vaccine makers including Pfizer and Moderna said they believe most people who wanted to get vaccinated against Covid have already done so - more than five billion people worldwide. In the coming year, most Covid vaccinations will be booster shots, or first inoculations for children, which are still gaining regulatory approvals around the world, they said. Pfizer, which makes its shot with Germany's BioNTech and Moderna still see a major role for themselves in the vaccine market even as overall demand declines. Upstart US vaccine maker Novavax and Germany's CureVac, which is working with GlaxoSmithKline, are developing vaccines they hope to target at the booster market. The roles of AstraZeneca and Johnson & Johnson, whose shots have been less popular or effective, are expected to decline in this market.

The government announced today (November 19) that it would add booster shots to the Covid-19 pass for outbound international travel, though it added they would not be added to the domestic pass at this time. The Department of Health and Social Care said travellers who have had a booster or a third dose would be able to demonstrate their vaccine status through the NHS Covid Pass from today. The addition will enable those who have had their booster or third dose to travel to countries including Israel, Croatia and Austria who have already introduced a time limit for the Covid-19 vaccine to be valid for quarantine free travel. Booster and third doses will not be added to the domestic 'Covid Pass' as it is not a current requirement for individuals to receive booster doses to qualify as fully vaccinated. A booster is not necessary to travel into England.

As part of efforts to streamline spending and enhance resource allocation within the healthcare system, the NHS has chosen to cease providing the free vaccinations for all, which were initially introduced in 2020. Approximately 12 million British citizens will not have access to free flu vaccinations and Covid-19 boosters during the upcoming winter, according to NHS. Furthermore, the NHS plans to defer flu vaccine distribution to October, aiming to heighten protection for those aged 65 and older and other eligible groups in the high-risk winter months. However, this has stirred panic among pharmacies, given their advanced planning based on the initial start date of September 1 for vaccinations. On Tuesday (Aug. 8), the Joint Committee on Vaccination and Immunisation (JCVI) released NHS guidelines indicating that Covid-19 booster shots, starting from autumn, will not be provided to individuals aged 50 to 64 who are in otherwise good health. Similar guidance had already been released for flu, rendering 12 million middle-aged Britons ineligible for free jabs, JCVI said. Prior to the pandemic, influenza vaccinations were available to healthy adults aged over 65, alongside children and younger adults with medical conditions. Amidst the pandemic, the distribution of flu vaccinations was expanded to include individuals aged 50 to 64, in alignment with the criteria for Covid-19 boosters.

The Department of Health and Social Care (DHSC) is encouraging people to come forward for their first and/ or second dose of the Covid vaccine before the free offer ends on Friday (30 June). The NHS's world-leading vaccination programme has so far delivered over 146 million Covid jabs. Building on the success of autumn and spring booster programmes, a seasonal, targeted vaccination offer will remain open for those most at risk, in line with advice from the Joint Committee on Vaccination and Immunisation (JCVI). Health Minister Maria Caulfield said: "As we live with Covid without restrictions on our freedoms, it is right that we move towards a more targeted vaccination offer that prioritises those most at risk, so we can focus our efforts on cutting waiting lists for NHS treatment - one of the Prime Minister's top five priorities. As the offer for any adult to get a Covid vaccine comes to an end on 30 June, I would urge those who have not yet come forward to choose to have the first and second Covid vaccine. It takes minutes to get your jab and thousands of sites are open across England." This year's spring booster programme continues to gather pace, with over two million eligible people receiving their vital top-up dose.

Prime minister Borris Johnson visited a Boots vaccination site in his west London constituency of Uxbridge on Monday (January 10) - as the pharmacy chain celebrates its anniversary of supporting the NHS Covid-19 vaccination drive. During the visit, the prime minister met with some pharmacists who have been administering Covid-19 booster jabs to patients. Since opening the first vaccination site at its Halifax store in January 2021, Boots UK has administered over 1.4 million Covid-19 jabs, and continues to offer booster doses at over 80 pharmacies, the company said in a statement. Continuing its support for the Covid-19 booster programme, Boots has doubled appointment capacity and added a small number of new sites since December 2021. Boots vaccination programme director Nick Sunderland said: "We are so proud of our pharmacists who have worked incredibly hard to support the national effort to accelerate the Covid-19 booster vaccination programme.

Healthcare workers, including community pharmacy staff, can book their Covid-19 booster vaccination through the National Booking Service from Wednesday (September 7) onwards. NHS England has announced that around seven million people, including those aged 75 and over, people who are immunosuppressed and health and care workers will be able to book an appointment for their Covid-19 booster vaccinations online or by calling 119. Eligible staff are encouraged to book an appointment for a booster dose as soon as possible, provided it has been at least three months since their last dose of the vaccine. "For other eligible patients (not health and care workers), invitations are being sent out and will be landing on their doormats from Wednesday 7th September inviting people to book their appointment for the following week without delay. The NHS will contact people when it is their turn to book in for the vaccine - there will be no need for patients to contact the NHS," said PSNC.

NHS chief executive Amanda Pritchard joined over 17 million people in England by taking her Covid-19 booster dose on Monday (December 6) whilst encouraging people to take their top-up jab. The NHS boss got a dose in each arm as she also received her flu vaccine from pharmacist Bhaveen Patel at the Junction Pharmacy in Brixton. Pritchard later posted a video on Twitter, thanking the team in the south London community pharmacy. Ahead of the first anniversary of the NHS delivering the first Covid-19 vaccine in the world on Wednesday (December 8), Pritchard thanked the "incredible efforts" of NHS staff and volunteers who worked hard to protect millions of people. Almost 100 million jabs have been delivered in England since December 8, 2020, including over 17 million booster vaccines. Expressing her delight after taking the booster dose, Pritchard said: "The booster jab was quick, easy and I now have extra protection against the virus."

The new NHS chief executive Amanda Pritchard acknowledged and thanked health service staff and volunteers for their "extraordinary team effort" while the country fights Omicron. Pritchard, who took up the post in July, praised the efforts of doctors, nurses, therapists, porters and other staff who have worked hard to recover services impacted by the Covid-19 pandemic. In her first Christmas message as the NHS chief, she praised all those involved in the NHS Covid vaccination programme which delivered more than 7 million jabs, including boosters, in the last 10 days alone. She said: "We've had another extraordinary 12 months. "From January when hospitals admitted 100,000 patients with Covid in a single month, while also delivering the world-class NHS covid vaccination programme; to receiving the George Cross during the summer, marked by a service at St Paul's, pulling out all the stops to make progress on recovering backlogs of care; and now facing the uncertainty of Omicron and winter pressures.

Britain's Covid booster campaign is set to kick off this September, after the country became the first in the world to approve an Omicron-adapted shot. Around 26 million people in Britain are estimated to be eligible for an autumn Covid-19 booster, having had at least two Covid vaccine doses already, a UK Health Security Agency (UKHSA) spokesperson said. The preference is to deploy what is known as a "bivalent vaccine" that targets both the original virus and the Omicron variant through the autumn campaign, but that will depend on the health regulator (MHRA) approving such shots and the state of vaccine supplies. The UK's Joint Committee on Vaccination and Immunisation (JCVI) has advised boosters should be given to over-50s, individuals in clinical risk groups, frontline workers and care-home staff ahead of the winter, when respiratory viruses are typically at their peak. On Monday (August 15), the MHRA gave Moderna's bivalent shot conditional approval. The endorsement of the vaccine is based on data that showed it produced a marginally better immune response against some Omicron variants, versus the original novel coronavirus - although whether that translates into stronger protection against serious disease is unclear.

Well Pharmacy is urging those eligible to take up the offer of a further Covid booster jab this spring. Adults aged 75 years and over and anyone over 5 years old and are immunosuppressed - such as those who are undergoing chemotherapy or have had an organ transplant - are entitled to have a further Covid booster jab from mid-April, said one of the UK's largest community pharmacy chains. Taking part in the vaccination programme again, Well Pharmacy is encouraging people to book another booster as soon as they are contacted by the NHS - which should be at least six months after their previous booster. The national booking site for those eligible opens this week. The jabs have been updated since the vaccines were introduced to now target newer strains of Covid-19, Well said in a press release issued on Wednesday, 5 April. Thousands of people are still testing positive for Covid each week according to Government data, and - while hospitalisations are down - a large number of people are still being hospitalised with Covid, so getting jabbed is as important as ever. And the Joint Committee on Vaccination and Immunisation (JCVI) recently confirmed that hospital admissions last autumn highlighted that the risk of becoming seriously ill from coronavirus was noticeably higher in people over 75.

For the first time, Covid-19 vaccines will be available for purchase from pharmacies in Britain from April 1. As revealed by The Times, Boots is set to launch a private vaccination service next week to ensure that people "remain ready to respond to this constantly evolving and unpredictable virus." Under the NHS national immunization programme (NIP), Covid booster vaccines are only offered to those at high risk, including over-65s or patients with weakened immune systems. From April 1, anyone aged 12 or over can get the Pfizer-BioNTech Covid-19 vaccine at 50 Boots stores for £98.95. While it's highly unlikely for healthier young adults to experience severe Covid-19, getting the single-dose vaccine can protect them from discomforting symptoms like coughs and sore throats. A spokesperson for Boots told the publication that their private service is the extension of their existing delivery of Covid-19 vaccinations for the NHS.

As the government today (November 15) announced plans to expand Britain's booster programme for Covid-19 vaccinations to cover all adults aged over 40, NHS Confederation welcomed the move. The announcement follows the Joint Committee on Vaccination and Immunisation (JCVI) statement that all healthy adults aged 40-49 should be offered a booster, six months after their second dose, and that 16 and 17 year olds should be invited to have a second dose. Accepting the JCVI's advice, health and social care secretary Sajid Javid said: "All 4 parts of the UK intend to follow the JCVI's advice. "We know immunity to Covid-19 begins to wane after 6 months and new data published today shows a third dose boosts protection against symptomatic infection to more than 90% - this highlights just how important it is that everyone eligible gets their top-up jabs as soon as possible."

70 per cent of community pharmacies still waiting for government nod to start Covid booster jabdesc-Nearly 70 per cent of community pharmacies in England that offered to participate in the Covid-19 booster programme are still waiting for approval or have been refused, ministers admitted on Monday (December 13). The Liberal Democrats' health spokesperson, Daisy Cooper, exposed the low approval rate and long delays through a written parliamentary question to the health secretary as to "how many community pharmacies were providing Covid-19 vaccinations as of 3 December 2021."In response vaccines minister Maggie Throup said: "As of the end of September 2021, 4,733 contractors submitted 5,376 expressions of interest to take part in the booster vaccination programme, with 1,454 accepted."She added: "As of 3 December 2021, 1,336 community pharmacy vaccination sites were actively providing the service." Some applications were decided by NHS England rather than the Department of Health and Social Care (DHSC).

It is not sustainable to give Covid-19 booster shots every three to six in the long term, Britain's chief scientific adviser said on Tuesday (January 4), even though the booster rollout is needed in the short term to combat the Omicron variant. "It would be a situation that isn't tenable to say everyone's going to need to be having another vaccine every three or six months. "That's not the long-term view of where this goes to," Patrick Vallance said at a news conference, adding that annual booster shots against Covid-19 might be necessary, similar to flu shots.

Covid-19 booster jab can now be administered sooner than six months after the second dose to certain vulnerable people as guideline in the UK Health Security Agency (UKHSA) Green Book has been updated. With the change in the guidance, care home residents who have been given their second vaccine dose at different times will be able to be jabbed in the same session, as long as it has been at least five months since their last dose. It may also help with other vulnerable groups, such as housebound patients to have their flu and Covid-19 vaccines at the same time. The move will also benefit those who are about to receive immunosuppressive treatment as they can get the booster from a minimum of four months after their second dose. Health secretary Sajid Javid said: "This updated guidance will ensure healthcare professionals have the necessary flexibility in the booster programme, allowing more vulnerable people to be vaccinated where it makes operational sense to do so." Vaccines minister Maggie Throup also encouraged eligible people to book their booster jab and secure protection.

Covid-19 vaccines made by Pfizer and Moderna that use mRNA technology provide the biggest boost to antibody levels when given 10-12 weeks after the second dose, a new study has found. The "COV-Boost" study was cited by UK officials when they announced that Pfizer and Moderna were preferred for use in the country's booster campaign, but the data has only been made publicly available now. The study found that six out of the seven boosters examined enhanced immunity after initial vaccination with Pfizer-BioNTech's vaccine, while all seven increased immunity when given after two doses of AstraZeneca's vaccine. "A third dose will be effective for many of the vaccines we've tested and in many different combinations," Professor Saul Faust, an immunologist at the University of Southampton and the trial's lead, told the media.

NHS England has agreed to offer an additional payment of £2.50 per jab if pharmacies would be willing to extend the duration of their COVID-19 vaccination contract until 31st August 2024. Pharmacies currently providing the autumn vaccination are asked to let their local commissioner know, by 22nd February 2024, if they can provide cover for a potential Spring booster programme, if the Joint Committee on Vaccination and Immunisation (JCVI) advises in their guidance expected to be published soon. NHS figures showed that more than 3,500 community pharmacies signed the contract to deliver COVID-19 vaccinations between 1 September 2023 and 31 March 2024, as part of the autumn booster programme. The health service is hoping that most of these pharmacies will be able to continue to support the Spring campaign, which will run from 1 April 2024 to 31st August 2024, to help protect the nation's most vulnerable populations. For the Spring campaign only, pharmacies would be offered an extra £2.50 per jab in addition to the existing item of service fee of £7.54, NHS England said.

Recent uptake of COVID-19 vaccine booster doses in Europe has been "rather disappointing," an official said on Thursday (November 24), amid concerns that protection against severe cases of the disease could weaken during the winter. The European average rate of re-vaccination, or receiving booster doses, was only 29 per cent in the groups of people considered to be at highest risk, such as the elderly and immunocompromised. "It is of concern that those most at risk of hospitalisation or severe COVID are not adequately protected," the European Medicines Agency's head of health threats and vaccines strategy, Marco Cavaleri, told a news briefing. Though there have not been major increases in COVID-19 case rates in recent weeks, Cavaleri said that could change during the colder winter months.