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manu1234515

Best Paediatric Hospital in Mumbai | Best Children Hospital in Mumbai- Apollo Hospitals... - 0 views

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    Apollo Hospitals is the best pediatric hospital in Navi Mumbai providing paediatric super specialities under one roof.
Dr.Ravichandra Karkal

WORKUP AND DIAGNOSIS OF A SOLITARY THYROID NODULE from Townsend: Sabiston Textbook of S... - 3 views

  • Rapid growth and signs of possible invasion, such as pain or hoarseness, are most suggestive, but not conclusive of malignancy
  • Clinical groups with the highest risk for malignancy in a thyroid nodule are children, males, adults younger than 30 or older than 60 years, and those exposed to radiation therapy, especially during childhood
  • history of specific endocrine disorders
    • Dr.Ravichandra Karkal
       
      medullary carcinoma, MEN 2, or papillary thyroid cancer (PTC), or a history of familial polyposis, including Gardner's syndrome.
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  • Serum Tg has been reported as useful in predicting a well-differentiated carcinoma
  • Radioisotope Scanning
  • radionuclide scans allow assessment of thyroid function.
  • Technetium pertechnetate (99mTc) is taken up rapidly by the normal activity of follicular cells. It is trapped by follicular cells, but not organified. 99mTc has a short half-life and low radiation dose. Its rapid absorption allows quick evaluation of increased uptake (so-called hot) or hypofunctioning (so-called cold) areas of the thyroid.
  • 123I and 131I iodine scintigraphy is also used to evaluate the functional status of the gland
  • Advantages of scanning with 123I include a low dose of radiation (30 mrad) and short half-life.
  • 123I is a good choice for evaluating suspected lingual thyroids or substernal goiters.
  • 131I has a longer half-life (8 days) and emits higher levels of β-radiation. 131I is optimal for imaging thyroid carcinoma.
  • screening modality of choice for the evaluation of distant metastasis.
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