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Dr. John Bureau DC

Taking Folic Acid Supplements Before Conception Linked To Reduced Risk Of Premature Birth - 0 views

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    ScienceDaily (May 12, 2009) - Taking folic acid supplements for at least a year before conception is associated with reduction in the risk of premature birth, according to a study by Radek Bukowski (from the University of Texas Medical Branch, United States of America) and colleagues. Although most pregnancies last about 40 weeks, many babies (for example around 12% in the United States) are born before 37 completed weeks of pregnancy. Babies born prematurely are less likely to survive than full-term babies and are more likely to have breathing difficulties and learning or developmental disabilities. Currently, there are no effective methods of prevention or treatment of premature (preterm) birth, but previous studies have suggested that lower concentrations of folate (folic acid) are associated with shorter duration of pregnancy. Bukowski and colleagues therefore tested this idea, by analyzing data collected from a cohort of nearly 35,000 pregnant women. The results of this study showed that taking folate supplements for at least one year before conception was associated with a 70% reduction in spontaneous premature birth between 20 and 28 weeks (a reduction from 0.27% to 0.04%), and a 50% reduction between 28 and 32 weeks (reduction from 0.38% to 0.18%), as compared to the rate of preterm birth when mothers did not take additional folate supplementation. Folate supplementation for less than a year before conception was not linked to a reduction in the risk of premature birth in this study, and folate supplementation was not associated with any other complications of pregnancy. In a related commentary also published in this week's PLoS Medicine, Nicholas Fisk from the University of Brisbane, Australia, and colleagues (who were not involved in the original study) say "Methodologically, the study has several strengths... It is based on a huge dataset, with prospective recording of dietary supplements and potential confounders, and gestational age determined accu
Matti Narkia

An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day - Entrez PubMed - 0 views

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    Grant WB, Garland CF, Gorham ED. \nAn estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day.\nRecent Results Cancer Res. 2007;174:225-34.\nPMID: 17302200 [PubMed - in process]
Matti Narkia

Sloan-Kettering - Garlic - 0 views

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    Derived from the bulb or clove of the plant. Garlic is used as a spice and to treat hyperlipidemia, hypertension, atherosclerosis, cancer, and infections. Processing can have a substantial effect on the chemical content in garlic; the volatile oil components are sensitive to heat and certain enzymes are acid-labile. Several oral garlic formulations are available, and clinical studies have addressed a variety of the proposed claims. Placebo-controlled trials on the cholesterol lowering effect of garlic yielded mixed results (16) (17) (18) (21) (22) (26). Studies evaluating the antithrombotic effects repeatedly have shown modest reduction in platelet aggregation, but varying levels of fibrinolytic activity. Research shows mixed effects with regard to reductions in blood glucose, blood pressure, or risk of cardiovascular disease (23). Frequently reported adverse events include bad breath, headache, fatigue, GI upset, diarrhea, sweating, and possible hypoglycemia (9). Because garlic is known to decrease platelet aggregation and potentially elevate the INR, it should not be used with anticoagulants or in patients with platelet dysfunction (15). Garlic appears to induce cytochrome p450 3A4 and may enhance metabolism of many medications (e.g. cyclosporin and saquinavir) (12). An analysis of several case-control studies in Europe suggests an inverse association between garlic consumption and risk of common cancers (25).
Matti Narkia

DHA reduces tumor growth - Life Extension Update - 0 views

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    Mice injected with cancer cells experienced significantly elevated levels of C-reactive protein, white blood cells, and lipid peroxidation compared with control mice. These levels were reduced in animals that received cisplatin and/or DHA. While treatment with 125 mg/kg DHA inhibited tumor growth by 38 percent compared to untreated animals, 250 mg/kg suppressed tumor growth by 79 percent, which was a greater effect than that of cisplatin alone (which was associated with a 55 percent reduction). The combination of DHA and cisplatin resulted in an 81 percent inhibition of growth, while reducing elevated white blood cell levels (leukocytosis) to normal levels. Treatment with the higher dose of DHA alone was associated with a similar reduction in white blood cells, which, when elevated, are associated with tumor growth. A strong relationship was observed between tumor growth and white blood cell levels as well as C-reactive protein levels. In another experiment with rats treated with cisplatin, the addition of 250 mg/kg DHA prevented lethal kidney toxicity in 88 percent of the animals that received it, while none of the rats that received cisplatin alone survived.
Dr. John Bureau DC

Medical News: Heart Patients Should Walk Often, Walk Far - in Primary Care, Exercise & Fitness from MedPage Today - 0 views

  • LITTLE FALLS, N.J., May 13 -- Exercise regimens that burn more calories over less-intense periods of exercise can increase weight loss and reduce cardiovascular risk factors better than standard cardiac rehabilitation programs, researchers have found. Action Points  Explain that walking more at a slower pace improved weight loss and cardiac risk factors better than standard cardiac rehabilitation programs.Note that current cardiac rehabilitation guidelines were written when deconditioning after lengthy hospital stays was common, which is no longer the case. In a randomized trial, overweight patients who exercised more but with less intensity lost twice as much weight as those on typical cardiac rehab regimens and had greater reductions in markers of metabolic syndrome, according to Philip A. Ades, M.D., of the University of Vermont, and colleagues. "High-calorie-expenditure exercise is superior to standard cardiac rehabilitation exercise in accomplishing weight loss and favorably altering cardiometabolic risk factors, particularly insulin resistance, in overweight patients with coronary heart disease," the researchers reported online in Circulation: Journal of the American Heart Association.
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    LITTLE FALLS, N.J., May 13 -- Exercise regimens that burn more calories over less-intense periods of exercise can increase weight loss and reduce cardiovascular risk factors better than standard cardiac rehabilitation programs, researchers have found. In a randomized trial, overweight patients who exercised more but with less intensity lost twice as much weight as those on typical cardiac rehab regimens and had greater reductions in markers of metabolic syndrome, according to Philip A. Ades, M.D., of the University of Vermont, and colleagues. "High-calorie-expenditure exercise is superior to standard cardiac rehabilitation exercise in accomplishing weight loss and favorably altering cardiometabolic risk factors, particularly insulin resistance, in overweight patients with coronary heart disease," the researchers reported online in Circulation: Journal of the American Heart Association.
Matti Narkia

Fish Oil Consumption and Reduction of Arterial Disease -- Vanschoonbeek et al. 133 (3): 657 -- Journal of Nutrition - 0 views

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    Here we propose that the beneficial effect of (n-3) PUFA diet is related to down-regulation of the mutually positive interactions of platelet activation and coagulation. In addition, we consider the possibility that the dietary effect on hemostatic and lipid factors involves transcription regulation of multiple genes, perhaps in a subject-dependent manner. Fish oil consumption and reduction of arterial disease. Vanschoonbeek K, de Maat MP, Heemskerk JW. J Nutr. 2003 Mar;133(3):657-60. Review. PMID: 12612132
Matti Narkia

Antioxidant vitamins may protect against female cancer - 0 views

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    Increased intakes of vitamins C and E and beta-carotene may reduce the risk of cancer of the uterus, according to a new review and meta-analysis of the science to date. Writing in Cancer Causes and Control, US scientists report that for every 1,000 microgram increase per 1,000 kcal of diet of beta-carotene was associated with a 12 per cent reduction in the risk of endometrial cancer.
Matti Narkia

Vitamin K2 and coronary plaque - Wellsphere - 0 views

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    The vitamin K2 story, though still preliminary, is becoming increasingly interesting from the perspective of CT heart score reduction. The origin of this concept came from some unexpected observations. One, the observation that osteoporosis (lack of bone calcium that leads to fractures) arises from deficiency of vitamin K2. Two, deficiency of K2 leads to unrestrained calcium deposition in animal models, leading to heart attack in just weeks.
Matti Narkia

Consuming A Little Less Salt Could Mean Fewer Deaths - 0 views

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    ScienceDaily (Mar. 11, 2009) - For every gram of salt that Americans reduce in their diets daily, a quarter of a million fewer new heart disease cases and over 200,000 fewer deaths would occur over a decade, researchers said at the American Heart Association's 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.
Matti Narkia

Vitamin K2, but not K1, effective for heart health benefits: Study - 0 views

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    Increased intakes of vitamin K2, but not vitamin K1, may decrease the risk of coronary heart disease in postmenopausal women, says a new study.\nFor every 10 microgram increase in the amount of vitamin K2 consumed, researchers from the Netherlands report a 9 per cent reduction in the risk of developing coronary heart disease (CHD).
Matti Narkia

Mushrooms, green tea may lower breast cancer risk - 0 views

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    NEW YORK (Reuters Health) - Women who get plenty of mushrooms and green tea in their diets may have a lower risk of developing breast cancer, new study findings suggest. The study, of more than 2,000 Chinese women, found that the more fresh and dried mushrooms the women ate, the lower was their breast cancer risk.
Matti Narkia

B Vitamins May Cut Stroke Risk - Neurology (Brain and Nerve) Conditions, Diseases, Medications, Procedures, Tests, Treatment, Prevention, and Prognosis Information on MedicineNet.com - 0 views

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    Feb. 20, 2009 (San Diego) -- High doses of B vitamins may help prevent stroke in high-risk people, new research suggests.\n\nThe finding comes from the Heart Outcomes Prevention Evaluation 2 trial of more than 5,500 men and women with heart disease. Participants were assigned to a daily regime
Matti Narkia

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation - [Clin Nutr. 2004] - PubMed Result - 0 views

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    Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation.\nAviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N, Presser D, Attias J, Liker H, Hayek T.\nClin Nutr. 2004 Jun;23(3):423-33. Erratum in: Clin Nutr. 2008 Aug;27(4):671.\nPMID: 15158307
Matti Narkia

Reductions In Cancer And Overall Mortality Persist 10 Years After Vitamin And Mineral Supplementation - 0 views

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    ScienceDaily (Mar. 24, 2009) - Individuals who took a dietary supplement called "factor D", which included selenium, vitamin E, and beta-carotene, continued to have lower gastric cancer and overall mortality 10 years after supplementation ceased compared with individuals who did not take the supplements, according to long-term follow-up data from the randomized, double-blind General Population Nutrition Intervention Trial in Linxian, China.
Matti Narkia

Selenium linked to lower skin cancer risks - 0 views

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    Higher blood levels of selenium may reduce the incidence of skin cancer by about 60 per cent, according to a new study from Dutch and Australian researchers. Writing in Cancer Epidemiology, Biomarkers & Prevention, the researchers report that the mineral was associated with reduced risks of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). On the other hand, blood levels of carotenoids and alpha-tocopherol (vitamin E) were not associated with any influence on skin cancer risks, report the researchers from Queensland Institute of Medical Research, the University of Queensland, and Maastricht University.
Dr. John Bureau DC

Medical News: AAN: Epilepsy Drug Not Effective for Chronic Headache - in Meeting Coverage, AAN from MedPage Today - 0 views

  • SEATTLE, April 30 -- The epilepsy drug levetiracetam (Keppra) does not appear to be effective for prevention of chronic daily headache, researchers said here. Action Points  Explain that the epilepsy drug levetiracetam did not significantly increase the headache-free rate for patients with chronic daily headache compared with placebo.Note, however, that there was a significant reduction in disability and reduced pain severity in the treatment group, and the findings show that there is a subpopulation of chronic daily headache patients for whom levetiracetam remains a therapeutic option.Note that this study was published as an abstract and presented orally at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. Levetiracetam drug achieved a 3.9% increase in headache-free performance over placebo, but the trend did not reach statistical significance, Roy Beran, M.D., of the University of New South Wales, and colleagues reported at the American Academy of Neurology meeting.
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    SEATTLE, April 30 -- The epilepsy drug levetiracetam (Keppra) does not appear to be effective for prevention of chronic daily headache, researchers said here. Levetiracetam drug achieved a 3.9% increase in headache-free performance over placebo, but the trend did not reach statistical significance, Roy Beran, M.D., of the University of New South Wales, and colleagues reported at the American Academy of Neurology meeting.
Matti Narkia

Fish consumption and risk of major chronic disease in men. - Am J Clin Nutr. 2008 Dec - 0 views

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    Fish consumption and risk of major chronic disease in men. Virtanen JK, Mozaffarian D, Chiuve SE, Rimm EB. Am J Clin Nutr. 2008 Dec;88(6):1618-25. PMID: 19064523 doi:10.3945/ajcn.2007.25816 Conclusions: Modest fish consumption was associated with a lower risk of total cardiovascular disease, consistent with cardiac mortality benefits but not with total cancer or overall major chronic disease; n-6 fatty acid consumption did not influence these relations.
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