Group items matching

in title, tags, annotations or url

Hospitals and healthcare providers across the UK have been notified about the shortage of an anti-inflammatory medicine caused by a manufacturing failure. The Department of Health and Social Care (DHSC) on Friday (3 May) issued a National Patient Safety Alert stating that Erelzi 50mg solution for injection in pre-filled pen will be out of stock from early May until mid-July 2024. "The supply issues have been caused by a manufacturing failure resulting in delays in production and the implementation of global allocations," it said. However, it noted that homecare providers (Alcura, Healthnet and Sciensus) have sufficient stock to supply existing patients until mid/late May 2024. Although Erelzi 50mg pre-filled syringes (PFS) are still available, they cannot support a full increase in demand, the DHSC warned.

Good news for patients whose epilepsy cannot be controlled by standard anti-seizure drugs! Next month, NHS England will introduce a cutting-edge laser beam therapy that can prevent seizures in these individuals. Known as Laser Interstitial Thermal Therapy (LITT), the advanced treatment targets the part of the brain causing seizures without the need for invasive surgery, the health service said. The new fibre optic laser therapy is being offered at King's College Hospital in London and The Walton Centre in Liverpool. Starting from June, it will be gradually extended to eligible patients across England. Each year, it is expected to benefit up to 50 epilepsy patients in England who are resistant to standard anti-seizure medications. "This groundbreaking new treatment will change the lives of those with severe epilepsy improving quality of life and providing much-needed assurance," said Andrew Stephenson, Minister of State for Health.

Many of us drink alcohol on a regular basis, and when it comes to the weekend many of us have been known to overindulge a little. For the most part we understand the dangers of alcohol. We have an understanding that it can damage our liver, exacerbate mental health conditions and lead to addiction, with private alcohol treatment one of the few pathways to recovery. However, there are also many other effects that we may not be quite as familiar with, but it is important to know about them, particularly if you are a heavy drinker. Among some of the more common effects you may not be aware of, include… Disruption of REM Sleep Often we think alcohol gives us a better night's sleep, knocking us out for the count. However, while it does aid falling asleep, the quality of that sleep is significantly harmed. It disrupts the normal sleep cycle by reducing the time spent in rapid eye movement sleep, a stage that is important for memory consolidation and cognitive function. This sleep is less restorative and is why we often feel groggy and tired the following day.

Urethroplasty is a surgical procedure used to reconstruct the urethra to address issues such as urethral strictures. The types of surgeries vary and depend on the location, cause, and length of the stricture. Most surgeries typically take between 3 to 6 hours to complete.

In the next 10 years, the incidence of first-time stroke cases in the UK is projected to increase by 60 per cent, costing the government £75bn in healthcare and lost productivity, a charity has suggested. A new manifesto published by the Stroke Association has urged the next UK government to make stroke "the priority", stressing that the next decade is crucial for stroke prevention, treatment and recovery. Currently, stroke is the UK's fourth biggest killer and a leading cause of disability. On a daily basis, 281 individuals experience a stroke. Next year, the cost of stroke in the UK will be £43 billion. The charity predicted that by 2035, there will be 151,000 hospital admissions due to stroke every year, averaging 414 admissions per day, with 42,000 people estimated to die every year. In 2035, the UK is projected to have 2.1 million stroke survivors, imposing a financial burden of £75 billion on the public purse, nearly half the current NHS budget.

After receiving approval from the National Institute for Health and Care Excellence (NICE), the NHS is preparing to roll out a new combination treatment for brain tumours in children and young people in England. Dabrafenib with trametinib would be the first ever targeted treatment for children (aged 1-17) with gliomas that have a specific genetic mutation, the health service said. The treatment, which can be taken at home, has been found to slow the progression of the disease by over threefold compared to standard chemotherapy in children with low-grade gliomas that have a BRAF V600E mutation. Clinical trials have shown that it causes fewer side-effects than chemotherapy. NICE approved the combination treatment on Wednesday 24 April. It will be available on the NHS in the coming months.

"Anything is possible with focused strength, resilience and determination" said Bhavin Shah, Financial Director at Sigma Pharmaceuticals plc, after completing the annual London Marathon. Shah donned his running gear and completed the 26.2 mile route in a commendable time of 5 hours and 33 minutes, all in support of 'Team George', a cause initiated by his close friend, Jonathan Bracey, who is the EVP of corporate development at Tanner Pharma Group. Bracey started the crowdfunding initiative last year after his 2-year-old son George was diagnosed with a rare cancer (rhabdomyosarcoma) on his liver/bile duct. Sigma Pharmaceuticals directors and staff have played a vital part in helping raise over £52,000 over the last 6 months for 'Team George', which included the London Marathon Charity run on Sunday 21 April 2024. The funds will be donated to four charities that have been instrumental in George's path to overcoming cancer - Rays of Sunshine ward at Kings College Hospital Charity, St Mary's Hospital, Alice's Arc and Great Ormond Street Hospital. For over three months, Shah had been training himself physically and mentally for the marathon run to support his friend's initiative. He joined Bracey in the marathon, along with more than 50,000 other competitors.

Sigma Pharmaceuticals, a leading pharmacy wholesaler and distributor in the UK, has once again demonstrated its commitment to supporting the local community by helping raise over £70,000 for local charitable causes. As per a statement from Watford-based industry leader, they raised £20,000 for Citizens Advice Watford, their selected charity of the year, during the recent Sigma annual conference held in Sun City, South Africa. Additionally, Sigma played a vital part in raising more than £52,000 for 'Team George' at the London Marathon Charity run held on Sunday, 21 April 2024 to support cancer charities. Throughout the year, Sigma will continue to partner with Citizens Advice Watford, a local charity that provides frontline service to the community, giving free, expert and impartial advice and support to 8,000 people a year, many of whom are facing crisis situations. Applauding the work done by this charity, Dr Bharat Shah CBE, Founder and Managing Director at Sigma, said: "It has been eye-opening to learn about the life-changing impact the charity has on the lives of so many people. "We have seen how their expert team works day in and day out to speak up for people who have nowhere else to turn, ensuring they receive the support and services they're entitled to."

Adding to the growing evidence of global medicine shortages, a new study has revealed that the European generic medicines market is "not in shape" to help Europe meet its public health priorities. In the past decade, the rate of generic medicines withdrawals has risen by 12 per cent, while there has been a three per cent decrease in the launch of generic products, as per Teva Pharmaceuticals' recent analysis of IQVIA data. Within the mental therapeutic area, seven per cent of generic products disappeared between 2013 and 2023, while there was a seven per cent decrease in the availability of generic cancer medicines in just six years (2017-2022). These medicines were listed on the Union List of Critical Medicines to help avoid potential shortages, as the European Commission (EC) said this could cause "significant harm to patients and pose important challenges to health systems." While mature generic products constitute the majority of the List, they remain susceptible to withdrawals, despite containing products crucial for safeguarding Europe's public health, the Teva analysis report noted. Since 2013, the number of generic products for the treatment of schizophrenia and bipolar disorder has declined by 25 per cent, with Hungary and Bulgaria experiencing the biggest loss at 83 per cent and 58 per cent respectively.

The outbreak of Burkholderia cepacia complex (Bcc) in the UK, which is associated with contaminated eye gels imported from India, has led to the death of one person, and many others falling ill, according to a government report. Bcc is a group of antibiotic-resistant bacteria that are widely found within the environment. Although it rarely causes infection, it can result in severe ones in individuals with compromised immune systems and those living with cystic fibrosis, the UK Health Security Agency (UKHSA) said. Between January 2023 and February 2024, there were 52 confirmed and six probable cases across the UK linked to the bacteria outbreak, as revealed in the Health Protection Report published by UKHSA. Forty-one of these cases were hospital inpatients, 38 of which were in critical-care settings. Twenty-five cases were considered to have "clinically significant infections attributable to Bcc", out of which 11 had eye infections, nine had respiratory infections and four had bacteremia (bacteria entering the bloodstream). Two individuals with cystic fibrosis (CF) were infected, and while one was treated, the other died, with the report indicating Bcc infection to have "contributed to the death."

The UK based Pharma giant Futura Medical Plc's lead product, Eroxon, a topical Stim-gel is now available on NHS prescription in England and Wales for the treatment of Erectile Dysfunction (ED). The Muti-Drug Resistant (MDR) approved alternative to PDE5i, Eroxon is available as an over-the counter off shelf at retailers like Boots and Superdrug; and is available on NHS prescription in England and Wales as a CE-marked medical device. Erectile dysfunction (ED), also known as impotence, is the inability to get and maintain an erection, typically concerning men over the age of 40 due to both, psychological and physical causes such as anxiety, depression, diabetes, and obesity. According to UK Conformity Assessed (UKCA), the approval of the medication is based on evidence from 2 Phase three clinical studies, which showed that 60 per cent of patients taking Eroxon achieved Minimal Clinically Important Differences (MCID) at 12 weeks.

The Royal Pharmaceutical Society (RPS) on Wednesday announced that it is spearheading a new project, which aims to delve into the root causes of the growing challenge of medicines shortages across the United Kingdom and provide solutions to mitigate its impact on patients and pharmacy practice. A newly formed advisory group, chaired by RPS Fellow Dr. Bruce Warner, is set to convene later this month. The group will have experts from primary and secondary care, patient advocacy groups, the pharmaceutical industry, suppliers, regulatory bodies, governmental representatives, and NHS officials. The group aims to formulate a robust report to provide expert thought leadership and support for the wider debate on UK policy. Their work will be informed by a thorough literature review, stakeholder interviews, online RPS member events, and patient stories.

American pharmaceutical giant Pfizer has received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) for its medication Etrasimod, marketed as Velsipity, used to treat people with moderately to severely active ulcerative colitis. Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the lining of the large intestine (colon) and rectum. The approved recommended dose for Velsipity is one 2 mg tablet to be taken once daily. For the first three days, it is advised to take the medication with food, and subsequently, it can be taken daily either with or without food. According to the regulator, the approval of the medication is based on evidence from two clinical studies, which showed that 26 per cent of patients taking etrasimod achieved clinical remission after 12 weeks of treatment compared with 11 per cent of those receiving placebo. The studies included more than 740 patients aged 16 years and over for whom standard treatment or other treatments did not work well enough or could not be used.

Reacting to recommendations from a UK-first independent review, the Department of Health and Social Care (DHSC) has outlined action to tackle potential bias in the design and use of medical devices. Professor Dame Margaret Whitehead, professor of public health at the University of Liverpool, was appointed to lead the review, which focused on three areas - optical devices such as pulse oximeters, AI-enabled devices, and polygenic risk scores (PRS) in genomics. The DHSC commissioned the medical devices review after concerns were raised that pulse oximeters - widely used during the COVID-19 pandemic to monitor blood oxygen levels - were not as accurate for patients with darker skin tones. There were worries that this could cause delays in treatment if dangerously low oxygen levels in such patients were missed. However, no evidence was found from NHS studies indicating that this differing performance had an impact on patient care. Accepting the report's conclusions, the DHSC has committed to several actions, such as ensuring the safe use of pulse oximeter devices across a range of skin tones within the NHS and eliminating racial bias from data sets employed in clinical studies.

Merseyside Police have appealed for information from the public following the theft of "a large quantity" of medication from a pharmacy in West Derby this week. As per the police report, the burglary occurred in the early hours of Monday, 12 February, at the pharmacy situated on Deysbrook Lane. Authorities were informed at around 9:15 am. Based on the CCTV footage they have recovered, the Merseyside Police revealed that a man entered the pharmacy at around 1.20 am on 12 February and stole a large quantity of medication, including diazepam, codeine, co-codamol, pregabalin, zopiclone. These are prescription-only drugs that could cause "serious harm" if a significant amount is taken, the report said. The suspect, described as a white man of slim build, was wearing a grey coloured tracksuit and glasses, according to the police.

Urethroplasty is a surgical procedure aimed at reconstructing the urethra to address issues such as urethral strictures. The types of surgeries vary and depend on the location, cause, and length of the stricture. Most surgeries take between 3 to 6 hours to complete.

QuickBooks Connection Diagnostic Tool is used to solve the technical errors that come when multiple users try to access files at the same time. Intuit is designed to fix the multiple errors. It works with Windows XP and later versions.

QuickBooks Connection Diagnostic Tool is used to solve the technical errors that come when multiple users try to access files at the same time. Intuit is designed to fix the multiple errors. It works with Windows XP and later versions.For any QuickBooks user, maintaining seamless connectivity between your software, company file, and database server is crucial. However, network hiccups and intricate configurations can disrupt this delicate balance, leading to frustrating errors and downtime. Then the QuickBooks Connection Diagnostic Tool emerges as a powerful ally, offering a streamlined solution to diagnose and remedy these connectivity hurdles. Let's delve into this valuable tool and explore how it can restore smooth communication within your QuickBooks ecosystem. Benefits of Using the Tool: By utilizing the Connection Diagnostic Tool, you can: Pinpoint Connection Issues: The tool provides detailed reports, highlighting the exact cause of any connectivity problems. Resolve Errors Efficiently: Equipped with the diagnosis, you can take targeted steps to resolve the identified issues, saving time and frustration. Prevent Downtime: Proactive use of the tool helps identify potential problems before they disrupt your workflow, ensuring consistent uptime. Simplify Troubleshooting: The user-friendly interface and automated diagnosis make troubleshooting accessible even for users with limited technical expertise.

Intuit is the designer of QuickBooks. When multiple users try to access a company file at the same time an error occurs then to troubleshoot the error Intuit QuickBooks Connection Diagnostic Tool comes into existence and it is free of cost.Then the QuickBooks user maintaining a healthy connection between your software, company file, and database server is essential.Because the Intuit QuickBooks Connection Diagnostic Tool Download Free emerges as a powerful ally, offering a streamlined solution to diagnose and remedy these connectivity hurdles. Let's delve into this valuable tool and explore how it can restore seamless collaboration within your QuickBooks ecosystem. Benefits of Using the Tool: By utilizing the Connection Diagnostic Tool, you can: Pinpoint Connection Issues: The tool provides detailed reports, highlighting the exact cause of any connectivity problems. Resolve Errors Efficiently: Equipped with the diagnosis, you can take targeted steps to resolve the identified issues, saving time and frustration. Prevent Downtime: Proactive use of the tool helps identify potential problems before they disrupt your workflow, ensuring consistent uptime. Simplify Troubleshooting: The user-friendly interface and automated diagnosis make troubleshooting accessible even for users with limited technical expertise.

The PTSD(Post-Traumatic Stress Disorder) and Acute Stress Disorder (ASD) are mental health conditions that can develop after experiencing or witnessing a traumatic event. PTSD vs Acute While they share similarities, there are key differences in their onset, duration, and severity of symptoms. Here's a breakdown: Similarities: Triggering event: Both can be triggered by a traumatic event, like a natural disaster, accident, assault, or witnessing violence. Symptoms: Both can cause symptoms like intrusive thoughts, flashbacks, nightmares, avoidance of reminders, negative thoughts and feelings, hyperarousal, and difficulty sleeping. Differences: Onset: ASD: Symptoms appear within days or weeks after the event and typically last less than a month. PTSD: Symptoms usually develop within 3 months of the event, but can sometimes appear years later. They must persist for at least a month for a diagnosis.

Psoriasis vs Eczema, while both causing itchy, inflamed skin, are distinct conditions with different underlying causes and treatments. Understanding these differences is crucial for proper diagnosis and management. Symptoms: Psoriasis: Thick, red, scaly patches: Often on elbows, knees, scalp, but can affect any area. Silvery scales: Easily removed, revealing inflamed skin beneath. Eczema: Dry, itchy, red patches: Often on inner elbows, knees, hands, face, but can be widespread. Fine, scaling: Less prominent compared to psoriasis. causes: Psoriasis: Autoimmune condition: Immune system mistakenly attacks healthy skin cells, causing rapid growth and buildup. Genetic predisposition: Family history increases risk. Eczema: Atopic dermatitis: Combination of genetic and environmental factors. Dry skin: Major contributing factor. Treatments: Psoriasis: Topical medications: Steroids, retinoids, vitamin D analogues to reduce inflammation and cell growth. Light therapy: Ultraviolet light exposure to slow skin cell production. Eczema: Moisturizers: Regular use hydrates and protects the skin barrier. Emollients: Oil-based creams to soothe dryness and itching. Key Differences: Cause: Psoriasis is autoimmune, while eczema is complex and involves both genetics and environment. Symptoms: Psoriasis typically has thicker scales and less itching, while eczema is drier and itchier.