Britain's booster programme for Covid-19 vaccinations is set to be expanded following advice from scientists.
The government's Joint Committee on Vaccination and Immunisation (JCVI) said today (November 15) that all healthy adults aged 40-49 should be offered a booster, six months after their second dose.
Previously, the booster programme was limited to those aged 50 and over, and the clinically vulnerable.
So far, some 12.6 million people have had a booster dose.
The latest advice comes after the UK Health Security Agency released data from a real-world study which found the booster gave over 90 per cent protection against symptomatic Covid-19 for people aged 50 years and older.
The Joint Committee on Vaccination and Immunisation (JCVI) has advised booster vaccination to be offered this autumn (2023) for those at higher risk of severe
Covid-19 in its interim advice to government on the coronavirus (COVID-19) vaccination programme for 2023.
The JCVI also advised that for a smaller group of people, such as those who are older and those who are immunosuppressed, an extra booster vaccine dose in the spring
should also be planned for.
Professor Wei Shen Lim, Chair of Covid-19 vaccination on the JCVI, said: "The Covid-19 vaccination programme continues to reduce severe disease across the population,
while helping to protect the NHS.
That is why we have advised planning for further booster vaccines for persons at higher risk of serious illness through an autumn booster programme later this year.
We will very shortly also provide final advice on a spring booster programme for those at greatest risk."
Well Pharmacy is urging those eligible to take up the offer of a further Covid booster jab this spring.
Adults aged 75 years and over and anyone over 5 years old and are immunosuppressed - such as those who are undergoing chemotherapy or have had an organ
transplant - are entitled to have a further Covid booster jab from mid-April, said one of the UK's largest community pharmacy chains.
Taking part in the vaccination programme again, Well Pharmacy is encouraging people to book another booster as soon as they are contacted by the NHS - which
should be at least six months after their previous booster.
The national booking site for those eligible opens this week.
The jabs have been updated since the vaccines were introduced to now target newer strains of Covid-19, Well said in a press release issued on Wednesday, 5 April.
Thousands of people are still testing positive for Covid each week according to Government data, and - while hospitalisations are down - a large number of people
are still being hospitalised with Covid, so getting jabbed is as important as ever.
And the Joint Committee on Vaccination and Immunisation (JCVI) recently confirmed that hospital admissions last autumn highlighted that the risk of becoming
seriously ill from coronavirus was noticeably higher in people over 75.
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a second "bivalent" vaccine as a Covid-19 booster.
The updated booster vaccine made by Pfizer/BioNTech, targeting two coronavirus variants, has been approved for use in individuals aged 12 years and above.
In each dose of the booster vaccine, 'Comirnaty bivalent Original/Omicron', half of the vaccine (15 micrograms) targets the original virus strain and the other
half (15 micrograms) targets Omicron (BA.1).
Dr June Raine, MHRA chief executive said: "I am pleased to announce that we now have a second approved vaccine for the UK Autumn booster programme. The clinical
trial of the Pfizer/BioNTech bivalent vaccine showed a strong immune response against the Omicron BA.1 variant as well as the original strain.
Bivalent vaccines are helping us to meet the challenge of an ever-evolving virus, to help protect people against Covid-19 variants. We have in place a comprehensive
safety surveillance strategy for all UK-approved Covid-19 vaccines, and this will include the updated booster we approved today."
The Joint Committee on Vaccination and Immunisation (JCVI) on Thursday (May 19) said that an anticipated autumn Covid booster campaign would be aimed at
people aged over 65, care home residents, frontline health and social care workers and all adults in a clinical risk group.
The UK is offering a spring booster to the over-75s, care home residents and immunosuppressed people, and ministers have spoken openly of plans for a further
booster campaign in the autumn.
In interim advice, the JCVI stopped short of recommending another shot for all adults, though said the advice would be reviewed and updated.
"The JCVI's current view is that in autumn 2022, a Covid-19 vaccine should be offered to: residents in a care home for older adults and staff; frontline health
and social care workers; all those 65 years of age and over; and adults aged 16 to 64 years who are in a clinical risk group," the UK Health Security Agency said
in a statement.
Prime minister Boris Johnson, who was fiercely criticised for his handling of the early stages of the pandemic, lifted Covid restrictions in England in February,
crediting Britain's quick initial vaccine rollout and the rollout of boosters with breaking the link between cases and deaths.
Covid-19 vaccine makers are shifting gears and planning for a smaller, more competitive booster shot market after delivering as many doses as fast as they
could over the last 18 months.
Executives at the biggest Covid vaccine makers including Pfizer and Moderna said they believe most people who wanted to get vaccinated against Covid have already done so - more than five billion people worldwide.
In the coming year, most Covid vaccinations will be booster shots, or first inoculations for children, which are still gaining regulatory approvals around the world, they said.
Pfizer, which makes its shot with Germany's BioNTech and Moderna still see a major role for themselves in the vaccine market even as overall demand declines.
Upstart US vaccine maker Novavax and Germany's CureVac, which is working with GlaxoSmithKline, are developing vaccines they hope to target at the booster market.
The roles of AstraZeneca and Johnson & Johnson, whose shots have been less popular or effective, are expected to decline in this market.
It is not sustainable to give Covid-19 booster shots every three to six in the long term, Britain's chief scientific adviser said on Tuesday (January 4), even though the booster rollout is needed in the short term to combat the Omicron variant.
"It would be a situation that isn't tenable to say everyone's going to need to be having another vaccine every three or six months.
"That's not the long-term view of where this goes to," Patrick Vallance said at a news conference, adding that annual booster shots against Covid-19 might be necessary, similar to flu shots.
Healthcare workers, including community pharmacy staff, can book their Covid-19 booster vaccination through the National Booking Service from Wednesday
(September 7) onwards.
NHS England has announced that around seven million people, including those aged 75 and over, people who are immunosuppressed and health and care workers will be
able to book an appointment for their Covid-19 booster vaccinations online or by calling 119.
Eligible staff are encouraged to book an appointment for a booster dose as soon as possible, provided it has been at least three months since their last dose of the
vaccine.
"For other eligible patients (not health and care workers), invitations are being sent out and will be landing on their doormats from Wednesday 7th September
inviting people to book their appointment for the following week without delay. The NHS will contact people when it is their turn to book in for the vaccine -
there will be no need for patients to contact the NHS," said PSNC.
A fourth dose of Covid-19 vaccine is not needed at present, as latest data shows first booster provides high levels of protection against Omicron variant among older adults, says the Joint Committee on Vaccination and Immunisation (JCVI).
After analysing latest data from the UK Health Security Agency (UKHSA), JCVI said: "There is no immediate need to introduce a second booster dose, or fourth jab,
to the most vulnerable".
Data from UKSHA revealed that single booster dose provides around 90 per cent protection against hospitalisation to those aged 65 and over, even after three months of jab.
However, protection against mild symptomatic infection is short-lived and drops to around 30 per cent by about three months.
The study, which looked at booster doses in those aged over 65, showed that with two vaccine doses, protection against the infection drops to around 70 per cent after three months and to 50 per cent after six months.
The Department of Health and Social Care (DHSC) is encouraging people to come forward for their first and/ or second dose of the Covid vaccine before the free
offer ends on Friday (30 June).
The NHS's world-leading vaccination programme has so far delivered over 146 million Covid jabs.
Building on the success of autumn and spring booster programmes, a seasonal, targeted vaccination offer will remain open for those most at risk, in line with advice
from the Joint Committee on Vaccination and Immunisation (JCVI).
Health Minister Maria Caulfield said: "As we live with Covid without restrictions on our freedoms, it is right that we move towards a more targeted vaccination
offer that prioritises those most at risk, so we can focus our efforts on cutting waiting lists for NHS treatment - one of the Prime Minister's top five priorities.
As the offer for any adult to get a Covid vaccine comes to an end on 30 June, I would urge those who have not yet come forward to choose to have the first and second
Covid vaccine. It takes minutes to get your jab and thousands of sites are open across England."
This year's spring booster programme continues to gather pace, with over two million eligible people receiving their vital top-up dose.
Recent uptake of COVID-19 vaccine booster doses in Europe has been "rather disappointing," an official said on Thursday (November 24), amid concerns that
protection against severe cases of the disease could weaken during the winter.
The European average rate of re-vaccination, or receiving booster doses, was only 29 per cent in the groups of people considered to be at highest risk, such as
the elderly and immunocompromised.
"It is of concern that those most at risk of hospitalisation or severe COVID are not adequately protected," the European Medicines Agency's head of health threats
and vaccines strategy, Marco Cavaleri, told a news briefing.
Though there have not been major increases in COVID-19 case rates in recent weeks, Cavaleri said that could change during the colder winter months.
Britain's Covid booster campaign is set to kick off this September, after the country became the first in the world to approve an Omicron-adapted shot.
Around 26 million people in Britain are estimated to be eligible for an autumn Covid-19 booster, having had at least two Covid vaccine doses already, a UK Health
Security Agency (UKHSA) spokesperson said.
The preference is to deploy what is known as a "bivalent vaccine" that targets both the original virus and the Omicron variant through the autumn campaign, but that
will depend on the health regulator (MHRA) approving such shots and the state of vaccine supplies.
The UK's Joint Committee on Vaccination and Immunisation (JCVI) has advised boosters should be given to over-50s, individuals in clinical risk groups, frontline
workers and care-home staff ahead of the winter, when respiratory viruses are typically at their peak.
On Monday (August 15), the MHRA gave Moderna's bivalent shot conditional approval.
The endorsement of the vaccine is based on data that showed it produced a marginally better immune response against some Omicron variants, versus the original novel
coronavirus - although whether that translates into stronger protection against serious disease is unclear.
French drugmaker Sanofi said on Monday (June 13) an upgraded version of the Covid-19 vaccine candidate it is developing with GSK showed potential in two
trials to protect against the virus's main variants of concern, including the Omicron BA.1 and BA.2 strains, when used as a booster shot.
While the two companies' first experimental Covid shot is undergoing review by the European Medicines Agency, Sanofi and GSK have continued work on a vaccine that
is moulded on the now-supplanted Beta variant, hoping still that it will confer broad protection against future viral mutations.
Sanofi said this new vaccine candidate was shown to significantly boost antibody levels against a number of variants of concern, when given to trial participants
who had an initial course of mRNA vaccines, a type made by BioNTech-Pfizer and Moderna.
In a separate trial conducted by a French hospitals network, Sanofi's Beta-adapted booster shot triggered a higher immune response than Sanofi's first-generation
shot or Pfizer-BioNTech's established vaccine in previously vaccinated volunteers.
Health authorities in India have said that Biological E's Covid-19 vaccine Corbevax can be administered as a booster dose in people who have taken the
country's other two main shots, Covaxin and AstraZeneca's Covishield, from Friday (Aug 12).
Corbevax will be available to over 18s as precautionary booster six months after a second dose, the health ministry said in an August 8 letter to state authorities.
Covishield is produced for the Indian market by the Serum Institute of India under licence from AstraZeneca, while Bharat Biotech makes Covaxin.
India has so far administered more than 2 billion Covid vaccine shots, including 113 million boosters, all of which have so far been of the same vaccine as the
recipient's first two doses. The government says about 89 per cent of Indians above the age of 12 have had two doses.
As part of efforts to streamline spending and enhance resource allocation within the healthcare system, the NHS has chosen to cease providing the free
vaccinations for all, which were initially introduced in 2020. Approximately 12 million British citizens will not have access to free flu vaccinations and
Covid-19 boosters during the upcoming winter, according to NHS.
Furthermore, the NHS plans to defer flu vaccine distribution to October, aiming to heighten protection for those aged 65 and older and other eligible groups in
the high-risk winter months. However, this has stirred panic among pharmacies, given their advanced planning based on the initial start date of September 1 for
vaccinations.
On Tuesday (Aug. 8), the Joint Committee on Vaccination and Immunisation (JCVI) released NHS guidelines indicating that Covid-19 booster shots, starting from autumn,
will not be provided to individuals aged 50 to 64 who are in otherwise good health. Similar guidance had already been released for flu, rendering 12 million
middle-aged Britons ineligible for free jabs, JCVI said.
Prior to the pandemic, influenza vaccinations were available to healthy adults aged over 65, alongside children and younger adults with medical conditions. Amidst
the pandemic, the distribution of flu vaccinations was expanded to include individuals aged 50 to 64, in alignment with the criteria for Covid-19 boosters.
NHS England has agreed to offer an additional payment of £2.50 per jab if pharmacies would be willing to extend the duration of their COVID-19 vaccination
contract until 31st August 2024.
Pharmacies currently providing the autumn vaccination are asked to let their local commissioner know, by 22nd February 2024, if they can provide cover for a
potential Spring booster programme, if the Joint Committee on Vaccination and Immunisation (JCVI) advises in their guidance expected to be published soon.
NHS figures showed that more than 3,500 community pharmacies signed the contract to deliver COVID-19 vaccinations between 1 September 2023 and 31 March 2024, as
part of the autumn booster programme.
The health service is hoping that most of these pharmacies will be able to continue to support the Spring campaign, which will run from 1 April 2024 to 31st
August 2024, to help protect the nation's most vulnerable populations.
For the Spring campaign only, pharmacies would be offered an extra £2.50 per jab in addition to the existing item of service fee of £7.54, NHS England said.
For the first time, Covid-19 vaccines will be available for purchase from pharmacies in Britain from April 1.
As revealed by The Times, Boots is set to launch a private vaccination service next week to ensure that people "remain ready to respond to this constantly
evolving and unpredictable virus."
Under the NHS national immunization programme (NIP), Covid booster vaccines are only offered to those at high risk, including over-65s or patients with weakened
immune systems.
From April 1, anyone aged 12 or over can get the Pfizer-BioNTech Covid-19 vaccine at 50 Boots stores for £98.95.
While it's highly unlikely for healthier young adults to experience severe Covid-19, getting the single-dose vaccine can protect them from discomforting symptoms
like coughs and sore throats.
A spokesperson for Boots told the publication that their private service is the extension of their existing delivery of Covid-19 vaccinations for the NHS.
Prime minister Boris Johnson has said he is cautious about rising cases of Covid in Europe, warning of gathering "storm clouds" of a new wave of coronavirus infections.
He made the statement during a visit today (November 12) to a vaccination centre at a community pharmacy in Sidcup, London while encouraging people to come forward
for Covid-19 boosters.
The UK has had much higher rates of Covid-19 than the rest of Western Europe since the summer when Johnson scrapped coronavirus restrictions in England.
However, rates in Britain are now coming down just as they are rising sharply in countries such as Germany, Austria and the Netherlands. Parts of Eastern Europe
have also seen a sharp rise in cases.
Deviating from the initial schedule to kick off the flu and Covid-19 vaccination campaigns in October, the NHS England has announced that the autumn
vaccination drive will commence sooner than expected in England, starting on September 11. This decision was taken as a precaution in response to a new Covid-19
variant.
The precautionary measure is being taken as the Department of Health and Social Care and the UK Health Security Agency examined the variant BA.2.86, which was first
detected in the UK on Friday, August 18, 2023, the NHSE said on Aug. 30.
While NHS England had previously announced that vaccinations for both NHS programmes would begin on October 2 for residents of older adult care homes, appointments
for other eligible groups were scheduled for the following week, starting on October 7. This decision prompted community pharmacy leaders to denounce the delayed
start of the flu service as 'unacceptable'.
Prime minister Boris Johnson announced on Wednesday (January 19) that restrictions re-imposed in England last month would be lifted by from next Thursday (January 27).
In the latest development, the government has decided to end the guidance on working from home, asking employers to make adequate arrangements to return safely to work.
From the start of next Thursday, mandatory certification based on vaccines and tests will end, however, organisations can still choose to use the NHS Covid Pass voluntarily.
Besides, the legal mandate to wear face masks will go away from next week.
Making a statement to the House of Commons on Covid-19, he said that infection levels are falling in England mainly because of the country's "extraordinary booster campaign".
He noted more than 36 million Covid-19 booster jabs had been delivered, with over 90 percent of over-60s now given a third dose.
"Our scientists believe it is likely that the Omicron wave has now peaked nationally," Johnson added, while cautioning "the pandemic is not over".
"I encourage everyone across the country to continue with all the cautious behaviours that we know help to keep each everybody safe."