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British drugmaker AstraZeneca says it's confident that its new version of COVID-19 antibody treatment could protect immunocompromised patients against all known virus variants. Laboratory studies show the antibody, called AZD3152, neutralises all known variants of COVID-19 and AstraZeneca has support from regulators to make the treatment available by the end of this year, the company's vaccines head Iskra Reic said on Tuesday (April 18). AstraZeneca plans, pending more positive data and regulatory approval, to make the antibody available by the end of 2023. These types of therapies are most needed for people with compromised immune systems, either because of underlying conditions or because they are undergoing immune suppressing treatments. They account for nearly 2% of the global population. AstraZeneca's AZD3152, it new COVID-19 antibody, was acquired through a $157 million deal last year with British biotech start-up RQ Bio. The British drugmaker will likely make future investments like its current partnerships with RQ Bio but did not have any deals to announce, said Reic, a long-time AstraZeneca executive who has led the company's vaccines and immune therapies unit since it was formed in late 2021, during the pandemic.

The UK government's community diagnostic centre programme, which was first launch in July 2021, is helping cut waiting lists, and speed up diagnoses and treatments for NHS patients. As of November 2023, a total of 6.1 million vital checks have been carried out at community diagnostic centres (CDCs) across England, according to a joint statement released by the Department of Health and Social Care (DHSC) and NHS England. Under the £2.3 billion programme, 141 CDCs have been opened across the country in a variety of settings including shopping centres, university campuses and football stadiums, offering patients a wide range of diagnostic tests closer to home. The government has set a target to open 160 CDCs by March 2025, with many expected to open ahead of schedule.

The recent industrial action by junior doctors and hospital dental trainees, which is considered the longest strike in NHS history, caused a significant impact on the NHS services. Data published by NHS England showed that 113,779 inpatient and outpatient appointments were rescheduled due to the strike, which began on Wednesday 3 January at 7.00am and finished at 7.00am on Tuesday 9 January. Junior doctors make up around half of all doctors in the health service, but 25,446 staff remained absent from work at the peak of the last week's latest action. The ongoing dispute between junior doctors and government over the 2022/23 pay award has disrupted more than one million hospital appointments so far. The junior doctors' strike in December 2023 impacted 86,329 hospital appointments, and their previous action in October saw over 86,000 appointments cancelled.

In a recent announcement the Medicines and Healthcare products Regulatory Agency (MHRA) unveiled its strategic approach to artificial intelligence (AI), as it sets out to embrace the transformative potential of AI in healthcare regulation. Building upon the Government's white paper 'A pro-innovation approach to AI regulation', released in 2023, the MHRA outlined five key strategic principles guiding its adoption of AI. These principles encompass safety, security, and robustness; appropriate transparency and explainability; fairness, accountability, and governance; and contestability and redress. A science-led organization, the MHRA was tasked with providing an independent view of its approach to AI in medicine and science, aligning with a government white paper. Recognising its role in UK's goal to be a science and tech leader by 2030, MHRA is tasked to evaluate AI's opportunities and risks across regulatory, public service, and evidence-based decision-making area.

In a remarkable turn of events, the NHS App has emerged as a financial saviour for the National Health Service, slashing costs by over £1 million in the last year alone. The revelation comes as a testament to the app's growing significance in streamlining patient communication and service delivery. Throughout the fiscal year 2023/24, a staggering 22.5 million messages traversed the NHS App, a feat previously reliant on traditional methods like text messages or letters. This monumental shift not only signifies a boon for efficiency but also heralds substantial savings, with each text message costing an average of 5p. Drastically reducing these expenses has amounted to a commendable £1.1 million in savings, marking a pivotal milestone in NHS expenditure management.

The results of a national NHS staff survey, published recently, revealed that frontline healthcare workers are facing record levels of discrimination at work, with 58,000 respondents reporting that they experienced "unacceptable" levels of unwanted sexual behaviour from the public last year. Concerningly, 8.67 per cent of 675,140 NHS workers who responded to the poll said they suffered sexual harassment from patients, patients' relatives, or other members of the public in 2023. Particularly, ambulance staff were affected, with nearly 25 per cent of staff reporting unwanted sexual behaviour from the public last year. According to the survey findings, 3.84 per cent of staff also encountered unwanted sexual behaviour from their colleagues. Dr Navina Evans, Chief Workforce, Training and Education Officer, described the survey results as "very distressing" and said that "such conduct should not be tolerated in the NHS." On the positive side, more NHS workers reported being happier at work and experiencing less burnout than before. Over half of the participants stated they look forward to coming to work, the highest number since 2020, as per the NHS. Dr Evans attributed this improvement to initiatives such as flexible working hours, clinical support squads to help menopausal women at work, and human resources stay advocates.

More than 300 fully-funded training places will be open to pharmacists and pharmacy technicians working in adult critical care units in England this year. NHS England has awarded a contract to the UK Clinical Pharmacy Association (UKCPA) to deliver 200 funded continuing professional development places for pharmacists and pharmacy technicians from April 2024. Another school of pharmacy, the name of which has not been announced yet, will deliver 100 funded places on a pharmacist adult critical care pathway. There are already 15 funded places on an adult critical care training pathway for pharmacy technicians provided by the University of Bradford. Reacting to evidence indicating workforce concerns in critical care, NHS England invited bids from training providers for delivering the training in November 2023.

The UK Health Security Agency (UKHSA) has warned that there has been a continued increase in cases of whooping cough (pertussis) across England since the start of this year. According to new data published by the agency on Thursday (7 March), 553 new cases of whooping cough were confirmed in January alone, compared with 858 cases for the whole of last year (2023). The country is witnessing a surge in whooping cough cases after a prolonged period of low case numbers, attributed to restrictions and reduced social interaction during the COVID-19 pandemic. England recorded the highest number of whooping cough cases in 2016, recording 5,949 cases. As the ongoing rise coincides with a steady decline in the vaccination rates among pregnant women and children, UKHSA has strongly encouraged mums-to-be to get the maternal pertussis vaccine so that their young baby is protected against this serious disease.

Responding to a new National Audit Office (NAO) report that indicated that NHS England's Long Term Workforce Plan (LTWP) needs improvements, the Royal College of General Practitioners (RCGP) has expressed concerns that the plan may not adequately address the needs of GPs. Published in June 2023, the workforce plan estimated that the NHS's health workforce will need to grow from 1.4m full-time equivalent (FTE) staff in 2021-22 to between 2.3m and 2.4m FTE workers in 2036-37, an increase of 65 per cent to 72 per cent. However, the NAO report highlighted that the workforce modelling has significant weaknesses, including a complex design; manual adjustments; optimistic future assumptions and limited public communication of their uncertainty; and modelling outputs that could not be fully replicated. To improve the modelling, the report recommended exploring the uncertainty of these assumptions and considering potential outcomes if they do not materialize as expected. Additionally, it suggested including full integration of the different parts of the modelling pipeline to minimise manual adjustments.

NHS England has launched a cloud-based platform that links recently-retired consultants, who still hold a licence to practice, with secondary care providers who need additional help with their waiting lists. It has been developed to make it easier and more flexible for retired doctors to return to the health service as part of the Long Term Workforce Plan. NHS chief executive Amanda Pritchard in June 2023 announced the NHS Emeritus pilot scheme, which is expected to help reduce long waits for elective care. Initially, the scheme will run for a year across England, and if successful, it may be expanded to cover other work areas. Health Minister Andrew Stephenson commented: "Returning consultants will bring invaluable experience and knowledge, and the new digital platform will match highly-skilled consultants with the NHS trusts that require their expertise, providing high quality care and alleviating pressures on high demand areas.

The UK Health Security Agency's (UKHSA) Chief Executive, Professor Dame Jenny Harries has expressed concern that measles outbreak could spread to other towns and cities unless urgent action is taken to increase Measles, Mumps and Rubella (MMR) vaccination uptake in areas at greatest risk. The virus can spread very easily among those who are unvaccinated, especially in nurseries and schools, she said on Friday (19 January) during a visit to irmingham to review the ongoing work to contain the spread of the disease. A rapid rise in cases has been seen in the West Midlands since 1 October 2023, with 216 confirmed cases and 103 probable cases recorded till 18 January. The majority of the cases (around 80 per cent) were reported from Birmingham, with about 10 per cent in Coventry, mostly affecting children aged under 10 years. Dame Jenny is calling on all local areas to increase MMR vaccine uptake rates in communities across the country.

In a move to make healthcare more accessible, the Department of Health and Social Care (DHSC) has announced plans to empower pharmacy technicians, dental therapists, and hygienists with enhanced authority following two public consultations run by the government in 2023. Revealed by Primary Care Minister Andrea Leadsom on Thursday 28th March, this strategic decision promises to usher in "a faster, simpler, and fairer access to primary care" by granting pharmacy professionals "the ability to both supply and administer medications". Based on the public consultations that garnered widespread support, with 97% backing the empowerment of dental hygienists and therapists and 84% favouring similar rights for pharmacy technicians, the new reform is aimed to cut through bureaucratic red tape and bolster efficiency in patient care. Dental hygienists and therapists, under the proposed change, will be empowered to administer select medications, including pain relief and fluoride, without the need for dentist approval.

Pharmacy Business and Haleon jointly hosted a practical Pain Management webinar on 5 December 2023. The webinar was specially designed to empower community pharmacies with effective strategies for understanding, managing, and reducing pain in their patients' daily life. Pharmacist Faheem Ahmend, director at Health Clinic & MEDLRN, and Linda Perry, account relationship manager OTC at Haleon, engaged in an insightful and informative conversation, highlighting real issues in the pharmacy setting and practical solutions to support community pharmacists.

In 2023, almost 14,000 people in England are estimated to have died due to excessive waits in emergency departments, averaging more than 260 deaths per week, according to new figures from the Royal College of Emergency Medicine (RCEM). The RCEM estimate is based on a large study of NHS patients published in the Emergency Medicine Journal in 2021, which found one excess death for every 72 patients who spent eight to 12 hours in an A&E department. Following a Freedom of Information audit of NHS trusts, the college has found that 65 per cent of people waiting 12 hours or more in A&E were patients waiting for a hospital bed. NHS data for England revealed that over 1.5 million patients waited 12 hours or more in major emergency departments last year. Based on the RCEM calculation, this indicates that over a million of those patients were waiting for a bed.

The outbreak of Burkholderia cepacia complex (Bcc) in the UK, which is associated with contaminated eye gels imported from India, has led to the death of one person, and many others falling ill, according to a government report. Bcc is a group of antibiotic-resistant bacteria that are widely found within the environment. Although it rarely causes infection, it can result in severe ones in individuals with compromised immune systems and those living with cystic fibrosis, the UK Health Security Agency (UKHSA) said. Between January 2023 and February 2024, there were 52 confirmed and six probable cases across the UK linked to the bacteria outbreak, as revealed in the Health Protection Report published by UKHSA. Forty-one of these cases were hospital inpatients, 38 of which were in critical-care settings. Twenty-five cases were considered to have "clinically significant infections attributable to Bcc", out of which 11 had eye infections, nine had respiratory infections and four had bacteremia (bacteria entering the bloodstream). Two individuals with cystic fibrosis (CF) were infected, and while one was treated, the other died, with the report indicating Bcc infection to have "contributed to the death."

Online vape store GoSmokeFree analysed data from NHS Stop Smoking Service in England from April to September 2023 to determine the number of individuals in each of the nine UK regions who reported successfully quitting smoking after setting a quit date. The findings showed that the South East has the highest number of successful quitters, with 1,226 smokers per 100,000 reporting to have given it up. The Isle of Wight is the most successful area to quit smoking in the South East with 3,124 people quitting per 100,000 smokers. Of the 4,294 individuals who set a quit date in this region, 803 admitted to not being able to achieve their target. A spokesperson from the online retailer noted that overcoming nicotine withdrawals and mental challenges can be exceptionally difficult when attempting to quit smoking.

The severity of the ADHD medication shortage in the UK has been exposed as former Hollywood extra Lee Cato revealed that he was forced to quit his job but hasn't been able to access his medicine. A resident of Berkhamsted, Hertfordshire, Lee had worked as a film extra in big movies like 'Thor' and 'Edge of Tomorrow'. The 48-year-old told Mirror that he has been taking Concerta for years to manage ADHD symptoms, but he hasn't been able to get the drug or any alternatives for over a month. He said that he first experienced shortages of the medicine in December 2023 but was initially able to take Delmosart, which he took to maintain focus despite experiencing its side effects such as headaches, nausea, tooth erosion, and a dry mouth. But now, he can't get access to any of these ADHD drugs as "they're completely out-of-stock and it's been over a month now." His chemist also tried to get hold of his medication but failed.

Adding to the growing evidence of global medicine shortages, a new study has revealed that the European generic medicines market is "not in shape" to help Europe meet its public health priorities. In the past decade, the rate of generic medicines withdrawals has risen by 12 per cent, while there has been a three per cent decrease in the launch of generic products, as per Teva Pharmaceuticals' recent analysis of IQVIA data. Within the mental therapeutic area, seven per cent of generic products disappeared between 2013 and 2023, while there was a seven per cent decrease in the availability of generic cancer medicines in just six years (2017-2022). These medicines were listed on the Union List of Critical Medicines to help avoid potential shortages, as the European Commission (EC) said this could cause "significant harm to patients and pose important challenges to health systems." While mature generic products constitute the majority of the List, they remain susceptible to withdrawals, despite containing products crucial for safeguarding Europe's public health, the Teva analysis report noted. Since 2013, the number of generic products for the treatment of schizophrenia and bipolar disorder has declined by 25 per cent, with Hungary and Bulgaria experiencing the biggest loss at 83 per cent and 58 per cent respectively.

Campaigners have submitted an open letter to the Department of Health and Social Care (DHSC), urging the Minister for Primary Care and Public Health to freeze prescription charges to keep people with long-term conditions alive and well. The campaign is led by the Prescription Charges Coalition, which represents over 50 organisations, including Royal Pharmaceutical Society (RPS) and Pharmacists' Defence Association (PDA). Currently, the prescription charge is £9.65 per item, and campaigners have asked the government to freeze it for 2024 and 2025 as people living with long-term health conditions in England are "being forced to choose between heating, eating, and taking their vital medication on a daily basis." In 2023, a study conducted by the Prescription Charges Coalition revealed that almost 10 per cent of survey participants had skipped medication in the previous year due to the cost of prescriptions. This led to increased physical and mental health problems, as well as impacted the time they took off work. Laura Cockram, Chair of the Prescription Charges Coalition and Head of Campaigns at Parkinson's UK, expressed deep concern that a further rise in the charge this year will lead to people skipping or not taking the full dose of their medication, which will affect their health and put more pressure on the already under pressure NHS.

Community Pharmacy England (CPE) has reminded community pharmacy owners that the deadline to complete the 2023/24 Data Security and Protection Toolkit to make their information governance (IG) declaration is 30 June 2024. Sometimes referred to as the "NHS IG toolkit", the DSPT is a set of security requirements that companies are required to fulfill to supply goods and services to the health service to ensure the safety and protection of sensitive patient information. To help community pharmacy contractors complete the mandatory questions within the Toolkit, CPE on Monday (12 February) published new guidance, which also contains references to other useful materials. CPE is working with the NHS DSPTK team to keep the workload associated with Toolkit completion manageable whilst ensuring that appropriate data security protections are maintained. Pharmacy owners with three or more pharmacies can complete a single submission for all their premises through the NHS Parent Organisation Code (POC) headquarters (HQ) batch submission feature.