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Johnson & Johnson said on Wednesday (January 18) that it was pulling the plug on a late-stage global trial of an HIV vaccine after the shot was found ineffective at preventing infections. The failure of the trial marks yet another setback in the search for a vaccine against a virus known to mutate rapidly and find unique ways to evade the immune system, and comes more than a year after another of J&J's HIV vaccine failed a study. "It's not the outcome we had hoped for, unfortunately," said a spokesperson for the National Institute of Allergy and Infectious Diseases, a J&J partner in the trial. "The development of a safe and effective HIV vaccine has been a considerable scientific challenge, but we will learn from this study and continue forward." The trial involved administering two different types of a shot, which uses a cold-causing virus to deliver the genetic code of HIV, spread over four vaccination visits in a year. J&J used similar technology for its COVID-19 vaccine. The study, which began in 2019, was conducted at over 50 sites and included about 3,900 gay men and transgender people - groups that are considered vulnerable to the infection.

Panadol launched a new purpose-led brand idea as part of a multi-channel campaign across Great Britain and Ireland. With nine out of 10 people suffering "everyday pain" and 65% of people saying they can't be happy when they are in pain[1], globally, the campaign reiterates the brand's commitment to holistic pain management by focusing on the acute pain recovery journey. Rooted in deep consumer understanding, the campaign idea celebrates that never-talked-about moment of realisation when you start to feel the release from pain. The new brand idea will bring to life the emotional transformation that those suffering from acute pain undergo, emphasising the role that Panadol can play in alleviating their pain. The Panadol campaign follows a period of strong sales growth for the brand, outperforming the category's own expansion by more than double[2]. This has been driven by shoppers who are searching for fast and effective pain relief products, such as Panadol's hero variants, including Panadol Extra Advance Tablets (paracetamol, caffeine), which has seen its growth almost doubled[3], as well as Panadol Advance Tablets (paracetamol) and Panadol Extra Advance Tablets. Monica Michalopoulou, GBI Marketing Director, said: "After two years of pandemic restrictions, now more than ever, people want to get back to their normal lives and to the people they love. But with pain preventing many of us from connecting with those we love or from doing the things we enjoy the most, we want to help consumers by understanding their pain journey and reassuring them on the treatments we can provide. This "Release" moment is so important for pain sufferers, and we hope our new brand campaign can shine a light on the role that Panadol can play in pain relief".

The General Pharmaceutical Council (GPhC) Fitness to Practise Committee has removed a pharmacy technician from Register after been found guilty of possessing 'indecent photographs of a child'. Graeme Arthur, a pharmacy technician first registered with GPhC on 1 September 2019, under the registration number 5039154, was found guilty at Peterlee Magistrate's Court in August 2022. He received an 18-month Community Order, and is subject to a Sexual Harm Prevention Order for 5 years, He was also ordered to undertake a period of rehabilitation activity for 40 days. In the remote video linking hearing held on 2 - 3 May, the Fitness to Practise Committee found Arthur's fitness to practise to be currently impaired on grounds of protection of the public and in the wider public interest of declaring and upholding the Standards of the profession and maintaining public confidence in the reputation of the profession. The committee considers this to be a serious conviction for an offence which has included possession of the most serious category of images of sexual abuse of children. It said: "Although Mr Arthur had no direct contact with the children concerned, the nature of the abuse is that it thrives on the demand from those who search for and view the images online. As such, children come to actual harm indirectly through the activity of someone viewing and possession of images of sexual abuse."

BioNTech and Pfizer are to start tests on humans of next-generation vaccines that protect against a wide variety of coronaviruses in the second half of the year. Their experimental work on shots that go beyond the current approach include T-cell-enhancing shots, designed to primarily protect against severe disease if the virus becomes more dangerous, and pan-coronavirus shots that protect against the broader family of viruses and its mutations. In presentation slides posted on BioNTech's website for its investor day, the German biotech firm said its aim was to "provide durable variant protection". The two companies are currently discussing with regulators enhanced versions of their established shot to better protect against the Omicron variant and its sublineages. The virus' persistent mutation into new variants that more easily evade vaccine protection, as well as waning human immune memory, have added urgency to the search by companies, governments and health bodies for more reliable tools of protection. As part of a push to further boost its infectious disease business, BioNTech said it was independently working on precision antibiotics that kill superbugs that have grown resistant to currently available anti-infectives.

Mental health problems can be incredibly isolating and debilitating. It can be difficult to know how to get your life back on track when you are struggling with mental health issues. In this blog post, we will discuss some strategies for overcoming mental health problems and getting your life back on track! 1. SEEK PROFESSIONAL HELP: Mental health problems can be complex and difficult to manage on your own. If you are struggling with mental health issues, it is important to seek professional help. A therapist can help you understand and manage your symptoms, develop healthy coping mechanisms, and work through any underlying issues that may be contributing to your mental health problems. If you are not sure where to start, you can ask your primary care doctor for a referral to a mental health professional. You can also go to a treatment center where their clinical team will help you with your mental health. This way you ensure that you're getting the help that you need and not just from a family member or friend. You can also search for therapists in your area online or by calling your insurance company. There is no shame in seeking help for mental health problems. In fact, seeking professional help is one of the most important things you can do for your mental health. 2. DEVELOP A SUPPORT SYSTEM: When you are struggling with mental health issues, it is important to have a supportive network of people on who you can rely. This may include family members, friends, therapists, or a support group for people with similar experiences. Having people to talk to who understand what you are going through can be incredibly helpful. These people can provide support, advice, and practical assistance when you need it. Having a strong support system can make a big difference in your ability to cope with mental health problems.

The Criminal Enforcement Unit (CEU) of the Medicines and Healthcare products Regulatory Agency (MHRA) seized a large quantity of suspected illegally traded medicines, including powerful prescription-only medicines, during raids conducted at two residential and two business premises across North Manchester. Officers from the MHRA and Greater Manchester Police carried out searches across two residential addresses in Oldham and Cheetham in the early hours of Wednesday (29 November), and arrested a man in his 20s on "suspicion of conspiracy to supply controlled drugs, breaches of the Human Medicines Regulations 2012 and money laundering." They also seized thousands of illegal medicines from two business addresses in Bury and Miles Platting, including powerful opioid painkillers and antidepressants, as well as unlicensed versions of erectile dysfunction drugs.

The Manchester Crown Court on Friday (9 December) sentenced three men, Cleave Lewis (35) and brothers, Denis Sutherland (58) and David Sutherland (59), to a total of three years in jail after they pleaded guilty to the illegal sale and supply online of prescription-only medicines and controlled Class B and Class C drugs, worth more than £1.5m. They were found in possession of nearly 1.3m tablets of prescription-only drugs, including powerful sleeping pills, painkillers and anti-anxiety meds, when officers from the Medicines and Healthcare products Regulatory Agency (MHRA) and Greater Manchester Police searched their residential homes and business premises in October 2017. Following investigations by the agency, they also pleaded guilty to illegally making these medicines available online on three different websites for the public to purchase without prescriptions. The officials also recovered controlled medicines, over half a million (525,737) erectile dysfunction, slimming and herbal tablets, with an estimated value of approximately £500k, from them.

The National Pharmacy Association (NPA) has announced the retirement of its Chief Executive, Mark Lyonette. Mark will retire in 2024. The association has announced his retirement well in advance so that the Board can start work with a leading recruitment agency to search for the new Chief Executive. "The Board is keen to build on the strong foundations established and ensure there is a seamless transition and minimum disruption to the business once the new Chief Executive is in post," said the association. Mark said: "After five years at the NPA and 40 years working for and leading national membership organisations, I am looking forward to living a different life. "I am pleased that in the time that I have been with the NPA we have grown both the membership and customer base and created a profitable, stable membership organisation. "Alongside our NPA Insurance company, the association is well set to help members face the future. "Meanwhile there is much to do to ensure that 2023 is another good year in terms of the NPA delivering consistently for members. The process of changing Chief Executive won't deflect us from our vital work."

Well Pharmacy has announced the acquisition of Lexon UK Holdings and Asurex Limited, a family-owned pharmaceutical wholesaler with five depots in Redditch, Leeds, Durham, East Kilbride and Dublin and a network of community pharmacies across the Midlands, Northwest, and Northeast of England. Lexon, is a family-owned business which has been in operation for over 25 years, running primarily as a pharmaceutical wholesaler for 3,000 retail pharmacy customers across the UK and Ireland. The business also operates 42 community pharmacies - currently trading as Knights Pharmacy - and is also a specialist developer and manufacturer of generic pharmaceuticals and is a data and solutions provider to pharmacy. The acquisition will be notified to the Competition and Markets Authority (CMA). Both parties have proactively engaged with the CMA in pre-notification discussions and look forward to continuing to do so productively during the CMA review period. Haider Choudrey, CFO of Bestway Group which own Well Pharmacy, said: "Through this acquisition we seek to augment our growth momentum and bring in even greater benefits to both community pharmacies and patients. Well Pharmacy had been searching for a target to expand its footprint and complement its growth trajectory and we are confident that Lexon fits this criterion."

Patients want to be active partners in their healthcare decisions - and eye care is no exception. Patient education is vital for understanding diagnoses, treatment options, and the importance of preventative care. When patients understand what's happening with their health, they're far more likely to follow their treatment plan and see good results. Here's a deeper look at why patient education matters. Patient-Centered Care: The Key to Success The Institute of Medicine emphasizes the importance of patient-centered care. This means involving patients in decision-making and providing them with the necessary education for informed choices. This approach is even more crucial in eye care, where conditions can lead to irreversible blindness. The Need for Patient Education Research shows that many patients crave educational materials from their eye care providers, but many don't receive them. This leaves patients searching for information on their own, potentially turning to unreliable sources. Clear, accessible patient education is vital in ensuring understanding and treatment adherence.For instance, patient education is crucial in preventing diseases like glaucoma. The more informed patients are, the more chances they will discover early signs of disease by taking OCT test for glaucoma.

A drug dealer who was operating as an "unlicensed chemist" and selling prescription drugs online has been jailed for six years, according to Essex Police. The convict, identified as 49-year-old Christopher Depp, aka David Jones, was supplying a range of drugs from his home to "vulnerable people" using the postal service, local police revealed on Friday (February 16). Police conducted a search operation at his address in Wood Street, Chelmsford, in July last year and found more than 50,000 pills and tablets of varying types, stashed in toolboxes and spaces around the property. To process the large-scale sale and shipping of controlled drugs across the UK, Depp had set up a room in his property as an office space. He promoted the sale of medications through various social media platforms and messaging applications, and accepted payment from his large customer base using "fraudulently obtained" bank accounts.

Walgreens Boots Alliance (WBA) has officially announced that Sebastian James, the Managing Director of Boots, will be stepping down from his role to pursue a new opportunity in the healthcare sector. James has given notice to leave the company and will remain with Boots until November. The UK pharmacy giant has already begun the search for a new Managing Director. James is set to take on the role of CEO at Veonet, a leading European chain of ophthalmology clinics. During his tenure as Managing Director since 2018, James played a pivotal role in transforming Boots into the UK's leading health and beauty retailer. He oversaw significant growth and innovation, achieving thirteen consecutive quarters of retail market share growth. Most recently, the company announced strong Q3 results in June with growth across all categories.

Being healthier and improving the success of treatment is much more (and perhaps much simpler) than applying the latest medical device technology, tablets, smartphones, video conferencing and social media. Everyone has alternatives. We are predisposed to select alternatives based on the similarity of our friends and colleagues to ourselves. It used to be called "Keeping up with the Joneses". A business developer searching for a solution to improve patient care, will be influenced by the fact that her friends and colleagues at work all have an iPhone, or an Android, or a Blackberry and sometimes all 3.

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