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Global pharmaceutical and biotechnology company AstraZeneca has signed an agreement with Scorpion Therapeutics to discover, develop and commercialize precision medicines against cancer proteins. The collaboration, announced today (January 13), will focus on a class of proteins called transcription factors, which can regulate important cellular processes including cell growth and survival. Many transcription factors have been identified earlier, but were considered 'undruggable' using conventional drug discovery approaches, the company said in a statement. Susan Galbraith, executive vice president, Oncology R&D, AstraZeneca, said: "Unlocking potentially transformative biology is pivotal for delivering the next wave of cancer treatments. "Scorpion's innovative platform is a strong strategic fit as we explore a range of new modalities across our broad drug discovery toolbox with promise to disrupt the activity of these highly-validated cancer targets."

If your loved one is suffering from anxiety, you'll likely be aware of how damaging the condition can be. Anxiety comes in many forms and can be triggered by an array of factors, but there are some simple steps to take if you want to improve the wellbeing of your family member - how can you best go about supporting a loved one with anxiety? What is anxiety? - Anxiety is mental state in which we feel highly worried, nervous, uneasy, or uncomfortable. While it's normal to feel anxious in certain situations and at notable points in our lives (this is linked to the 'fight or flight' instinct), it's important to address the problem if you feel that your anxiety is impacting your quality of life. What are the five major forms of anxiety? - The 5 most common forms of anxiety as diagnosed by medical professionals include generalised anxiety disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder and social phobia, also known as anxiety disorder. What causes anxiety problems? - Anxiety can be caused by a wide range of factors. We're more likely to become anxious when we're overworked, stressed, depressed, under financial pressure or physically or mentally unwell. It's also common to become anxious after traumatic events such as having to make medical negligence claim after sustaining a surgical based injury, losing a home or the death of a loved one.

The European Union's health regulator on Friday said it had recommended granting a conditional marketing authorisation for a gene therapy by Australian drugmaker CSL Ltd and partner uniQure N.V. , to treat haemophilia B, a rare bleeding disorder which is caused by genetic anomalies. About one in 40,000 people are affected by the inherited disorder, caused by a gene mutation that hampers the body's ability to make clotting protein factor IX. If approved, the treatment, branded Hemgenix, will be the first gene therapy in the European Union for the condition that is usually treated by regular injections of factor IX, the European Medicines Agency said. CSL had acquired exclusive global rights to Hemgenix in May last year from uniQure N.V.

It is a complete program designed to help you change up your nutrition and take up an exercising routine.

Acne Causes- A study on causes and aetiology of Acne with patho-physiology and risk-factors, meta-analysis of association between acne and hormonal causes.

Acne Causes- A study on causes and aetiology of Acne with patho-physiology and risk-factors, meta-analysis of association between acne and hormonal causes.

In recent NIH Alzeimer's cognitive decline prevention report, it has been observed that Cognitive training identified as protective factor, with highest evidence. Read more at sharpbrains.com

Women who have been detected early in the disease, they can usually be offered a curative treatment. The earlier the diagnosis is made, the greater the chance of cure. When it is found early, there is a 96% chance of healing. here is the complete Breast Cancer Symptoms, Risk Factors, Stages, Causes and Treatment

Sometimes even after eating regular meals you encounter the feeling of tiredness and headaches or pale skin and shortened breaths! All of the above factors collectively sum up for symptoms of Anemia.

Sometimes even after eating regular meals you encounter the feeling of tiredness and headaches or pale skin and shortened breaths! All of the above factors collectively sum up for symptoms of Anemia.

Whether you want to improve your overall health or want to become thin, it may not be easy to get rid of these excess weights. Apart from dieting, exercise and various dieting, other factors may affect weight loss and fat. Fortunately, you can take …

Whether you want to improve your overall health or want to become thin, it may not be easy to get rid of these excess weights. Apart from dieting, exercise and various dieting, other factors may affect weight loss and fat. Fortunately, you can take some steps to enhance the fat burning process.

Alzheimer's is a mental illness that mostly affects the elderly. It is characterized by dementia, cognitive impairment, and mood swings. The patient gradually fades into a state of perpetual darkness and lack of self-awareness. Here are some steps we can take to reduce our own risk.

Scientists are trying to find ways to prevent Alzheimer's before it comes knocking at your doorstep. Extensive research is taking place even as you read this. Everyone hopes to put together the answer before it becomes a global issue. Here are a few risk factors that you can and can't avoid:

There are a number of factors that you should consider when choosing your surgeon for augmentation mammoplasty.Dr.Core is specailist in breast augmentation in the area of Birmingham.Please feel free to contact with Dr.Core for breast augmentation.

The Karma Commode Chair Rainbow 5 is foldable, and can hence be carried around at will. It has a seat width of 17 inches and once folded, will accommodate in the smallest of corners. The height of this product can be adjusted as per that of the user. The Karma Commode Chair Rainbow 5 is a bright purple in colour with a silvery powder coating, and is smart to look at. This commode chair is very easy to clean and re-use, without compromising on the hygiene factor. Made using very durable steel, this chair is rust-free, and is hence virtually lifelong-assured. The size and dimensions of the chair ensure that it can be carried around at will. A Karma Rainbow 5 Commode, known in British English simply as a commode, is a type of chair used by someone who needs help going to the toilet due to illness, injury or disability. A Karma Rainbow 5 Commode has sometimes wheels to transport easily to the bathroom or shower. Most commode chairs have a removable pail and flip-back armrests.

Eyebrow hair loss is rare. However, this does not make it less disturbing for the people who experience it. There are many factors, which can contribute to the eyebrow hair loss. Over-plucking, medication, eczema, alopecia areata, and lupus are some common triggers of eyebrow hair loss

If travel by wheelchair or travel by scooter, make sure your wheelchair or scooter is in good working order before leave house. If chair has not been serviced recently, send it to a repair shop for a general check over. This extra effort can save the heartache of suffering a breakdown overseas; save the time wasted trying to locate a repair shop and save the time wasted waiting for the repair. Transport considerations should be factored into the initial phase of the wheelchair and seating assessment process. Manufacturers of Soma SM 150.3 wheelchairs and seating systems should make information relating to the safe transportation of their products readily available and easy to understand.

Asthma has been major risk factors for the people who are facing the problem of erectile dysfunction. This report has been generated according to market theory.

People want to know whether the Human Growth Hormone (HGH) can help them in growing taller, or not. The fact is that increase in the rate of your growth occurs only during the phase when you are a child and growing. HGH is manufactured by the pituitary gland in the brain and is responsible for the development and growth of human body. However, the pituitary gland does not produce HGH at its peak level all the time. Many factors such as abnormal pituitary gland, or imbalance of hormones can cause decreased levels of HGH in the body.

People enjoy healthy life due to number of factors in which both age and latitude come. Studies show that proper diet, physical activity, daily walk, pollution free environment, pure water, and heredity are the things that keep you healthy and young.

Release of growth hormones fluctuates during the young age due to many factors that include illness, diet, and exercise. This varied level also depends upon the life style of a person. A person engaged in activities that are more physical and take good diet has more amounts of growth hormone in the body

In this fast paced world human beings are living a luxurious life due to good science most of the works are done by machines, but this lack of physical activity has give way to many diseases and obesity that is considered to be the root cause of many health complications especially it is included into the major risk factors of breast cancer. Obesity is the result of unhealthy diet full of fats instead of healthy balanced diet and lack of physical activity so it must be kept at distance by adopting healthy life style.