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London pharmacist jailed for supplying Norwich drug addict - 0 views

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    A community pharmacist who supplied a drug addict with "under the counter drugs" has been jailed for 18 months. Dushyant Patel, 67, a London pharmacist with more than 40 years' experience, had supplied class C drugs to a drug user in Norwich for months in 2020. Police identified Patel as a suspect four months after the death of drug user, Alisha Siddiqi, whose body was found at a property in Colossus Way, Costessey, in August 2020. An initial post-mortem examination was inconclusive, but toxicology results later showed she died from an overdose of prescription medication. An analysis of her phone revealed that she had frequent communication with Patel between January and August 2020. Class C drugs sold without prescription There was also communication regarding transactions relating to the sale of prescription drugs including class C drugs, without a prescription, namely Zolpidem and Zopiclone. Patel was identified as a suspect and later charged with drugs offences. He was jailed at Norwich Crown Court in December after a trial in August when he was found guilty of two counts of being concerned in supplying a controlled drug between March and August 2020.
pharmacybiz

Home Testing Tips: Helpful Things And Sites You Should Know - 0 views

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    Drug testing is a crucial part of many people's lives. Whether you're applying for a job in the law enforcement field, military, or pharmacy industry, it can be difficult to find out what drugs are on your application. Luckily, there are new ways to test yourself at home to see if you have any traces of drugs inside of you. WHERE TO FIND DRUG TESTS There are a variety of at-home drug tests available on the market. Drug tests can be found at most pharmacies and online retailers, like Drug Test City. Some of these sites are free, while others charge a fee. Here are some tips to help you choose the right site for your needs: Make sure the site is reputable. There are many scam sites out there that will take your money and not deliver on their promises. Do some research to make sure the site you're considering is legitimate. Consider the cost. Some sites charge a fee for their services, while others are free. Decide what you're willing to spend before you start your search. Compare features. Not all drug testing sites are created equal. Some offer more comprehensive services than others. Take a look at what each site has to offer and choose the one that best meets your needs.
pharmacybiz

NHS marks 'Alpelisib' as 100th fast-tracked cancer drug - 0 views

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    The drug, alpelisib, which is the 100th cancer drug that has being fast-tracked to patients under the NHS Cancer Drugs Fund (CDF) will be used in combination with the hormone therapy, fulvestrant, to target the gene that causes fast-growing tumours. Up to 3,000 people a year with a certain type of secondary breast cancer will benefit from the treatment. The approach has contributed to people in England having access to nearly one third more cancer drugs compared to the European average. The drug which is manufactured by pharmaceutical company Novartis, is part of a growing number of precision treatments that target a tumour based on mutations in its DNA and that the NHS is rolling out. John Stewart, NHS National Director for Specialised Commissioning said, "In just over five years, more than 80,000 people have benefitted from earlier access to a range of cancer drugs, with people in England having access to nearly one third more cancer drugs compared to the European average, and this latest innovative new treatment will help up to 3,000 more to live a better quality of life.
pharmacybiz

Drug Storage : 6 Important Guidelines You Should Know About - 0 views

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    Proper drug storage is essential to ensure the safety of yourself, your family, and those around you. This is especially important if you are taking multiple medications and need to keep track of them all. Knowing how to store drugs correctly can help prevent misuse or accidental ingestion by children or pets. Here are six important guidelines about proper drug storage that everyone should follow: 1. KEEP ALL MEDICATIONS IN THEIR ORIGINAL, LABELED CONTAINERS: Using alternative storage containers can make it difficult to identify medications or keep track of expiration dates. Keeping medications in their original containers also prevents accidental misuse and helps ensure that the correct dosage is taken. In addition, it's important to store all medications out of reach of children and pets. Also, keep medications in a cool, dry place away from direct sunlight. For example, a medicine cabinet in the bathroom or kitchen is a good option. 2. DISPOSE OF EXPIRED MEDICATIONS: Expired medications can be less effective and even potentially harmful if taken, so it's important to regularly check expiration dates and get rid of any outdated medications. The best way to dispose of old drugs is to take them to a drug collection site. If no such sites are available, mix the medication with something like coffee grounds, put it in an opaque container, and then throw it away in your trash bin. Never flush expired medication down the toilet unless instructed by your pharmacist or healthcare provider! 3. STORE DRUGS IN A COOL, DRY PLACE: Extreme temperatures can cause medications to break down and become ineffective. To avoid this, keep all drugs away from direct sunlight, heat sources, and moisture. A medicine cabinet or drawer in the bathroom is an ideal spot for storing most drugs, but some require special storage conditions (more on that below). Different medications should also be separated from one another to avoid confusion and stored differently. For example, if a
pharmacybiz

New Medical Drug: Useful tools for developing - 0 views

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    Developing a new medical drug is no small feat. It requires extensive research, knowledge, expertise in the field, rigorous testing and iteration of prototypes, and strong organizational skills to manage these tasks. It is important to use the right tools to make this process as efficient and successful as possible. With the right tools available, you can streamline development, manage resources and personnel more effectively, and maximize the chances of success. Here are some tools that might be useful when developing a new medical drug: ANALYTICAL TESTING TOOLS One of the best tools available to medical drug developers is analytical testing tools. These allow you to quickly and accurately test various components of the new medication, ensuring that it meets all safety requirements and is ready for clinical trials. As highlighted by the team behind Venogen, various methods of analyzing, chemical identification, and purity certification can be used to ensure product quality. Be sure to select a tool that can accurately analyze the specific components of your new drug. When finding analytical testing tools for your drug development process, it is important to consider the tool's scalability. Consider the size and scope of your project and select a tool that can grow with you. You can also work with experts to find the right analytical testing tools for your development needs.
pharmacybiz

Addiction Drugs Treat Long Covid Symptoms - 0 views

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    The number of people suffering from addiction is at an all time high, with more people seeking treatment across the USA due to the fentanyl crisis, but new studies have shown that addiction drugs may not only be able to aid those suffering from the deadly disease, but also aid people suffering from long COVID. While there has long been research underway to find a cure for the likes of alcoholism and drug addiction, it turns out naltrexone, a drug used in the addiction treatment space, is helping people who have been suffering from headaches, seizures and fatigue as a result of long COVID. According to Dr. Paul Valbuena at The River Source, an Arizona drug rehab, naltrexone is typically used by rehab centers and prescribed to patients suffering from addiction to reduce cravings and the feeling of euphoria associated with substance use disorder, giving patients clarity and focus to concentrate on recovery. Thanks to a recent report, that has also been revealed to be the case for those suffering with long COVID too, with Lauren Nichols, a long COVID sufferer from Chicago being prescribed the drug by her doctor. She found that the drug helped quell her seizures and headaches, alowing her to think clearly and get on with her life as normal. It's been a similar story for other patients too, and has marked a major breakthrough in the bid to help those who are still suffering in the aftermath of the pandemic.
pharmacybiz

Drug prices - what contractors need to be aware of - 0 views

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    There has been a lot of coverage in the national and pharmaceutical press of the prices being charged to pharmacy owners for certain medicines. Leaving aside the reasons for steep price rises, I have been asked on social media and elsewhere whether pharmacy owners can refuse to supply prescribed medicines if they would make a significant financial loss. Legal obligation The first thing to point out is that the National Health Service Act 2006 imposes a legal duty on the Secretary of State and NHS England to make arrangements for people to receive sufficient prescribed drugs. These arrangements involve the publication of the Drug Tariff. The Drug Tariff includes reimbursement prices or a method for determining prices. Various factors can be taken into account in determining reimbursement prices. The Drug Tariff does not provide a pound for pound reimbursement for medicines that pharmacies supply on NHS prescriptions.
pharmacybiz

Novo Nordisk:Supply constraints on diabetes drug - 0 views

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    Danish drug developer Novo Nordisk on Wednesday (February 1) warned of supply constraints on its best-selling drug. The company, which develops diabetes and obesity drugs, said it expected "periodic supply constraints" this year, partly driven by higher than expected demand for its blockbuster diabetes drug, Ozempic, and manufacturing constraints. "Supply of Ozempic cannot keep up with demand in some markets," Novo's Chief Financial Officer Karsten Munk Knudsen told journalists on Wednesday, but said Ozempic was available in the United States, the firm's biggest single market. Shortages of human growth hormone would also cause sales in its rare disease franchise to drop by a "mid-single digit" percentage in 2023, as its Norditropin drug would be out of stock in certain markets, Knudsen said.
pharmacybiz

Eli Lilly drug slows Alzheimer's by 35%:Company - 0 views

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    An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death. The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB). Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced cognitive decline by 27% in patients with early Alzheimer's in a study published last year. The results drove Lilly's shares to a record high, up more than 6% at $429.85. Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory. "It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful." Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.
pharmacybiz

GSK antibiotic drug to treat uncomplicated UTIs - 0 views

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    British pharmaceutical giant GSK said on Saturday (April 15) its oral antibiotic drug to treat uncomplicated urinary tract infections (uUTI) in female adults and adolescents met the main goals in late-stage trials. The drug, gepotidacin, in phase III trials, met its primary goals of being on a par or better than nitrofurantoin, the current standard of care for the treatment of uUTIs, the company said. GSK plans to submit results of the trials to the United States Food and Drug Administration for review later in the second quarter. The drug, if approved, could become the first new type of antibiotic, which is critically important for countering drug-resistant infections, to treat uUTIs in 20 years, the company said. "Gepotidacin, if approved, will offer a much-needed additional oral treatment option for patients at risk of treatment failure associated with resistance or recurrence of uUTI," Chris Corsico, senior vice president of development at GSK, said.
pharmacybiz

Rogue Chemist Jailed: Inside the Prescription Drug Scandal - 0 views

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    A drug dealer who was operating as an "unlicensed chemist" and selling prescription drugs online has been jailed for six years, according to Essex Police. The convict, identified as 49-year-old Christopher Depp, aka David Jones, was supplying a range of drugs from his home to "vulnerable people" using the postal service, local police revealed on Friday (February 16). Police conducted a search operation at his address in Wood Street, Chelmsford, in July last year and found more than 50,000 pills and tablets of varying types, stashed in toolboxes and spaces around the property. To process the large-scale sale and shipping of controlled drugs across the UK, Depp had set up a room in his property as an office space. He promoted the sale of medications through various social media platforms and messaging applications, and accepted payment from his large customer base using "fraudulently obtained" bank accounts.
pharmacybiz

DND list : Twenty-eight new medicines added - 0 views

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    The Department of Health and Social Care (DHSC) has added further 28 new products to the list of 'Drugs for which Discount is Not Deducted' (DND) in Part II of the Drug Tariff from 1 August 2022. PSNC said, "It will continue its work to assess whether other drugs and appliances fulfil the current DND entry requirements under either the 'Group' and 'Individual item' criteria and make applications to NHSBSA and DHSC, accordingly." A total of 529 products have been granted DND status following checks made by PSNC within the past 26 months.
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Eisai :Files for approval of Alzheimer's drug in Europe - 0 views

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    Japanese drugmaker Eisai said on Tuesday (January 10) it had submitted a marketing application to the European health regulator for review of its Alzheimer's drug lecanemab, which was recently granted accelerated approval in the United States. The drug, developed in partnership with Biogen, is an antibody that has been shown to remove sticky deposits of a protein called amyloid beta from the brains of those in the early stages of the mind-wasting disease. Nearly all previous experimental drugs using the same approach have failed. The company's application to the European Medicines Agency is based on results from a late-stage study in which the drug was shown to slow down the rate of cognitive decline in patients with early Alzheimer's by 27 per cent, compared with a placebo. Eisai also reiterated its plans to apply for marketing authorization of the drug in Japan by the end of its business year on March 31.
pharmacybiz

Recall report of blood pressure drugs 'misleading' - 0 views

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    The Royal Pharmaceutical Society (RPS) has confirmed that the recall of blood pressure drugs amlodipine and olmesartan by the Food and Drug Administration is only for the US market and will not have any impact in the UK. MHRA also clarified that the manufacturer of these drugs, Macleod Pharmaceuticals, does not supply amlodipine medicines in the UK. It was published online in both the Daily Record and Daily Express on the morning of Monday, March 21, that the drugs had been recalled in the US by the FDA due to deviations from standard manufacturing protocols by the manufacturer. RPS intervened to ensure the articles were edited to make clear that this is not an issue in the UK after confirmation from the MHRA. Amlodipine tablets from Macleod Pharmaceuticals aren't available for wholesale distribution in the UK.
pharmacybiz

Pharmaceutical Packaging : 6 Tips For Choosing It - 0 views

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    Product packaging affects the effectiveness of pharmaceuticals to a great extent. This is why pharmaceutical companies ensure they choose appropriate packaging for drug products. Drug packaging is not always an easy job. However, the tips in this article will help you select the proper pharmaceutical packaging for drug products without stress. What Does Pharmaceutical Packaging Entail? Pharmaceutical packaging involves using packaging containers with safety closures such as a lidding film to hold pharmaceutical products. This is done to keep them safe and effective. The most commonly used packaging materials in the pharmaceutical industry are metals, glass, and plastics. These materials are used for different reasons and different products. In short, a pharmacist considers several factors regarding a product and its target audience before choosing a packaging material for pharmaceutical formation. Why Appropriate Packaging Matters Many benefits come with appropriate pharmaceutical packaging. These benefits make it essential to package drug products in the best ways possible. When pharmaceutical items are properly packed, they can reach patients for a safe prescription. As a result, the drug stands a higher chance of achieving its prescription purpose. More so, properly packaged drug products are safer to consume and can be trusted.
pharmacybiz

Drug shortage: Fixing the medicines shortage crisis - 0 views

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    From over-the-counter flu tablets to crucial antibiotics and antidepressants, medicines are running scarce in UK pharmacies this year, causing concerns among patients, the government, and the wider pharma industry. Drug shortages have accelerated over the past year due to a clutch of problems including the after-effects of the pandemic on supply chains, the war in Ukraine, and soaring input costs weighing on manufacturers. More recently, a sudden spike in respiratory infections - another by-product of Covid-19 that neither pharma companies nor the government were able to predict - has deepened the crisis, with 70 commonly taken drugs out of stock in Britain as of February. The problem is not unique to the UK. In a recent survey of groups representing pharmacies in 29 European countries, three quarters said shortages were worse this winter than a year ago, with a quarter reporting more than 600 drugs in short supply. The US is also facing significant shortages of popular prescription drugs like amoxicillin and Adderall, an ADHD medication. To some extent, the current disruption is laying bare wider challenges facing the industry for several years that were only exacerbated by the pandemic. The over-reliance on foreign suppliers for most active pharmaceutical ingredients (APIs) is one of them. This model has left companies more susceptible to supply shocks, which have in turn increased in frequency and severity due to pandemic lockdowns, the war in Ukraine and other issues such as the shortage of shipping containers. Pharma's long and opaque supply chains, alongside regulatory complexities, also mean it is taking longer for drugmakers to reconfigure manufacturing and distribution in times of additional need.
pharmacybiz

Further 18 Products Added To DND List-Pharmacy Business - 0 views

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    A further 18 new products have been entered the list of 'Drugs for which Discount is Not Deducted' (DND) in Part II of the Drug Tariff on 1 November, following applications made by the PSNC. This takes the number of products added to the DND list by the Department of Health and Social Care (DHSC) and the NHS Business Services Authority (NHSBSA) in the last 18 months to over 400. The latest list of products include Aciclovir 200mg/5ml oral suspension sugar free, Acitretin 25mg capsules and Strattera 4mg/1ml oral solution. The DND list is updated monthly by the DHSC and includes grouped and individual items, the latter being separately listed in Part II of the Drug Tariff. Any items covered by the 'Group Items' heading are not listed again individually in Part II. See here to see a list of all the monthly changes to the DND status of products.
pharmacybiz

Novartis:Operating profit grow amid spin off Sandoz generics - 0 views

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    Novartis on Wednesday (February 1) predicted that core operating income would grow in a "mid single digit" percentage range in 2023 following stagnation last year, as the Swiss drugmaker prepares to spin off its Sandoz generics business. Full-year core operating income was broadly flat at $16.7 billion, it said in a statement, coming in slightly below market expectations of $16.8 billion. Adjusted for overall negative currency effects, group sales in 2022 advanced 4 per cent to $50.5 billion as gains from heart failure drug Entresto and multiple sclerosis (MS) drug Kesimpta were partly offset by competition from cheap generic copies of established MS drug Gilenya. Novartis said it was on track to spin off its generics unit Sandoz in the second half of the year as part of its effort to sharpen its focus on its patented prescription medicines. Analysts have welcomed a programme unveiled in 2022 to trim costs and cut 8,000 jobs and plans to focus on fewer therapy areas and drug technologies. But the market has been underwhelmed by prospects for medium-term growth from new drugs.
pharmacybiz

Elsevier PharmaPendium : Empowering Pharma Excellence - 0 views

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    The global company in information and data analytics, Elsevier launched a platform, PharmaPendium for drug candidates. It is an effective tool that provides data including complete Food and Drug Administration (FDA) and European Medicines Agency (EMA) approval packages for drug development. The platform is supported by the FDA, the Medical Devices Agency (PMDA) and the top 20 global pharma companies. Olivier Barberan, Director of Translational Medicine Solutions spoke about how "improved access to highly relevant data plus predictive tools enhances regulatory success, safeguarding the massive investments of pharma companies." "Translation of preclinical research findings to humans in an efficient but safe way is one of the greatest challenges facing drug developers. We designed the new PharmaPendium to solve this," he added.
pharmacybiz

Global Drug Shortages: Behind the Crisis in Medication Supply - 0 views

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    Drug shortages have become a global issue, with many countries struggling to maintain a consistent supply of common medications, including antidepressants, immunosuppressants and drugs to treat type 2 diabetes and ADHD. Earlier last month, the British Generic Manufacturers Association (BGMA), the trade body for off-patent medicines, warned that 111 products were facing supply problems, the highest on record in the UK, and more than double the number recorded at the start of 2022. More than half of products affected (55) are branded generic drugs, which represent 10 per cent of prescription products used in the UK. The trade body blamed the escalating rebate rate of the government's voluntary scheme for branded medicine pricing and access (VPAS) for these shortages, but Brexit is also cited as another reason for the problem.
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