Group items tagged

The Medicines and Healthcare products Regulatory Agency (MHRA) has introduced a new tool to check the eligibility for marketing authorisation applicants. Applicants are now required to use the online 'Eligibility Checker' tool to determine whether their Marketing Authorisation Application (MAA) is suitable for the Agency's International Recognition procedure (IRP), which will become operational on 1 January 2024. The tool will also help applicants identify which route (A or B) to follow, before submitting their IRP application. Julian Beach, MHRA Interim Executive Director of Healthcare Quality and Access, said that the tool has been tailored to "facilitate a smooth and efficient process for marketing authorisation applicants."

The Pharmacists' Defence Association (PDA) said it has supported the application of the Royal Pharmaceutical Society (RPS) to rejoin the International Pharmaceutical Federation (FIP), the global body representing the interests of pharmacy. Under FIP rules, if a new application from an additional organisation from the same country applies to join, the existing members in that country are consulted about that decision and are asked for their approval before FIP council members determine if the application is accepted. The PDA joined FIP earlier this year, and RPS, which has decided not to renew FIP membership at the end of last year, has now submitted a fresh application to join. RPS decision to leave, taken after a vote, has invited much criticism. The organisation, a founding member, had attributed high membership fees and associated costs for leaving FIP While the PDA has confirmed that it would not oppose the membership application of the RPS, it has asked FIP to find a suitable method to ascertain a transparent declaration of membership numbers from the RPS in the event of FIP Council deciding to admit RPS.

Computer Science Tuesday, April 25, 2023 Computer hardware Computer hardware is the physical components that make up a computer system. It includes everything from the central processing unit (CPU) to the monitor, keyboard, and mouse. Understanding the different types of hardware and how they work together is essential for anyone who works with computers. In this article, we will explore the various components of computer hardware, including internal and external components, and the peripherals that connect to them. We will also discuss the importance of hardware maintenance, the latest advancements in computer technology, and factors to consider when choosing the right hardware for your needs. Whether you are a computer technician, a gamer, or simply someone who uses a computer for everyday tasks, this article will help you better understand the world of computer hardware. Introduction to Computer Hardware Computer hardware refers to the physical components that make up a computer system. It includes everything from the processor and memory to input/output devices such as the keyboard and monitor. In this article, we will explore the different types of computer hardware and their functions. What is Computer Hardware Computer hardware refers to the physical components of a computer system. It includes all the components that can be touched, seen, and used to interact with a computer, such as the monitor, keyboard, and mouse. Hardware is different from computer software, which refers to the programs and applications that run on a computer system. History of Computer Hardware The history of computer hardware dates back to the 1820s when Charles Babbage, an English mathematician, and inventor, designed the first analytical engine, which was considered to be the first mechanical computer. With time, more complex electronic computers were developed, including the first Intel microprocessor in 1971. Since then, computer hardware has continued to evolve, becoming

The Department of Health and Social Care has updated the list of community pharmacies eligible for the Pharmacy Access Scheme (PhAS) and approved 43 cases out of 63 applications, bringing the the total number of eligible pharmacies in England to 1,445. Earlier this year, NHS England and NHS Improvement (NHSE&I) invited community pharmacy contractors to apply for a review if they believed there were any inaccuracies in relation to pharmacy premises addresses or unforeseen circumstances affecting access, such as a permanent roadblock. Submitted applications were reviewed by the relevant NHSE&I regional pharmacy contract team, and determined by the relevant pharmaceutical services regulations committees (PSRC). Due to the workload pressures seen over winter, the review deadline was extended, giving contractors applying for a review two full months to complete their applications. This also pushed back the announcement of the outcome of the review, but where an application has been successful, PhAS payments will be backdated to the start of the scheme.

Boots has welcomed job applications from LloydsPharmacy staff impacted by the news of closure of all its branches located in Sainsbury's before the end of 2023. The company is recruiting for more than 1,500 pharmacy roles nationwide. Vacancies span pharmacy roles at all levels - from Pharmacy Advisors (Dispensers) and Trainee Pharmacists to experienced Pharmacists looking to develop their careers. Sebastian James, Managing Director of Boots UK & ROI, said: "Pharmacies deliver vital healthcare in the heart of communities. News of the closure of LloydsPharmacy branches within Sainsbury's stores will no doubt have an impact on many talented pharmacists as well as their patients. "We have many roles available at Boots and welcome applications from LloydsPharmacy employees affected by the closures. Patients who are worried about their future pharmacy provision can check our store locator online to find out where their nearest Boots store is - our pharmacy team members are ready to help." There are over 2,200 Boots stores across the UK and 85% of the population live within 10 minutes of a Boots store.

Tynor Elastic Knee Support Elastic knee Support is a versatile knee support which offers the advantage of controlled compression around the knee and a rigid lateral immobilization and support of a splint. It allows normal flexion and free movement of the knee joint. Patellar Opening. Easy application. Controlled compression. Perfect lateral splinting. Mimics movement of natural joint. Tynor Elastic Knee Support Features Strong aluminum Hinges Rigid side splinting Free flexion movement. Open patella design Release patellar pressure. Hold the patella in position Can be used for Patellofemoral diseases Wrap design Easy application and removal on swollen or asymmetric knees Easy application and removal for weak or geriatric patients. Allows customized compression Offers flexibility in sizing Patellar cushion Improves patient comfort Improves compression Improves grip of the product Large dorsal opening Ensures no buckling on bending No vaso constriction on the dorsal area Improves patient comfort and compliance.

Net neutrality is one of the biggest issue debated globally by the telecom regulators and it is also in the process of finalising what will be a landmark recommendation for Indian telecom. The important aspects of Net neutrality are: Internet service providers should enable access to all content and applications regardless of the source. The Internet service provider from whom buy internet pack, should not under any circumstance be able to control how exactly use it and it's upto how you use the data. All websites can co-exist without hampering others and all websites are accessible at the same speed and no particular website of application is favoured. All web sites and content creators are treated equal, and it don't have to pay extra for faster Internet speed to a particular site/service. The concept of net neutrality doesn't exist legally but most companies have Net Neutrality is simply the Internet Freedom - Free, Fast and Open Internet for all. Net Neutrality is the principle that Internet service providers (ISPs) should give consumers access to all and every contents and application on an equal basis, treating all Internet traffic equally. Today, if there's something that makes everyone across the world "Equal" is nothing but the Internet. Equality over the Internet means, the richest man in the world has the same rights to access the Internet as the poorer. And this is what "Net Neutrality" aims at adhered to it until now. With the Internet taking the world into its folds, Internet Service Providers across the world are trying to encash this potent commodity and trying to control the traffic. Karma Healthcare KP-80 Standing Wheelchair is a compact and fully powered wheelchair designed for budget. The front-wheel drive provides agile control for the chair to negotiate various indoors and out. It comes with the innovative seat and wide range of power backrest angle adjustment (80~120 degree).

Tynor Wrist & Forearm Splint Right/Left is designed to provide comfortable and firm support to the wrist as well as to the forearm. It effectively works during various orthopedic conditions. It will keep the wrist in the functional position and speed up the recovery process. It will feel comfortable and relieved after applying this wrist and forearm support. The PUF fused fabric provide comfortable and smooth feel which does not cause any rashes on the skin. It allows proper ventilation system to the skin area and also the skin to breathe properly. It has aluminum splints which are easy to remove and apply as well as offers a better grip and a snug fit. It also has long length that will permit the easy movement. This brace enables free finger movement. It has a hook loop closure system which provides optimal compression and it can easily adjust it as per the requirement. Its brace has an in-built thumb opening which keeps the thumb relaxed and free from pressure. Tynor Wrist & Forearm Splint (Right/Left) Wrist and Forearm Splint is designed to immobilize and provide firm and comfortable support to hand and wrist in various orthopedic conditions. It maintains the wrist in the functional position. Aesthetically appealing. Customizable splint. Perfect immobilization. Controlled compression. Anatomical thumb opening. Tynor Wrist & Forearm Splint (Right/Left) Features Made out of PUF fused Matty fabric Breathable Excellent aesthetics Improved comfort Enhanced life. Removable, Aluminum Splints Customized fitting Required degree of dorsi-flexion can be achieved Very good grip and immobilization Design features Long length of the brace, ensures enhanced immobilization Brace abuts the Palmer crease , allows free finger movement. Elegant tabs , allow easy application and removal Elegant tabs, also enhance the aesthetics of the product. Black Color, enhances the aethetics Hook loop closures Easy to apply and remove Ensures optimal compre

Wrist and Forearm Splint is designed to immobilize and provide firm and comfortable support to hand and wrist in various orthopedic conditions. It maintains the wrist in the functional position. Tynor's Wrist & Forearm Splint Right/Left Extra Large is made out of very sturdy PUF fused fabric & malleable, anatomically shaped splints. Designed for perfect support & immobilization of wrist & forearm. Tynor Wrist & Forearm Splint Right/Left is designed to provide comfortable and firm support to the wrist as well as to the forearm. It effectively works during various orthopedic conditions. It will keep the wrist in the functional position and speed up the recovery process. It will feel comfortable and relieved after applying this wrist and forearm support. The PUF fused fabric provide comfortable and smooth feel which does not cause any rashes on the skin. It allows proper ventilation system to the skin area and also the skin to breathe properly. It has aluminum splints which are easy to remove and apply as well as offers a better grip and a snug fit. It also has long length that will permit the easy movement. This brace enables free finger movement. It has a hook loop closure system which provides optimal compression and it can easily adjust it as per the requirement. Its brace has an in-built thumb opening which keeps the thumb relaxed and free from pressure. Wrist and Forearm Splint is designed to immobilize and provide firm and comfortable support to hand and wrist in various orthopedic conditions. It maintains the wrist in the functional position. Aesthetically appealing. Customizable splint. Perfect immobilization. Controlled compression. Anatomical thumb opening. Tynor Wrist & Forearm Splint (Right/Left) Features Made out of PUF fused Matty fabric Breathable Excellent aesthetics Improved comfort Enhanced life. Removable, Aluminum Splints Customized fitting Required degree of dorsi-flexion can be achieved Very good grip and immobilizat

Tynor Leg Traction Brace Leg traction brace is a traction halter applied to the leg for below knee traction. It offers a distinct advantage of a very large holding surface area, ease of application and removal, reuse and patient comfort. Easy application & removal. Can be used for geriatric/ weak skin. Ideal for sensitive skins. Easy monitoring. Distributes pressure evenly. Tynor Leg Traction Brace Features Three-layered PU bonded fabric offers: Soft feel and plush looks through the top layer. Comfortable cushioning through the middle Polyurethane layer. Inner layer provides good frictional characteristics. Multiple hook loop closures Ensure controlled compression. Easy application and removal No loosening, less monitoring Large skin contact area Ensures no vaso-constriction. Eliminates need of an adhesive. Convenient and quick to apply Ensures no skin peeling. Ideal for weak or geriatric skins Tynor Leg Traction Brace Measurements Measure circumference around calf- approx. 6" below knee

The General Pharmaceutical Council (GPhC) has announced that the new requirement for independent prescribing courses will be applicable from 1st of October 2022. Pharmacists currently taking independent prescribing courses and those who apply before 1 October won't be affected by the changes. The new guidance was agreed at the council meeting on 8 September and went to the initial education and training Advisory Group on 22 September where it was well received, the GPhC said. "The guidance is now being finalised to reflect the discussions at the Council meeting and the initial education and training advisory group and will be published in October." The new guidance is relevant for both course providers and applicants and gives some specific suggestions and examples of what we may expect. It will support consistency in the way education providers applied the new standards and will help individual pharmacists to understand the relevant experience they would need before enrolling on a course.

The Leverhulme Trade Charities Trust (LTCT) is set to provide financial aid for the families of those working in the convenience, grocery, and pharmacy trades starting next month. In an announcement, the Trust shared that the applications for the academic year 2024/25 for undergraduate bursaries will start from August 1 till October 15. LTCT bursary schemes are intended for university students whose parent or carer is "employed in an eligible profession, such as convenience retailer, supermarket store worker, or pharmacy technician". According to the charity's bursary scheme, successful applicants can receive up to £3,000, which can be put towards tuition fees, course materials, equipments, or even travel costs. "With the charity's core belief that everyone should have the opportunity to reach their academic potential", LTCT believes. The bursary scheme will help alleviate some of the financial pressure on students interested in pursuing higher education and their parents. In 2024, the total number of bursaries awarded since the scheme launched is expected to exceed 5,000, totalling £28million worth of financial aid.

Tynor Mallet Finger Splint Mallet finger Specially design to correct the mallet finger deformity. Designed to support the dip joint in hyper- extension, while permitting unrestricted movement of the PIP joint. Sleek and convenient. Customizable dorsiflexion. Comfortable cushioning. One universal size. Tynor Mallet Finger Splint Features Coated aluminum body Malleable can be bent and customized Strong, provides rigid immobilization Light weight Ergonomic design Highly practical design to maintain the requisite hyper extension of DIP joint Well ventilated and comfortable Sleek and simple -Better compliance Easy application and removal. Ethafoam lining High cushioning Enhanced comfort Easy to clean and maintain. Inbuilt Hook loop fasteners Close fitting and excellent grip Easy application and removal. Tynor Mallet Finger Splint Measurements Length of Fingers Size Chart - Size Inches CM Universal Below 2-4 Below 5-10

Tynor Anklet (Pair) Anklets are tubular supports widely used in orthopedic practice to provide mild compression, warmth & support to the ankle joint, to allay pain and inflammation generally associated with old age, arthritis, sports etc. Four way stretch Two layered fabric Hypoallergenic Uniform compression Simple pull on application Tynor Anklet (Pair) Features Bilayered , cotton on the inside Dermophillic interpahse with the skin Better sweat absorption Better comfort Better patient compliance. No allergies or rash Bilayered, nylon on the outside Ensures long life Excellent aesthetics Color fastness. Two layers enclose air space retains body heat effectively Provides therapeutic warmth and assuring support to the knee. Four-way stretchable seamless tubular fabric Effective compression Enhanced comfort. No vaso constriction. Adjusts compression even on uneven diameters Simple pull on application improves patient compliance. Tynor Anklet (Pair) Measurements Measure circumference approx 2 inches above the ankle joint. Size Chart - Size Inches CM Small 7.2-8.4 18-21 Medium 8.4-9.6 21-24 Large 9.6-10.8 24-27 XL 10.8-12 27-30

Tynor R O M Knee Brace Prefabricated, custom adjusted R.O.M. Knee Brace controls and restrict flexion/extension of the knee joint through a multi-point joint fixation system to allow a range of motion or immobilization to the knee. Universal design allows it to be used on quite a big range of population and for a multiple orthopedic problems associated with knee joint. Immobilization at any angle Controlled motion between any two angles Quick and easy application and removal. Tynor R O M Knee Brace Features R.O.M. Dial 0 to 120 degree flexion. 0 to 60 degree hyper extention Locking at any angle or motion between any two angles possible Interval of 10 to15 degrees Pleasurable locking, using easy pull mechanism Neoprene Liner with Silicone Coating Enhanced product grip Less slippage of product High cushioning coefficient and more comfort Less discomfort of tight straps Ergonomic Design Light in weight Bilateral symmetrical Improved patient compliance Easy removal and application Universal design, one size fits all Straps with Reverse Buckle Mechanism Enhanced grip Easy to wear Controlled tightening.

Tynor Functional Knee Support is specially designed to support knees which are injured or not working properly due to old age. It stabilizes knees during rotational and anteroposterior forces and cures the ligamentous knee injuries. It provides support to the knees by wrapping around them and thus facilitates their compression. It provides flexibility and easy movement of the knee. It is made of soft, durable fabric which can be stretched in four ways. It mimics the natural knee joint. It can bear the load and shock exerted on it from the external forces leaving the knee totally free from pressure. It contains no buckling or vaso constriction which might hinder comfort. It ensures the proper circulation of blood. It compresses the patellar region and hold it in right position and thus can be used for patellofemoral diseases. It is easy to maintain. Tynor Functional Knee Support Functional knee Support is an anterior opening device, which offers the advantage of controlled compression around the knee and a rigid lateral support and immobilization. It allows normal flexion and free movement of the knee joint. Anterio Open able Easy application Controlled compression. Perfect lateral splinting. Anatomical design. Tynor Functional Knee Support Features Bi axial heavy duty aluminum hinge Mimics the natural knee joint Ensures full weight bearing. Allows free flexion movement Four way stretchable fabric Controlled and comfortable compression No buckling No vaso constriction Enhanced comfort Open patella design Release patellar pressure Hold the patella in position Can be used for Patellofemoral diseases Wrap design with anterior closing Easy application and removal on swollen or asymmetric knees Easy application and removal for weak or geriatric patients. Allows customized compression Offers flexibility in sizing Ergonomic design Anti tourniquet effect - ensures no constriction to blood flow Better grip of the product to the bo

The regulators have added 10 new products to the 'Drugs for which Discount is Not Deducted' (DND) list from Thursday (01 June). Community Pharmacy England on behalf of its members had made further applications to the Department of Health and Social Care (DHSC) and the NHS Business Services Authority (NHSBSA), resulting in the inclusion of 10 new products in the DND. More than 610 products are granted DND status following checks made by Community Pharmacy England's dispensing & supply team over the past 3 years to ensure fair reimbursement for our members. The DND list is updated monthly by the DHSC and includes grouped and individual items. Individual items are separately listed in Part II of the Drug Tariff. Any items covered by the 'Group Items' heading are not listed again individually in Part II. "We will continue our work to assess whether other drugs and appliances fulfil the current DND entry requirements under either the 'Group' and 'Individual item' criteria and make applications to NHSBSA and DHSC, on behalf of our members accordingly," said Community Pharmacy England.

Department of Health of Social Care (DHSC) has confirmed that the Dexcom One Transmitter will be added to Part IXA of the March 2023 Drug Tariff. "Previously, patients were advised to obtain the free-of-charge Dexcom One transmitters directly from the pharmacies, without a prescription, as the original Drug Tariff application for the transmitter was unsuccessful," said the Pharmaceutical Services Negotiating Committee (PSNC) It has raised concerns with DHSC and Dexcom that these distribution arrangements for transmitters are unacceptable because they result in extra unfunded activity for community pharmacies. Both, DHSC and Dexcom acted upon these concerns by agreeing to add the Dexcom One transmitter to the Drug Tariff from March 2023. At the same time, Dexcom One CGM System (containing 1 sensor, 1 sensor applicator, 1 transmitter) will also be added to the March Drug Tariff.

WHAT IS PROTEINASE K MADE OF? Proteinase K is known enzyme belonging to the class of serine proteases that cleave adjacent to the carboxylic group peptide bonds of aromatic and aliphatic amino acids. It's also exhibited a very broad cleavage specificity. The enzyme was discovered in extracts of the fungus Engyodontium album. HOW DOES PROTEINASE K WORK? In molecular biology, main application of proteinase K is to digest proteins during nucleic acids purification in order to remove protein contaminants: - Proteinase K quickly inactivates nucleases (enzymes that digest nucleic acids) that degrade DNA or RNA molecules during the cleansing. - Proteinase K is activated by calcium. It does not affect the activity of the proteinase, but protects again autolysis, improves thermal stability, and regulates substrate binding capacity. To increase the stability of Proteinase K, thereby enhancing its action, Urea as well as SDS (sodium dodecyl sulfate) or elevated temperature at 37-60C is commonly used. Inactivation of Proteinase K is occurring at temperature above 65C. WHAT IS THE PURPOSE OF PROTEINASES? Proteinase K is used to break down proteins in cell lysates (tissues, cell culture cells) and to release nucleic acids due to its action described above. Proteinase K application purpose: DNA isolation from various tissues; Removal of DNAses and RNAses: Proteinase K and RNases can act together in the lysis buffer to degrades contaminating RNAs and proteins;

Japanese drugmaker Eisai said on Tuesday (January 10) it had submitted a marketing application to the European health regulator for review of its Alzheimer's drug lecanemab, which was recently granted accelerated approval in the United States. The drug, developed in partnership with Biogen, is an antibody that has been shown to remove sticky deposits of a protein called amyloid beta from the brains of those in the early stages of the mind-wasting disease. Nearly all previous experimental drugs using the same approach have failed. The company's application to the European Medicines Agency is based on results from a late-stage study in which the drug was shown to slow down the rate of cognitive decline in patients with early Alzheimer's by 27 per cent, compared with a placebo. Eisai also reiterated its plans to apply for marketing authorization of the drug in Japan by the end of its business year on March 31.