The Medicines and Healthcare Products Regulatory Agency (MHRA) has approved the marketing authorisation of Adtralza, a dermatological solution developed
by Danish specialist LEO Pharma. This injectable solution contains 300 mg of tralokinumab in a 2 mL pre-filled pen and will be available for tralokinumab patients
in the UK from early 2024.
Tralokinumab is indicated for treating moderate-to-severe atopic dermatitis in adult and adolescent patients aged 12 and older who require systemic therapy, Leo
Pharma said in a statement. It is a fully human monoclonal antibody developed to specifically bind to and inhibit the IL-13 cytokine. Previously, it was available
in a 150 mg in 1 mL pre-filled syringe.
According to Leo Pharma, the 300 mg tralokinumab in a 2 mL pre-filled pen offers a streamlined administration for both patients and prescribers. It begins with an
initial 600 mg dose in two injections, followed by a single 300 mg maintenance dose administered every other week.
"We're pleased that this simplified administration method for tralokinumab will soon benefit eligible atopic dermatitis patients in the UK. It aligns with our
commitment to elevate the standard of care and support for individuals with skin conditions," said Leanne Walsh, Vice President and General Manager of UK and
Ireland at LEO Pharma.
Endometriosis is known as one of the complications of women's reproductive parts. Also, research says that it affects primarily 10% of women starting their adolescence. Still, many believe that it is not as harmful an illness as it sounds, without having any idea that it is...
Couples experiencing infertility also deal with mental health related stress while trying to conceive. If you or your partner is experiencing any mental health related issue in your pregnancy journey, top fertility experts can help
The UK Health Security Agency (UKHSA) said last week (Aug 5) there were "early signs" that the monkeypox outbreak was plateauing across the country and that
its expansion had slowed.
"While the most recent data suggests the growth of the outbreak has slowed, we cannot be complacent," Dr Meera Chand, director of clinical and emerging infections
at UKHSA, said.
There were 2,859 confirmed and highly probable cases of monkeypox in the UK as of Aug. 4, with nearly 99 per cent of the cases among men, the country's health
authority said in a statement.
The recent analysis by the UKHSA showed that "monkeypox continues to be transmitted primarily in interconnected sexual networks of gay, bisexual, or other men who
have sex with men", it added.
British authorities in June were recommending gay and bisexual men at higher risk of exposure to monkeypox be offered a vaccine, as the outbreak of the viral disease
had gathered pace, mostly in Europe.
If you have asthma, it's important to know when you should see a doctor about an asthma flare-up. A flare-up is a sudden increase in your symptoms, which can
include coughing, wheezing, chest tightness, and shortness of breath. Flare-ups can be mild or severe, and they can occur at any time. If you're not sure whether
you're having a flare-up, here are six obvious signs that it might be time to see a doctor.
1. YOU'RE USING YOUR INHALER MORE THAN USUAL
If you have asthma, you likely have a rescue inhaler that you use when you're having symptoms. This inhaler contains a medication that can quickly relieve your
symptoms. If you find that you're using your rescue inhaler more often than usual, it could be a sign that your asthma is getting worse and you need to see a doctor.
By seeking a doctor near me online, you can find a reputable physician who will accurately diagnose and treat your asthma. Always look for a second opinion, as one
doctor's opinion might differ from others. For example, some doctors might recommend that you use a daily inhaler, while others might only recommend using it when
you're having symptoms.
Treating your scalp the same way you treat your skin is one of the most crucial life lessons. This reasoning is supported by the fact that your scalp is composed of skin and functions similarly.
Thus, throughout the winter, the scalp experiences the same level of skin dryness as the rest of our bodies. Dandruff, flaking, and irritation develop as a result of your head. Winter dandruff, in contrast to summer and monsoon flaking, is a direct result of the scalp being dry from the chilly air. Add to that the fact that you always keep your head covered to stay warm. This creates a comfortable, warm environment for dandruff-producing microorganisms on the scalp.
You need to take care of dandruff as soon as you can since it may be very uncomfortable, especially when those bothersome white flakes appear on dark woolen winter clothing. Here are some suggestions to help you get rid of dandruff:
1. Neem with coconut oil.
The moisturizing benefits of coconut oil may be well known to you. These qualities come from its excellent fatty acid and vitamin content. Wouldn't the ideal defense against dandruff be created if coconut oil and neem, which has antibacterial and antifungal qualities, were combined? 4 teaspoons of coconut oil should be added to 1 teaspoon of neem powder. Depending on how long your hair is, change these amounts.
Read More : https://medium.com/@tribalblackoil/top-5-hair-masks-to-treat-winter-dandruff-2a03163bb4f2
A University College London team of researchers has developed an artificial intelligence (AI) programme that can identify minute brain anomalies that lead to
epileptic seizures.
The algorithm, used in the Multicentre Epilepsy Lesion Detection project (MELD) and which reports locations of abnormalities in cases of drug-resistant focal
cortical dysplasia (FCD) - a major cause of epilepsy - was developed by a multinational team who used more than 1,000 patient MRI scans from 22 international
epilepsy centres.
Brain regions known as FCDs have evolved improperly and frequently lead to drug-resistant epilepsy. Surgery is usually used to treat it, however, finding the
lesions on an MRI is a constant problem for doctors because MRI scans for FCDs can appear normal.
The scientists employed about 300,000 places throughout the brain to quantify cortical properties from the MRI scans, such as how thick or folded the cortex/brain
surface was.
A successful kidney transplant allows the transplanted kidney to take over the vital functions of filtering waste products and excess fluid from the blood.
For many people who suffer from joint pain, the weather can be a big factor in their pain. While joint pain can be caused by many different things, such as
arthritis, injuries, and age, the weather can aggravate and worsen the pain.
Several studies have been conducted over the last several years; however, no concrete evidence supports one theory vs. another.
That said, let's take a closer look at how weather affects joint pain and what you can do to minimize the discomfort.
How Weather Affects Joint Pain
It might seem like an old wives' tale, but there is actually some science behind how weather affects joint pain.
Temperature Changes
The temperature outside can majorly affect how much joint pain you experience. When temperatures drop, your body will get stiffer and more painful joints as the
air around them gets colder. During hot days, the air humidity outside may cause swelling and increased inflammation in your joints which could lead to more pain.
Pressure Changes
Just like a barometer measures changes in atmospheric pressure, so does your body. Pressure changes due to shifts in the atmosphere can affect joint pain because
pressure changes directly impact your joints' lubrication levels. When pressure drops and becomes low enough, it can cause extra friction between bones connected
by tendons or muscles, resulting in more pain than usual.
An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing
what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease.
Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with
early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease
progression and brain cell death.
The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based
on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB).
Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced
cognitive decline by 27% in patients with early Alzheimer's in a study published last year.
The results drove Lilly's shares to a record high, up more than 6% at $429.85.
Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the
disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory.
"It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful."
Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.
Erection problems are common conditions that can affect adult men of any age. General awareness about erection problems has grown in recent years, and men's
partners and society at-large generally view it as a common condition. Indeed, 75% of men and their partners agree that they are a normal part of life for a man.
But despite progress to normalise the condition, the research points to the fact that men still feel responsible for erection problems.
The survey's key findings underscore the multi-faceted social pressure men feel to perform socially, professionally, emotionally, and sexually. 90% of men feel
expected to provide financial support, 80%+ feel they should be in control of their feelings, and 92% think it is expected of them to perform in bed.
Despite erection problems being commonplace, expectations about sexual performance complicate the situation and make a major impact on the lives of those it affects.
When men are confronted with erection problems, 60% expressed feeling disappointed. This disappointment, combined with the difficulty that 1 in 3 men have spoken
about it, has a strong impact on well-being. 36% of men feel their mental health has been impacted by erection problems and leads to a feeling of guilt, and 74% of
men feel responsible for difficulties in achieving or maintaining an erection.
During the coronavirus pandemic many people found themselves working from home, and this has continued to some extent in many businesses. A change in working
environment can bring challenges, one of which can be joint pain and discomfort.
Imagine you have gone from a busy office environment, meeting in boardrooms and visiting the canteen for a coffee, to working at home on your dining room table,
walking several feet to get a cup of tea and sitting back down again, this change in surroundings can have an impact on your joints.
Community pharmacists can be a source of knowledge to help individuals that may be suffering from joint complaints, this may be from the above scenario or just
general aches and pains that come from an office based role.
Firstly, it's important for us to know the effects of sitting down at a desk all day (not a scenario I'm sure many community pharmacists experience daily):
Back pain - is one of the most common complaints. This can be caused by bad posture while sitting too high, too low, or hunched over. While this may present as
just a soreness or discomfort, if not rectified and/or accessed this can lead to some serious health issues such as spinal compression, sciatica or spinal stenosis.
A diabetes medicine, Mounjaro, has been approved by the Medicines and Healthcare Products Regulatory Agency (MHRA) to treat overweight patients.
The weight loss medication originally developed for Type 2 diabetes is now accessible to individuals aged 18 and over who are dealing with obesity and
weight-related health issues.
The active ingredient, tirzepatide, works by making the patient feel fuller and reducing food cravings.
The injection helps individuals lose 20 per cent of their body weight, and are advised to follow a reduced-calorie diet and increase physical activity
simultaneously.
Although it is not authorised to use on the NHS as yet but future approvals can be predicted.
A new study published in The Lancet has revealed that a total of 1.7 million people could be living with dementia in England and Wales by 2040.
The research highlighted increasing numbers of people who will suffer from Alzheimer's.
The disease would massively increase the burden on the healthcare system.
The research was led by University of College London (UCL).
Lead researcher, Dr Yuntao Chen said, "It is shocking to think that the number of people living with dementia by 2040 may be up to 70 per cent higher than if
dementia incidence had continued to decline.
"Not only will this have a devastating effect on the lives of those involved but it will also put a considerably larger burden on health and social care than
current forecasts predict.
The World Health Organization said on Sunday (May 29) that monkey pox constitutes a "moderate risk" to overall public health at global level after cases were reported in countries where the disease is not typically found.
"The public health risk could become high if this virus exploits the opportunity to establish itself as a human pathogen and spreads to groups at higher risk of severe disease such as young children and immunosuppressed persons," WHO said.
As of May 26, a total of 257 confirmed cases and 120 suspected cases have been reported from 23 member states that are not endemic for the virus, the health agency
said in a statement. There has been no reported fatalities so far.
WHO also said that the sudden appearance of monkeypox at once in several non-endemic countries suggests undetected transmission for some time and recent amplifying events.
The agency added that it expects more cases to be reported as surveillance in endemic and non-endemic countries expands.
Monkeypox is an infectious disease that is usually mild, and is endemic in parts of west and central Africa. It is spread by close contact, so it can be relatively easily contained through measures such as self-isolation and hygiene.
People infected with monkeypox can isolate at home if they remain well enough, whilst following measures to limit close contact with others, the UK's health
security agency (UKHSA) said on Monday (May 30), part of guidance designed to curb the country's rise in cases of the viral illness.
More than 300 suspected and confirmed cases of monkeypox have been reported in May, outside of Africa where the virus is endemic. The usually mild illness spreads
through close contact and can cause flu-like symptoms and pus-filled skin lesions.
An additional 71 cases of monkeypox have been identified in England, taking the total number of confirmed cases in the UK as a whole to 179 since early May.
Scientists are looking into what might explain the unusual surge of cases, given most are not linked to travel.
The UKHSA indicated community transmission was occurring in the UK and said infected people should avoid contact with others until their lesions have healed and
the scabs have dried off.
In the anal canal, piles are a collection of irritated or swollen tissues. They can be external or internal to the anus and come in a variety of sizes. Internal piles are typically two to four millimetres above the tip of the anus opening, and they are the most commonly recognised kind. The external piles can be found on the anal area's outside. For any health services you can call on this phone number - 88569-88569 and visit our website - https://www.medpho.com/
Asda Ramsgate pharmacy worker Claire Twyman saved life of a regular patient Rose Doyle by giving her a timely advice to visit A&E after spotting a blood clot on her leg.
Doyle (75) spent five days in Margate Hospital, and after recovering she called in at the store to thank Twyman for her quick-thinking actions.
She handed her a thank-you note which read: "Thank you for making me go to A&E. You may have saved my life, so thank you once again I am really grateful."
Twyman, who has worked at the store for nine years, said: "I was just happy that I was able to help her and give her that advice, which made a difference. It could have been a lot worse if she'd left it. I'm so glad she's okay.
"Rose came over to the pharmacy for advice on her leg. I looked down and told her it was really swollen, and then asked to look at her foot. I thought straightaway that it was a thrombosis, a blood clot. Her toes were very white, but I didn't want to alarm her."
A smattering of monkeypox cases in Britain has prompted authorities to offer a smallpox vaccine to some healthcare workers and others who may have been exposed,
as a handful more cases were confirmed in parts of Europe.
Monkeypox is a usually mild viral illness, characterised by symptoms of fever as well as a distinctive bumpy rash.
There are two main strains: the Congo strain, which is more severe - with up to 10 per cent mortality - and the West African strain, which has a fatality rate of
about one per cent
First identified in monkeys, the viral disease typically spreads through close contact and largely occurs in west and central Africa. It has rarely spread elsewhere,
so this fresh spate of cases outside the continent has triggered concern.
In the United Kingdom, nine cases of the West African strain have been reported so far.
There isn't a specific vaccine for monkeypox, but a smallpox vaccine does offer some protection, a UK Health Security Agency (UKHSA) spokesperson said.
Data shows that vaccines that were used to eradicate smallpox are up to 85 per cent effective against monkeypox, according to the World Health Organisation.
