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Sun Pharma has announced that it will acquire all outstanding shares of Concert Pharmaceuticals through a tender offer for an upfront payment of $8.00 per share of common stock in cash, or $576 million in equity value. The upfront payment of $8.00 per share of common stock in cash represents a premium of approximately 33% to Concert's 30-day volume weighted average price as of January 18, 2023, the last trading day prior to today's announcement. Concert is a late-stage biotechnology company pioneering the use of deuterium in medicinal chemistry. Concert has an extensive patent portfolio, including its lead product candidate deuruxolitinib - an oral inhibitor of Janus kinases JAK1 and JAK2 for the treatment of Alopecia Areata, an autoimmune dermatological disease - which is in late-stage development. It has completed the evaluation of the efficacy and safety of deuruxolitinib in adult patients with moderate to severe Alopecia Areata in its THRIVE-AA Phase 3 clinical program and two open label, long-term extension studies are ongoing in North America and Europe. Sun Pharma's immediate focus would be to follow Concert's plan to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the first half of 2023.

Professional translators recreate texts, not simply matching word-for-word, but understanding the underlying meaning, purpose, and interpretation of the original language, and reproduce it using appropriate terminology and structure to ensure there is no potential for misunderstanding. An experienced technical translator addresses conventions to ensure the meaning of the information is preserved, using medical expertise and quality review processes to adapt documentation to meet the needs of patients, medical practitioners, and peers. Attention to detail is fundamental to medical translations and a non-technical translation is an unacceptably high risk for any organisation involved in publishing or circulating medical information of any kind. WHAT IS MEDICAL TRANSLATION? Medical translation is a technical process where capable translators reproduce content or documentation used anywhere in the medical industry, including psychiatry, systematic reviews, tuition and training, patient communications for pharmaceutical translation services. Important clinical trial translations can include labelling, prescriptions, medical devices and patient records, with millions of medicines and treatments used globally and written in multiple languages. Qualified medical translators must have exceptional linguistic skills but also a thorough understanding of medical sciences in all the native languages concerned. However, the complexity of translating one label or one document into several languages can mean that organisations may assume a simple translation is sufficient - when it is anything but!

Sun Pharmaceutical Industries, India's largest drugmaker by revenue, reported a better-than-expected 5.2 per cent rise in third-quarter profit on Tuesday, driven by higher sales of its specialty drugs. The company, known for its consumer healthcare products such as Revital vitamins and pain relief medicine Volini, said it earned a consolidated net profit of 21.66 billion rupees ($265.23 million) in three months ended Dec. 31, up from 20.59 billion rupees last year. Analysts, on average, had expected the company to report a profit of 21.26 billion rupees, according to Refinitiv IBES data. Total revenue from operations climbed nearly 14 per cent to 112.41 billion rupees. Input costs rose 8.5 per cent. Drug sales in India rose 7.1 per cent to 33.92 billion rupees, whereas sales in the United States climbed 16.6 per cent to 34.66 billion rupees, with each of the two regions accounting for 31 per cent of the company's total consolidated sales. The company, founded in 1983, makes over-the-counter medications, anti-retrovirals and active pharmaceutical ingredients for chronic and acute treatments.

Being able to access high-quality healthcare at the times you need it most is vital. Regardless of whether this is a simple check-up, a medical review or complex surgery, having a suitable healthcare package designed according to your medical needs will be beneficial in the long run. The NHS has recently come under significant strain. Factors such as an increase in the number of patients, reduced funding and increased life expectancy have led to long waiting times and limited treatments. As a result, more individuals are now seeking private healthcare which, while it may be more expensive, offers faster and more effective treatment. Here we'll discuss some of the main benefits of private healthcare and why it is becoming the ideal choice for healthcare in 2023. Reduced waiting times One of the main issues faced by the NHS is waiting times, with some patients being made to wait up to a year for routine hospital care. Currently, ambulance services and A&E units are under unprecedented pressure and it is estimated that hundreds of deaths each week are associated with admission delays. Understaffing has been a chronic issue in recent years in the NHS and is a major threat to the welfare of patients. This has been one of the major concerns that has led to nurses and ambulance staff taking strike action. As nurses and hospital workers are put under higher strain, they are more likely to make mistakes, which could well lead to patients coming into harm and making a claim. Opting for private healthcare guarantees that you are able to access your appointments, surgeries and treatments much quicker, with some flexibility offered to align with your lifestyle. The capacity to bypass the painfully long waiting times ensures you receive the necessary medical attention much sooner and could prevent the emergence of other health complications.

Three batches of Mexiletine hydrochloride 50mg, 100mg and 200 mg hard capsules manufactured by Clinigen Healthcare has been recalled. Pharmacists are urged to quarantine the said batches and return it to the supplier by or before 12 August. Clinigen Healthcare Ltd has initiated a recall of three batches of Mexiletine hydrochloride hard capsules due to a potential risk of under dose or overdose, which could have consequences for the safety of patients. The manufacturer has confirmed that no alternative batches of Mexiletine hydrochloride 50mg, 100mg or 200mg hard capsules will be available until later in the year, therefore the recall of these batches from patients should only be considered where patients have access to appropriate alternative products. See below for more information on resupplying patients with alternative products. "Patients should be advised not to stop any treatments without consulting their relevant healthcare professional. The risks of suddenly stopping medication for ventricular arrhythmias is higher than the potential risk presented by too much or too little of the active ingredient in the capsule."

The Department of Health and Social Care (DHSC) has added further 28 new products to the list of 'Drugs for which Discount is Not Deducted' (DND) in Part II of the Drug Tariff from 1 August 2022. PSNC said, "It will continue its work to assess whether other drugs and appliances fulfil the current DND entry requirements under either the 'Group' and 'Individual item' criteria and make applications to NHSBSA and DHSC, accordingly." A total of 529 products have been granted DND status following checks made by PSNC within the past 26 months.

There are a lot of different beauty procedures that you can try in order to achieve healthy-looking skin. It's essential to consult with a dermatologist or other skin care professional to find out which procedures will work best for you, depending on your skin type and concerns. This article will briefly describe some of the different procedures that are available. Here are some contemporary beauty procedures to consider. 1. SKIN NEEDLING Skin needling, also known as micro-needling, is a minimally invasive procedure that can be used to improve the overall appearance of your skin. It involves using a device with fine needles to create tiny punctures on the skin's surface. Additionally, the effects of skin needling can last long after the initial treatment, making it a popular choice for those looking for a more lasting solution. This helps to stimulate collagen production and can reduce the appearance of wrinkles, fine lines, scarring, and other skin imperfections. Skin needling can be done independently or with other treatments such as radiofrequency therapy or chemical peels. It's important to note that skin needling should only be performed by a licensed professional. 2. RADIOFREQUENCY THERAPY If you're unhappy with the way your skin looks, it may be time to consider a radiofrequency therapy treatment. Radiofrequency therapy uses electromagnetic waves to heat up the deeper layers of your skin, stimulating collagen production and improving blood circulation. This can help to improve the appearance of wrinkles, fine lines, and sagging skin. Additionally, radiofrequency therapy can also help to improve the appearance of cellulite and stretch marks. It's a relatively safe and non-invasive procedure, and there is little to no downtime.

When it comes time to choose a Medicare plan, it can be difficult to know where to start. There are so many factors to consider, from the cost of coverage to the quality of care you'll receive. How do you know which plan is right for you? This article will discuss some of the most important things to keep in mind when choosing a Medicare plan. It will cover everything from drug coverage to hospital and doctor networks. By the end of this article, you'll be able to confidently choose the right Medicare plan for your needs! COST Of course, for most of us, the cost of our healthcare is a major consideration. When you're choosing a Medicare plan, you'll want to make sure that you're getting good value for your money. Be sure to compare the monthly premiums, deductibles, and copayments of each plan you're considering. You may also want to look at the total annual out-of-pocket costs for each plan. This will give you a good idea of how much your healthcare will actually cost you on a yearly basis. If you plan to be using Medicare for insurance, it's important to do your research before enrolling. This way, you can be sure that you're getting the best possible coverage for your needs and budget.

If you know somebody who is regularly binge drinking, it can be difficult to know how to help them. Binge drinking is a serious problem, and can have devastating consequences for the individual involved. This blog post will discuss the signs of binge drinking and provide some tips on how you can help somebody who is struggling with this addiction. 1. FIND THEM A DETOX CENTER If you are concerned that somebody you know is regularly binge drinking, one of the best things you can do is to find them a detox center. Detox centers provide a safe and supervised environment for people to detox from alcohol. They will also be able to provide support and resources to help the individual in their recovery. As professionals at https://www.northridgedetoxcenter.com/ explain, detox centers can offer many different services to help people through the withdrawal process. These services may include medical detox, which can help to manage the symptoms of withdrawal, and counseling services, which can provide support and guidance during this difficult time. It is important to remember that detox is just the first step in recovery and that the individual will need to continue to receive treatment after they have completed detox.

The Pharmacists' Defence Association (PDA) has welcomed the government's defeat in the House of Lords on the Strikes (Minimum Service Levels) Bill. It believes that the proposed Bill, if enacted, would allow the government to dictate minimum levels of service during times of industrial action, enabling employers to name specific employees that they require in work. Those employees could then face losing their jobs if they failed to turn up to work on that day. Trade unions could also be fined if they did not force those named individuals to go to work. PDA director, Paul Day said, "This Bill should be of real concern to pharmacists and other health professionals. The idea of their employer being able to effectively conscript them to work or face the sack does not feel like a positive employment relations environment." The House of Lords has voted for key amendments to the Bill to prevent unions from being required to force workers to comply. This also prevents workers from being forced to work or face the sack and allows for greater consultation and Parliamentary scrutiny on the proposals which the Westminster government is trying to implement. The House of Commons will now be required to vote on the amendments over the next few weeks. Whilst the House of Lords amendments are likely to be defeated, it shows the degree of opposition there is to this Bill.

In response to new research that revealed inequality in menopause support with 51 per cent of women from black, Asian and minority ethnic backgrounds, Holland & Barrett, the UK's leading health and wellness retailer, has decided to continue its menopause campaign work to make "every menopause matter". A quarter of women (26 per cent) from minority ethnic communities say they find it difficult to access menopause support relevant to their specific backgrounds. Alongside support from Olympian and menopause campaigner, Michelle Griffith Robinson and expert, Meera Bhogal, the retailer is launching several new initiatives to make its information and support on menopause more inclusive by offering more diverse and personalised advice and content, tailored to different needs. Almost a third (31 per cent) believe being able to speak to a female healthcare professional of the same ethnicity as them would have made a difference to their menopause experience. Fifteen per cent go as far as saying that communicating in their native language would have made a positive difference. Based on these findings, Holland and Barrett is the first retailer to launch a free, multi-language menopause online consultation service. The service will see trained H&B menopause advisors offering guidance and symptom support in multiple languages, starting with Hindi, Urdu, Gujarati and Punjabi.

Drug addiction poses a serious challenge since it impacts one's physical and mental health. However, the good news is that individuals who complete a drug rehabilitation program can overcome this problem. If you are interested in providing rehab services, there are a couple of things you should know. Read on to learn how to operate a rehabilitation clinic flawlessly. KNOW THE NEEDS OF YOUR CLIENTS The main purpose of drug rehab is to help different people overcome addictions. It is designed to heal the body and mind from the negative effects of addiction. It also teaches the affected individuals to learn to live without using substances. Therefore, your first step is to conduct a comprehensive assessment of each client to formulate a personalized treatment plan. Everyone has unique needs in their recovery journey. Your rehab program can start with detox which is designed to rid the body of substances, although it does not treat addiction. The person affected undergoes different therapies during treatment. Therapy helps them deal with the issues that cause substance abuse and teach them healthier ways of life. Various therapies will be applied throughout the entire treatment process. Therefore, you must choose a suitable therapy for each individual. For instance, motivational interviewing and cognitive behavioral therapy are the most common.

Addiction is a complex disease that can be difficult to overcome. Many people don't realize how serious addiction is and often don't seek treatment until it's too late. If you or someone you know is struggling with addiction, it's important to learn as much as you can about the treatment process. This blog post will discuss six vital things that you should know about addiction treatment. RESEARCH THE VARIOUS TYPES OF TREATMENTS AVAILABLE One of the first things you should do when considering addiction treatment is to research the different types of treatments available. There are many different approaches to treating addiction, and it's important to find one that will work best for you or your loved one. Some common types of addiction treatments include 12-step programs, cognitive-behavioral therapy, detoxification, and medication-assisted treatment. The addiction treatment service providers behind Safe Harbor Treatment Center suggest that you should also consider the length of treatment, as some programs are more intensive than others. It's important to remember that no two people are the same, so what works for one person may not work for another. It's important to find a treatment that will address the underlying causes of addiction and help the individual to develop healthy coping mechanisms.

AstraZeneca said on Monday (June 27) two of its existing therapies were recommended for treating patients with some forms of high-risk breast cancers in the European Union, in a boost to the company's oncology portfolio. Lynparza, a cancer drug developed jointly with U.S.-based Merck, was backed for standalone use or in combination with endocrine therapy in adults with a form of genetically mutated early-stage breast cancer. The drug, which has received a similar recommendation in the United States in March, is a key asset for AstraZeneca. It was recommended in patients with low-to-normal levels of a protein known as HER2 that is the target of several new therapies. Enhertu - developed jointly with Japan's Daiichi Sankyo (4568.T) - was the other drug that was endorsed by the European Medicines Agency for treating an aggressive form of breast cancer characterised by a high rate of HER2.

Making your home both heat and cold-resistant may seem like a daunting task, but there are actually a few simple things you can do to make your home more comfortable no matter the season. In this article, we'll share four ways to make your home both heat and cold-resistant. INSTALL WEATHERSTRIPPING OR CAULKING One of the best ways to make your home more resistant to both heat and cold is to install weatherstripping or caulking around all of the doors and windows. This will help to seal up any cracks or gaps that might let the air escape, making it much easier to keep your home at a comfortable temperature no matter what the weather is like outside. One of the best ways to make your home both heat and cold resistant is to install weatherstripping around all of your doors and windows. This will help to seal in the cool air during the summer and the warm air during the winter, making your home much more comfortable year-round. Another way to improve your home's resistance to extreme temperatures is to caulk any gaps or cracks that you may have in your walls, floors, or ceilings. By doing this, you'll prevent heat or cold from seeping into your home through these tiny openings, saving you money on your energy bills.

The pharmaceutical industry is one of the most important and valuable industries in the world. It is responsible for developing and producing medicines that improve and save lives. However, there are some things you may not know about this fascinating industry. In this blog post, we will discuss six interesting facts about the pharmaceutical industry! 1. THE MANUFACTURING PROCESS OF PHARMACEUTICALS IS HIGHLY REGULATED All pharmaceutical products must go through a rigorous manufacturing process before they can be made available to patients. This process is heavily regulated by various government agencies to ensure that the medicines are safe and effective. The pharmaceutical manufacturing process usually involves multiple steps, including the preparation of raw materials, the manufacturing of active pharmaceutical ingredients (APIs), and the packaging and labeling of finished products. To ensure patient safety, all pharmaceutical companies must adhere to strict regulations set by government agencies such as the Food and Drug Administration (FDA). These regulations are designed to protect patients by ensuring that medicines are safe and effective.

To help manage the ongoing supply disruptions, the health regulators have extended to 28 October 2022, serious shortage protocols (SSPs) for 12 of the 13 hormone replacement therapies (HRT). "The only HRT SSP set to expire on 29 July 2022 is for SSP021 Premique low dose 0.3mg/1.5mg modified-release tablets. After 29 July, there will be no need to restrict quantities of Premique tablets as its supply situation has now stabilised," said PSNC. In addition, the dose equivalence advice and endorsement guidance for SSP024 and SSP025 have been updated. SSP024 and SSP025 have been updated by DHSC to provide greater clarity to pharmacists on the dose equivalences to determine the appropriate quantity to supply. Pharmacists are asked to refer to the latest SSP versions and endorsement guidance published on NHSBSA's website.

Dentistry is one of the most important yet underappreciated professions in the world. Without dental professionals, our teeth would fall out, we wouldn't be able to eat correctly, and our overall health would suffer. That's why ensuring you're doing everything possible to succeed in dentistry is crucial. And one of the best ways to do that is to listen to the advice of those who have come before you. If you are looking for some great tips on how to make it in the world of dentistry, then you have come to the right place. Here are four pieces of advice that will help you succeed. ATTEND A REPUTABLE DENTISTRY SCHOOL To be a great dentist, you must start with an excellent education. And that means attending a reputable dentistry school. There are many different schools, so it's essential to do your research and find one that is right for you, and this article gives an example of a dentistry course program overview. Consider things like accreditation, curriculum, clinical experience, and more when deciding. Additionally, it's important to note that you don't necessarily need to attend the most expensive school to get an excellent education. There are many affordable schools out there that can provide you with everything you need to succeed.

Authorities in Northern Ireland have seized more than 242,000 unlicensed prescription tablets purchased online and destined for addresses throughout NI. The medicines seized include Diazepam, used for anti-anxiety treatment, Pregabalin, used for epilepsy and anxiety, steroids and Zopiclone. Other prescription medicines recovered included Tamoxifen, often used in the treatment of breast cancer and Salbutamol inhalers, frequently used in the treatment of asthma. "Co-operation between law enforcement agencies and government departments has led to the seizure of over 242,000 illegal and unlicensed tablets purchased online and destined for addresses throughout Northern Ireland," justice minister Naomi Long was reported as saying. The minister, together with health minister Robin Swann and assistant chief constable Mark McEwan PSNI were highlighting Northern Ireland's input to the global, Interpol co-ordinated Operation Pangea XV, which saw multiple packages of tablets intercepted and seized, with a street value of almost £250,000. She praised the concerted efforts made by PSNI, Border Force and officials from the Department of Health Medicines Regulatory Group during a specific week of action in June.

An alliance of companies has pledged to ensure equitable access to vaccines and treatments for pandemics, as the friction around intellectual property rights for Covid-19 interventions between the pharmaceutical industry and developing nations endures. At the heart of the plan is a commitment to set aside part of the production of vaccines and treatments upfront for vulnerable populations in low-income countries when the next pandemic arises, given how fragmented access to Covid tools has left many populations unprotected. In order to do better next time - and without knowing which companies will develop the first drugs and vaccines for the next pandemic - having the industry collectively make this commitment is potentially transformative, said Thomas Cueni, head of the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA). The pledge, called the Berlin Declaration, was made on July 19 by members of the global pharmaceutical industry group that include many of the companies involved in developing Covid interventions, such as AstraZeneca, GSK, Moderna, Pfizer and Merck. The declaration is not legally binding. However, if a company that signed on reneges on its vow, it would face grave consequences in the court of public opinion, said Cueni.