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An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death. The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB). Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced cognitive decline by 27% in patients with early Alzheimer's in a study published last year. The results drove Lilly's shares to a record high, up more than 6% at $429.85. Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory. "It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful." Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.

Drug addiction poses a serious challenge since it impacts one's physical and mental health. However, the good news is that individuals who complete a drug rehabilitation program can overcome this problem. If you are interested in providing rehab services, there are a couple of things you should know. Read on to learn how to operate a rehabilitation clinic flawlessly. KNOW THE NEEDS OF YOUR CLIENTS The main purpose of drug rehab is to help different people overcome addictions. It is designed to heal the body and mind from the negative effects of addiction. It also teaches the affected individuals to learn to live without using substances. Therefore, your first step is to conduct a comprehensive assessment of each client to formulate a personalized treatment plan. Everyone has unique needs in their recovery journey. Your rehab program can start with detox which is designed to rid the body of substances, although it does not treat addiction. The person affected undergoes different therapies during treatment. Therapy helps them deal with the issues that cause substance abuse and teach them healthier ways of life. Various therapies will be applied throughout the entire treatment process. Therefore, you must choose a suitable therapy for each individual. For instance, motivational interviewing and cognitive behavioral therapy are the most common.

The recent announcement that Royal Mail will be partnering with distance selling pharmacy (DSP) giant pharmacy2U highlights how standards of regulatory enforcement are being ignored to accommodate the DSP model. The brunt of these double standards hinges around the levelling down of temperature enforcement standards by the Medicines and Healthcare products Regulatory Agency (MHRA) which demands mapping must be audited from the point of dispensing to the patient. The MHRA has a well recognised duty to ensure medicines reach patients in a safe condition. The current anomaly appears to turn a blind eye to this step in the supply chain at the point the wholesaler releases goods to the pharmacy hub. Equally the training on delivering medicines safely and effectively direct to patients should apply fully to all hubs including DSPs. Why is it that DSPs are being treated differently to bricks and mortar pharmacies? It's essentially the same patients receiving the same medicines from the same wholesalers. A further regulatory disparity exists around how parcels must be "tracked and signed for" to be reasonably certain medicines are delivered into the hand of the intended recipient, as per existing regulations. Clearly an untracked, unsigned package cannot be guaranteed to finish in the hands of the intended recipient. There is a very real possibility that such omission could lead to community pharmacy closures which will, in turn, lead to unemployment and a reduction in the care services. At a time when integrated care systems have just gone live, the removal of vital support services leading to further inequalities is the wrong message for both providers and patients alike.

Are you feeling overwhelmed about the MCAT? You're not alone! The MCAT is a challenging test that can feel daunting for even the best students. But don't worry, this article is here to help. This blog post will discuss six clever strategies that will help you pass the MCAT successfully. Follow these tips and you'll be on your way to achieving your dream score. ENROLL IN A PREP COURSE One of the first things you should do when preparing for the MCAT is to enroll in a prep course. Keep in mind that the right MCAT prep course will provide you with the resources and support you need to succeed. Additionally, it can help to take practice tests under simulated testing conditions. This will help you get used to the format of the test and reduce your anxiety on test day. In choosing a prep course, make sure to pick one that is reputable and has a good track record. You should also make sure that the course is affordable and offers a schedule that fits your needs. If possible, you can also take practice tests that are offered by the course. This way, you can get an idea of the type of questions that will be on the test. JOIN A STUDY GROUP Many people find that studying in a group is more effective than studying alone. When you join a study group, you'll have the opportunity to discuss difficult concepts with your peers. Additionally, you'll be able to hold each other accountable and stay on track with your studies. If you're not sure where to find a study group, ask your friends or classmates if they're interested in forming one. You can also check online forums or look for groups that have already been established.

Community pharmacists are readily accessible healthcare providers and medicine experts in the community setting and their counsel is often sought by patients and consumers on a number of subjects including the use of dietary supplements. Their role in the sale of and advice regarding natural health and drug alternatives has never been more relevant. The recent National Health Service (NHS) Interim People Plan calls for the NHS to put all staff front and centre of the way it operates and identifies pharmacists as a critical part of multidisciplinary teams, providing care across a wide range of increasingly complex patient needs. Despite existing demand to counsel patients on a vast range of medicines, more and more consumers are looking to their pharmacist to support and enhance their knowledge regarding the relevance of a growing range of supplementary nutrients now available. Nutritional supplementation is increasingly becoming the consumer's first choice for 'drug free' treatment or natural prevention that provides a true sense of taking control, which the prescription process often denies them. Historically the immense benefits provided by the NHS have instilled a general abdication of our personal health control, leaving us to rely on the health service to treat and cure as necessary. As our NHS has become visibly over-stretched we begin to realise what the rest of the world has known for centuries - good health is based primarily upon nutritional robustness. It may be stating the obvious but there is an excellent source of incremental revenue for the pharmacist who is willing to provide space to and advice for nutritional supplements.

Addiction is a difficult disease to deal with, both for the person who is struggling with it and for their loved ones. If you have a family member who is battling addiction, it can be hard to know what to do to help them. The good news is that there are things you can do to support your loved ones and improve their chances of recovery. In this blog post, we will discuss six ways that families can help their loved ones struggling with addiction. 1. EDUCATE YOURSELF ABOUT ADDICTION AND WHAT YOU CAN DO TO HELP To truly be able to help a family member who is struggling with addiction, you first need to educate yourself about the disease. This means learning about what causes addiction, how it affects the mind and body, and what you can do to support your loved one through their recovery journey. There are plenty of resources available online and at your local library that can help you learn more about addiction. You can also attend support groups for families of addicts, which can provide valuable information and emotional support. If you take the time to educate yourself about addiction, you'll be in a much better position to help your loved one through their struggle.

Pharmacists, along with workers from other public sector workplaces, marched on 8 September demanding that the Scottish government take all available action to mitigate the biggest reduction in living standards workers will have experienced for generations. Pharmacists Defence' Association (PDA) members participated in the Scottish Trade Unions Congress (STUC) march to let the government know that "Scotland demands better". Paul Flynn, PDA national officer, said: "Pharmacists will be unwelcomely familiar with diminished purchasing power and a squeeze on household budgets for patients, colleagues and pharmacists but what we will see this year and into 2023 will make previous experience pale by comparison." The march organised by STUC saw thousands of workers, activists and concerned individuals march through the centre of Edinburgh's Historic Old Town in good spirits while bearing flags and banners, chanting, singing, and calling for change in Scotland.

To support the mental health and wellbeing of pharmacists, the Royal Pharmaceutical Society (RPS) is running its fourth annual Workforce Wellbeing survey, in partnership with Pharmacist Support. This year it's focussed on exploring some of the obstacles that prevent workforce wellbeing measures being implemented in practice. It's vital that workplace supports good mental health and wellbeing and provides the right environment to help prevent the negative effects of working under intense pressure. RPS urges: "Please complete the survey as soon as you can. It's anonymous, open to pharmacists in all settings including students and you don't need to be a member of RPS to take part." "We'll take the results of the survey to governments across Great Britain, the NHS, and wider stakeholders to advocate for improvements to support the mental health and wellbeing of pharmacists."

After struggling with COVID, Hemant Petal is back to good health, and now he is on a mission to reduce "health inequalities". Speaking at the SIGMA Conference 2023, he spoke about his new role as Clinical Lead, Health Inequalities and Population Health Management, SE Essex Alliance, Essex ICB. "So, my new role is outside pharmacy, nothing to do with pharmacy. But it is important, I feel that I share some of my insights about the work that I'm doing that might benefit you," he said. Elaborating on the role of integrated care boards (ICBs), he said that they are designed to enhance coordination and collaboration across different healthcare providers and settings. The representatives from hospitals, community services, retail and social care meet on a monthly basis to "look at where there are issues to be resolved, perhaps what can be done to improve the healthcare services."

David Webb has been appointed as the new chief pharmaceutical officer (CPO) for England. He will take over from Dr Keith Ridge who steps down next month after serving the role for sixteen year. Webb is currently chief pharmacist and clinical director for pharmacy and medicines optimisation at Guy's and Thomas's NHS Foundation Trust, London. Sharing the news of his appointment on Twitter on Friday afternoon (January 7), he said he was "really delighted and honoured" to be named the CPO for NHS England and that he was as the appointed Chief Pharmaceutical officer for "looking forward to working with pharmacy leaders, colleagues & teams across all sectors from February." He also extended his gratitude to the outgoing CPO for his "outstanding contribution" who, in turn, congratulated Webb and said it was "an honour to be handing over to him". In the same message, Dr Ridge thanked "all the great people I've worked with over the last 16 years for your support, friendship, good humour, great ideas & challenge. I wish you all well for the future."

January 1 2022, the No Surprises Act (NSA) went into effect, opting for more transparency in medical billing and requiring physicians to provide Good Faith Estimates. While a great win for patients, the arbitration it creates between provider and insurer could see many solo/private practices closed permanently.

The feet allow you to get around, give you balance and support body weight when you walk or run. Keeping feet well cared for is not just a matter of vanity. Some simple daily care can prevent diseases caused by fungi and bacteria and pain in the soles. To ensure smooth and healthy feet, some care is essential to maintain a good appearance and comfort. Do you want to know more about it? Continue reading and discover four efficient tips to keep your feet well cared for. SKIN HYDRATION WATCH YOUR NAILS WEEKLY EXFOLIATION FOOT HYGIENE As you can see, maintaining daily care is essential for those who want to have well-treated feet, regardless of their age or sex. After all, they play an essential role in your health, well-being, and quality of life. Therefore, they need attention so that you can walk safely and confidently. Please ensure you make frequent visits to a healthcare professional to check your feet for sensation and pulses at least yearly.

When it comes to supplements, more and more people are starting to become interested in them. This is because supplements have a lot of benefits that can improve a person's health in many ways. However, with the increasing popularity of supplements also comes an increase in the number of low-quality and ineffective supplements on the market. Because of this, it is important for people who are interested in taking supplements to know how to choose quality ones that will be beneficial to their health. In this article, we will discuss some tips on how to do just that. CHOOSE SUPPLEMENTS FROM A REPUTABLE COMPANY Finally, one of the best ways to ensure that you're getting a quality supplement is to choose one from a reputable company. There are many different supplement companies out there, but not all of them are created equal. Some companies are more interested in making money than they are in providing their customers with safe and effective products. Therefore, when you're looking for supplements, it's important to do some research on the different companies that sell them. See if there have been any complaints filed against the company or if their products have been recalled by the FDA. Also, look for customer reviews of the company's products to see what other people have thought about them. As explained by the folks from Supplement First, A good supplement company will have no problem providing you with this information and will be happy to answer any questions you have. Doing some research on the company beforehand can save you a lot of time and money in the long run.

To curb the supply issue of HRT medicine, the government has taken a further action by issuing SSPs for Oestrogel, Ovestin cream, Lenzetto transdermal spray and Sandrena gel sachets - with appropriate alternatives. The move aims to allow community pharmacists to supply specified alternatives to the prescribed HRT products without needing to seek authorisation from the clinician who has prescribed the medicine. The regulator said that the availability of Premique Low Dose has impoved 'thanks to SSPs issued on 29 April to restrict dispensing for Oestrogel, Ovestin and Premique Low Dose to three months' supply'. "Since these measures were implemented, further deliveries of all three products have been made, with Premique Low Dose returning to good availability this week. The manufacturers of Oestrogel and Ovestin, as well as suppliers of alternative HRT products, are taking action to increase UK supply." It added, "SSPs restricting prescriptions to a maximum of three months' supply will also be issued for substitute products, as a precautionary measure to ensure the supply of those substitutes is maintained."

The UK Health Security Agency (UKHSA) has advised self-isolation for people diagnosed with monkeypox to reduce the risk of spreading the infection. Household members are at the highest risk of becoming infected from a case within their house. The new guidance advises people with monkeypox infection to take steps to try and limit transmission within the household. "Monkeypox infection mainly spreads between people through direct, skin-to-skin contact, including sexual contact. Infection can also be spread via contaminated objects such as linen and soft furnishings," said UKHSA. The guidance advises that, where possible, cases are encouraged to sleep and eat in a separate room and use a separate bathroom to their household if possible. Good hygiene measures, to follow at all times, have also been set out. It suggests, "Where the use of a separate room isn't possible, cases should avoid physical contact and keep at least three steps (one metre) away from all household members. It is particularly important that they avoid close contact with young children, pregnant women and immunosuppressed people as they may be at higher risk of serious illness."

The Omicron variant of coronavirus is less likely to cause long Covid than previous variants, according to the first peer-reviewed study of its kind from the UK. Researchers at King's College London, using data from nearly 100,000 people who logged their Covid symptoms via an app, found the odds of developing long Covid after infection were 20 per cent to 50 per cent lower during the Omicron wave in the UK compared to Delta. The figure varied depending on the patient's age and the timing of their last vaccination. Long Covid, which includes prolonged symptoms ranging from fatigue to 'brain fog', can be debilitating and continue for weeks or months. It is increasingly being recognised as a public health problem, and researchers have been racing to find out if Omicron presents as big a risk of long Covid as previously dominant variants. The study from King's is believed to be the first academic research to show Omicron does not present as great a risk of long Covid, but that does not mean long Covid patient numbers are dropping, the team said. While the risk of long Covid was lower during Omicron, more people were infected, so the absolute number now suffering is higher. "It's good news, but please don't decommission any of your long Covid services," lead researcher Dr Claire Steves said, appealing to health-service providers.

We all know that clothes can make us look and feel good. But did you know that they can also be used to relieve some common health issues? That's right - by choosing the right fabrics and materials, you can help alleviate conditions like skin irritations, back pain, and even headaches. So the next time you're feeling under the weather, reach for your wardrobe first - it just might hold the key to feeling better. COMPRESSION SOCKS FOR DIABETES Compression socks for diabetes have become an invaluable tool for people with diabetes to keep their lower legs healthy. Wearing compression socks can help increase circulation in diabetic patients, which is incredibly important for the health of their feet and ankles. Additionally, if the patient suffers from swelling or poor blood circulation - compression socks can help reduce those negative side effects. As a result of wearing these specialty socks, many diabetics are kept more comfortable and experience less fatigue in their legs throughout the day. With many different sizes and varieties available - it's easy for anyone suffering from diabetes to find the perfect pair of compression socks to suit their specific needs and lifestyle. There are various diabetic stockings designed for men and women. Take the time to find the right pair for you.

Proper drug storage is essential to ensure the safety of yourself, your family, and those around you. This is especially important if you are taking multiple medications and need to keep track of them all. Knowing how to store drugs correctly can help prevent misuse or accidental ingestion by children or pets. Here are six important guidelines about proper drug storage that everyone should follow: 1. KEEP ALL MEDICATIONS IN THEIR ORIGINAL, LABELED CONTAINERS: Using alternative storage containers can make it difficult to identify medications or keep track of expiration dates. Keeping medications in their original containers also prevents accidental misuse and helps ensure that the correct dosage is taken. In addition, it's important to store all medications out of reach of children and pets. Also, keep medications in a cool, dry place away from direct sunlight. For example, a medicine cabinet in the bathroom or kitchen is a good option. 2. DISPOSE OF EXPIRED MEDICATIONS: Expired medications can be less effective and even potentially harmful if taken, so it's important to regularly check expiration dates and get rid of any outdated medications. The best way to dispose of old drugs is to take them to a drug collection site. If no such sites are available, mix the medication with something like coffee grounds, put it in an opaque container, and then throw it away in your trash bin. Never flush expired medication down the toilet unless instructed by your pharmacist or healthcare provider! 3. STORE DRUGS IN A COOL, DRY PLACE: Extreme temperatures can cause medications to break down and become ineffective. To avoid this, keep all drugs away from direct sunlight, heat sources, and moisture. A medicine cabinet or drawer in the bathroom is an ideal spot for storing most drugs, but some require special storage conditions (more on that below). Different medications should also be separated from one another to avoid confusion and stored differently. For example, if a

While Northern Irish business groups has welcomed the certainty a new EU-UK deal on post-Brexit trade rules for the region provided, the pharmaceutical industry too has expressed cautious optimism. In his speech on the Windsor Framework on Monday (February 28) Prime Minister Rishi Sunak said the agreement "delivers a landmark settlement on medicines". "From now on, drugs approved for use by the UK's medicines regulator will be automatically available in every pharmacy and hospital in Northern Ireland," he announced. The National Pharmacy Association's Northern Ireland manager Anne McAlister expressed a sense of cautious optimism. She said: "While the devil may yet be in the detail, the Windsor Framework would appear to be good news for pharmacies in Northern Ireland. It seems to address the main concerns we have expressed about medicines supplies to NI, but we want to examine the small print to ensure the new arrangements meet the needs of our members and the patients they serve.

Representatives from the national community pharmacy bodies will brief the MPs on the severe challenges facing community pharmacies on Tuesday (21 March) at a roundtable summit. The roundtable summit will include discussions on the urgent action needed to address the current severe challenges being faced by community pharmacy, as well as the sector's role in the upcoming Primary Care Recovery Plan, said PSNC. The Parliamentary event this week has been coordinated by PSNC as part of the joint #SaveOurPharmacies campaign which exceeded 30,000 signatories in a week. The Association of Independent Pharmacies (AIM), the Company Chemists' Association (CCA), the National Pharmacy Association (NPA) and PSNC will take part at the event. A spokesperson for the #SaveOurPharmacies campaign group said: "30,000 signatures in a week indicates a high level of underlying public support for community pharmacy and it's a good start to the #SaveOurPharmacies campaign. A petition by itself won't change the world, but it works as a kind of drumbeat for the campaign, giving forward momentum, and it's a really easy way to express your opinion. We hope the new window poster - along with all the resources available at saveourpharmacies.co.uk - will help as many pharmacies as possible to drum up support from their patients, and we're really grateful to Communications International Group for helping us to print and distribute this.