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An independent committee at the National Institute for Health and Care Excellence (NICE) has developed a menu of options to treat depression in adults. The first guideline to identify, treat and manage depression has been created after looking at the evidence of treatment on various aspects of depression. The guideline allows patients to select the best suited cure for them through a shared decision-making process between them and their healthcare practitioner. Patients with less severe depression can choose a first-line treatment option from the menu, such as cognitive behavioural therapy (CBT), exercise, counselling or psychotherapy. Similarly, those with a severe depression can select from a range of psychological interventions and antidepressant medication. As per data released by the Office of National Statistics, around 17 per cent of people aged 16 years and over in Great Britain experienced some form of depression in summer 2021, higher than the previous year.

The Pharmacists' Defence Association (PDA) is playing a vital role in helping pharmacists who are dealing with stress at the workplace. It launched its new awareness factsheet 'It's Time to Address Stress' last week. The factsheet looks at the causes and symptoms of stress in the workplace and provides advice on ways pharmacists can access support and improve working conditions. The association said that it recognises the well-being services offered by employers and specialist charities such as the PDA's charity partner Pharmacist Support play an important part in helping pharmacists who may be experiencing stress. However, the PDA is also committed to working with members to challenge employers to provide well workplaces and to help them to make real impact changes. This can be done by addressing the causes of stress and fulfilling their responsibilities to their employees. It added: "Under the management of Health and Safety at Work Regulations 1999, employers are required by law to protect employees from harm. Their legal obligations include identifying hazards and risks and implementing ways to reduce or eliminate them. The PDA's new factsheet highlights the importance of employers recognising the hazards causing stress as the health and safety issues they are."

A study conducted by Michigan Medicine revealed that individuals who experience type 2 diabetes over an extended period are increasingly prone to experiencing alterations in their brain structure. A group of scientists examined data from 51 middle-aged Pima American Indians who were diagnosed with type 2 diabetes. They employed a set of memory and language assessments known as the NIH Toolbox Cognitive Battery, developed by the National Institutes of Health, alongside MRI scans. These analyses aimed to establish the connection between diabetes, cognitive function, and the composition of the brain. Brain imaging suggested that study participants with longer durations of type 2 diabetes had decreased mean cortical thickness and gray matter volumes, and an increased volume of white matter hyperintensities. The MRI results, researchers say, indicate the negative effects longstanding diabetes may have on brain health outcomes and emphasise the importance of preventing early onset type 2 diabetes.

The price concession for Atorvastatin 80mg has been increased to £3.91 from the previously set £3.45 for prescriptions dispensed in July, the Community Pharmacy England has said. The Department of Health and Social Care additionally introduced a concession price of £3.38 for Atorvastatin 20mg. "In July, our Dispensing and Supply Team experienced an unusually high influx of reports from pharmacies struggling to acquire Atorvastatin 80mg tablets at the listed Drug Tariff price," said CPE. CPE requested a price concession early in the month. However, after extended discussions, an agreement on the price wasn't reached. Consequently, on July 31st, the DHSC imposed a concession of £3.45. Addressing enduring pharmacy concerns over the pricing, CPE intensified advocacy with DHSC. This endeavour resulted in the revision of the Atorvastatin 80mg tablet concession price to £3.91 for prescriptions submitted and dispensed in July. According to CPE, this adjusted price sufficiently covers costs as reported by the majority of pharmacy owners. However, DHSC has refrained from modifying concessionary prices for the other two requested lines by CPE. DHSC communicated that their team's data collection for July, employing real-time sales and volume data, was incongruent with the adjustment of these prices, CPE further said.

The UK pharmaceutical industry experienced a substantial increase in public trust and favourability during the Covid-19 pandemic, according to a new poll. This trend appears to be persisting with the study showing a generally favourable view of the sector. The recent survey, conducted by Ipsos and commissioned by Association of the British Pharmaceutical Industry (ABPI), represents the third instalment in a series that began in 2021. This ongoing study targets members of the public, healthcare professionals, and parliamentarians. The study once again underscored a favourable perception of the sector with 67 per cent of respondents recognising that the pharmaceutical industry produces safe and effective medicines using cutting-edge technologies. Moreover, a majority agrees that it is a highly innovative field. Seven out of 10 people also trust the sector's readiness to address future pandemics, even as media attention on pharmaceutical companies returns to pre-pandemic levels. However, concerns arise regarding limitations in accessing new medicines due to cost pressures.

Digital pharmacy app Charac has raised over £1 million in debt and equity, bringing total funding to date for the London-based startup to £2.5m. Pharmacy Business understands while the majority of the new finance, worth about £1.2 million, comes from the National Pharmacy Association (NPA) coffer, the remainder is put forward by a number of individual pharmacy businesses. The pharmacy sector is in a state of crisis, experiencing nearly two closures per week over the past two years, Charac said in a statement. According to data from the NHS Business Services Authority, there are now only 11,026 community pharmacies in England, the lowest number since 2015. The current crisis is attributed to escalating operational costs, a shortage of staff, and diminished government financial support.

The General Pharmaceutical Council (GPhC) has urged health and care professionals to meet relevant regulatory standards amidst the shortage of GLP-1 receptor agonists (GLP-1 RAs). The council said: "We are concerned to hear that people with Type 2 diabetes are experiencing problems accessing GLP-1 receptor agonists (GLP-1 RAs). We know that these are being widely prescribed for weight loss purposes and in some cases prescribed off-label." "We recognise the adverse impact that shortages and supply chain issues can have on patients, the public and wider health and care teams. The Council understands that health and care professionals are using their professional judgement and making decisions in challenging situations, balancing a range of factors such as individual patient needs, wider public health and pressures and limitations on available resources such as medicines shortages or other supply chain issues.

The Centre for Pharmacy Post-Graduate Education (CPPE) has launched Menopause - an introduction for pharmacy professionals e-learning programme. The new Menopause: an introduction for pharmacy professionals e-learning programme aims to support pharmacist's to increase their knowledge and awareness of menopause and perimenopause, helping them to have initial conversations with those who need support. The programme teaches how to equip people experiencing menopausal symptoms with evidence-based information that allows them to make decisions about their own health management. This e-learning programme considers a range of topics, including the signs and symptoms associated with menopause and perimenopause, how a diagnosis is made and the national context supporting a growing role for pharmacy professionals in menopause care. It also discusses the benefits and risks of treatment options available, the common misconceptions that people may have about menopause and how to apply the evidence base to practice in order to help support decision making.

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New research has shown that chronic pain can be objectively measured using brain signals, a report in The Conversation said. According to the report, a team of researchers conducted a study using brain implants capable of recording neural signals over an extended period. Their aim was to identify reliable markers of chronic pain severity in four patients as they went about their daily lives. While pain is typically a subjective experience, there is still much to discover about how pain signals are processed in the brain. Previous studies often relied on artificial settings, and the relationship between acute and chronic pain circuits remained unclear. To investigate this further, the researchers surgically implanted electrodes in the brains of four patients experiencing post-stroke pain and phantom limb pain. Neural signals were recorded in specific brain regions associated with planning, expectation, and emotion. The patients were then asked to report their pain severity levels multiple times a day for up to six months. Machine learning models were developed to analyse the recorded brain activity signals and predict the patients' self-reported pain intensity scores.

The Company Chemists' Association (CCA) has published a 'pharmacy paradox paper' which outlines how community pharmacy can match the ambition amidst the workforce crisis. The sector is experiencing a workforce crisis, exacerbated by NHS recruitment of community pharmacists into primary care networks. Pharmacies are also facing a significant increase in demand on services. CCA said, "A stretched and reduced pharmacy workforce is having to deliver more and more. This is unsustainable." "Unless the tension between ambition and capacity is addressed, there is a risk that community pharmacies will not only not meet their potential, but the existing offer could be compromised." Therefore, the association has set out solutions to resolve the current paradox between ambition and reality.

Three pharmacists have collectively acquired Leyton Green, a community pharmacy on the outskirts of London Borough, as its owner, Raj Baxi, opts to retire after 15 years of service. The pharmacy, which processes an average of 2,697 items per month, was recently sold for an undisclosed sum, said Christie & Co, who facilitated the confidential transaction. The trio, led by Abdus Subhan, intends to drive the business forward by expanding the range of items and introducing advanced services. "After nearly 15 years in Walthamstow, we will miss our loyal customers, but we are pleased for the pharmacy to go to experienced operators," Baxi said.

Boots has welcomed job applications from LloydsPharmacy staff impacted by the news of closure of all its branches located in Sainsbury's before the end of 2023. The company is recruiting for more than 1,500 pharmacy roles nationwide. Vacancies span pharmacy roles at all levels - from Pharmacy Advisors (Dispensers) and Trainee Pharmacists to experienced Pharmacists looking to develop their careers. Sebastian James, Managing Director of Boots UK & ROI, said: "Pharmacies deliver vital healthcare in the heart of communities. News of the closure of LloydsPharmacy branches within Sainsbury's stores will no doubt have an impact on many talented pharmacists as well as their patients. "We have many roles available at Boots and welcome applications from LloydsPharmacy employees affected by the closures. Patients who are worried about their future pharmacy provision can check our store locator online to find out where their nearest Boots store is - our pharmacy team members are ready to help." There are over 2,200 Boots stores across the UK and 85% of the population live within 10 minutes of a Boots store.

The International Pharmaceutical Federation (FIP) in a report of a meeting of an international insight board published on Friday (27 January) highlighted the potential for pharmacists to close the existing gender gap in pain management. The insight board, assembled by FIP in Seville, Spain, in September 2022, was co-chaired by FIP vice president Professor Parisa Aslani. "Research indicates that pain experienced by women is underestimated and undertreated. Alarmingly, in addition to receiving less effective pain relief, evidence suggests that women with pain are more likely to be prescribed antidepressants," Prof. Aslani said. The insight board attributed much of this "gender pain gap" to implicit biases and put forward the view that pharmacy curricula and continuous professional development programmes must be able to provide adequate self-awareness and training to enable pain management without any bias. It also suggested ways in which pharmacists could be supported in addressing the gender pain gap in their practice.

There are few conditions that bring the degree of isolation, embarrassment and self-consciousness that bowel and urinary incontinence does. In the UK, about 14 million adults experience bladder control problems and 6.5 million have bowel control difficulties. Additionally, there are just under a million children in the UK experiencing continence conditions at any one time. Over £200 million is spent on personal incontinence products; this is in addition to over three times the same amount spent by the NHS. With a rapidly ageing population and unaddressed contributing factors, the significant financial burden, but importantly, the impact on the quality of life and dignity is devastating. We also know that cultural and communication difficulties can create barriers making treatment access and symptom alleviation more difficult. Considering the demography that this has a greater impact on - patients with a learning disability, non-English speakers and disabled patient - it becomes apparent this is a form of health inequality. However, pharmacy teams are best placed to tackle this head-on. Incontinence is the inability to control your bladder or bowel, so you accidentally lose urine from the bladder (urinary incontinence) or faeces from the bowel (bowel incontinence).

A bout 15 to 30 per cent of the UK population suffers from hay fever and there has been a definite increase in the number of moderate to severe hay fever sufferers, with sufferers experiencing more frequent and longer seasons. And now that the government has announced its plans for the easing of lockdown, community pharmacists can expect to see many more of their patients presenting with more severe symptoms than usual, as there will be more opportunities to spend time outside and be exposed to higher levels of pollen. Symptoms Common symptoms include sneezing, a runny stuffed up nose, itchy, watery eyes, nasal congestion and a general stuffed up feeling in the nose and throat. Some experience itching around the face and mouth, with an itchy palette, and burning sensation in the throat. Headaches and wheezing can also occur, as well as an overall achy feeling, or build-up of pressure in the facial area. The sinus area can become painful and constant nose blowing can leave sufferers with skin irritation. This can lead to tiredness and affect sleep, which in turn reduces energy.

The National Pharmacy Association (NPA) has partnered with training provider Skills 4 Pharmacy to provide Level 2 and Level 3 pharmacy apprenticeships to its members in England. Skills 4 Pharmacy is an experienced pharmacy apprenticeship training provider dedicated to initiating and developing the careers of pharmacy support staff and technicians. They manage the recruitment of apprentices, as well as their enrolment and training. The apprenticeship package offers a Level 2 Apprenticeship - Pharmacy support worker and Level 3 Apprenticeship - Pharmacy technician. Amerjit Singh, Managing Director at Skills 4 Pharmacy said: "As a member for the last 23 years it is a great honour to be able to work alongside the NPA and promote apprenticeships. "As contractors we are facing challenging times, however I firmly believe that apprenticeship programmes which upskill and empower our workforce are essential for our future survival. Apprenticeships are a great way to build a strong talent pipeline and bring new skills to pharmacies.

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Professional translators recreate texts, not simply matching word-for-word, but understanding the underlying meaning, purpose, and interpretation of the original language, and reproduce it using appropriate terminology and structure to ensure there is no potential for misunderstanding. An experienced technical translator addresses conventions to ensure the meaning of the information is preserved, using medical expertise and quality review processes to adapt documentation to meet the needs of patients, medical practitioners, and peers. Attention to detail is fundamental to medical translations and a non-technical translation is an unacceptably high risk for any organisation involved in publishing or circulating medical information of any kind. WHAT IS MEDICAL TRANSLATION? Medical translation is a technical process where capable translators reproduce content or documentation used anywhere in the medical industry, including psychiatry, systematic reviews, tuition and training, patient communications for pharmaceutical translation services. Important clinical trial translations can include labelling, prescriptions, medical devices and patient records, with millions of medicines and treatments used globally and written in multiple languages. Qualified medical translators must have exceptional linguistic skills but also a thorough understanding of medical sciences in all the native languages concerned. However, the complexity of translating one label or one document into several languages can mean that organisations may assume a simple translation is sufficient - when it is anything but!

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