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The Royal Pharmaceutical Society (RPS) recently announced a valuable addition to their e-library collection: the Maudsley Deprescribing Guidelines, authored by renowned experts Mark Horowitz and David Taylor. Designed to assist pharmacists and clinicians in recognising and appropriately treating withdrawal effects of medications, the guidelines have garnered praise from industry figures like Peter Pratt, National Speciality Advisor for Mental Health Pharmacy and RPS Fellow. This initiative responds to the increasing demand for guidance on safely reducing or discontinuing psychiatric medications, providing comprehensive support for clinicians and patients alike. Drawing on insights from contributors to The Lancet Psychiatry, the handbook offers step-by-step instructions for tapering antidepressants, benzodiazepines, gabapentinoids, and z-drugs, along with troubleshooting strategies.