The phenomenon where a mutation overrides another genetic defect is known as genetic suppression and it is not unique to yeasts. Genome sequencing studies have revealed individuals who remain healthy despite carrying catastrophic inborn errors whose usual harmful effects are somehow masked by other unknown changes in their genomes.

"What is Skin in the Game? The phrase is often mistaken for one-sided incentives: the promise of a bonus will make someone work harder for you. For the central attribute is symmetry: the balancing of incentives and disincentives, people should also penalized if something for which they are responsible goes wrong and hurts others: he or she who wants a share of the benefits needs to also share some of the risks."

The article describes this dynamic, in which the rise of China plays a central role, and argues that the dynamic between state geoeconomic measures and corporate statecraft will define how far the global economy will depart from the current market orientation and how much it will be subject to national strategic choices.

Globally, the USA has recorded the highest number of COVID-19 cases and deaths,1 and still needs to simultaneously respond to another looming potential pandemic. The rise in multidrug-resistant bacterial infections that are undetected, undiagnosed, and increasingly untreatable threatens the health of people in the USA and globally. In 2020 and beyond, we cannot afford to ignore antimicrobial resistance (AMR).

In hierarchical relationships-between employer and employee, parent and child, or teacher and student-social rank is understood and bolstered by social norms. In contrast, symmetric relations-between friends, neighbors, classmates, or coworkers- are equitable. One party can't claim dominance over the other. But when ambiguity persists about who holds the upper hand, the likelihood of conflict increases. Animal research yields parallel findings, suggesting that when two animals of the same species are similarly sized, conflict is more likely than when there is a size disparity.

We need to take a hard look at what parts of the world are critical to the security of the West and rethink how to make its alliances work again. The following geopolitical reality is still true today: The United States has to ensure that no power hostile to its interests can assert exclusive control over Eurasia, including the European rimland. Today preventing China's domination of Eurasia should be our overarching strategic objective, and to achieve this we need to focus on three fundamentals: 1) Prioritize Eurasia and stop draining our military resources in secondary theaters; 2) invest in allies who see their interests directly aligned with ours and are willing to assume the attendant risk; and 3) decouple U.S. strategic industries from China's and redefine the rules of international trade to ensure equitable competition.

Over the past few decades, researchers have gathered evidence suggesting that tensegrity is a key design principle in nature, as it applies to a number of biological systems, including bodies, organs, cells and molecules. Tensegrity structures could thus also prove valuable for the development of bio-inspired robots, as it may enable the creation of systems that closely resemble those observed in living organisms.

Isomorphism

Actions taken to mitigate the threats of coronavirus disease 2019 (COVID-19) to human life and welfare have inadvertently resulted in a natural experiment offering unanticipated insight into how human behavior affects animal behavior (1). Worldwide, elective quarantine and stay-at-home orders have reduced use of public spaces and transportation networks, especially in cities. Anecdotal media accounts suggest that restricted movement has elicited rarely observed behaviors in commensal and peri-urban animals (2). Though not all of the reports have proven to be accurate (3), widely publicized observations like coyotes crossing the normally heavily trafficked Golden Gate Bridge in the San Francisco (SF) Bay Area (California, USA) have provoked widespread fascination with the prospect that animals rapidly move back into landscapes recently vacated by humans.

People feel they understand complex phenomena with far greater precision, coherence, and depth than they really do; they are subject to an illusion-an illusion of explanatory depth. The illusion is far stronger for explanatory knowledge than many other kinds of knowledge, such as that for facts, procedures or narratives. The illusion for explanatory knowledge is most robust where the environment supports real-time explanations with visible mechanisms. We demonstrate the illusion of depth with explanatory knowledge in Studies 1-6. Then we show differences in overconfidence about knowledge across different knowledge domains in Studies 7-10. Finally, we explore the mechanisms behind the initial confidence and behind overconfidence in Studies 11 and 12. Implications for the roles of intuitive theories in models of concepts and cognition are discussed.

For decades, scientists have been using a classical experimental search task-which involves placing a single rat in a complex maze to search for a reward-to deepen understanding of navigation, memory, and learning. However, rats are highly social animals that build and live in complex burrow systems in nature. Yet very little is known about how they explore as a group. In the new study, researchers from institutes in Germany and Hungary turned the classical experimental search task into the first experimental study on rodent group search behavior in a confined maze.