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Numerical results show that school closure alone would have limited benefit in reducing the peak incidence (less than 10% reduction with 8-week school closure for regions in the early phase of the epidemic). When coupled with 25% adults teleworking, 8-week school closure would be enough to delay the peak by almost 2 months with an approximately 40% reduction of the case incidence at the peak. This is critical to reduce the burden on the healthcare system in the weeks of highest demand. Moderate overall reduction of the final attack rate (15%) would also be achieved. Results across regions are qualitatively similar, with differences

Natural hazard events, such as storms, floods, and wildfires, entail huge and growing costs all over the world, but they can also be occasions for countries to implement risk-reducing changes. There is no research consensus on whether natural hazard events lead to policy modifications or, instead, contribute to stability and preservation of existing solutions. Knowledge in this area to date has been based on individual case studies, and global trends have not been studied.

"n a recent article in the New York Times, the development economist Seema Jayachandran discusses three studies that used Randomised Controlled Trials (or RCTs) to understand the benefits of enhancing the self-worth of poor people. Despite wide differences in context, all the cases explore the viability of 'modest interventions' to 'instill hope' in marginalised communities, concluding that 'remarkable improvements' in the quest for poverty reduction are possible."

Noise limits the performance of modern quantum technologies. However, particles traveling in a superposition of paths can bypass noise in communication. A collaboration between the Universities of Hong-Kong, Grenoble and Vienna, as well as the Austrian Academy of Sciences, under the lead of Philip Walther, reveals novel techniques to reduce noise in quantum communication. The results, published in the latest issue of Physical Review Research, demonstrate that quantum particles traveling in a superposition of paths enable noise reduction in communications.

Using two independent single-cell approaches, we identified a shift in the overall immune cell composition in cavefish as the underlying cellular mechanism, indicating strong differences in the immune investment strategy. While surface fish invest evenly into the innate and adaptive immune systems, cavefish shifted immune investment to the adaptive immune system, and here, mainly towards specific T-cell populations that promote homeostasis. Additionally, inflammatory responses and immunopathological phenotypes in visceral adipose tissue are drastically reduced in cavefish. Our data indicate that long-term adaptation to low parasite diversity coincides with a more sensitive immune system in cavefish, which is accompanied by a reduction in the immune cells that play a role in mediating the pro-inflammatory response.

The analysis of questionnaires often involves representing the high-dimensional responses in a low-dimensional space (e.g., PCA, MCA, or t-SNE). However questionnaire data often contains categorical variables and common statistical model assumptions rarely hold. Here we present a non-parametric approach based on Fisher Information which obtains a low-dimensional embedding of a statistical manifold (SM). The SM has deep connections with parametric statistical models and the theory of phase transitions in statistical physics. Firstly we simulate questionnaire responses based on a non-linear SM and validate our method compared to other methods. Secondly we apply our method to two empirical datasets containing largely categorical variables: an anthropological survey of rice farmers in Bali and a cohort study on health inequality in Amsterdam. Compare to previous analysis and known anthropological knowledge we conclude that our method best discriminates between different behaviours, paving the way to dimension reduction as effective as for continuous data.

"Managing plastics has become a grand and complex environmental challenge, and plastic packaging clearly warrants current efforts on reductions and coordinated material recovery and recycling," said Gregory Keoleian, senior author of a paper published Aug. 25 in the journal Environmental Research Letters.

Recent major surveys show that reductions in genomic complexity - including the loss of key genes - have successfully shaped the evolution of life throughout history.