He died in June 1604, probably from plague, at King's Place in Hackney, located in the London suburb of Stratford. He left no will
and is presumed buried in St Augustine's church in the same parish.
Contemporary testimony that he may be buried elsewhere is provided by
Percival Golding, the youngest son of Arthur Golding, the uncle of De Vere.
Golding wrote twenty years after De Vere's death that the 17th Earl "died at
his house at Hackney in the month of June 1604 and lies buried at Westminster
[Abbey]."